• 대한한의학회지
• /
• 제34권1호
• /
• pp.15-28
• /
• 2013

Objectives: The purpose of this study was to investigate the differences in kind, intensity and depth of de Qi sensation by patients' gender, age, BMI and sensitivity. Methods: Sixty-four healthy volunteers (mean age $26.51{\pm}4.72$, range 22-39) who had been studying anatomy, meridianology, acupuncture & moxibustion for more than five years at Dongguk University, Go-yang, Korea, were invited to take part in an investigation of the sensations associated with acupuncture needling. Needling was self-administered on Hegu (LI4) in the hand and Zusanli (ST36) in the leg randomly. After obtaining de Qi, the participants were asked the kind, intensity and depth of de Qi sensation. Results: There was no statistically significant difference in the kind of de Qi sensation found by acupoints and needling methods (p>0.05). Hegu (LI4) was found to be significantly higher in the intensity (p<0.001), and the depth of de Qi sensation was significantly higher in Zusanli (ST36) than Hegu (LI4) (p<0.001). There was statistically significant difference found in the intensity of de Qi sensation by depth and sensitivity (p<0.05). In the depth of de Qi sensation, there was statistically significant difference found by sensitivity (p<0.05). In de Qi sensation of practitioners, there was statistically significant difference found by gender, BMI, the intensity of de Qi sensation (VAS) and sensitivity. Conclusions: Further study involving acupuncture de Qi sensation and the influencing factors is needed.

• Korean Journal of Acupuncture
• /
• 제24권1호
• /
• pp.43-58
• /
• 2007

Objectives : The elicit of DeQi, a composite of sensation including numbness and fullness that develops at the site of acupuncture stimulation, is considered to be clinically essential to establish treatment efficacy. However, there was little studies investigating the relationship between the subjective feeling of acupuncture sensation and acupuncture analgesia, The current study was therefore performed to determine the correlation between the acupuncture sensation scale (ASS) and the degree of acupuncture analgesia. Methods : Ninety-two female subjects were stimulated at LI4 acupoint on non-dominant hand with real (RA) or sham acupuncture (SA). Finger withdrawal latency (FWL) of each group was also measured to evaluate analgesic effect of acupuncture on the noxious heat stimuli on the dominant hand. All subjects were asked to complete seven point-Likert scale ASS developed by Vincent et al. Results : The increase rate of FWL of the RA group was significantly higher than that of the SA group(36.03 ${\pm}$ 4.45% vs 24.50 ${\pm}$ 3.73%). RA stimulation produced significantly higher rating of all the ASS except for dull sensation, compared to SA stimulation. Significant correlations between analgesic effect of RA, but not of SA, and the degree of the ASS, including burning sensation(r=0.349), Intense sensation(r=0.299), pulsating sensation (r=0.335), and stinging sensation (r=0.306) were found. Conclusions : The results of our study indicate that the DeQi sensation are associated with acupuncture analgesia. Our findings suggest that the evocation of DeQi might be useful clinical indicator of acupuncture treatment.

• Journal of Acupuncture Research
• /
• 제33권3호
• /
• pp.129-144
• /
• 2016

Objectives : This study aims to review the actual use of acupuncture manipulation in clinical trials and to discuss the directions of studies, to be conducted in the future. Methods : Through five search engines, clinical trial papers were collected, which had involved the use of acupuncture treatment since 2001 when STRICTA was published. The selected papers were classified based on whether acupuncture manipulation and De-Qi were stated. The comparison status of domestic and foreign, status by year, target diseases, and therapeutic interventions were also investigated. Results : 54 % domestic and 69 % foreign papers mentioned acupuncture manipulation or De-Qi. Among them, acupuncture manipulation was used in 40 % domestic and 53 % foreign papers. There was no significant difference around 2010 when the revised edition of STRICTA was published. The use of acupuncture manipulation was the highest in studies that targeted musculoskeletal disorders. Besides that, the use of acupuncture manipulation was higher in cases where acupuncture was used for therapeutic interventions than it was for basic manipulation or combination therapy. Conclusion : Compared to the importance of acupuncture manipulation and De-Qi, there was actually a smaller number of papers that clearly suggested information on acupuncture manipulation and De-Qi. The reason is considered to be a lack of studies to establish the mechanism and effectiveness of each acupuncture manipulation method and studies that objectified the amount of stimulation incurred by the acupuncture manipulation methods. It is necessary to properly utilize acupuncture manipulation by actively conducting these studies.

