• Title/Summary/Keyword: dead

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Dead cell phagocytosis and innate immune checkpoint

  • Yoon, Kyoung Wan
    • BMB Reports
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    • v.50 no.10
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    • pp.496-503
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    • 2017
  • The human body loses several billions of cells daily. When cells die in vivo, the corpse of each dead cell is immediately cleared. Specifically, dead cells are efficiently recognized and cleared by multiple types of neighboring phagocytes. Early research on cell death focused more on molecular mechanisms of cell death regulation while the cellular corpses were merely considered cellular debris. However, it has come to light that various biological stimuli following cell death are important for immune regulation. Clearance of normal dead cells occurs silently in immune tolerance. Exogenous or mutated antigens of malignant or infected cells can initiate adaptive immunity, thereby inducing immunogenicity by adjuvant signals. Several pathogens and cancer cells have strategies to limit the adjuvant signals and escape immune surveillance. In this review, we present an overview of the mechanisms of dead cell clearance and its immune regulations.

A Study on Development of SCARA robot Using Fuzzy-Sliding mode control (퍼지-슬라이딩 모드를 이용한 스카라 로보트의 제어에 관한 연구)

  • 고석조;이민철;이만형
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1995.04b
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    • pp.241-245
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    • 1995
  • This paper shows that the proposed fuzzy-sliding mode for SCARA robot control could reduce chattering problemed in sliding mode control and is robust against parameter uncertainties. It was very small quantities of chattering in the fuzzy-sliding mode control conpared with that in sliding mode control with two dead-band. In here, the sliding mode control with two dead-band is the method to reduce some chattering by changing into a continuous variable lower control input gain when a state value in pahase palne converged sithin two dead-band. But, the fuzzy-sliding mode control for more reducing chattering is the method to change control input by slicing mode into that by fuzzy rule within two dead-band. Simulations show that the effect of reducing chattering by the fuzzy-sliding mode is superior to sliding mode control with two dead-band.

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Dead Time Compensation of Vector Controlled Inverter Using Space Vector Modulation Method (공간벡터 전류제어 기법을 이용한 벡터제어형 인버터의 dead time 보상)

  • Hong, Ki-Phil;Oh, Won-Seok;Kim, Young-Tae;Kim, Hee-Jun
    • Proceedings of the KIEE Conference
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    • 1994.07a
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    • pp.265-269
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    • 1994
  • The switching dead time avoiding a bridge leg short circuit in PWM voltage source inverter produces distortions of the controlling inverter output performance such as current waveform, voltage vector, and torque. In this paper, the influence of dead time is investigated. The on-line space voltage vector modulation method is used for current controller. It is possible to compensate dead time by space voltage vector modulation which generates additional pulse compensating voltage distortion caused by dead time. In addition, narrow pulse which is generally neglected can be compensated. All the algorithms, including field-oriented control are performed by one chip microprocessor 80C196MC and DSP TMS320C31. Experimental results probe that the proposed scheme provides a good inverter output performance.

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Current Waveform Improvement of PWM Inverter (PWM 인버터의 전류파형 개선에 관한 연구)

  • 장석주;조상환;설승기
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.39 no.3
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    • pp.273-280
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    • 1990
  • To prevent the shoot-through phenomena in a PWM inverter, a short dead time is usually provided between a pair of switching transistors in the same leg of the inverter. In this approach, the amount of the dead time is designed to meet the worst case condition of the inverter transistors and the base drive elements. So, in normal cases, relatively large portion of the dead time is unnecessary and it results in an undesirablecurrent waveform distortion and generates ripple torque on the motor shaft. In this paper, a new base drive method to remove the undesirable portion of the dead time is described. The method senses the transistor on/off states to interlock the other transistor of the leg without the external dead time. Also, for the transistors of large current rating, the Darlington drive circuit is combined to the proposed method and is tested to verify the effectiveness. The experimental results of the proposed method are described and compared with those of the conventional dead time method.

James Joyce's 'The Dead' Revisited

  • Kim, Donguk
    • Journal of English Language & Literature
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    • v.55 no.3
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    • pp.429-440
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    • 2009
  • This paper does not follow the well-known critical practice of Charles Perke, Edward Brandabur and Phillip Herring who, regarding The Dead, James Joyce s earliest masterpiece, as the conclusion of Dubliners, classify Gabriel as one of the dead. Instead it concurs with such critics as William York Tindal, Kenneth Burke and Allen Tate who, interpreting The Dead as a story of Gabriel s spiritual maturation, discuss the famous snow vision at the end of the story as a signifier of his rebirth experience. A new reading of The Dead, which is the aim of this paper, examines the very processes which produce both form and content, thereby demonstrating that The Dead is a story of Gabriel s spiritual growth and that the supreme snow vision is prepared for his spirit which progresses towards a richer synthesis of life and death, a higher altitude of flight and wider horizons.

