• 제목/요약/키워드: defect type

검색결과 1,074건 처리시간 0.031초

Promoted Bone Regeneration by Nanoparticle-Type Sustained Release System of BMP-2 in Hydrogel

  • Chung, Yong-Il;Lee, Seung-Young;Tae, Gi-Yoong;Ahn, Kang-Min;Jeon, Seung-Ho;Lee, Jong-Ho
    • 한국고분자학회:학술대회논문집
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    • 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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    • pp.264-264
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    • 2006
  • The nanoparticle-hydrogel complex as a new bone defect replacement matrix, which is composed of the nanoparticles for the sustained release of BMP and the hydrogel for filling the bone defect site and playing a role as a matrix where new bone can grow, is presented. In vivo evaluation of bone formation was characterized by soft X-ray, MT staining, and calcium assay, based on the rat calvarial critical size defect model. The effective bone regeneration was achieved by the BMP-2 loaded nanoparticles in fibrin gel, compare to bare fibrin gel, the nanoparticle-fibrin gel complex without BMP-2, or the BMP-2 in fibrin gel, in terms of the new bone area and the gray level in X-ray, the bone marrow are, and the calcium content in the initial defect site. These findings suggest that the BMP-2 loaded nanoparticle-fibrin gel complex can a promising candidate for a new bone defect replacement matrix.

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유리 피판술과 동측 비골 전위술을 이용한 경골 결손의 재건 (Reconstruction of Tibia Defect with Free Flap Followed by Ipsilateral Fibular Transposition)

  • 정덕환;박준영;한정수
    • Archives of Reconstructive Microsurgery
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    • 제14권1호
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    • pp.42-49
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    • 2005
  • Between June 1989 and may 2004 Ipsilateral vascularized fibular transposition was performed on nine patients with segmental tibial defects combined with infection following trauma. Ipsilateral vascularized fibular graft was performed on two or three stage according to the degree of infection. Initially free vascular pedicled graft was done followed by ipsilateral vascularized fibular graft. Type of free flap used is scapular free flap 3 cases, latissimus dorsi free flap 5 cases and dorsalis pedis flap 1 cases. The patients were followed for an average of 3.4 years. the average time to union was 6.7 months, and in all patients the graft healed in spite of complication. Complication was free flap venous thrombosis in 1 cases, persistent infection in 1 cases, delayed bony union at the distal end of fibular graft in 2 cases. The results showed that more faster bony union was seen in which cases firmly internally fixated and more faster hypertrophy of graft in which cases was permitted to ambulate on early weight bearing and more faster healing in which cases debrided more meticulously. Reconstruction of tibia defect with free flap followed by Ipsilateral fibular transposition is a useful and safe method to avoid the potential risk of infection for patients with tibial large bone defect and soft tissue defect associated with infection.

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Mobile용 TFT-LCD 화면 검사장비 개발 (Development of the Defect Inspection Equipment for Mobile TFT-LCD Modules)

  • 구영모;황만수
    • 한국지능시스템학회논문지
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    • 제19권2호
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    • pp.259-264
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    • 2009
  • Mobile용 TFT-LCD는 근거리에서, 세밀한 관찰 작업용으로 사용되는 경우가 많아 높은 수준의 품질관리가 요구되고 있으나, 높은 휘도값, 큰 휘도편차, 높은 검사 정밀도 등의 특징을 가지고 있어 동일한 검사기준을 적용하여도 작업자 혹은 제조라인에 따라 판단의 차이가 있으며 정량적인 품질관리가 어렵다. 또한, 다품종 대량생산 추세에 따라 검사 속도, 작업자의 피로도, 검사 시야의 한계 등 육안검사의 문제점이 대두되고 있다. 본 논문은 Mobile용 TFT-LCD 화면의 품질관리 및 검사기준과 동일한 기준에 의거하여 현장에 적용하기 쉬운 탁상형의 Mobile용 TFT-LED 화면 검사 장비를 개발하였다. 그리고 개발된 장비를 사용한 실험에서, 육안검사에 비하여 개선된 결과를 기반으로 안정적이고 수치화된 Mobile용 TFT-LCD 화면 품질 검사의 표준화 가능성을 제시한다.

실적자료에 의한 공동주택 마감공사의 하자보수기간의 적절성 평가 기초연구 (Basic Research on Evaluation of Defect Repair Period of Finishing Works in Apartment Houses according to Performance Data)

  • 김대길;이웅균;서덕석
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2015년도 춘계 학술논문 발표대회
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    • pp.245-246
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    • 2015
  • Cases of lawsuit and conflict are increasing because of defects in apartments in use after the completion of construction. Further, with changes in the consciousness of residents and in the social environment, many residents are showing interest in defect-related lawsuits. However, the term of warranty liability defined in the current law is not practically appropriate, and the verification of the determination of the term of warranty liability is insufficient. Against this background, this research aims to evaluate the appropriateness of defect repair periods by examining the actual defect condition of the finishing work among the various defects related to apartments. Collected performance data are analyzed by statistical techniques by considering the defect occurrence rate per construction type and the construction year of the finishing work in apartment construction. The analysis results will be used as basic data for evaluating the appropriateness of the standards for the term finishing works warranty liability.