• 대한한의학회지
• /
• 제28권2호통권70호
• /
• pp.66-79
• /
• 2007

Objectives : To explore the type and frequency of short term reactions, de Qi associated with acupuncture treatment and to determine the incidence of adverse events following acupuncture in Korea. Subjects and methods : This study is a retrospective and cross-sectional survey of patient reports. 1095 subjects, 585 of out-patients of the Oriental Medicine of Stroke & Neurological Disorders Center, East-West NEO Medical Center of Kyunghee University and 510 of out-patients of the Department of Cardiovascular & Neurologic Diseases (Stoke Center), Hospital of Oriental Medicine, Kyunghee Medical Center, from June through November of 2006, who had acupuncture, gave informed consent and completed one survey form. On this form, patients were asked to report short term acupuncture reactions, de Qi, patient satisfaction measurement (using VAS), and adverse events relating to acupuncture treatment. The acupuncturists of this study are Korean Medicine Doctors (KMD) who had worked as practitioners for 3-30 years or more. Results : The average age of the 1095 subjects was 58 years old. Positive short term acupuncture reactions after treatment were reported by 878 (80.2%), negative short term acupuncture reactions by 75 (6.8%) and no reactions were reported by 142 (13.0%). The most common positive short term acupuncture reactions were feeling 'relaxed', 472 (43.1%), followed by feeling 'less pain' 90 (8.2%), 'energized' 16 ( 1.5%), 'tingling' 16 (1.5%), 'heat feeling or Cold feeling' 10 (0.9%), and others 274 (25.0%), respectively. Negative short term acupuncture reactions were feeling 'pain' 37 (3.4%), tiredness 24 (2.2%), dizziness 9 (0.8%), and others 5 (0.2%), respectively. Traditionally described needling sensations of de Qi refer to a patient's response to distention, pulling, soreness, heaviness, numbness. 39.7% of subjects reported de Qi during needling, experiencing 'distention' 333 (30.4%), 'soreness' 52 (4.7%), 'pulling' 22 (2.0%), 'heaviness' 18 (1.6%), and 'numbness' 10 (0.9%) respectively. Positive short term acupuncture reactions and de Qi rate were the highest in the less than 40 years group (83/96 86.5%, 50/96 52.1%). No acupuncture reactions were highly seen in the over 70 years old group (31/187, 16.6%). Patient satisfaction level using VAS was a comparatively high $72.9{\pm}19.9$. Adverse events were only bleeding in 92 (8.4%) of the total subjects. High sensitive acupoints were 95 points as GV26 (54 times), LI4 (54 times), ST36 (53 times), GB20 (37 times), HT8(34 times), LV3 (29 times), SI3 (29 times), and LI11 (27 times) in order. Main impressions were stroke patients 430 (16.9%), headache 185 (16.9%), hypertension 97 (8.9%), and dizziness 85 (7.8%). Conclusions : Although 8 different Korean Medicine Doctors participated in this research, we obtained similar results from each. There were no significantly different results between the two hospitals. Short term acupuncture reactions and de Qi were most related to age. Except for bleeding there were no adverse events relating to acupuncture treatment in this study. We consider acupuncture treatment as very safe depending on practitioners. Positive short term acupuncture reactions after treatment were 12 times higher than negative short term acupuncture reactions. Subjects were comparatively satisfied with acupuncture treatment.

• Asian-Australasian Journal of Animal Sciences
• /
• 제26권5호
• /
• pp.609-624
• /
• 2013

The objective of this study was to get a comprehensive understanding of how genes in chicken shell gland modulate eggshell strength at the early stage of active calcification. Four 32-week old of purebred Xianju hens with consistent high or low shell breakage strength were grouped into two pairs. Using Affymetrix Chicken Array, a whole-transcriptome analysis was performed on hen's shell gland at 9 h post oviposition. Gene ontology enrichment analysis for differentially expressed (DE) transcripts was performed using the web-based GOEAST, and the validation of DE-transcripts was tested by qRT-PCR. 1,195 DE-transcripts, corresponding to 941 unique genes were identified in hens with strong eggshell compared to weak shell hens. According to gene ontology annotations, there are 77 DE-transcripts encoding ion transporters and secreted extracellular matrix proteins, and at least 26 DE-transcripts related to carbohydrate metabolism or post-translation glycosylation modification; furthermore, there are 88 signaling DE-transcripts. GO term enrichment analysis suggests that some DE-transcripts mediate reproductive hormones or neurotransmitters to affect eggshell quality through a complex suite of biophysical processes. These results reveal some candidate genes involved with eggshell strength at the early stage of active calcification which may facilitate our understanding of regulating mechanisms of eggshell quality.

• Advances in aircraft and spacecraft science
• /
• 제5권6호
• /
• pp.633-652
• /
• 2018

The present paper focuses on the development of a model for simulating the thermoelectric behavior of CNTs/CFRP Organic Matrix Composite (OMC) laminates for aeronautical applications. The model is developed within the framework of the thermodynamics of irreversible processes and implemented into commercial ABAQUS Finite Element software and validated by comparison with experimental thermoelectric tests on two types of composites materials, namely Type A with Carbon Nanotubes (CNT) and Type B without CNT. A simplified model, neglecting heat conduction, is also developed for simplifying the identification process. The model is then applied for FEM numerical simulation of the thermoelectric response of aircraft panel structures subjected to electrical loads, in order to discuss the potential danger coming from electrical solicitations. The structural simulations are performed on quasi-isotropic stacking sequences (QI) $[45/-45/90/0]_s$ using composite materials of type A and type B and compared with those obtained on plates made of metallic material (aluminum). For both tested cases-transit of electric current of intermediate intensity (9A) and electrical loading on panels made of composite material-higher heating intensity is observed in composites materials with respect to the corresponding metallic ones.

