• 제목/요약/키워드: cut-off diameter

검색결과 64건 처리시간 0.026초

A Logistic Model Including Risk Factors for Lymph Node Metastasis Can Improve the Accuracy of Magnetic Resonance Imaging Diagnosis of Rectal Cancer

  • Ogawa, Shimpei;Itabashi, Michio;Hirosawa, Tomoichiro;Hashimoto, Takuzo;Bamba, Yoshiko;Kameoka, Shingo
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권2호
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    • pp.707-712
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    • 2015
  • Background: To evaluate use of magnetic resonance imaging (MRI) and a logistic model including risk factors for lymph node metastasis for improved diagnosis. Materials and Methods: The subjects were 176 patients with rectal cancer who underwent preoperative MRI. The longest lymph node diameter was measured and a cut-off value for positive lymph node metastasis was established based on a receiver operating characteristic (ROC) curve. A logistic model was constructed based on MRI findings and risk factors for lymph node metastasis extracted from logistic-regression analysis. The diagnostic capabilities of MRI alone and those of the logistic model were compared using the area under the curve (AUC) of the ROC curve. Results: The cut-off value was a diameter of 5.47 mm. Diagnosis using MRI had an accuracy of 65.9%, sensitivity 73.5%, specificity 61.3%, positive predictive value (PPV) 62.9%, and negative predictive value (NPV) 72.2% [AUC: 0.6739 (95%CI: 0.6016-0.7388)]. Age (<59) (p=0.0163), pT (T3+T4) (p=0.0001), and BMI (<23.5) (p=0.0003) were extracted as independent risk factors for lymph node metastasis. Diagnosis using MRI with the logistic model had an accuracy of 75.0%, sensitivity 72.3%, specificity 77.4%, PPV 74.1%, and NPV 75.8% [AUC: 0.7853 (95%CI: 0.7098-0.8454)], showing a significantly improved diagnostic capacity using the logistic model (p=0.0002). Conclusions: A logistic model including risk factors for lymph node metastasis can improve the accuracy of MRI diagnosis of rectal cancer.

고속원심분리 사이클론을 이용한 오일 미스트 제거 성능 연구 (A Study on Performance Evaluation for Oil Mist Removal using a High-speed Centrifugal Cyclone)

  • 김수연;김진선;성진호;한방우;김용진;김학준
    • 한국입자에어로졸학회지
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    • 제15권4호
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    • pp.139-148
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    • 2019
  • This study was performed for the application of a high-speed centrifugal cyclone to shale gas mining process. This device uses the centrifugal force to control particles similar to typical cyclones, and the disk located inside the cyclone is forced to rotate using a motor. The pressure difference occurred during the rotating of disk. Hence, inflow rate was generated without a blower fan. In addition, flow rate increased with elevating rpm of motor. The installing the disk in multiple stages on the inner rotor increased the instantaneous disk outlet flow. Hence, the control efficiency of oil particle increased from 1.05% to 31.2%. By modifying the structure of the disk so that the air flow to the opposite direction of the cyclone, the control efficiency of oil particles increased to 81.5%. By increasing the capacity of the motor and the size of the disk, the flow rate was increased to 2.5 ㎥/min because the rpm of motor and pressure difference increased. As rpm of motor increased, the cut-off diameter (dpc) became smaller. Unlike the Lapple's equation, dpc was inversely proportional to the effective number of rotations (Ne). The control efficiency was maintained even if the concentration of oil particles increased, for this reason, the higher the oil concentration, the more particles were accumulated and controlled.

AWJM을 이용한 Al6061 절단조건 최적화에 관한 연구 (A Study on the Optimization of Machining Process for Al6061 Using the AWJM)

  • 이재광;민병현;예상돈;제원수
    • 한국기계가공학회지
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    • 제5권3호
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    • pp.65-70
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    • 2006
  • The AWJM(Abrasive Water-jet Machining) technology is one of the cutting technologies, which can cut various materials with 2 or 3 times of the speed of sound. In this study, processing conditions such as jet-pressure, cutting speed, orifice diameter and stand-off distance, are used by following the design of experiments with 3 levels. Al6061 material which is normally applied on the field, is applied. Through the S/N ratio analysis with measured values, the optimization value of processing conditions to minimize the surface roughness and taper value is obtained. The order of significance is as follows; jet pressure, cutting speed, abrasive mixing ratio, orifice diameter and stand-off distance. RSM(Response Surface Method) is applied to find the optimal processing conditions to minimize both the surface roughness and the taper value by using jet pressure, cutting speed and abrasive mixing ratio.

