• Nuclear Engineering and Technology
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• 제49권5호
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• pp.905-913
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• 2017

Advanced reactor designs often feature longer operating cycles between refueling and new concepts of operation beyond traditional baseload electricity production. Owing to this increased complexity, traditional proportional-integral control may not be sufficient across all potential operating regimes. The prototypical advanced reactor (PAR) design features two independent reactor modules, each connected to a single dedicated steam generator that feeds a common balance of plant for electricity generation and process heat applications. In the current research, the PAR is expected to operate in a load-following manner to produce electricity to meet grid demand over a 24-hour period. Over the operational lifetime of the PAR system, primary and intermediate sodium pumps are expected to degrade in performance. The independent operation of the two reactor modules in the PAR may allow the system to continue operating under degraded pump performance by shifting the power production between reactor modules in order to meet overall load demands. This paper proposes a Takagi-Sugeno (T-S) fuzzy logic-based power distribution system. Two T-S fuzzy power distribution controllers have been designed and tested. Simulation shows that the devised T-S fuzzy controllers provide improved performance over traditional controls during daily load-following operation under different levels of pump degradation.

• 한국농림기상학회지
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• 제21권1호
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• pp.29-41
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• 2019

산림생태계에서 총일차생산성(Gross Primary Production, GPP)은 기후변화에 따른 산림의 생산성과 그에 영향을 미치는 식물계절, 건강성, 탄소 순환 등을 대표하는 지표이다. 총일차생산성을 추정하기 위해서는 에디공분산 타워 자료나 위성영상관측자료를 이용하기도 하고 물리지형적 한계나 기후변화 등을 고려하기 위해 기작기반모델링을 활용하기도 한다. 그러나 총일차생산성을 포함한 산림 탄소 순환의 기작기반 모델링은 식물의 생물, 생리, 화학적 기작들의 반응과 지형, 기후 및 시간 등과 같은 환경 조건들이 복잡하게 얽혀 있어 비선형적이고 유연성이 떨어져 반응에 영향을 주는 조건들을 모두 적용하기가 어렵다. 본 연구에서는 산림 생산성 추정 모델을 에디공분산 자료와 인공위성영상 정보를 사용하여 기계학습 알고리즘을 사용한 모델들로 구축해 보고 그 사용 및 확장 가능성을 검토해 보고자 하였다. 설명변수들로는 에디공분산자료와 인공위성자료에서 나온 대기기상인자들을 사용하였고 검증자료로 에디공분산 타워에서 관측된 총일차생산성을 사용하였다. 산림생산성 추정 모델은 1) 에디공분산 관측 기온($T_{air}$), 태양복사($R_d$), 상대습도(RH), 강수(PPT), 증발산(ET) 자료, 2) MODIS 관측 기온(T), 일사량($R_{sd}$), VPD 자료(개량식생지수 제외), 3) MODIS 관측 기온(T), 일사량($R_{sd}$), VPD, 개량식생지수(EVI) 자료를 사용하는 세 가지 경우로 나누어 구축하여 2006 - 2013년 자료로 훈련시키고 2014, 2015년 자료로 검증하였다. 기계학습 알고리즘은 support vector machine (SVM), random forest (RF), artificial neural network (ANN)를 사용하였고 단순 비교를 위해 고전적 방법인 multiple linear regression model (LM)을 사용하였다. 그 결과, 에디공분산 입력자료로 훈련시킨 모델의 예측력은 피어슨 상관계수 0.89 - 0.92 (MSE = 1.24 - 1.62), MODIS 입력자료로 훈련시킨 모델의 예측력은 개량식생지수 제외된 모델은 0.82 - 0.86 (MSE = 1.99 - 2.45), 개량식생지수가 포함된 모델은 0.92 - 0.93(MSE = 1.00 - 1.24)을 보였다. 이러한 결과는 산림총일차생산성 추정 모델 구축에 있어 MODIS인공위성 영상 정보 기반으로 기계학습 알고리즘을 사용하는 것에 대한 높은 활용가능성을 보여주었다.

