• Asian-Australasian Journal of Animal Sciences
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• 제30권11호
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• pp.1550-1556
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• 2017

Objective: This study estimated the genetic parameters for productive and reproductive traits. Methods: The data included production and reproduction records of animals that have calved between 1979 and 2013. The genetic parameters were estimated using multivariate mixed models (DMU) package, fitting univariate and multivariate mixed models with average information restricted maximum likelihood algorithm. Results: The estimates of heritability for milk production traits from the first three lactation records were $0.03{\pm}0.03$ for lactation length (LL), $0.17{\pm}0.04$ for lactation milk yield (LMY), and $0.15{\pm}0.04$ for 305 days milk yield (305-d MY). For reproductive traits the heritability estimates were, $0.09{\pm}0.03$ for days open (DO), $0.11{\pm}0.04$ for calving interval (CI), and $0.47{\pm}0.06$ for age at first calving (AFC). The repeatability estimates for production traits were $0.12{\pm}0.02$, for LL, $0.39{\pm}0.02$ for LMY, and $0.25{\pm}0.02$ for 305-d MY. For reproductive traits the estimates of repeatability were $0.19{\pm}0.02$ for DO, and to $0.23{\pm}0.02$ for CI. The phenotypic correlations between production and reproduction traits ranged from $0.08{\pm}0.04$ for LL and AFC to $0.42{\pm}0.02$ for LL and DO. The genetic correlation among production traits were generally high (>0.7) and between reproductive traits the estimates ranged from $0.06{\pm}0.13$ for AFC and DO to $0.99{\pm}0.01$ between CI and DO. Genetic correlations of productive traits with reproductive traits were ranged from -0.02 to 0.99. Conclusion: The high heritability estimates observed for AFC indicated that reasonable genetic improvement for this trait might be possible through selection. The $h^2$ and r estimates for reproductive traits were slightly different from single versus multi-trait analyses of reproductive traits with production traits. As single-trait method is biased due to selection on milk yield, a multi-trait evaluation of fertility with milk yield is recommended.

• Asian Pacific Journal of Cancer Prevention
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• 제15권24호
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• pp.10577-10583
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• 2015

Background: Triple-negative breast cancer (TNBC), characterized by the lack of expression of estrogen receptor, progesterone receptor and human epidermal growth factor receptor-2, is typically associated with a poor prognosis. The majority of TNBCs show the expression of basal markers on gene expression profiling and most authors accept TNBC as basal-like (BL) breast cancer. However, a smaller fraction lacks a BL phenotype despite being TNBC. The literature is silent on non-basal-like (NBL) type of TNBC. The present study was aimed at defining behavioral differences between BL and NBL phenotypes. Objectives: i) Identify the TNBCs and categorize them into BL and NBL breast cancer. ii) Examine the behavioral differences between two subtypes. iii) Observe the pattern of treatment failure among TNBCs. Materials and Methods: All TNBC cases during January 2009-December 2010 were retrieved. The subjects fitting the inclusion criteria of study were differentiated into BL and NBL phenotypes using surrogate immunohistochemistry with three basal markers $34{\beta}E12$, c-Kit and EGFR as per the algorithm defined by Nielsen et al. The detailed data of subjects were collated from clinical records. The comparison of clinicopathological features between two subgroups was done using statistical analyses. The pattern of treatment failure along with its association with prognostic factors was assessed. Results: TNBC constituted 18% of breast cancer cases considered in the study. The BL and NBL subtypes accounted for 81% and 19% respectively of the TNBC group. No statistically significant association was seen between prognostic parameters and two phenotypes. Among patients with treatment failure, 19% were with BL and 15% were with NBL phenotype. The mean disease free survival (DFS) in groups BL and NBL was 30.0 and 37.9 months respectively, while mean overall survival (OS) was 31.93 and 38.5 months respectively. Treatment failure was significantly associated with stage (p=.023) among prognostic factors. Conclusions: Disease stage at presentation is an important prognostic factor influencing the treatment failure and survival among TNBCs. Increasing tumor size is related to lymph node positivity. BL tumors have a more aggressive clinical course than that of NBL as shown by shorter DFS and OS, despite having no statistically significant difference between prognostic parameters. New therapeutic alternatives should be explored for patients with this subtype of breast cancer.