The effect of dead coral skeletons on the water quality and sessile mollusks in the closed system (폐쇄시스템 내에서 죽은 산호골격이 수질과 고착성 연체동물에 미치는 영향)

  • Lee, Nam Hyeon;Han, Kyung Nam
    • The Korean Journal of Malacology
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    • v.28 no.3
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    • pp.187-196
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    • 2012
  • Recently, for the purpose of constructing artificial ecosystem, the public aquarium and experimental mesocosm systems are receiving attention. To design and establish an aquarium and mesocosm system, there is need of several materials for simulating the environment, such as sediments, rocks, and plants. Expecially for sessile mollusks, there must be proper materials to which sessile invertebrates can adhere. Nowadays, many aquariums and mesocosm systems are using dead coral skeletons for sessile mollusks. This study was proceeded to have data on the effect of dead coral skeletons on water qualities with the experiment on the environmental factors. For this purpose, I made glass tank for experiment, chose two types of dead coral skeletons imported from the Indonesia and observed the change of water qualities and decomposition efficiency of TAN (total ammonia-nitrogen), nitrite ($NO_2{^-}$) and nitrate ($NO_3{^-}$). As a result, the lager the surface area was, the more TAN, nitrite and nitrate decomposition rate increased. In addition, coral skeletons covered with crustose algae and bacteria in the tank showed faster TAN, nitrite and nitrate removal rate and stabilization. Accordingly, this experiment suggested that dead coral skeletons could be used as a sub filter for the closed system as well as an adhering plate.

PWM CMOS DC-DC Boost Converter with Adaptive Dead-Time Control (Dead-Time 적응제어 기능을 갖는 PWM CMOS DC-DC 부스트 변환기)

  • Hwang, In-Ho;Yoon, Eun-Jung;Park, Jong-Tae;Yu, Chong-Gun
    • Journal of IKEEE
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    • v.16 no.3
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    • pp.203-210
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    • 2012
  • Since the non-overlapping gate driver used in conventional DC-DC boost converters generates fixed dead-times, the converters suffer from the body-diode conduction loss or the charge-sharing loss. To reduce the efficiency degradation due to these losses, this paper presents a PWM DC-DC boost converter with adaptive dead-time control. The proposed DC-DC boost converter delivering 3.3V output from a 2.5V input is designed with CMOS $0.3{\mu}m$ technology. It operates at 500kHz and has a maximum power efficiency of 97.3%.

Dead Time Compensation Algorithm for the 3-phase Inverter (3상 인버터에 대한 간단한 데드타임 보상 알고리즘)

  • Kim, Hong Min;Baek, Seung Ho;Ahn, Jin Woo;Lee, Dong Hee
    • Proceedings of the KIPE Conference
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    • 2011.11a
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    • pp.71-72
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    • 2011
  • This paper presents a novel and direct dead time compensation method of the 3 phase inverter using space vector pulse width modulation(SVPWM) topology. In the turn on time calculation of the effective voltage, the dead time effect is directly compensated according to the current direction of the midium voltage reference. Since the turn on time of the effective voltage vector is affected by the dead time, the loss time is compensated to turn on time of the effective voltage vector. And the dead time is added to the calculated voltage vector switching times according to the current direction. For the more effective compensation, the direction of the midium phase current is considered by the practical direction and voltage drops in the power devices. The proposed method can compensate the dead time which is considered feedback error or direction of middle phase current without coordinate transform in added controller. The proposed dead time compensation scheme is verified by the computer simulation and experiments of 3 phase R L load.

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A Study on the Risk of Occupational Infectious Disease of Police Scientific Investigator (The Bacterial Culture of the Putrefying Dead Body Specimen)

  • Lim, Chae-Won;Kim, Jin-Gak
    • Korean Journal of Clinical Laboratory Science
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    • v.45 no.4
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    • pp.154-158
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    • 2013
  • The unnatural dead body refers to a corpse which is suspicious of unusual death and the dead case has been occurred more than 20 thousands times every year during the recent five years and most of them are found decayed. Police Scientific Investigators investigate unnatural dead bodies and its surroundings in all-around way and determine whether the death is involved with a crime, and most of the Scientific Investigators are exposed to a danger to get infected with pathogenic bacteria which are generated during the decaying process of dead body and are mostly to cause serious injuries on human beings. In line with the fact, the present study conducted a bacterial analysis by collecting excretions from 60 dead bodies and culturing the bacteria to evaluate infection risk of the police agents. The study cultured bacteria from 60 bodies and classified pathogenic bacteria of 108 strains, and its main bacteria are found to be them (; Acinetobacter baumannii 20 strains (19%), Pseudomonas aeruginosa 19 strains (18%), E. coli 18 strains (17%), Klebsiella pneumoniae 11 strains (10%), Proteus mirabillis 10 strains (9%), Enterococcus faecium 10 strains (9%), Staphylococcus aureus 9 strains (8%), Bacillus spp. 5 strains (5%), Streptococcus pneumoniae 3 strains (3%), Candida albicans 2 strains (2%), Mycobacterium tuberculosis 1 strains (1%)). The study results are expected to be used as educational data for preventing the Police Scientific Investigator from infections with bacteria or as a minimum data for improving work environment of the agents.

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Topology Generation and Analysis of the No Dead Time AC/DC Converter

  • Zheng, Xinxin;Xiao, Lan;Tian, Yangtian
    • Journal of Power Electronics
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    • v.14 no.2
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    • pp.249-256
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    • 2014
  • A novel topology generation method for the no dead-time three-phase AC/DC converter is proposed in this study. With this method, a series of no dead time topologies are generated and their operation principles are analyzed. The classic three-phase bridge AC/DC converter can realize a bidirectional operation. However, dead-time should be inserted in the driving signals to avoid the shoot-through problem, which would cause additional harmonics. Compared with the bridge topology, the proposed topologies lack the shoot-through problem. Thus, dead time can be avoided. All of the no dead time three-phase AC/DC converters can realize bidirectional operation. The operating principles of the converters are analyzed in detail, and the corresponding control strategies are discussed. Comparisons of waveform distortion and efficiency among the converters are provided. Finally, 9 KW DSP-based principle prototypes are established and tested. Simulation and experimental results verify the theoretical analysis.