• 대한후두음성언어의학회지
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• 제18권2호
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• pp.108-112
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• 2007

Otolaryngological manifestations of acid reflux include a wide range of pharyngeal and laryngeal symptoms ; and the constellation of symptoms has been called laryngopharyngeal reflux (LPR). In the absence of definite diagnostic criteria, LPR disease remains a subjective entity. A diagnosis of LPR is usually based on response of symptoms to empirical treatment. Investigative modalities such as pH monitoring and, more recently, impedance studies are generally reserved for treatment failures. LPR usually requires more aggressive and prolonged treatment to achieve regression of both symptoms and laryngeal findings. The suppression of gastric acid and secretion with anti-secretary agents has been the mainstay of medical treatment for patients with acid-related disorders. The suppression of gastric acid secretion achieved with Hz-receptor antagonist $(H_2RA)$ has proved suboptimal for relief of reflux symptoms. The rapid development of tolerance and rebound acid hypersecretion after the with-drawal of $H_2RA$ limit their clinical use. Proton pump inhibitors (PPI) have been proved to be very effective for suppressing intragastric acidity, but the optimal dose and duration is unknown. Current evidence indicates that pharmacologic intervention should include, at a minimum, a 3 month trial of twice daily PPI. Symptoms of LPR improve over 2 months of therapy. The physical findings of LPR resolve more slowly than the symptoms and this continues through out at least 6 months of treatment. For most patients with LPR, twice daily dosing with a PPI is usually recommended for an initial treatment for a period of no less than 6 months treatment, and lifetime treatment may be required.

• 한국식생활문화학회지
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• 제35권3호
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• pp.285-293
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• 2020

This study was conducted to monitor the residual pesticides on red pepper powder produced in five regions, which are the major producers of red pepper in Korea, such as Ham-pyeong, An-dong, Yeong-yang, Yeong-gwang, and Cheongyang from 2015 to 2016. Residual pesticides were detected on all samples. Among the 286 pesticides tested, 58 pesticides were detected, with the most frequently detected being chlorfenapyr (93.7%). Twelve types of pesticides (chlorfenapyr, cypermethrin, chlorpyrifos, pyraclostrobin, cyhalothrin, tebuconazole, bifenthrin, deltamethrin, fenvalerate, lufenuron, azoxystrobin, and indoxacarb) were detected in all regions, and 14 types of pesticides were used only in certain regions. An analysis of the residual pesticides showed that none of the pesticides detected exceeded the MRL (Maximum Residue Limits). The Positive List System (PLS) requirements were applied to eight pesticides that had no set MRLs. 0.01 mg/kg (PLS requirements) was exceeded in 12 cases. A comparison of the estimated daily intake (EDI) of pesticides with the acceptable daily intake (ADI) to access their risk revealed %ADI values of 0.001-0.756. Carbofuran showed the highest (0.756%), but most pesticides were below 1%. The results show that residual pesticides in red pepper powder are at safe levels.

• 전기전자학회논문지
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• 제14권1호
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• pp.17-24
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• 2010

본 논문에서는 LBS(Location Based Service) 응용을 위한 독거노인의 일상 활동의 칼로리 소모 예측 모델을 제안한다. 제안한 방식은 PIR (Passive InfraRed) 움직임 센서를 이용하여 독거노인의 활동 패턴을 측정하고, 물리적 활동과 그에 따른 칼로리 소모의 관계를 검토한다. 제안된 움직임 감지 시스템은 개별 노인 주택에 설치되는 센싱 시스템과 중앙 서버 시스템으로 구성된다. 센싱 시스템은 PIR 센서를 장착한 무선 센싱 노드들로 구성된 무선 센서 네트워크 형태로 구현되었고, 각 센서가 감지한 노인들의 움직임은 홈 게이트웨이를 거쳐 중앙 데이터베이스 서버로 저장된다. 서버 시스템은 데이터베이스 서버와 웹 서버로 구성되어 있으며, 웹 기반 모니터링 시스템을 통해 저장된 움직임 데이터를 가공하여 독거노인들의 수발제공자에게 각 노인들의 효율적인 서비스를 제공한다. 실험을 통해 제안한 칼로리 소모 모델의 성능과 적용 가능성을 확인하였다.