• 대한정형도수물리치료학회지
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• 제5권1호
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• pp.75-80
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• 1999

The Taekwondo being a martial sports, there are higher chances for the injury to occur than the non martial sports. Therefore, this study analyze the frequency, the area, the type, and the condition of the injury which are prone to occur in the Taekwondo matches; it is to help the Taekwondo players in prevention of the injury and in treatment. The subjects of this study were the 48 players (male 24, female 24) who participated in the final selection contest of the national team player on March 9 to 12, 1993. The data of the injury were obtained from the medical recoder staff and were analyzed to the frequency of the injury per match, the vulnerable area of the injury, the type of injury, and the condition of the injury with a gender difference. There were 24 matches for the male and 24 matches for the female, total 48 matches. Therefore, the total participation number of the players are the double of the match number. 1. The frequency of the injury per match was 18.3%(11/60) for male and 23.1%(12/52) for women. 2. The areas of the injury were ankle 36.4%(4), foot 18.2%(2), knee 18.2%(2), lower leg 18.2%(2), wrist 9.1%(1) in male; foot 33.4%(4), ankle 16.7%(2), knee 16.7%(2), lower back 16.7%(2), lower leg 8.3%(1), face 8.3%(1) in female. 3. The types of the injury were contusion 45.5%(5), sprain 27.3%(3), abrasion 9.1%(1), laceration 9.1%(1), tendon rupture 9.1%(1) in male; contusion 33.3%(4), sprain 33.3%(4), abrasion 16.7%(2), subcutaneous hemorrhage 8.3%(1), dislocation 8.3%(1) in female. 4. The condition of the injury were the unblocked attack 36.4%(4), attacking kick 27.3%(3), blocking a kick 18.2%(2), attacking punch 9.1%, impact with surface 9.1%(1) in male; attacking kick 33.3%(4), unblocked attack 25%(3), blocking a kick 25%(3), attacking punch 8.3%(1), impact with surface 8.3%(1) in female. This study shows that the injury from the Taekwondo matches occurred most in the lower extremity joints and the foot, and shows that the most of the injury types were contusion and sprain. Therefore, it is believed to be helpful to wear the proper fitting ankle or the knee protector and using other protective equipment to prevent the sports injury in the Taekwondo matches.

• 한국수자원학회논문집
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• 제31권1호
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• pp.3-12
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• 1998

호우의 강우강도는 홍수 수문곡선의 첨두유량이나 도달시간에 영향을 미치는 주요 인자이므로 그 영향을 강우-유출 모형의 매개변수나 모형의 지배방정식에 반영하는 것이 합리적이다. 본 논문에서는강우강도의 변호를 탱크모형 최상단 탱크의 유출공 승수 변화에 반영하는 방안을 연구하였다. 탱크의 구조는 표준4단 탱크에서 최상단 유출공의 승수를 같도록 하고 1,2단 탱크의 유출에 지체시간을 부여한 수정형태이다. 내린천 유역의 여러 홍수에 대하여 최상단 탱크의 유출공 승수와 강우강도의 관계를 분석한 결과 강우강도가 증가할 때 승수 a1도 증가하는 경향이 있으나 그 정도는 다소 약하였다.이 경향을 a1=kI$(I:강우강도,k,m:계수)의 근사식으로 작성하여 모형 검증에 사용하였다. 이때 평균강우강도 I(t)는 시각 t에서 몇 시간 전까지의 이동평균을 사용하고, 계산된 a1이 그 전 값보다 크면 a1의 a1을 갱신하여 처음부터 시각 t까지의 강우량으로 다시 유출을 모의하였다. 검증 결과 강우강도를 반영한 유출공 승수 a1의 적용이 고정된 값의 사용에 비하여 홍수모의 오차를 크게 축소할 수 있었다.

• 한국축산식품학회지
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• 제28권2호
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• pp.187-195
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• 2008

The purpose of this study was to establish proper shipping weight and backfat thickness by applying the growth model to backfat thickness, measured by means of not only body weight, but also ultrasonography, and predicting the changes by age. Three breeds, i.e. Duroc, Landrace, and Yorkshie, were analyzed, and the Gompertz, logistic, and Von Bertalanffy model were used for inference with the parameter of the growth model being sex. As a result, both body weight and backfat thickness showed different growth curve parameters and characteristics at inflection points depending on model selection and sex. As for backfat thickness, in estimating the inflection point, unlike the case of body weight, the inflection ages of the boars of the Duroc breed was earlier than that of sows, whereas the inflection ages of the sows of the Landrace and Yorkshire breeds was earlier than that of boars. More than anything else, in the analysis of the changes in backfat thickness according to body weight, as the body weight reached 145kg, the backfat thickness showed much variation as great as 1.7-3.2 cm in each breed and sex. In addition, unlike the other breeds, the boars of the Landrace breed showed an exponential type of relationship between body weight and backfat thickness. As they grow to become 100 kg or heavier, abrupt change in back fat thickness was confirmed. If the growth of body weight and backfat thickness is understood and the genetic relationship is taken advantage of like this, it would be possible to set desired body weight and backfat thickness, and thus help effectively set the shipping time. If not only the phenotype, but also genetic parameters about growth characteristics are estimated and analyzed additionally, more effective data can be generated.

