• Transactions of the Korean Society of Automotive Engineers
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• v.21 no.3
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• pp.98-104
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• 2013

The effect of the tool-sheet interaction on formability enhancement in electromagnetic forming is investigated using FEM. A free bulging and a conical forming die with 0.7mm AL1050 sheet are used to evaluate damage evolution based on Gurson-Tvergaard-Needleman plasticity material model. The impact between the tool and sheet results in complex stress states including compressive hydrostatic stresses, which leads to a suppression of void growth and restrain ascending void volume fraction of the sheet. Therefore, the damage suppression due to the tool-sheet interaction can be the main factor contributing to the increased formability in the electromagnetic forming process.

• Journal of the Korean Society for Railway
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• v.12 no.1
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• pp.129-134
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• 2009

To ensure the safety and functionality of a railroad bridge, maintaining the integrity of the bridge via continuous structural health monitoring is important. However, most structural integrity monitoring methods proposed to date are based on modal responses which require the extracting process and have limited availability. In this paper, the applicability of the existing damage identification method based on free-vibration reponses to time-domain deflection shapes due to moving train load is investigated. Since the proposed method directly utilizes the time-domain responses of the structure due to the moving vehicles, the extracting process for modal responses can be avoided, and the applicability of structural health evaluation can be enhanced. The feasibility of the presented method is verified via a numerical example of a simple plate girder bridge.

• Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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• 1998.10a
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• pp.67-74
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• 1998

Two kinds of polished and unpolished freestanding films prepared by DC plasma CVD method were impacted by SiC particles to understand erosion mechanism. Erosion damage caused by solid impact was characterized by surface profilometer, scanning electron microscopy and Raman spectroscopy. Gradually decrease of surface roughness and sharp reduction of crystallinity for unpolished CVD films were observed with increasing erosion time. It was found that smaller grains of the diamond were removed in early stage of erosion process and larger grains were eroded with further impingement. By introduction of re-growth method on polished diamond, further understanding of erosion mechanism was achieved. Most of the surface fractures were initiated at the grain boundary.

• Environmental Analysis Health and Toxicology
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• v.18 no.3
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• pp.165-174
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• 2003

Cr (Ⅵ) - containing compounds are well-established carcinogens, although the mechanism for chromium - induced carcinogenesis is still not well understood. The reduction of Cr (Ⅵ) to its lower oxidation states, par ticularly Cr (V) and Cr (IV), is an important step for the production of chromium-mediated reactive oxygen species (ROS). The persistent oxidative stress during the reduction process may play a key role in the mechanism of Cr (Ⅵ) -induced carcinogenesis. This paper summarizes recent studies on (1) the reduction of Cr (Ⅵ) to Cr (III) occur by a multiplicity of mechanisms depending on the nature of reducing agents including ascorbate, diol-and thiol-containing molecules, certain flavoenzymes, cell organelles, intact cells, and whole animals; (2) free-radical production with emphasis on hydroxy radical generation via Fenton or Haber-Weiss type reactions; and (3) free radical - induced cellular damage, such at DNA strand breaks, hydroxylation of 2'-deoxyguanosine, and activation of nuclear transcription factor kB.

• Journal of the Korean Society of Food Science and Nutrition
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• v.26 no.5
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• pp.901-907
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• 1997

The purpose of this study was to investigate the effects of green tea catechin o n free radical generation system and peroxidative damage in the liver of streptozotocin(STZ)-induced diabetic rats. Spragu-Dawley male rats weighing 150$\pm$10gm were randomly assigned to one normal and three STZ-induced diabetic groups; diabetic groups were classified to catechin free diet(DM-oC group), 0.5% catechin diet(DM-0.5C group) and 1% catechin diet(DM-1C group) according to the levels of dietary catechin supplementation. Diabetes was experimentally induced by intravenous injection of 55mg/kg of body wt of STZ in citrate buffer(pH 4.3) after feeding of three experimental diet for 4 weeks. Animals were sacrificed at the 6th day of diabetic states. Activities of serum glutamic oxaloacetic transaminase(GPT) in DM-oC groups were higher than those of the normal group, and those in catechin supplementation group were similar to those of the normal group. Liver lipid peroxide values increased by 153%, 49%, and 27% in Dm-oC, DM-0.5C and DM-0C and Dm-1C but was not significantly different in catechin supplementation groups compared with the normal group, and liver cytochrome $P_{450}$ contents was similar to result of XOD activity. In electron microscopic examination of liver, lysosome was relatively scattered in Dm-oC and Dm-0.5C group and preserved normal shapes in DM-1C group. The present results indicate that STZ-induced diabetic rats are more sensitive to oxidative stress, leading to the acceleration of lipid peroxidation process, but this was reduced by anti-oxidative effect of high level of dietary catechin. It is concluded that dietary catechin serves as powerful antioxidant against lipid peroxidation in diabetic rats.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.20 no.3
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• pp.53-59
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• 2021