• The Korean Journal of Physiology and Pharmacology
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• 제21권1호
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• pp.55-64
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• 2017

Progressive memory impairment such as that associated with depression, stroke, and Alzheimer's disease (AD) can interfere with daily life. In particular, AD, which is a progressive neurodegenerative disorder, prominently features a memory and learning impairment that is related to changes in acetylcholine and abnormal ${\beta}$-amyloid ($A{\beta}$) deposition in the brain. In the present study, we investigated the effects of dehydroevodiamine HCl (DHED) on cognitive improvement and the related mechanism in memory-impaired rat models, namely, a scopolamine-induced amnesia model and a $A{\beta}_{1-42}$-infused model. The cognitive effects of DHED were measured using a water maze test and a passive avoidance test in the memory-impaired rat models. The results demonstrate that DHED (10 mg/kg, p.o.) and Donepezil (1 mg/kg, p.o.) ameliorated the spatial memory impairment in the scopolamine-induced amnestic rats. Moreover, DHED significantly improved learning and memory in the $A{\beta}_{1-42}$-infused rat model. Furthermore, the mechanism of these behavioral effects of DHED was investigated using a cell viability assay, reactive oxygen species (ROS) measurement, and intracellular calcium measurement in primary cortical neurons. DHED reduced neurotoxicity and the production of $A{\beta}$-induced ROS in primary cortical neurons. In addition, similar to the effect of MK801, DHED decreased intracellular calcium levels in primary cortical neurons. Our results suggest that DHED has strong protective effects against cognitive impairments through its antioxidant activity and inhibition of neurotoxicity and intracellular calcium. Thus, DHED may be an important therapeutic agent for memory-impaired symptoms.

• 한국해양학회지:바다
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• 제10권1호
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• pp.8-18
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• 2005

강화도 장화리 펄 조간대 지역에서 2002년 5월-2004년 4월까지 저서미세조류의 계절분포를 조사하였으며, 저서미세조류의 일차생산력 측정과 HPLC를 이용한 색소분석 방법으로 저서미세조류의 생산능력 및 분류군별 분포를 파악하였다. 강화도 갯벌에서 저서미세조류는 조간대 중부에서 많은 현존량을 보였다 강화도 갯벌에서 저서미세조류의 계절별 현존량 변동은 $2.3-140.9{\times}10^5\;cells\;cm^{-2}$의 범위로 하계와 동계에 낮은 현존량을 보였고 2003년 2월에서 4월까지 저서미세조류의 대증식 헌상이 나타났다. 저서미세조류는 대부분 저서성 돌말류가 우점종으로 출현하였고, 특히 연중 Paralia sulcata가 전 정점에서 우점하여 출현하였다. 그외에 Cylindrotheca closterium과 Nitzschia sp.가 2월과춘계에 크게 우점하였다. HPLC 색소분석을 통한 저서미세조류 군집조성은 돌말류를 포함하여 유그레나류, 남조세균, 녹조류, 은편모조류, 황갈조류, 와편모조류 등 다양한 종류가 출현하고 있는 것으로 나타났다. Chl a의 함량은 1.18-34.25 mg $m^{-2}$의 범위로 평균 7.60 mg $m^{-2}$을 보였다. Fuco/Chl a는 평균 0.7로 나타나 연구기간동안 돌말류가 전체 저서미세조류 생물량의 대부분을 차지하고 있음을 보여주었으며 Chl b/Chl a는 평균 0.17로 유그레나류와 녹조류가 일정 시기에 서로 공존하여 서식하는 것으로 나타났다. 평균 일차생산력의 화는 4.2-113.0 mgC $m^{-2}\;hr^{-1}$비 범위로 평균 33.9 mgC $m^{-2}\;hr^{-1}$로 나타났고, 초기기울기 $(\alpha)$의 변화범위는 0.002-0.005$(mgC\;mgchl-a^{-1}\;hr^{-1}){\cdot}({\mu}E\;m^{-2}\;s^{-1})^{-1}$로 측정되었다. 동화계수(Pm)는 0.50-1.32 mgC $mgchl-a^{-1}\;hr^{-1}$의 변화범위를 보였고, 일일 일차생산력은 20.9-678.1 mgC $m^{-2}\;d^{-1}$ 범위로 평균 206.7 mgC $m^{-2}\;d^{-1}$을 보여 일반적인 갯벌에서의 생산력 범위를 보였다.