• 자원ㆍ환경경제연구
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• 제23권2호
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• pp.187-224
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• 2014

본 연구에서는 담합의 경제분석에서 고려해야 할 쟁점들을 논의한 후, 이러한 쟁점들을 반영한 방법론을 특정 수송용 연료시장의 분석에 적용하였다. 가상 경쟁가격과 과잉징수를 산정하는 5가지 방법 중 표준시장비교방법에 기반한 회귀분석방법이 최선이다. 수송용 연료시장에서와 같이 국제가격과 환율이 국내가격에 영향을 미치는 제품의 실거래가격을 분석하는 경우 논리에 부합하면서 유연한 함수형태는 로그-로그 함수형태이다. 경제분석의 대상이 되는 자료가 시계열자료인 경우에 ARDL 모형을 시장별 회귀분석모형의 근간으로 채택하는 것이 필요하며, 표준시장비교방법에 기반한 회귀분석방법에서는 구성 회귀식 간에 모수제약이 포함된 ARDL 회귀식 체계를 구축하고 system FGLS로 추정하여야 한다. Friedman 동질성 검정을 통하여 표준시장 여부를 판별할 수 있다. 통계적 유의성은 불확실성 하에서 입증하고자 하는 명제를 확립하는데 요구되는 최소의 요건이다. 담합관련 소송의 경제분석에서는 민감도 분석은 그다지 유용성이 없으며, 최적모형 선별과정이 더 중요한 절차이다. 위 방법론을 특정 수송용 연료시장의 분석에 적용한 결과, 해당 시장에서는 담합에 기인하는 손해액이 없다는 귀무가설을 기각할 수 없었다.

• 자원환경지질
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• 제18권4호
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• pp.309-320
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• 1985

한반도 남한 지역의 지각구조를 연구하기 위하여 USAMSFE(1961~1962) 중력자료를 분석하였다. 이들 중력측정치를 IGSN 71중력치로 환산하기 위하여 -14.7mgal 보정을 실시하였으며, 중력이상의 계산에서는 GRS 67식을 사용하였다. 자료처리과정에 있어서는 polynomial fitting을 이용하여 지역중력이상과 잔류중력이상을 분리하였고, 지각의 평균두께와 지각기저면의 깊이분포를 구하기 위해 FFT(Fast Fourier Transform)를 이용한 power spectrumqnstjr과 하향연속을 실시하였다. 하향연속을 위한 필터링 과정에서 고주파수차단 필터링과 동시에 자료간의 간격을 넓히는 효과를 낼 수 있는 2차원에서의 high-cut filtering and resampling법을 개발적용하였다. 분석의 결과로는 (1) 부우게 이상이 대체로 이 지역의 지체구조선의 방향과 같은 NE-SW방향의 분포를 보이고 있으며, (2) 지각의 평균두께는 약 32km로 나타났고, (3) 지각기저면의 깊이분포는 26km~36km의 범위로서 지표면의 광역적인 지형고도를 반영하고 있으며, 동해안의 지각이 서해안보다 더 얕은 것으로 나타났다. (4) 지각평형정도를 지시해주는 측정점의 고도와 중력이상 사이의 선형회귀방정식을 계산해본 결과, 우리 나라의 지각은 다소 보상이 덜되어 있는 것으로 나타났다.

• 패션비즈니스
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• 제5권2호
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• pp.129-147
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• 2001

The purpose of this study is to survey and analyze domestic fashion education institution's program on apparel prototype and thereupon, address the problems and find their solutions, and thereby, provide for some basic data useful to improve the basic patterns of apparel and ultimately, help reinforce the professional and practical apparel design education. The results of this study can be summarized as follows; 1. 85.1% of the subjects finished graduate or higher courses. Almost all of the college and junior college teachers finished graduate or higher courses, while only 31.6% of those teaching at technical institutes finished graduate or higher courses. Such a finding suggests that colleges tend to employ their faculty members based on their academic background but that technical institutes value the practical ability of their faculty more. 2. As a result of surveying the types of basic patterns used by teachers, it was found that 72.3% of them were using two or more patterns. The basic pattern preferred most by our teachers was Japanese culture institute's type (71.3%), followed by the US FIT type (24.5%), Lim Won-Ja's type (22.3%), French ESMOD type (17.0%). 96.3% of our apparel design students were making their basic patterns as instructed by their teachers. 3. 67.0% of our students were using their conceived sizes for production of their basic patterns, 14.9% were referring to the ready-made sizes, 8.5% were relying on their teachers' individual experiences, and 9.6% were using their own cord sizes. In order to survey the difference between teachers' sizes (ready-made sizes or individual experienced ones) and business sizes used, the basic body measurements used for ready-made apparels were surveyed to be compared with the national standard body sizes set in 1997 for women aged between 18 and 24. As a result, it was found that the ready-made sizes used for apparel production prototypes than teachers' ones were nearer the national standard sizes. Such a finding suggests that it may well be necessary for teachers to be more connected with the apparel businesses and thereby, teach their students in a more realistic way with correct information. 4. 83.0% of the subject teachers were tacking their basic patterns to be well fitting, and 76.9% of these teachers were tacking the patterns in reference with students' individual body sizes. In all, 97.4% of the subject teachers were guiding the tacking process, which suggests that the flat patternmaking is taught primarily for customized apparels. As a result of comparing the fitness of basic patterns with those of each body part, it was found that teachers were most dissatisfied with the fitness of shoulders and arm hole depth. Therefore, it will be necessary to reclassify the body types or find other drawing techniques to improve the fitness of such body parts. Nevertheless, teachers were willing much (4.18) to develop their own educational basic patterns for themselves. Lastly, it is hoped that this study will be followed up by future studies on educational prototypes covering diverse body shapes and those on practical implementations of those prototypes for students.