• Ocean and Polar Research
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• 제31권1호
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• pp.63-70
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• 2009

Eutrophicated water fed through Mankyeong River and Dongjin River into the new Saemankeum Lakemight seriously affect the water quality and phytoplankton community in the lake. To obtain control reference data for the later studies on environmental changes due to the construction of the Saemankeum Sea Wall, we performed a monthly investigation on the physico-chemical properties of the water and phytoplankton community at 3 stations in the Mankyeong River Estuary over 14 months starting from September 1999. Water temperature ranged from $0.3{\sim}32.9^{\circ}C$ due to the typical seasonal variations in temperate on the coasts and salinity exhibited a wide annual range of $0.2{\sim}33.7$ psu along with regular and huge hourly variations according to tidal cycles. Inorganic nutrients were supplied from rivers to the monitoring station and the whole lake. The average concentration of total-N, $6.99\;mg{\cdot}l^{-1}$, was higher than the water quality for agricultural use with peak values occurring in winter. Species composition showed a seasonal succession pattern, where a high diversity was observedin summer and autumn and vice versa in winter. Hourly variations of water properties in the "Mankyeong bridge" Station were quite regular and well in accordance with the daily tidal cycles. The different degree of sea water intrusion during the flood tide at each of the 3 stations exhibited a different range and variation pattern of water temperature and salinity throughout a day. Hourly changes in species composition were in harmony with the daily tidal cycles, resulting in extremely variable spatio-temporal variation.

• 한국물환경학회지
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• 제25권4호
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• pp.481-493
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• 2009

This study was conducted to performance appraisal of Total Maximum Daily Loads (TMDLs), especially in terms of performance on development & reduction plan and water quality status of unit watershed. Because load allocations for pollution sources were predicted redundantly by uncertainty of prediction, TMDLs master plan has been frequently changed to acquire load allocation for local development. Therefore, It need to be developed more resonable prediction techniques of water pollution sources to preventing the frequent change. It is suggested that the reduction amount have to be distributed properly during the planning period. In other words, it has not to be concentrated on the specific year (especially final year of the planning period). The reason why, if the reduction amount concentrate on the final year of the planning period, allotment loading amount could not be achieved in some cases (e.g., insufficiency of budget, extension of construction duration). If the development plan was developed including uncertain developments, it is necessary to be developed reduction plan considered with them. However, some of the plans in the reduction plan could not be accomplished in some case. Because, it is not considered financial abilities of local governments. Consequently, development plan must be accomplished to avoid uncertain developments, and to consider financial assistance to support the implementation of effective plan. Water quality has been improved in many unit watersheds due to the TMDLs, especially in geum river and yeongsang/seomjin river.

• 대한지역사회영양학회지
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• 제12권5호
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• pp.569-582
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• 2007

This study was carried out to examine information regarding usage of health improving agents and health status of male workers in the Chonnam Yeosu industrial area. We obtained data by means of a questionnaire from 329 men. Of the subjects 44.7% were in their forties, high school education was 43.0%, married was 83.0% and $1,500{\sim}3,000$ thousand won in monthly income was 35.8%. Average height and weight of the subjects was $171.8{\pm}5.4 cm$ and $70.5{\pm}8.1 kg$. Average BMI was $23.8{\pm}2.2$. Drinking rate of respondents was 85.5%, the drinking rate of daily workers was significantly higher than rotation workers (p < 0.05). Rotation workers exercised more regularly than daily workers (p < 0.001). Subjective symptoms of the subjects always had eye problems (11.7%), shoulder aches (5.8%), ache in one's empty stomach (4.7%) in decreasing order. 21.4% of the subjects had a disease, and liver disease was the highest in the subjects; the second was cardio-vascular disease. Interval of health food intake was highly irregular (62.7% of respondents), and keeping healthy was the main motivation fur the usage of health foods. Health improving agents included oriental medicine, animal protein based restorative foods, nutrition supplements, health supplements, and natural foods. 33.3% of the subjects took health supplements, nutrition supplements (29.1%), oriental medicine (20.6%), natural foods (16.7%) and animal protein based restorative foods (3.9%), in respective order. Health improving agents were consumed higher in liver disease than other diseases. This study suggests that nutritional education and monitoring should be implemented for industrial workers to prevent life-habit diseases and to keep proper self-management of health status under special environments.

• 한국대기환경학회지
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• 제16권6호
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• pp.607-623
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• 2000

Major trends of ozone concentration variations in Korea were investigated by using observation data from around 100 stations for the period of 1991∼1997. In addition, important regulating those variations were inferred. Three measures such as the number of days exceeding 80ppb, the 95th percentile of daily maxima, and the annual average concentration were used for the analysis of multi-scale ozone concentration variations. Three areas in the southwest (Sosan, Mokpo, and Cheju) of which monitoring has been operated since 1995 showed the highest annual average concentrations over; this was noted because of the high annual average in the Yosu area in the early 1990s. Large increases in annual average concentrations were observed along the relatively cleaner areas connecting Kangnung and Kwangju(northeast to southwest), in contrast to polluted areas connecting Seoul and Pusan(northeast to southeast). Both the number of exceedance days and the daily maximum concentration were nearly constant in the Greater Seoul Area in spite of interannual flucturations associated with year-to-year changes in air temperature. Within the Greater Seoul Area, all three measures usually showed the same trend; they decreased in the middle and west and increased in the east and northeast. All three measures including the number of exceedance days increased largely at Sillim where the average concentration was high but no exceedance days were recorded in the early 1999s, Nationwide ozone concentration variations appear to be determined by the competitive influence of long-range transport and local urban emissions, Within the city including the Greater Seoul Area, changes in emission which accompany changes in population and in the number if vehicles ( in the process of urban development) were found to be important components of ozone concentration variations.