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배기용 Fan Scroll에 대한 연구 (A Study on the Fan and Scroll for Ventilation)

  • 송성배;박성일;이준세
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2000년도 춘계학술대회논문집
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    • pp.402-406
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    • 2000
  • In the Over-The-Range, the outlet size is limited by the industrial standards. Therefor to enlarge the volume of cavity, the installation height of ventilation fan is become small, the system resistance is higher than before. For that reason, the important design variables such as the diameter of a fan, the scroll expansion angle, etc. which play the significant role on flow rate and noise, are confined. In this study, we made an experiment of the diameter of fans relation to scroll expansion angle and investigated flow rate of the length of fans in enlarged cavity volume of OTR, and then we designed the new scroll to improve the flow rate and noise level. As a result, flow rate increased to 110% compared to current scroll and the blade passing frequency of a fan is disappeared by inclined cut-off shapes.

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Tumor Diameter for Prediction of Recurrence, Disease Free and Overall Survival in Endometrial Cancer Cases

  • Senol, Taylan;Polat, Mesut;Ozkaya, Enis;Karateke, Ates
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권17호
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    • pp.7463-7466
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    • 2015
  • Aims: To analyse the predictors of recurrence, disease free survival and overall survival in cases with endometrial cancer. Materials and Methods: A total of 152 women diagnosed with endometrial cancer were screened using a prospectively collected database including age, smoking history, menopausal status, body mass index, CA125, systemic disorders, tumor histology, tumor grade, lymphovascular space invasion, tumor diameter, cervical involvement, myometrial invasion, adnexal metastases, positive cytology, serosal involvement, other pelvic metastases, type of surgery, fertility sparing approach to assess their ability to predict recurrence, disease free survival and overall survival. Results: In ROC analyses tumor diameter was a significant predictor of recurrence (AUC:0.771, P<0.001). The optimal cut off value was 3.75 with 82% sensitivity and 63% specificity. In correlation analyses tumor grade (r=0.267, p=0.001), tumor diameter (r=0.297, p<0.001) and the serosal involvement (r=0.464, p<0.001) were found to significantly correlate with the recurrence. In Cox regression analyses when some different combinations of variables included in the model which are found to be significantly associated with the presence of recurrence, tumor diameter was found to be a significant confounder for disease free survival (OR=1.2(95 CI,1.016-1.394, P=0.031). On Cox regression for overall survival only serosal involvement was found to be a significant predictor (OR=20.8 (95 % CI 2.4-179.2, P=0.006). In univariate analysis of tumor diameter > 3.75 cm and the recurrence, there was 14 (21.9 %) cases with recurrence in group with high tumor diameter where as only 3 (3.4 %) cases group with smaller tumor size (Odds ratio:7.9 (95 %CI 2.2-28.9, p<0.001). Conclusions: Although most of the significantly correlated variables are part of the FIGO staging, tumor diameter was also found to be predictor for recurrence with higher values than generally accepted.

단방향 사이클론의 유동 특성에 관한 수치해석적 연구 (Numerical Study on the Flow Characteristics of Uniflow Cyclone)

  • 염정기;짱슈어;신원규
    • 한국가시화정보학회지
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    • 제18권3호
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    • pp.77-83
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    • 2020
  • A uniflow cyclone has simple structure with a single channel in one direction. The one directional particle removal enables the uniflow cyclone to have compact size and low pressure drop. However, it has low collection efficiency compared to conventional cyclones. In this study, the effect of primary geometry on the performance of a uniflow cyclone with swirl vane is numerically investigated for the design of high performance uniflow cyclone. It is found that as the vortex finder diameter is increased, the pressure drop and the collection efficiency are decreased. Also, the same trend is predicted when the vortex finder height is increased. The best collection efficiency is predicted to be obtained when the vortex finder height is equal to the diameter of a cyclone. Reducing the body height by half will increase the pressure drop by 41%. When the body height is decreased, the collection efficiency is first increased and then decreased. The best collection efficiency is obtained when the body height is 4~5 times the cyclone diameter. Overall, the particle collection efficiency is highest when the Dν/D is equal to 0.3. But, the pressure drop is as high as 1592 Pa. Considering both collection efficiency and pressure drop, the best design is when Dν/D, Hν/D, and Hb/D are equal to 0.5, 1, and 5, respectively.

유리판과 단일방향 탄소섬유강화 플라스틱판에서 점원에 의해 발생된 과도적 탄성파의 주파수 해석 (Spectral Analysis of Transient Elastic Waves Generated by Point Source in Glass and Unidirectional CFRP Plates)

  • 이정기;김호철;최명선;김영환
    • 한국음향학회지
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    • 제13권6호
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    • pp.50-59
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    • 1994
  • 유리판과 단일방향(unidirectional) 탄소섬유 강화 복합재료(CFRP)판의 표면에서 연필심을 부러뜨려 발생된 과도적 탄성파를 음원으로부터 멀리 떨어진 서로 다른 위치에 둔 두개의 탐촉자로 검출하였다. 탐촉자에 검출된 과도적 신호의 스펙트럼 분석에 의해 판에서 pulse 형태로 발생된 신호는 Lamb파 분산관계를 따르며 전파하고, 유리판과 단일방향 CFRP판에서의 과도적 신호는 최저 대칭$(S_{0})$, 1차 대칭$(S_{1})$, 1차 비대칭$(A_{l})$ 모드의 최대 군속도 주변의 성분들로 형성되었다. 이러한 최대 군속도 주변 성분은 분산이 비교적 적기 때문에 과도적 신호의 초기부분은 크게 변화되지 않았으며, $A_{1}$ 모드 단절 (cut-off)주파수 이하 영역의 $S_{0}$ 모드가 가장 빠른 군속도로 전파되고 과도적 신호 형성에 크게 기여하는 모드이었다.