• 한국물환경학회지
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• 제32권5호
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• pp.433-441
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• 2016

Many large dams have been constructed for water supply, irrigation, flood control and hydropower in Korea for the last century. Meanwhile, recent studies indicated that the artificial reservoirs impounded by these dams are major sources of carbon dioxide (CO₂) to the atmosphere and relevant to global budget of green house gases. However, limited information is available on the seasonal variations of CO₂ evasion from the reservoirs located in the temperate monsoon regions including Korea. The objectives of this study were to estimate daily Net Atmospheric Flux (NAF) of CO₂ in Daecheong Reservoir located in Geum River basin of Korea, and analyze the influencing parameters that characterize the variation of NAF. Daily pH and alkalinity (Alk) data collected in wet year (2012) and dry year (2013) were used for estimating the NAFs in the reservoir. The dissolved inorganic carbon (DIC) was computed using the pH and Alk measurements supposing an equilibrium state among the carbonate species. The results showed seasonal variations of NAF; negative NAFs from May to October when the primary production of the reservoir increased with water temperature increase, while positive NAF for the rest of the period. Overall the reservoir acted as sources of CO₂ to the atmosphere. The estimated NAFs were 2,590 and 771 mg CO₂ m^-2d^-1 in 2012 and 2013, respectively, indicating that the NAFs vary a large extent for different hydrological years. Statistical analysis indicated that the NAFs are negatively correlated to pH, water temperature, and Chl-a concentration of the reservoir.

• 대한지역사회영양학회지
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• 제1권2호
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• pp.250-259
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• 1996

The school foodservice(FS) dietitians of conventional, co-management and central kitchen systems were compared for their levels of fatigue degrees in order to examine their work specification but no to diminish their educational roles. One hundred and thirtheen primary schools in Taejon and Chungcheongnam-Do participated in the survey, of which foodservice were consisted of 99 conventional types, 7 comanagement types and central kitchen types. Information was collected about the various working hours dietary behavior and fatigue symptoms of the dietitians. The results of this study were as follows : Among 3 school foodservice types, dietitians spent 8 hours and 16 minutes daily for their for their work on the average. However, the central kitchen type dietitans in cities spent 3 hours more compared to the others. The data from the dietitians' work schedule sheets showed that the 5 parts of dietitian's duties set in the school foodservice laws were not well performed. In the central kitchen type they spent more time for food production whereas in the conventional they spent more time for menu formation and hygiene control. It was found that fatigue levels of school foodservice dietitians were chronic with no difference among foodservice systems or among school locations. Our results indicated that nutrition education in primary schools was almost neglected. It is suggested that the school foodservice should meet all the objectives of school-lunch program even though they saved dietitians' work load more or less. The importance of students to improve their dietary habits could never be overlooked. (Korean J Community Nutrition 1(2) : 250-259, 1996)

• 디지털융복합연구
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• 제17권10호
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• pp.405-410
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• 2019