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기상환경에 따른 자동차 부품 도장의 불량률 예측 (Prediction of Defect Rate Caused by Meteorological Factors in Automotive Parts Painting)

  • 박상현;문준;황재정
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2021년도 추계학술대회
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    • pp.290-291
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    • 2021
  • 플라스틱 소재 자동차 부품의 도장 공정에서 불량은 다양한 원인과 현상으로 기인하는데, 온도, 습도, 미세먼지 등 기상환경 조건의 변화에 따라 불량률이 변화하는 연관성을 분석하였다. 실제 도장업체에서 1년 동안 수집한 종류별, 원인별 불량률과 기상환경의 상관성을 머신러닝 기법에 의해 학습하고 시험하여 특정의 기상환경에서 불량률을 예측하였다. 그 결과 실먼지로 인한 불량은 98%, 흐름에 대한 불량은 90%의 불량을 예측하여 모델의 성능을 입증하였다.

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총동맥간 잔류증 [IV 형]Rastelli 수술 치험 보고 (Rastelli operation in Persistent Truncus Arteriosus, Type IV: A Case Report)

  • 김형묵
    • Journal of Chest Surgery
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    • 제11권3호
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    • pp.333-341
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    • 1978
  • A 8 year old male was admitted to the Department of Thoracic Surgery, Korea University Hospital on June 22, 1978. The chief complaints were cyanosis and exertional dyspnea since at birth. EKG shows BVH and dextrocardia, phonocardiogram revealed the accentuation of second heart sound in aortic area. Echocardiogram from the left ventricle to the base of the heart, there is a discontinuity between the ventricular septum and the anterior aortic margin with a large aortic root & aortic overriding. His cardiac catheterization data and cardiac angiogram shows situs inversus totalis, dextrocardia, right aortic arch, large ventricular septal defect etc., and finally diagnosed Truncus Arteriosus. Edwards type IV with retrograde aortogram and selective bronchial angiogram. This is the first operative case reported as Rastelli operation for Truncus Arteriosus type IV in the literatures in Korea. Authors have experienced I case of Truncus Arteriosus, Edward type IV and Rastelli operation with Dacron Arterial Conduit Graft under cardiopulmonary bypass on July 3, 1978. The procedures were as follows; 2] Cardiopulmonary bypass: Origin of bronchial arteries excised from descending aorta bilaterally; defects in aorta closed. 2] Horizontal incision made high in right ventricle. 2] Ventricular septal defect [Kirklin type I+II] closed with Teflon patch. 4] Bifurcated dacron arterial graft with pericardial monocusp sutured to the bilateral pulmonary arteries. [Diameter 9 mm: Length 7 cm]. 5] Proximal end of the conduit graft anastomosed to right ventricle. [Diameter 19 mm: Length 5 cm]..Total perfusion time was 220 min. The result of operation was poor due to anastomotic leakage and increased pulmonary vascular resistance resulting acute right heart failure. The patient was died on the operation table. Literatures were briefly reviewed.

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심실 중격 결손증 수술 치험 182례에 대한 임상적 고찰 (Analysis of 182 cases of the ventricular septal defect)

  • 김철훈
    • Journal of Chest Surgery
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    • 제23권5호
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    • pp.871-880
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    • 1990
  • We clinically evaluated 182 cases of the ventricular septal defect that we experienced at the Department of Thoracic and Cardiovascular Surgery, Maryknoll Hospital from March 1986 through June 1990. Of the 182 cases, 95 patients were male and 87 patients were female. Their age distribution ranged from 8 month to 37 years and their mean age was 8.1 years. The most common chief complaint was frequent upper respiratory infection. Among them, 46 patients had associated cardiac anomalies, which were subdivided as follow; 9 cases of patent foramen ovale, 8 cases of infundibular stenosis, 6 cases of pulmonary valvular stenosis, 4 cases of left superior vena cava, and etc. The most common preoperative abnormal EKG finding was left ventricular hypertrophy in 22 cases. Ninety-three patients[51.1%] underwent simple closure of the VSD and the rest[48.0%] underwent patch closure. In anatomical classification by Kirklin type I constituted 24.2%; type II, 74.8%, type III, 0.7%, and the mixed type of type I and II, 0.5%, The important postoperative EKG changes were noted in 38 cases[20.9%], 18 cases of which were incomplete right bundle branch block. Thirty-three patients[18.1%] developed minor and major complications, and five patients died, overall operative mortality being 2.7%.