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The Level of Squamous Cell Carcinoma Antigen and Lymph Node Metastasis in Locally Advanced Cervical Cancer

  • Lekskul, Navamol;Charakorn, Chuenkamon;Lertkhachonsuk, Arb-Aroon;Rattanasiri, Sasivimol;Ayudhya, Nathpong Israngura Na
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권11호
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    • pp.4719-4722
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    • 2015
  • Background: This study aimed to determine the utility and a cut-off level of serum squamous cell carcinoma antigen (SCC-Ag) to predict lymph node metastasis in locally advanced cervical cancer cases. We also investigated the correlation between SCC-Ag level and lymph node status. Materials and Methods: From June 2009 to June 2014, 232 patients with cervical cancer stage IB2-IVA, who were treated at Ramathibodi Hospital, were recruited. Receiver operating characteristic (ROC) curves were used to identify the best cut-off point of SCC-Ag level to predict lymph node metastasis. Quantile regression was performed to evaluate the correlation between SCC-Ag levels and pelvic lymph node metastasis, paraaortic lymph node metastasis, and parametrial involvement as well as tumor size. Results: Pelvic lymph node metastasis and paraaortic lymph node metastasis were diagnosed in 46.6% and 20.1% of the patients, respectively. The median SCC-Ag level was 6 ng/mL (range, 0.5 to 464.6 ng/mL). The areas under ROC curves between SCC-Ag level and pelvic lymph node metastasis, paraaotic lymph node metastasis, parametrial involvements were low. SCC-Ag level was significantly correlated with paraaortic lymph node status (p=0.045) but not with pelvic lymph node status and parametrial involvement. SCC-Ag level was also related to the tumor diameter (p<0.05). Conclusions: SCC-Ag level is not a good predictor for pelvic and paraaortic lymph node metastasis. However, it is still beneficial to assess the tumor burden of squamous cell carcinoma of the cervix.

주방환기용 그리스 필터의 성능예측 (Performance Prediction of a Grease Filter for Kitchen Ventilation)

  • 김기정;배귀남;김영일;허남건
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2002년도 학술대회지
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    • pp.313-316
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    • 2002
  • A grease filter is used to remove grease generated from a cooking appliance in a kitchen. This numerical study has been conducted to investigate the particle collection characteristics of a grease filter having nominal flowrate of $100m^{3}/h$. The flow field and particle trajectories in the grease filter with a flow chamber were simulated by using the commercial code of STAR-CD. The pressure drop of a grease filter rapidly increases with increasing the air flowrate. The numerical values of the pressure drop are slightly lower than the experimental values when the air flowrates are 50, 75, and $100m^{3}/h$. The particle collection efficiency of a grease filter increases with increasing the particle diameter and the air flowrate, which means that the inertial impaction is a dominant particle removal mechanism in a grease filter The cut-off diameter of the tested grease filter representing $50-{\%}$ collection efficiency is about $11.6{\mu}m$ for water droplets at $100m^{3}/h$.

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주방환기용 그리스 필터의 입자포집 특성에 관한 수치해석 (A Numerical Study on the Particle Collection Characteristics of a Grease Filter for Kitchen Ventilation)

  • 김기정;배귀남;김영일;허남건
    • 설비공학논문집
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    • 제14권10호
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    • pp.792-800
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    • 2002
  • A grease filter is used to remove grease generated from a cooking appliance in a kitchen. This numerical study has been conducted to investigate the particle collection characteristics of a grease filter having nominal flowrate of $100m^3$/h. The flow field and particle trajectories in the grease filter with a flow chamber were simulated by using the commercial code of STAR-CD. The air velocity and pressure distributions were discussed in detail. The pressure drop of a grease filter rapidly increases with increasing the air flowrate. The numerical values of the pressure drop are slightly lower than the experimental values when the air flowrates are 50, 75, and 100㎥/h. The particle collection efficiency of a grease filter increases with increasing the particle diameter, the particle density, and the air flowrate, which means that the inertial impaction is a dominant particle removal mechanism in a grease filter. The cut-off diameter of the tested grease filter representing 50-% collection efficiency is about 11.6$\mu$m for water droplets at $100m^3$/h.