• Journal of Electrochemical Science and Technology
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• v.9 no.4
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• pp.276-281
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• 2018

High concentration of copper in mezcal, a representative Mexican spirituous alcoholic beverage, is a serious problem due to the damage that it may cause to human health. A cyclic voltammetry and square wave anodic stripping voltammetry study of copper (II) in three commercial mezcal samples based on glassy carbon electrode response was undertaken. The analysis was developed using a simulated matrix solution ($EtOH/H_2O$ (1:1), 0.1 M $LiClO_4$ and AcOH/AcONa 0.05 M/0.008 M), with Cu (II) concentrations in the range 0 - 1 ppm. Direct electrochemical analysis of mezcal samples was complicated by the presence of different organic compounds in the matrix. The analytical signal of Cu (II) in the spirituous was notably improved and the interferences caused by organic compounds were minimized, by diluting the mezcal samples 10% with $EtOH/H_2O$ (1:1) solution. An efficient quantification of Cu (II) was obtained from the calibration curve by the SWASV and using the internal standard method (Cd (II)) in commercial samples (1.2-6.7 ppm); the results were correlated satisfactorily with the values obtained by AAS.

• ETRI Journal
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• v.43 no.4
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• pp.660-673
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• 2021

To efficiently use frequency resources, the next 6th generation mobile communication technology must solve the problem of out-of-band emission (OoBE) of cyclic prefix (CP) orthogonal frequency division multiplexing (OFDM), which is not solved in 5th generation technology. This study describes a new zero insertion technique to replace an existing filtering scheme to solve this internal problem in OFDM signals. In the development of the proposed scheme, a precoder with a two-dimensional structure is first designed by generating a two-dimensional mapper and using the specialty of each matrix. A spectral shaping technique based on zero insertion instead of a long filter is proposed, so it can be applied not only to long OFDM symbols, but also very short ones. The proposed method shows that the transmitted signal is completely blocked at the bandwidth boundaries of signals according to the current standards, and it is confirmed that the proposed scheme is ideal with respect to bit error rate (BER) performance because its BER is the same as that of CP-OFDM. In addition, the proposed scheme can transformed into a real time structure through vectorizing process with minimal complexity.

• ETRI Journal
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• v.45 no.1
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• pp.45-59
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• 2023

In this paper, to optimize the average delay and power allocation (PA) for system users, we propose a resource scheduling scheme for wireless networks based on Cyclic Prefix Orthogonal Frequency Division Multiplexing (CP-OFDM) according to the first fifth-generation standards. For delay minimization, we solve a throughput maximization problem that considers CPOFDM systems with carrier aggregation (CA). Regarding PA, we consider an approach that involves maximizing goodput using an effective signal-to-noise ratio. An algorithm for jointly solving delay minimization through computation of required user rates and optimizing the power allocated to users is proposed to compose the resource allocation approach. In wireless network simulations, we consider a scenario with the following capabilities: CA, 256-Quadrature Amplitude Modulation, millimeter waves above 6 GHz, and a radio frame structure with 120 KHz spacing between the subcarriers. The performance of the proposed resource allocation algorithm is evaluated and compared with those of other algorithms from the literature using computational simulations in terms of various Quality of Service parameters, such as the throughput, delay, fairness index, and loss rate.

• ETRI Journal
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• v.45 no.2
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• pp.213-225
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• 2023

Physical layer security (PLS) can improve the security of both terrestrial and nonterrestrial wireless communication networks. This study proposes a simplified framework for nonterrestrial cyclic prefixed orthogonal variable spreading factor (OVSF)-encoded multiple-input and multiple-output nonorthogonal multiple access (NOMA) systems to ensure complete network security. Various useful methods are implemented, where both improved sine map and multiple parameter-weighted-type fractional Fourier transform encryption schemes are combined to investigate the effects of hybrid PLS. In addition, OVSF coding with power domain NOMA for multi-user interference reduction and peak-toaverage power ratio (PAPR) reduction is introduced. The performance of $\frac{1}{2}$-rated convolutional, turbo, and repeat and accumulate channel coding with regularized zero-forcing signal detection for forward error correction and improved bit error rate (BER) are also investigated. Simulation results ratify the pertinence of the proposed system in terms of PLS and BER performance improvement with reasonable PAPR.