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남매에서 가족력을 가진 galactosialidosis 1례 (Galactosialidosis with a Family History in a Sibling)

  • 임선주;남상욱
    • 대한유전성대사질환학회지
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    • 제6권1호
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    • pp.32-39
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    • 2006
  • 저자들은 출생 후 정상적인 발달을 보이다가 생후 6개월부터 의식과 운동 발달의 퇴행을 보이던 13개월 환아에서 효소 검사를 시행하여 ${\beta}$-galactosidase의 결핍을 확인하고 $GM_1$-gangliosidosis type 1으로 진단하였지만, 후에 추가적으로 시행한 효소 검사에서 ${\alpha}$-neuraminidase의 결핍도 발견되어 galactosialidosis로 진단한 증례를 경험하였기에 문헌 고찰과 함께 보고하고자 한다.

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대동맥판 폐쇄부전이 동반된 심실중격 결손증 수술 치험 24례 보 (Ventricular septal defect associated with aortic regurgitation: a report of 24 cases)

  • 정경영
    • Journal of Chest Surgery
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    • 제16권4호
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    • pp.476-484
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    • 1983
  • Ventricular septal defect[VSD] associated with aortic regurgitation[AR] represents 2 to 7.5% of all VSD which is most common congenital heart disease. The aortic valve may by normal in infants with VSD, but the aortic regurgitation may be developed in these patients later. The aortic valve became fibrotic, thickened, deformed and prolapsed, so these late deformities require to be corrected with plication, valvuloplasty or aortic valve replacement [AVR]. There are some controversy between the early repair of VSD alone and the late repair of VSD and aortic valve till now. From December 1971 to August 1983, we had experienced 24 patients of VSD associated with AR which constitute 6.5% of our total patients with VSD. The VSD was subpulmoary [type I] in 14[58.3%], subcristal [type II] in 8[33.3%], atrioventricular canal type[type III] in 1, and combine of type I and II in 1. Patch repair of VSD was made in 15 patients and direct suture of small VSD in 9.14 patients had aortic plication of valvuloplasty and 9 had AVR accompanying VSD repair, and 1 patient had VSD closure alone. The postoperative courses of these patients were uneventful except in some cases. A patient who was undertaken AVR with Starr-Edwards ball valve and VSD closure, died due to left ventricular failure and low cardiac output syndrome. Follow up shows, in 14 patients with aortic plication or valvuloplasty, AR was developed in 9. In 9 AVR, there were two later complications which were paravalvular leakage in one and re-AVR due to subacute bacterial endocarditis in another.

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무지 첨부 절단 환자 재건에서 Moberg Flap과 2족지 수질부 유리피판술의 비교 (Comparison between Moberg Flap and Second Toe Pulp Free Flap for Coverage of Tip Amputation of Thumb)

  • 정강재;기세휘;김진수;이동철;노시영;양재원
    • Archives of Plastic Surgery
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    • 제35권5호
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    • pp.527-532
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    • 2008
  • Purpose: Transverse type or volar oblique type of defect of thumb tip can be covered by Moberg flap or second toe pulp free flap. We compared these two methods in functional result, patients' satisfaction, and sensation, etc. to find a better way to cover the defect of the thumb tip. Methods: From 2003 to 2006, we chose the patients randomly with preoperative pictures. The patients had the defect of the thumb tip which is either transverse or volar oblique type. The 6 patients were treated with Moberg flap and other 6 patients were treated with second toe pulp free flap. We have analyzed the results by 2 point discrimination, side pinching power test, pulp to pulp pinching power test, pain scales (visual analogue scale), satisfaction scales of the patients (functional and aesthetic), the degree of the range of motion, etc. Results: All flaps survived without any complications. In the cases of Moberg flaps, the value of static 2 point discrimination test was 5.6 mm, and the value of moving 2 point discrimination test was 4.8 mm. In the cases of second toe pulp free flaps, the values were 9.6 mm and 9.3 mm. In the cases of Moberg flaps, the value of the Side pinch power test was 6.6 kg, 4.4 kg. In the case of second toe pulp free flaps, the values were 4.8 kg and 2.5 kg. The value of aesthetic satisfaction scale of the patients in Moberg flaps was 5.6, the value of functional satisfaction scale of the patients was 3.6. In cases of second toe pulp free flaps, the values were 5.6 and 3.6. The active range of motion of Interphalangeal joint in the cases of Moberg flaps was 46.6 degree, and the active range of motion of metacarpophalangeal joint was 55 degree, in the cases of second toe pulp free flaps, the values were 36.6 degree and 59 degree. Conclusion: As a result, when the defect of the thumb tip is transverse or volar oblique type, we suggest that the operators choose Moberg flap to cover the defect of the thumb tip.