• Title/Summary/Keyword: curcuma

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High Purity Extraction and Simultaneous High-performance Liquid Chromatography Analysis of Curcuminoids in Turmeric (강황에서 curcuminoids의 고순도 추출 및 고성능 액체 크로마토그래피 동시분석)

  • Lee, Kwang-Jin;Ma, Jin-Yeul;Kim, Young-Sik;Kim, Dong-Seon;Jin, Yinzhe
    • Journal of Applied Biological Chemistry
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    • v.55 no.1
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    • pp.61-65
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    • 2012
  • Three major curcuminoids in turmeric (Curcuma longa), curcumin, demethoxycurcumin, and bisdemethoxycurcumin, were efficiently extracted by optimizing extraction condition and simultaneously analyzed and identified using reverse phase high-performance liquid chromatography, thin-layer chromatography, and liquid chromatography-mass spectrometry method. The highest yield of extraction amount 0.279 g, 9.30% was obtained by dipping method with extraction time of 7 h.

Biological screening of 100 plant extracts for cosmetic use (1) Antioxidative activity and free radical scavenging activity

  • Kim, Jeong-Ha;Kim, Beom-Jun;Seok, Chung-Hyun;Won, Il;Kim, Jeong-Haeng;Kim, Hyun-Pyo;Heo, Moon-Young
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.22 no.2
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    • pp.115-123
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    • 1996
  • Methanolic aqueous extracts of 100 plants were screened for antioxidative activity using Fenton's reagen/ethyl linoeate system and free radical scavenging activity using DPPH free radical generating system. The results suggest that at least six plants including Eugenia caryophyllata, Alpinia offiicinarum, Rhus verniciflua, Curcuma longa, Rheum palmatvm and Evodia officinalis may be the potential sources of antioxidant, But only one plant, Cornus officinalis, may be the potential source of free radical scavenger from natural plants.

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Effect of ethanolic extract of some anti-asthmatic herbs on clonidine and haloperidol-induced catalepsy in mice

  • Dhanalakshmi, S.;Khaserao, S.S.;Kasture, S.B.
    • Advances in Traditional Medicine
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    • v.4 no.2
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    • pp.95-99
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    • 2004
  • The ethanolic extract of some medicinal plants having anti-asthmatic activity such as Solanum xanthocarpum, Curcuma longa, Glycyrrhiza glabra, Piper longum, A. vasica, A. lebbeck, and Tinospora cordifolia was evaluated for antihistaminic and anti-cataleptic activity. The aqueous solution of ethanolic extract of S. xanthocarpum and G. glabra potentiated histamine-induced tracheal chain contractions. Whereas, C. longa, P. longum, and T. cordifolia, and A. lebbeck were without any significant effect on histamine. Only A. vasica inhibited histamine-induced tracheal chain contraction. G. glabra per se produced contraction of the tracheal chain, which was blocked by pretreatment with atropine. Single dose of S. xanthocarpum potentiated clonidine-induced catalepsy but on repeated doses (once in a day for 3 days) inhibited catalepsy. Pretreatment with ethanolic extract of C. longa, P. longum, T. cordifolia inhibited catalepsy whereas G. glabra and A. lebbeck significantly potentiated clonidine-induced catalepsy. None of the extracts inhibited haloperidol-induced catalepsy. Thus the extracts having antihistaminic activity or mast cell stabilizing activity inhibited clonidineinduced catalepsy.

The Present Condition and the View of Herb Culture in Japan (일본における약초재배の 현황と 전망)

  • 이치로
    • Korean Journal of Plant Resources
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    • v.5 no.2
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    • pp.105-111
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    • 1992
  • It was explained in detail that the present condition of herb culture in Japanese agriculture and the requirement of crude drugs of good and regulqr very hard hit by the market conditionof crude drugs taking ginseng (Panax ginseng C.A.Meyer) and Coptis Rhizome (Coptis japon-ica Makino) as examples. It is not too mach to say that the market is now under the control ofcrude drugs imported from China. The main current of herb culture in Japan will be the con-tract agriculture that the seedlings of good and regular quality are received and are cultivateduntil the enough time, and the farm products are directly handed to the medicinal company fol-lowing the example of zedoary (Curcuma zedoaria Roscoe) .

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Screening of the Inhibiory Effects of Herbal Medicines on the Platelet Activating Facthr(PAP) Binding : Randomly Selected Herbal Medicines (생약 물 추출물의 혈소판 활성화 인자결합 억제효과 검색 : 무작위로 선정한 국내 유통 생약)

  • 한병훈;양현옥;이승룡;조순현;고현정;한용남
    • YAKHAK HOEJI
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    • v.39 no.1
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    • pp.1-5
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    • 1995
  • As a continuation of the previous study, a second group of sixty two aqueous extracts(freeze dried) from natural products was screened for the inhibitory effect of platelet activating factor(PAF) binding to rabbit platelet using 0.6 nM [$^{3}$H]PAF as a radioligand. The results demonstrated that three medicinal plants inhibited 40~50% of [$^{3}$H]PAF equilibrium binding at the concentration of 200 $\mu\textrm{g}$/ml.