• ETRI Journal
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• v.46 no.3
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• pp.392-403
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• 2024

Even though generalized frequency division multiplexing is an alternative waveform method expected to replace the orthogonal frequency division multiplexing in the future, its implementation must alleviate channel effects. Least-squares (LS), a low-complexity channel estimation technique, could be improved by using the discrete Fourier transform (DFT) without increasing complexity. Unlike the usage of the LS method, the DFT-based method requires the receiver to know the channel impulse response (CIR) length, which is unknown. This study introduces a simple, yet effective, CIR length estimator by utilizing LS estimation. As the cyclic prefix (CP) length is commonly set to be longer than the CIR length, it is possible to search through the first samples if CP is larger than a threshold set using the remaining samples. An adaptive scale is also designed to lower the error probability of the estimation, and a simple signal-to-interference-noise ratio estimation is also proposed by utilizing a sparse preamble to support the use of the scale. A software simulation is used to show the ability of the proposed system to estimate the CIR length. Due to shorter CIR length of rural area, the performance is slightly poorer compared to urban environment. Nevertheless, satisfactory performance is shown for both environments.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.10C
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• pp.1017-1026
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• 2005

In burst OFDM system, the frame synchronization should be performed first for the acquisition of received frame and the estimation of the correct FFT-window position. The conventional frame synchronization algorithms using design features of the preamble symbol, the repetition pattern of the OFDM symbol by pilot sub-carrier allocation rule and Cyclic Prefix(CP), has difficulty in the detection of precise frame timing because its correlation characteristics would increase and decrease gradually. Also, the algorithm based on the correlation between the reference signal and the received signal has performance degradation due to frequency offset. Therefore, we adopt a differential correlation method that is robust to frequency offset and has the clear peak value at the correct frame timing for frame synchronization. However, performance improvement is essential for differential correlation methods, since it usually shows multiple peak values due to the repetition pattern. In this paper, we propose an enhanced frame synchronization algorithm based on the differential correlation method that shows a clear single peak value by using differential correlation between samples of identical repeating pattern. We also introduce a normalization scheme which normalizes the result of differential correlation with signal power to reduce the frame timing error in the high speed mobile channel environments.

• Development and Reproduction
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• v.22 no.1
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• pp.55-64
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• 2018

Previous studies showed that recombinant equine chorionic gonadotropin ($rec-eCG{\beta}/{\alpha}$) exhibits both follicle-stimulating hormone (FSH) and luteinizing hormone (LH)-like activities in rat LHR- and FSHR-expressing cells. In this study, we analyzed signal transduction by eelFSHR and eelLHR upon stimulation with $rec-eCG{\beta}/{\alpha}$ and native eCG. The cyclic adenosine monophosphate (cAMP) stimulation in CHO-K1 cells expressing eelLHR was determined upon exposure to different doses (0-1,450 ng/mL) of $rec-eCG{\beta}/{\alpha}$ and native eCG. The $EC_{50$ values of $rec-eCG{\beta}/{\alpha}$ and native eCG were 172.4 and 786.6 ng/mL, respectively. The activity of $rec-eCG{\beta}/{\alpha}$ was higher than that of native eCG. However, signal transduction in the CHO PathHunter Parental cells expressing eelFSHR was not enhanced by stimulation with both agonist $rec-eCG{\beta}/{\alpha}$ and native eCG. We concluded that $rec-eCG{\beta}/{\alpha}$ and native eCG were completely active in cells expressing eelLHR, similar to the activity in the mammalian cells expressing LHRs. However, $rec-eCG{\beta}/{\alpha}$ and native eCG did not invoke any signaling response in the cells expressing eelFSHR. These results suggest that eCG has a potent activity in cells expressing eelLHR. Thus, we also suggest that $rec-eCG{\beta}/{\alpha}$ can induce eel maturation by administering gonadotropic reagents (LH), such as salmon pituitary extract.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.46 no.5
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• pp.95-103
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• 2009

An efficient symbol time synchronization scheme for IEEE 802.11n MIMO-OFDM based WLAN systems using cyclic shift diversity (CSD) preamble is proposed. CSD is used to prevent unintentional beamforming when the same preamble signal is transmitted through transmit antennas. However, it is difficult to find a proper starting-point of the OFDM symbol with the conventional algorithms because of time offset by multi-peaks which are result from cross-correlation of received CSD preamble with a known short training symbol. In addition, the performance of symbol time sync. is affected by AGC and packet detection position. In this paper, an optimal symbol time synch. algorithm which is composed of the boundary detection scheme between LTS and OFDM symbols, the verification scheme for enhancement of boundary detection accuracy, and the SNR-varying threshold estimation scheme is proposed. Simulation result show that the proposed algorithm has performance gains of 4.3dB in SNR compared to the conventional algorithms at the rate of 1% sync. failure probability for $2{\times}2$ MIMO-OFDM system and 18dB at 0.1% when maximum frequency offset exists. It also can be applied to $4{\times}4$ MIMO-OFDM system without any modification. Hence, it is very suitable for MIMO-OFDM WLAN systems using CSD preamble.

