• Proceedings of the KSME Conference
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• 2008.11a
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• pp.222-227
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• 2008

This study is focused on an integrated numerical modeling enabling one to investigate the dynamic behavior and failure of 2-D textile composite and 3-D orthogonal woven composite structures weakened by micro-cracks and subjected to an impact load. The integrated numerical modeling is based on: I) determination of governing equations via a three-level hierarchy: micro-mechanical unit cell analysis, layer-wise analysis accounting for transverse strains and stresses, and structural analysis based on anisotropic plate layers, II) development of an efficient computational approach enabling one to perform transient response analyses of 2-D plain woven and 3-D orthogonal woven composite structures featuring the matrix cracking and exposed to time-dependent loads, III) determination of the structural characteristics of the textile-layered composites and their degraded features under various geometrical yarn shapes, and finally, IV) assessment of the implications of stiffness degradation on dynamic response to impact loads.

• The Plant Pathology Journal
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• v.35 no.5
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• pp.406-416
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• 2019

Strawberry, an important fruit crop, is susceptible to a large number of pathogens that reduce fruit quality and productivity. In this study, the effect of a biostimulant prepared from Ascophyllum nodosum extract (ANE) (0.1%, 0.2%, and 0.3%) was evaluated on powdery mildew progression under greenhouse and field conditions. In the greenhouse, application of 0.2% ANE showed maximum reduction in powdery mildew progression as compared to the control. Forty-eight hour post-inoculation, foliar spray of 0.2% ANE reduced spore germination by 75%. Strawberry leaves sprayed with ANE showed higher total phenolic and flavonoid content in response to powdery mildew infection. Furthermore, application of ANE elicited defense response in strawberry plants by induction of defense-related enzymes, such as phenylalanine ammonia lyase, polyphenol oxidase, and peroxidase activity. In field conditions, foliar spray of 0.2% ANE showed a reduction of 37.2% of natural incidence of powdery mildew infection as compared to the control. ANE sprayed plant also reduces the severity of powdery mildew infection under natural conditions. These results indicate that application of ANE induces the strawberry plant's active defense against powdery mildew infection by induction of secondary metabolism and regulating the activities of defense-related enzymes.

• Journal of the Korean Society of Propulsion Engineers
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• v.23 no.1
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• pp.108-115
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• 2019

The thermal response of elastomeric insulators used as protection against high-temperature and high-pressure combustion gases varies depending on their composition and thermal environment conditions. In this paper, the thermal response characteristics of elastomeric insulators in different mixing environments were compared. Tests to determine thermal protection performance were carried out using a thermal protection rubber evaluation motor(TPREM), combustion gas velocities of 20 m/s and 100 m/s were tested at a chamber pressure of 1,000 psig. The pressure time curve of the chamber, the temperature time curve of the internal materials, the residual thickness and the thermal destruction depth of the test specimens were obtained. The results showed that the thermal protection performance of elastomeric insulators in different mixing environments was similar.

• Clinical and Experimental Pediatrics
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• v.52 no.6
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• pp.649-654
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• 2009

The immune system is comprised of cells and molecules whose collective and coordinated response to the introduction of foreign substance is referred to as the immune response. Defense against microbes is mediated by the early reaction (innate immunity) and the late response (adaptive immunity). Innate immunity consists of the epithelial barrier, phagocytes, complement and natural killer cells. Adaptive immunity, a more complex defense reaction, consists of activation of later-developed lymphocytes that, when stimulated by exposure to infectious agents, increase in magnitude and defensive capabilities with each successive exposure. In this review we discuss recent advances in important primary immune deficiency disorders of innate immunity (chronic granulomatous disease, leukocyte adhesion deficiency) and adaptive immunity (severe combined immune deficiency, Wiskott- Aldrich syndrome).

• Toxicological Research
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• v.25 no.4
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• pp.159-173
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• 2009

Nuclear factor erythroid derived 2-related factor-2 (Nrf2) is a master transcription regulator of antioxidant and cytoprotective proteins that mediate cellular defense against oxidative and inflammatory stresses. Disruption of cellular stress response by Nrf2 deficiency causes enhanced susceptibility to infection and related inflammatory diseases as a consequence of exacerbated immune-mediated hypersensitivity and autoimmunity. The cellular defense capacity potentiated by Nrf2 activation appears to balance the population of $CD4^+$ and $CD8^+$ of lymph node cells for proper innate immune responses. Nrf2 can negatively regulate the activation of pro-inflammatory signaling molecules such as p38 MAPK, NF-${\kappa}B$, and AP-1. Nrf2 subsequently functions to inhibit the production of pro-inflammatory mediators including cytokines, chemokines, cell adhesion molecules, matrix metalloproteinases, COX-2 and iNOS. Although not clearly elucidated, the antioxidative function of genes targeted by Nrf2 may cooperatively regulate the innate immune response and also repress the expression of pro-inflammatory mediators.

