• 한국농공학회지
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• 제38권5호
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• pp.85-94
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• 1996

For the geotechnical analysis in the construction and Deign of the coastal structures, one of the most important factors is the existence of waves. The dynamic behavior and deformation of the seabed subjected to wave load must be considered. It is expected that the soil behavior in the seabed subjected to cyclic wave load is much different from that on the ground subjected to dynamic forces such as earthquake. The purposes of this study are as follows ; Firstly, to provide a testing method to generate wave loads in the laboratory and measuring oscillatory pore water pressures in the unsaturated marine silty sand specimen, Secondly, to analyze the mechanism of wave induced pore water pressures and liquefaction potentials under the conditions in the testing. It is shown that the test set-up manufactured especially for the test is good to generate oscillatory wave pressures to the specimen with sine wave type. From the results of this study, it is understood that the pore water pressure due to induced waves is not accumulated as the wave number increases but is periodically varied with wave passage on still water surface. The magnitude of pore water pressures measured tends to be diminished radically with a certain time lag under the action of both high and low waves as depth increases.

• 한국자원식물학회지
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• 제1권1호
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• pp.8-22
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• 1988

Vincristine and vinblastine isolated from Vinco spp. , and podophyllotoxine derivatives isolated from Podophyllum spp. are usefulas anticancerous components obtaned from higher plants. More thanten antineoplastic compounds are now following them as anticancerousagents from higher plants. In my laboratory, Sarcoma 180A has beenused as the first screening test. By this method, I have found outsome kinds of antineoplastic constituents from active plants extracts .For instance, bisaborane type compounds were isolated from Curcumaxanthorrhiza, one of Indonesian plants; a morphinane type compoundfromCocculus trilobus; cyclic hexapeptides from Rubia akane and R.cordiorta. Seven components having antineoplastic actirity wereisolated from Rubia spp. except. R. tinctoria. Their structures wereelucidated except RA-Vl by chemical reaction and variovs instrumentalanalysis as shown in Fig. Among of them, RA-Vll showed strong activityagainst P388 Lymphocytic leukemia, L2O, B16 melanoma, Lewis lungcarcinoma, colon 38 and Ehrlich carcinoma. RA-V revealed excellentactivity against MM2 mammary carcinoma. The· value of acute LD5O ofRA-ViI were 10. Omg/kg( iP) and 16.5mg/kg( po ) respectiveIy . Therapruticratio was 400, compared with 10 of mitomycin C. QSAR was also appliedto these compounds by elongation of ether and ester side chains atR'. Mechanism of action of RA-Vll was also investigated and wasassumed to be inhibition of protein biosynthesis .

• Asian-Australasian Journal of Animal Sciences
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• 제13권3호
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• pp.390-400
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• 2000

The corpus luteum (CL) is a temporary endocrine gland whose main function is to secrete progesterone to support pregnancy. On the other hand, the cyclic bovine CL has also been shown to be a site of prostaglandin $F_{2{\alpha}}$ ($PGF_{2{\alpha}}$) production. Although there is general agreement that endometrial $PGF_{2{\alpha}}$ is an essential luteolysin in cattle, luteal $PGF_{2{\alpha}}$ seems to play a luteotropic role as an autocrine and/or paracrine factor, especially for the development and maintenance of the CL. This supposition is based on evidence that some of the prerequisites for autocrine/paracrine mechanisms are present, including local production of $PGF_{2{\alpha}}$ and the existence of specific binding sites within the CL. The purpose of this paper is to review the regulation of luteal $PGF_{2{\alpha}}$ secretion, its action on CL as an autocrine and/or paracrine factor and the receptivity of bovine CL to. $PGF_{2{\alpha}}$.

• Steel and Composite Structures
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• 제23권1호
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• pp.53-66
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• 2017

Structures submitted to Fire-After-Earthquake loading situations, are first experiencing inelastic deformations due to the seismic action and are then submitted to the thermal loading. This means that in the case of steel framed structures, at the starting point of the fire, plastic hinges have already been formed at the ends of the beams. The basic objective of this paper is the evaluation of the rotational capacity of steel I-section beams damaged due to prior earthquake loading, at increased temperatures. The study is conducted numerically and three-dimensional models are used in order to capture accurately the nonlinear behaviour of the steel beams. Different levels of earthquake-induced damage are examined in order to study the effect of the initial state of damage to the temperature-evolution of the rotational capacity. The study starts with the reference case where the beam is undamaged and in the sequel cyclic loading patterns are taken into account, which represent earthquakes loads of increasing magnitude. Additionally, the study extends to the evaluation of the ultimate plastic rotation of the steel beams which corresponds to the point where the rotational capacity of the beam is exhausted. The aforementioned value of rotation can be used as a criterion for the determination of the fire-resistance time of the structure in case of Fire-After-Earthquake situations.