본 연구는 도예의 한 분야로서 생칠과 도기가 결합한 형태인 칠도의 공예기법 및 디자인적 융합에 대한 일차적 분석이다. 먼저 칠도의 역사 및 현재의 현황을 제시하고 칠도 장식의 기법을 세 가지로 분류하고 각 기법이 가지는 특징을 간단히 분석하여 제시한다. 칠도는 도자가 가지는 성형 상의 자유로움과 칠예가 도자에 부여하는 표면의 안정성 및 그 표면 장식의 디자인 소재 및 방식의 다양성을 가지고 있어서 일상 용기로서의 실용성 및 예술작품으로서의 미감을 동시에 지니고 있다. 다만 일상용품으로 대량생산하는 데는 어려움이 있어 현재는 예술작품으로서 여러 시도가 이루어지고 있다. 이런 시도를 통해 일반 상품에도 미적 감수성을 높이고 문화적 다양성을 만들 수 있다.

• 한국초지조사료학회지
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• 제4권2호
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• pp.133-139
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• 1983

대관령지역에서 달리함에 따른 韓牛育咸牛의 放牧習性과 生産性을 규명하기 爲하여 Wye大學區, 輪換, 固定, 修正固定, 刈取給與區의 處理를 하였다. 供試面積은 5ha, 공시두수는 육성빈우 20두였으며 放牧習性을 調査하기 爲하여 아침 5:00시부터 20:00시 까지 每 2.5분(2분 30초) 마다 調査하여 얻어진 結果는 다음과 같다. 1. ha당 증체량에 있어서 Wye大學區와 輪換區가 바른 처리구보다 많았으나 山地草地放牧方法으로서 實在로 運用하는데는 윤환구나 修正固定區가 좋았으며 특히 修正固定放牧은 윤환구의 대안으로 추천할 만한 것이었다. 2. 日當增體量은 5월에 가장 높았고 7월에 가장 낮았으며 그후는 차차 증가하는 경향이었다. 3. 晝間의 採食時間은 331.1분으로부터 576.0분으로 다양한 結果를 보였고 이것은 放牧體系에의하여 보다도 秊節, 牧草量의 多少, 그리고 기상에 의하여 영향을 받았다. 4. 한우는 1일 일출 후, 정오 그리고 오후 3時의 3번의 주 채식행동을 갖고 있었다.

• Journal of Chest Surgery
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• 제19권1호
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• pp.35-42
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• 1986