• Korean Chemical Engineering Research
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• 제53권2호
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• pp.150-155
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• 2015

최근 전세계적인 액화천연가스(LNG) 수요의 증가로 인해 LNG 터미널의 건설이 크게 늘어나고 있으며 기존의 LNG 터미널도 저장시설을 확장하고 있는 추세이다. 이에 따라 LNG 터미널의 다수의 저장탱크가 존재할 때 LNG를 송출하게 될 탱크와 각 송출량을 선택하는 것은 전체 공정 운전에 중대한 영향을 미칠 수 있다. 본 연구에서는 전체 송출량이 정해져 있을 경우 레벨이 각기 다른 탱크들에 대해 발생하는 BOG 양을 최소화 할 수 있도록 각 탱크의 송출량을 최적화하는 연구를 수행하였다. 저장 탱크의 특성과 구조에 맞게 벽면과 바닥면에서 유입되는 열과 탱크 재질의 열전도도를 고려한 동적모델을 구성하였고, 레벨을 변화시켜 각 레벨에 따른 BOG 양을 계산하여 얻은 BOG 발생량을 탱크 레벨에 따라 지수함수로 회귀분석하였다. 이를 통해 탱크의 특성과 레벨에 따라 BOG 발생량을 예측할 수 있는 BOR(Boil-off Rate) 모델을 얻을 수 있었다. 개발한 BOR 모델을 이용하여 BOG 발생량을 최소화하는 목적함수를 설정하고 요구되는 송출량, 탱크내 레벨 제한, 탱크 당 가능한 송출량을 제한조건으로 설정하여 각 탱크의 최적 송출량을 결정하는 운전 최적화를 수행하였다. 이를 실제 운전되고 있는 인천 LNG 터미널의 18개 저장탱크에 적용하여 다양한 레벨이 분포되어 있고 총 송출량이 80,000 m3/day(최대 송출량)이 요구되는 시나리오에 대해 최적화를 수행하여 가정한 기존의 운전방법과 비교하였을 때 BOG 양을 약 9% 감소시킬 수 있었다.

• 한국통신학회논문지
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• 제24권10A호
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• pp.1579-1587
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• 1999

게이트 길이가 $0.2\mu\textrm{m}$인 P-HEMT에 대하여 드레인 바이어스 전류의 변화 및 게이트 폭에 대해 스케일링이 가능한 잡음모델을 제안하였다. 본 논문에서는 S-파라미터를 정확히 예측하기 위하여 $\tau$를 제외한 intrinsic 파라미터는 offset를 도입하여 정규화 한 후 스케일링을 하였다. 드레인 포화전류에 대한 드레인 전류의 비율과 게이트 폭을 변수로 하는 소신호 모델 파라미터의 맞춤함수를 구하였다. 또한, 잡음 파라미터를 정확히 예측하기 위하여 진성저항 잡음 온도 $\textrm{T}_{g}$, 게이트 단 전류 잡음원 등가잡음 컨덕턴스 $\textrm{G}_{ni}$, 드레인 단 전류와 게이트 폭에 거의 관계없으며 이의 평균값은 주변온도와 유사한 값으로 $\textrm{G}_{ni}$는 회로 특성에 영향을 미치지 않을 정도로 작은 값으로 추출되었다. 그러므로, $\textrm{G}_{no}$만을 잡음 모델정수로 하는 잡음모델과 $\textrm{T}_{g}$, $\textrm{G}_{ni}$, $\textrm{G}_{no}$를 잡음 모델정수로 하는 잡음모델을 측정값과 비교하여 본 결과 Gno만을 갖는 잡음모델도 측정된 잡음 파라미터와 잘 일치하였다. 따라서, 모델 정수추출이 간단한 $\textrm{G}_{no}$만을 갖는 잡음모델은 게이트 폭과 바이어스 전류에 대해 스케일링이 가능한 실용적인 잡음모델임을 확인하였다.