In vibration-free vehicles such as limousine buses, the vibration is minimized by installing an air spring instead of the leaf spring used in the existing freight cars to prevent the damage to the loaded cargo from shocks generated during movement. In the existing vehicles, steel structures support the air spring system. This study was aimed at replacing the steel structures used in the Z-spring by carbon fiber and glass fiber reinforced plastics. In addition, the mechanical properties (elastic modulus, tensile strength, and shear strength) of carbon fiber and glass fiber prepreg were derived using specimens molded with the corresponding prepreg. The final goal was to develop a material lighter than the conventional steel material but with enhanced mechanical properties. Although the CF prepreg exhibited excellent mechanical properties, the production cost was extremely high. To overcome this limitation, hybrid composites with GF prepreg were examined, which are expected to be promising future materials.

• Progress in Superconductivity and Cryogenics
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• v.25 no.4
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• pp.28-31
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• 2023

This study presents a comprehensive procedure for the low cycle fatigue test of ultrasonically welded (UW) coated conductor (CC) lap-joints. The entire process is examined in detail, from the robust fabrication of the UW REBCO CC joints to the reliability testing under a low number of repeated cycle fatigue conditions. A continuous I_c measurement system enables real-time monitoring of I_c variations throughout the fatigue tests. The study aims to provide a step-by-step procedure that involves joint fabrication, electromechanical property (EMP) tests under uniaxial tension for stress level determination, and subsequent low-cycle fatigue tests. The joints are fabricated using a hybrid method that combines UW with adding In-Sn soldering, achieving a flux-free hybrid welding approach (UW-HW flux-free). The selected conditions for the low cycle fatigue tests include a stress ratio of R=0.1 and a frequency of 0.02 Hz. The results reveal some insights into the fatigue behavior, irreversible changes, and cumulative damage in the CC joints.

• Structural Engineering and Mechanics
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• v.62 no.5
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• pp.577-585
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• 2017

To study the mechanical performances of prestressed steel-concrete composite box beam under combination of bending-shear-torsion, nine composite beams with different ratio of torsion to bending were designed. Torsion was applied to the free end of the beam with jacks controlled accurately with peripherals, as well as concentrated force on the mid-span with jacks. Based on experimental data and relative theories, mechanical properties of composite beams were analyzed, including torsional angle, deformation and failure patterns. The results showed that under certain ratio of torsion to bending, cracking and ultimate torsion increased and reached to its maximum at the ratio of 2. Three phases of process is also discussed, as well as the conditions of each failure mode.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.9
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• pp.4199-4204
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• 2016

Cancer is a complex disease caused by a progressive accumulation of multiple genetic mutations. Consumption of fruits is associated with lower risk of several cancers, which is mainly associated to their phytochemical content. The use of functional foods and chemopreventive compounds seems to contribute in this process, acting by mechanisms of antioxidant, anti-inflammatory, anti-angiogenic and hormonal. The Psidium Guajava has high potential functional related to pigments who are involved in the process of cancer prevention by having antioxidant activity. The aim of the present review is to expose some chemical compounds from P. Guajava fractions and their association with anti-carcinogenic function. The evidences supports the theory of anticancer properties of P. Guajava, although the mechanisms are still not fully elucidated, but may include scavenging free radicals, regulation of gene expression, modulation of cellular signalling pathways including those involved in DNA damage repair, cell proliferation and apoptosis.

• Toxicological Research
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• v.27 no.1
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• pp.1-6
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• 2011

Lipid peroxidation is a free radical oxidation of polyunsaturated fatty acids such as linoleic acid or arachidonic acid. This process has been related with various pathologies and disease status mainly because of the oxidation products formed during the process. The oxidation products include reactive aldehydes such as malondialdehyde and 4-hydroxynonenal. These reactive aldehydes can form adducts with DNAs and proteins, leading to the alterations in their functions to cause various diseases. This review will provide a short summary on the implication of lipid peroxidation on cancer, atherosclerosis, and neurodegeneration as well as chemical and biochemical mechanisms by which these adducts affect the pathological conditions. In addition, select examples will be presented where antioxidants were used to counteract oxidative damage caused by lipid peroxidation. At the end, isoprostanes are discussed as a gold standard for the assessment of oxidative damages.