• Kyungpook Mathematical Journal
• /
• 제51권4호
• /
• pp.375-384
• /
• 2011

We study Baer and quasi-Baer modules over some classes of rings. We also introduce a new class of modules called AI-modules, in which the kernel of every nonzero endomorphism is contained in a proper direct summand. The main results obtained here are: (1) A module is Baer iff it is an AI-module and has SSIP. (2) For a perfect ring R, the direct sum of Baer modules is Baer iff R is primary decomposable. (3) Every injective R-module is quasi-Baer iff R is a QI-ring.

• 정보보호학회논문지
• /
• 제25권3호
• /
• pp.493-500
• /
• 2015

정부 3.0 공공정보 공유 및 개방, 소셜네트워크서비스의 활성화 그리고 사용자 간의 공유 데이터 증가로 인터넷상에 노출되는 사용자의 개인 정보가 증가하고 있다. 이에 따라 프라이버시를 지키기 위한 익명화 알고리즘이 등장하였으며 관계형 데이터베이스에서의 익명화 알고리즘은 k-익명성(k-anonymity)을 시작으로 ${\ell}$-다양성(${\ell}$-diversity), t-밀집성(t-closeness)으로 발전하였다. 익명화 알고리즘의 성능 향상 부분은 계속해서 효율적인 방법이 제안되고 있지만, 기업이나 공공기관에서는 알고리즘 성능의 향상보다는 전체적인 익명화 처리 방법이 필요한 실정이다. 본 논문에서는 관계형 데이터베이스에서 데이터의 그룹화를 이용하여 k-익명성, ${\ell}$-다양성, t-밀집성 알고리즘을 처리하는 과정을 구체화하였다.

• Korean Journal of Acupuncture
• /
• 제23권4호
• /
• pp.85-99
• /
• 2006

Objectives : Proper acupuncture stimulation is associated with a characteristic set of sensation usually referred to as 'De-Qi'. In order to develop the appropriate sham acupuncture, various sensations to each stimulation should be considered through analysis of the profiles of acupuncture sensation. It was therefore investigated to compare the acupuncture sensation scale (ASS) of two types of sham acupuncture to that of the real acupuncture. Methods : Ninety-four participants (mean age 26.4, range 26-49) were asked to complete five point-Likert scale ASS developed by Vincent et al. after real or two-kinds of sham acupuncture stimulation: blunted tip sham acupuncture (BT) and round tip sham acupuncture (RT). Needling was done at LI4 acupoint on non-dominant hand and stimulated for 30 seconds with real or two-kinds of sham needle. Finger withdrawal latency (FWL) of each group was also measured to evaluate the pain sensitivity to noxious heat stimuli. Results : BT acupuncture significantly less produced penetrating, numb, intense, hurting, pulling, shock, tingling, throbbing sensation than real acupuncture stimulation. RT acupuncture significantly less produced penetrating, burning, electric, numb, intense, hurting, pulling, aching, shasharp, shock, stinging, tingling, throbbing sensation than real acupuncture. Each group did not demonstrate the differences of pain sensitivity to noxious stimuli. Conclusions : These results indicated that types of tip of acupuncture produced different kinds of acupuncture sensation. Our finding provides a general information of sensations to two kinds of sham acupuncture for development of ideal placebo sham needle.

• 동의생리병리학회지
• /
• 제29권4호
• /
• pp.281-288
• /
• 2015

This paper researches the features of blood stasis theory of Wangqingren, who wrote 『Yilingaicuo』 that greatly contributed in the development of blood stasis theory at Qing dynasty period. And the disease cause, disease mechanism of blood stasis and scope of modern diseases related with blood stasis are studied by research on clinical papers which used 33 prescriptions in 『Yilingaicuo』 in modern times. Research on the features of blood stasis theory of Wangqingren is proceeded by referring to the annotations of 『Yilingaicuopingyi』 and the papers which related with blood stasis from Korea and China. And clinical papers are searched in China Academic Journals(CAJ) of China National Knowledge Infrastructure(CNKI) to analyse the scope of modern diseases related with blood stasis. The features of blood stasis theory in 『Yilingaicuo』 expanded the range of existing theory. Wangqingren thought that chronic disease, weird disease, the disease of no effect from normal treatments were related with blood stasis. And he attached great importance to qi and blood and thought that the main pathogenesis of blood stasis was qi deficiency. And a lot of Astragalus membranaceus Bunge were combined in many prescriptions to reinforce qi. He also used different herbs according to the location of the disease. Musk and Allium fistulosum were used for the disease located at head or upper part of the patient's trunk. Bupleurum falcatum L., Aurantii Fructus Pericarpium and Platycodon grandiflorum A. De Candolle were used for the disease located at thorax. Cyperus rotundus L., Linderae Radix and Aurantii Fructus Pericarpium were used for the disease located at the stomach or below the costal angle. Foeniculi Fructus and Corydalis remota were used for the disease located at belly or lower part of the patient's trunk. Trogopterorum Faeces, myrrha, Cyperus rotundus L. and Cnidium officinale were used for the disease located at extremity or joint.