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Mutagenicity of Chinese Herbal Anti-cancer Drugs and Their Antimutagenic Activity to Base-pair Substitution Mutagen (치암중초약의 돌연변이유발 및 돌연변이유발 억제효과)

  • Lee, Hyun-Chul
    • The Journal of the Korean Society for Microbiology
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    • v.22 no.2
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    • pp.185-193
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    • 1987
  • Ten species of herbae, which have been used to treat cancers in Chinese medicine, were tested to investigate their mutagenicity or antimutagenicity in S. typhimurium TA97, TA98, TA100, TA1535, and TA1538. Scolopendra centipede was weakly active in reversion of the frameshift mutation in S. typhimurium TA97 strain and the base-pair substitution in TA100 and TA1535 strains. Other herbae such as Coix lachryma, Dianthus superbus, Tricanthoshse kirilowii, Eupatorium formosanum, Lithospermum erythrorhizon, Ansaema japonicum, Curcuma zedoaria, Helicteres angustifolia, and Euonymus sieboldianus did not show any of the mutagenic potential, regardless of the metabolic activation with rat hepatic microsomal fraction. Dianthus superbus, Eupatorium formosanum, and Euonymus sieboldianus exhibited suppressive activities on microbial mutagenesis of N-methyl-N'-nitrosoguanidine, a base-pair substitution mutagen, in TA1535 and TA100 tester strains. The antimutagenic activities of Dianthus superbus and Euonymus sieboldianus appeared to be dose-dependant.

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Dyeing Properties of Protein and Synthetic Fibers with the Tumeric Extracts (울금 색소 추출물에 의한 단백질계 및 합성섬유의 염색성)

  • 한신영;최석철
    • Textile Coloration and Finishing
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    • v.12 no.6
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    • pp.396-403
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    • 2000
  • The purpose of this study was to investigate the dyeing properties of silk, wool, nylon and poly(ethylene teraphtlate)〔PET〕 fabrics dyed with Tumeric(Curcuma longa) extracts. The dyeing property and color fastness were investigated by using the extracts and the post mordanting with Aluminum, Copper and Iron salts. In the UV-visible spectra, the maximum absorption of wavelength of the extract with methyl alcohol appeared at 420nm, and that of the extract with distilled water was at 415nm. Increasing the dyeing temperature, the K/S values of dyed fabrics were increased. The optimum dyeing condition was 30∼60 minute of dyeing time at pH 5∼5.6. Surface colors of silk and wool became dark by using mordants compared to those of nylon and PET fabrics. The drycleaning fastness of fabrics dyed with the extracts was good. The laundering and light fastness were improved by using mordants.

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Curcumin: a Polyphenol with Molecular Targets for Cancer Control

  • Qadir, Muhammad Imran;Naqvi, Syeda Tahira Qousain;Muhammad, Syed Aun
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.6
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    • pp.2735-2739
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    • 2016
  • Curcumin, is a polyphenol from Curcuma longa (turmeric plant), is a polyphenol that belongs to the ginger family which has long been used in Ayurveda medicines to treat various diseases such as asthma, anorexia, coughing, hepatic diseases, diabetes, heart diseases, wound healing and Alzheimer's. Various studies have shown that curcumin has anti-infectious, anti-inflammatory, anti-oxidant, hepatoprotective, thrombosuppressive, cardio protective, anti-arthritic, chemo preventive and anti-carcinogenic activities. It may suppress both initiation and progression stages of cancer. Anticancer activity of curcumin is due to negative regulation of inflammatory cytokines, transcription factors, protein kinases, reactive oxygen species (ROS) and oncogenes. This review focuses on the different targets of curcumin to treat cancer.

Inhibitory activity of diarylheptanoids on farnesyl protein transferase

  • Kang, Hyun-Mi;Jeon, Sun-Bok;Son, Kwang-Hee;Yang, Deok-Cho;Han, Dong-Cho;Kwon, Byoung-Mog
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.265.2-265.2
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    • 2003
  • Diarylheptanoids [curcumin (1), demethoxycurcumin (2), bisdemethoxycurcumin (3), bisdimethoxymethylcurcumin (4), and 1,2-dihydrobis(de-O-methyl)curcumin (5)] were isolated from the methanolic extract of Curcuma longa L. and A new cyclic diarylheptanoiid (6) and a known compound 7 were isolated from fruits of Alnus japonica S. Diarylheptanoids (1-3) inhibited farnesyl protein transferase (FTPase) with an IC50 of 29-50 $\mu\textrm{m}$. (omitted)

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Structure and Development of Stomata in the Leaves of Some Zingiberaceae

  • Nyawuame, H.G.K.;Gill, L.S.
    • Journal of Plant Biology
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    • v.33 no.3
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    • pp.169-172
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    • 1990
  • The epidermal structure and development of stomata in four taxa of Zingiberaceae viz: Aframomum melegueta K. Schum, Aframomum sceptrum K. Schum, Curcuma longa L. and Zingiber officinale Rosc. have been investigated. Unicellular, eglandular trichomes are observed on the epidermis of A. sceptrum and Z. officienal. Anomocytic stomata with agenous ontogeny, paracitic stomata with eumesogenous ontogeny and tetracytic stomata with mesoperigenous ontogency are recorded in Z. officinale, Aframomum species and C. longa respectively. Stomata of Z. officinale are the smallest in size (20.6$\times$14.3$\times$10.5${\mu}{\textrm}{m}$) while those of C. longa are the largest (42.5$\times$31.5$\times$20.2${\mu}{\textrm}{m}$). These two taxa also recorded the highest (43.7/mm2) and lowest (28.6/mm2) stomatal frequency respectively which suggests a linear regression of frequency on size.

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