• The Korean Journal of Physiology and Pharmacology
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• v.4 no.6
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• pp.445-453
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• 2000

The present investigation tested the hypothesis that the activation of protein kinase G (PKG) leads to a phosphorylation of $Ca^{2+}-activated$ potassium channel $(K_{Ca}\;channel)$ and is involved in the activation of $K_{Ca}$ channel activity in cerebral arterial smooth muscle cells of the rabbit. Single-channel currents were recorded in cell-attached and inside-out patch configurations of patch-clamp techniques. Both molsidomine derivative 3-morpholinosydnonimine-N-ethylcarbamide $(SIN-1,\;50\;{\mu}M)$ and 8-(4-Chlorophenylthio)-guanosine-3',5'-cyclic monophosphate $(8-pCPT-cGMP,\;100\;{\mu}M),$ a membrane-permeable analogue of cGMP, increased the $K_{Ca}$ channel activity in the cell-attached patch configuration, and the effect was removed upon washout of the drugs. In inside-out patches, single-channel current amplitude was not changed by SIN-1 and 8-pCPT-cGMP. Application of ATP $(100\;{\mu}M),$ cGMP $(100\;{\mu}M),$ ATP+cGMP $(100\;{\mu}M\;each),$ PKG $(5\;U/{\mu}l),$ ATP $(100\;{\mu}M)+PKG\;(5\;U/{\mu}l),$ or cGMP $(100\;{\mu}M)+PKG\;(5\;U/{\mu}l)$ did not increase the channel activity. ATP $(100\;{\mu}M)+cGMP\;(100\;{\mu}M)+PKG\;(5\;U/{\mu}l)$ added directly to the intracellular phase of inside-out patches increased the channel activity with no changes in the conductance. The heat-inactivated PKG had no effect on the channel activity, and the effect of PKG was inhibited by 8-(4-Chlorophenylthio)-guanosine-3',5'-cyclic monophosphate, Rp-isomer $(Rp-pCPT-cGMP,\;100\;{\mu}M),$ a potent inhibitor of PKG or protein phosphatase 2A (PP2A, 1 U/ml). In the presence of okadaic acid (OA, 5 nM), PP2A had no effect on the channel activity. The $K_{Ca}$ channel activity spontaneously decayed to the control level upon washout of ATP, cGMP and PKG, and this was prevented by OA (5 nM) in the medium. These results suggest that the PKG-mediated phosphorylations of $K_{Ca}$ channels, or some associated proteins in the membrane patch increase the activity of the $K_{Ca}$ channel, and the activation may be associated with the vasodilating action.

• The Korean Journal of Physiology and Pharmacology
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• v.20 no.1
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• pp.9-14
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• 2016

Adenosine 3',5'-cyclic monophosphate (cAMP) participates in the regulation of numerous cellular functions, including the $Na^+-K^+$-ATPase (sodium pump). Ouabain, used in the treatment of several heart diseases, is known to increase cAMP levels but its effects on the atrium are not understood. The aim of the present study was to examine the effect of ouabain on the regulation of atrial cAMP production and its roles in atrial endothelin-1 (ET-1) secretion in isolated perfused beating rabbit atria. Our results showed that ouabain ($3.0{\mu}mol/L$) significantly increased atrial dynamics and cAMP levels during recovery period. The ouabain-increased atrial dynamics was blocked by KB-R7943 ($3.0{\mu}mol/L$), an inhibitor for reverse mode of $Na^+-Ca^{2+}$ exchangers (NCX), but did not by L-type $Ca^{2+}$ channel blocker nifedipine ($1.0{\mu}mol/L$) or protein kinase A (PKA) selective inhibitor H-89 ($3.0{\mu}mol/L$). Ouabain also enhanced atrial intracellular cAMP production in response to forskolin and theophyline ($100.0{\mu}mol/L$), an inhibitor of phosphodiesterase, potentiated the ouabain-induced increase in cAMP. Ouabain and 8-Bromo-cAMP ($0.5{\mu}mol/L$) markedly increased atrial ET-1 secretion, which was blocked by H-89 and by PD98059 ($30{\mu}mol/L$), an inhibitor of extracellular-signal-regulated kinase (ERK) without changing ouabain-induced atrial dynamics. Our results demonstrated that ouabain increases atrial cAMP levels and promotes atrial ET-1 secretion via the mitogen-activated protein kinase (MAPK)/ERK signaling pathway. These findings may explain the development of cardiac hypertrophy in response to digitalis-like compounds.