• Journal of the Korean Society of Safety
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• v.29 no.5
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• pp.22-28
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• 2014

This study is compare to model-based analysis and experimental data of the response characteristic of interior impulse noise. Interior impulse noise and the pressure response characteristics of the building structure on its analysis are presented the impulse pressure acting on the rear wall 90 N-sec. The force acting on the wall $CFD^{{+}{+}}$ which are compared measurement and simulation analysis. Results of simulation and measurement data were shown. In this study, a high dimension of the degree of virtual space in the numerical space of the lesser degree in order to calculate folding method was applied. The results of this study contribute safety evaluation and model development for the interior impulse noise that affects the basic data for the interior impulse noise model validate for the physical quantity prediction.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.20 no.10
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• pp.9-18
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• 2021

The cutting force in a cutting simulation is determined by the cutting conditions, such as cutting speed, feed rate, and depth of cut. The cutting force changes, depending on the material and cutting conditions, and is affected by the heat generated during cutting. The physical properties for predicting the cutting force use constitutive equations as functions of the hardening term, rate-hardening term, and thermal-softening term. To accurately predict the thermal properties, it is necessary to accurately predict the thermal-softening coefficient. In this study, the thermal-softening coefficient was determined, and the cutting force was predicted, using the response-surface method with the cutting conditions and the thermal-softening coefficient as factors.

• Journal of the Korean Society for Precision Engineering
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• v.33 no.10
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• pp.805-811
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• 2016

Prior to installation in a navy ship, shipboard equipment should be qualified by shock test requirements. The multi-function console mounted on the elastic platform of the ship should also withstand given shock loads. In this study, both real shock test methods, as well as numerical computer simulations using the finite element method were used to verify structural durability under shock load conditions. First, we used domestic test facilities to perform possible shock tests, including an impact hammer test, a drop table test and a shaker shock test. Full model tests satisfying the shock response spectrum level were performed. Thereafter, an analytical model of the complex console structure was built by the finite element method. Finally, numerical results were verified by modal test results of the real product and an FEA analysis was also performed with a full model transient response analysis.

• Journal of the Society of Disaster Information
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• v.15 no.3
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• pp.347-357
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• 2019

Purpose: The purpose of this paper is to present a method for effectively conducting discussion-based training in disaster response safety training. Method: To this end, we analyzed the disaster response training of developed countries and suggested the training scenarios by applying the war-game process that is currently applied in the operation planning of our military. Result: In one disaster situation, several contingencies could be identified, and supplementary requirements for the manual could be derived. Conclusion: Therefore, in conclusion, if the military war-game process is applied to the discussion-based training in disaster response safety training, effective training can be carried out.

• The Plant Pathology Journal
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• v.21 no.1
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• pp.47-54
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• 2005

Identification of host genes involved in disease progresses and/or defense responses is one of the most critical steps leading to the elucidation of disease resistance mechanisms in plants. Soybean mosaic virus (SMV) is one of the most prevalent pathogen of soybean (Glycine max). Although the soybeans are placed one of many important crops, relatively little is known about defense mechanism. In order to obtain host genes involved in SMV disease progress and host defense especially for virus resistance, two different cloning strategies (DD RT-PCR and Subtractive hybridization) were employed to identify pathogenesis- and defenserelated genes (PRs and DRs) from susceptible (Geumjeong 1) and resistant (Geumjeong 2) cultivars against SMV strain G7H. Using these approaches, we obtained 570 genes that expressed differentially during SMV infection processes. Based upon sequence analyses, differentially expressed host genes were classified into five groups, i.e. metabolism, genetic information processing, environmental information processing, cellular processes and unclassified group. A total of 11 differentially expressed genes including protein kinase, transcription factor, other potential signaling components and resistant-like gene involved in host defense response were selected to further characterize and determine expression profiles of each selected gene. Functional characterization of these genes will likely facilitate the elucidation of defense signal transduction and biological function in SMV-infected soybean plants.