• Structural Engineering and Mechanics
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• 제60권2호
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• pp.251-269
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• 2016

In common structural systems, there are some limitations to provide adequate lateral stiffness, high ductility, and architectural openings simultaneously. Consequently, the concept of T-Resisting Frame (TRF) has been introduced to improve the performance of structures. In this study, Configuration of TRF is a Vertical I-shaped Plate Girder (V.P.G) which is placed in the middle of the span and connected to side columns by two Horizontal Plate Girders (H.P.Gs) at each story level. System performance is improved by utilizing rigid connections in link beams (H.P.Gs). Plastic deformation leads to tension field action in H.P.Gs and causes energy dissipation in TRF; therefore, V.P.G. High plastic deformation in web of TRF's members affects the ductility of system. Moreover, in order to prevent shear buckling in web of TRF's members and improve overall performance of the system, appropriate criteria for placement of web stiffeners are presented in this study. In addition, an experimental study is conducted by applying cyclic loading and using finite element models. As a result, hysteresis curves indicate adequate lateral stiffness, stable hysteretic behavior, and high ductility factor of 6.73.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2018년도 추계학술대회
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• pp.360-363
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• 2018

인간의 활동은 척추 옆굽음증, 골반 뒤틀림과 같은 개개인의 신체적 특징부터 기쁨, 분노, 슬픔 등의 감정들까지 다양한 요인들에 영향을 받는다. 하지만 이러한 동작의 특성은 오랜 시간에 걸쳐서 변화하며, 단기적으로 행동의 특성은 크게 변하지 않는다. 사람의 활동 데이터는 시간 흐름에 따라서 변화하는 시계열 적 특징과 각 행동별로 일정한 규칙성을 갖는다. 본 연구에서는 시계열 적 특징을 다루기 위한 순환신경망의 한 종류인 LSTM을 활동유형을 인식하는 기술에 적용하였으며, 측정시간과 LSTM 모델의 구성요소들에대한 파라미터 최적화로 활동유형의 인식률을 개선하였다.

• Earthquakes and Structures
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• 제13권5호
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• pp.473-484
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• 2017

The objective of this paper is to report on a study of the use of unstiffened thin steel plate shear walls (SPSWs) for the seismic performance improvement of reinforced concrete frames with deficient lateral rigidity. The behaviour of reinforced concrete frames during seismic activities was rehabilitated with an alternative and occupant-friendly retrofitting scheme. The study involved tests of eight 1/3 scale, one bay, two storey test specimens under cyclic quasi-static lateral loadings. The first specimen, tested in previous test program, was a reference specimen, and in seven other specimens, steel infill plates were used to replace the conventional infill brick or the concrete panels. The identification of the load-deformation characteristics, the determination of the level of improvement in the overall strength, and the elastic post-buckling stiffness were the main issues investigated during the quasi-static test program. With the introduction of the SPSWs, it was observed that the strength, stiffness and energy absorption capacities were significantly improved. It was also observed that the experimental hysteresis curves were stable, and the composite systems showed excellent energy dissipation capacities due to the formation of a diagonal tension field action along with a diagonal compression buckling of the infill plates.

• Steel and Composite Structures
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• 제2권1호
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• pp.67-84
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• 2002

Traffic decks of steel or composite motorway bridges sometimes provide the opportunity of using the composite action between an existing steel deck and a reinforced concrete plate (RC plate) in the process of rehabilitation, i.e., to increase the load-carrying capacity of the deck for concentrated traffic loads. The steel decks may be orthotropic decks or also unstiffened steel plates, which during the rehabilitation are connected with the RC plate by shear studs, such developing an improved local load distribution by the joint behaviour of the two plate elements. Investigations carried out, both experimentally and numerically, were performed in order to quantitatively assess the combined static behaviour and to qualitatively verify the usability of the structure for dynamic loading. The paper reports on the testing, the numerical simulation as well as the comparison of the results. Conclusions drawn for practical design indicated that the static behaviour of these structures may be very efficient and can also be analysed numerically. Further, the results gave evidence of a highly robust behaviour under fatigue equivalent cyclic traffic loading.

• Structural Engineering and Mechanics
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• 제19권5호
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• pp.581-602
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• 2005

In this paper the accumulation of local damage during the cyclic loading in reinforced high-strength concrete columns is experimentally investigated. Two identical column specimens with annular cross-section and spiral reinforcement were designed and two tests, up to failure, under the action of a constant vertical concentrated force and a time-dependent concentrated horizontal force, were carried out at the LNEC shaking tables facility. Sine type signals, controlled in amplitude, frequency and time duration were used for these experiments. The concept of local damage based on local stiffness degradation is considered in detail and illustrated by experimental results. The specimens were designed and reinforced in such a way that the accumulation of damage was predicted by dominating deformations (cracking and crushing of the concrete) while the increasing of the loading values was a dominating factor of damage. It was observed that the local damage of HSC columns has exposed their anisotropic local behaviour. The damage accumulation was slightly different from the expected in accordance with the continuum damage concept, and a partial random character was observed.

• Steel and Composite Structures
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• 제33권3호
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• pp.347-356
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• 2019

Most of the recent studies have improved the efficiency of FRP jackets for increasing the compressive strength, shear strength, and ductility of reinforced concrete columns; however, the influence of FRP jackets on the flexural capacity is slight. Although new methods such as NSM (near surface mounted) are utilized to solve this problem, yet practical difficulties, behavior dependency on adhesives, and brittle failure necessitate finding better methods. This paper presents the results of an experimental study on the application of fiber-reinforced polymer fastened mechanically to the concrete columns to improve the flexural capacity of RC columns. For this purpose, mechanical fasteners were used to achieve the composite behavior of FRP and concrete columns. The experimental program included five reinforced concrete columns retrofitted by different methods using FRP subjected to constant axial compression and lateral cyclic loading. The experimental results showed that the use of the new method proposed in this paper increased the flexural strength and lateral load capacity of the columns significantly, and good composite action of FRP and RC column was achieved. Moreover, the experimental results were compared with the results obtained from the analytical study based on strain compatibility, and good proximity was reached.