• Imaging Science in Dentistry
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• 제38권1호
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• pp.29-37
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• 2008

Purpose: The aim of this study was to observe the bony change in the OVX rat longitudinally and to study the alendronate effect. Materials and Methods: Eighteen Sprague-Dewley rats, eight-week old each, were randomly assigned into three groups: one of those sham-operated (N=4), the other two were OVX: saline-treated (N=7) and alendronate-treated group (N=7). The saline-treated group was administered with saline solution (0.1mL/100g) daily, while the alendronate-treated group was given alendronate (1mg/kg, Sigma-Aldrich Corp. Korea) daily. Micro-CT scannings of the lumbar were consecutively done at baseline, at 3-week intervals during 9 weeks. Two and three dimensional bony analysis were done. Bone mineral density (BMD) was measured with Piximus (GE Lunar Co. USA). The average values of these three methods were compared with each group. Results: After 6 weeks the BMD of the OVX group showed lower tendency than that of sham group. After 6 weeks many 3D parameters of micro-CT showed higher values in the OVX-alendronate group compared with the OVXsaline group. Most 2D bony parameters were higher in the OVX-alendronate group compared with the OVX-saline group at 9 weeks. Conclusion: This study showed low BMD of the OVX group after 6 weeks and showed the effect of alendronate on the BMD and bony structures of ovariectomized rats. This study also showed usefulness of in vivo micro-CT in monitoring individual bone changes over time.

• 한국동물위생학회지
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• 제35권3호
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• pp.231-237
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• 2012

In this study, monitoring of food additives as an artificial sweeteners on favorite dairy products of children, which are deal at supermarket, was performed. We analyzed aspartame, acesulfame-K, sodium saccharin, and sucralose from total 206 dairy products which are fermented milk, ice-creams and others. Aspartame was detected from 3 cases of fermented milk. Sucralose was detected from 10 cases of processed milk and 2 cases of fermented milk. The detected concentration was followed [average (minimum~maximum)]: aspartame 34.6 mg/kg (2.9~97.9 mg/kg), sucralose 29.8 mg/kg (5.5~67.7 mg/kg). The level of intakes of detected sweeteners were evaluated by comparisons with the acceptable daily intake (ADI) data established by the joint FAO/WHO expert committee on food additives. The estimated daily intake (EDI) of aspartame and sucralose per day were 0.37 mg/day, 0.20~0.32 mg/day. The intake levels were 0.05~0.8%, which were all within safe levels.

• 한국농공학회논문집
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• 제57권1호
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• pp.69-78
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• 2015

The objective of this study was to investigate characteristics of irrigation return flow from paddy block in a reservoir irrigated district during growing seasons. The irrigation return flow was divided into three parts, quick return flow from irrigation canal (RFI), quick return flow from drainage canal (RFD), and delayed return flow (DRF). The RFI was calculated from water level and stage-discharge relationships at the ends of the irrigation canals. The DRF was estimated using measured infiltration amount from paddy fields of the irrigated district. A combined monitoring and modeling method was used to estimate the RFD by subtracting surface runoff from surface drainage. The paddy block irrigated from the Idong reservoir was selected to study the irrigation return flow components. The results showed that daily agricultural water supply (AWS), the RFI, and the RFD were $27.4mm\;day^{-1}$, $4.9mm\;day^{-1}$, and $19.8mm\;day^{-1}$, respectively in May, which were greater than other months (p<0.05). The return flow ratio of the RFI and the RFD were the greatest in July (34.6%) and May (72.3%), respectively. The daily AWS was closely correlated with the RFD (correlation coefficients of 0.76~0.86) in except for July with, while correlation coefficient with the RFI were 0.56 and 0.42 in June and July, respectively (p<0.01). The total irrigation return flow was 1,965 mm in 2011, and 1,588 mm in 2012, resulting in total return flow ratio of 84.6% and 79.1%, respectively. This results indicate that substantial amounts of agricultural water were returned to streams as irrigation return flow. Thus, irrigation return flow should be fully considered into the agricultural water resources planning in Korea.