Prevention of thrombombolism after rosthetic cardiac valve replacement is essential for the patients. About 90% of patients are free of major and minor thromboembolic complications 5 year after replacement of cardiac valves with prosthetic devices when they are under control of anticoagulant therapy. Ticlopidine is a drug that alter platelet function to have an antithrombotic effect. It is an antiaggregating agent which inhibits primary platelet function to have an antithrombotic effect. It is an antiaggregating agent which inhibits primary platelet aggregation induced by ADP and increases the production of prostaglandin $D_{2}$. Aspirin in small doses inhibits platelet synthesis of prostaglandins by irreversibly blocking the enzyme cyclo-oxygenase. Platelet secretion and aggregation are impaired with Ticlopidine and Aspirin. the thromboembolic event sof 54 patient s who were treated with Ticlopidine and Aspirin after cardiac valve replacement were evaluated and compared with that of 79 patients who were treated with Wafarin and Aspirin after the same type of operation. The follow-up period ranged from 4 to 110 months (mean of 48 months). there were 11 major thromboembolic episodes including three deaths in the warfarin goup during mean follow-up period of 56 months. two cases of CVA and one hemoarthrosis were noted due to overdose of Warfarin. Inticlopidine group, there was only one fatal thromboembolic epdisode three month after mitral valve replacement during mean follow-up period of 18 months. Two episodes of hypermenorrhea resulting anemia ere noted in the ticlopidine group. We measured the parameters of platelet function in aggreagation curve of platelet with platelet aggregometer (chrono-log Aggregometer, Model No. 430) Aggregation test was performed with three final concentrations of epinephrine in 10 uM/L, ADP in 5uM/L. 28 patients with prosthetic cardiac valves and 35 healthy volunteers were subgrouped as follows to analyze the effect of antithrombotic drugs used. Group I ; 11 patients treated with 250-500 mg of ticlopidine and 0.5gm of Aspirin as a daily single dose after cardiac valve replacement (14 St. Jude Medical and 1 Carpentier-Edwards, 9 patients with atrial fibrillation among them) Group II ; 10 patients treated with 3-5 mg of Warfarin and 0.75 gm of Aspirin daily to prolong prothrombin time around 20 seconds for more than 6 months and single Aspirin dose was maintained afterward as a life-long regimes(3 St. Jude Medical, 1 Hall-Kaster and 7 Carpentier-Edwards valve, 9 patients in atrial fibrilation). Group III ; 7 patients who quit anticoagulant treatment (Warfarin + Aspirin) 6-12 months after the regime as group II (3 St. Jude Medical. 1 bjork-Shiley, 1 Hall-Kaster, 3 Carpentier-Edwards valve, 2 of them are with atrial fibrillation). Group IV ; 35 healthy vounteers (28 males and 7 females). The following results were obtained. 1. The mean maximal platelet aggregability in Group I induced by 10uM/L epinephrine was 15.6%, and 17.5 and 18.7% in BM in proportion to the induction by 5 and 10 uM/L ADP. 2. The mean maximal platelet aggregability in Group II induced by 10uM/L epinephrine was 16.5%, and 27.4 and 44.7% in BM in proportion to the induction by 5 and 10uM/L ADP. 3. The mean maximal platelet aggregability in group III induced by 10uM/L epinephrine was 65%, and 56.5 and 51.8% in BM in proportion to the induction by 5 and 10 uM/L ADP. 4. The mean maximal platelet aggregability in the normal subjects induced by 10 uM/L epinephrine was 64%, and 65 and 69% in Bm inproportion to the induction by 5 and 10 uM/L ADP. 5. Reversible change of platelet aggregation curve induced by 5 and 10uM/L was noted all of the patients in Group I. conclusion : Ticlopidine is an antiaggregating agent which inhibits primary platelet aggregation induced by ADP, and increases the production of prostaglandin $D_{2}$. Ticlopidine and Aspirin produced a significant inhibition of platelet in the presence of ADP and epinephrine in our study. Acccording to our brief experience, 250 mg of ticlopidine and low dose of Aspirin resulted synergistic superior effect to each drug alone in prevention of thromboembolism after prosthetic cardiac valve replacement.

• 대한원격탐사학회지
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• 제36권6_1호
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• pp.1449-1463
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• 2020

최근 지구온난화에 따른 기후변화 문제의 심각성이 커지면서 국가 온실가스 배출량을 상쇄시킬 수 있는 산림의 탄소흡수에 대한 중요성이 높아지고 있으며, 기후변화협약에 따라 국가의 산림 탄소흡수량을 국지적인 수준에서 과학적이고 정밀하게 산출할 것이 요구되고 있다. 본 연구에서는 위성영상과 일기상 자료를 함께 활용함으로써 산림 광합성의 민감한 일변화를 반영하고, 안정된 산림으로서 대표성을 가지는 광릉숲(Gwangneung Forest) 극상림(climax forest)의 플럭스관측 자료를 참조하여 GPP(gross primary production) 재현 모델을 수립하고, 수종 및 임령에 따른 탄소흡수량 조견표를 적용하여, 우리나라의 국지지역에 최적화된 Tier 2.5 수준의 일일 탄소흡수능 격자자료를 산출하였다. 2013년 1월 1일부터 2015년 12월 31일까지 1,095일간의 실험에서, 일일 기준탄소흡수능(reference amount of CO2 absorption, RACA) 산출 모델은 상관계수 0.948의 높은 정확도를 나타냈으므로, 향후 Tier 3 수준의 일일 실제탄소흡수능(actual amount of CO2 absorption, AACA)을 정확히 산출하기 위해서는 장기간의 상세산림조사 자료와의 결합이 필요할 것이다.