• 제목/요약/키워드: crude extracts

검색결과 935건 처리시간 0.029초

Phenolic Compounds from Fruits of Amorpha fruticosa L.

  • Lee, hak-Ju;Lee, Hyun-Jung;Park, Il-Kwon;Shin, Sang-Chul;Lee, Myung-Koo;Paik, Ki-Hyon
    • 대한약학회:학술대회논문집
    • /
    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
    • /
    • pp.190.4-191
    • /
    • 2003
  • This study was carried out to examine the constituents of Amorpha fruticosa (Leguminosae), a shrub originated from North Africa. Dried and ground fruit of A. fruticosa were extracted with methanol and then concentrated to give the crude extracts. The crude extracts was successively fractioned with organic sovents, such as n-hexane, CH$_2$Cl$_2$ and EtOAc. Seven compounds were isolated from the fruits of A. fruticosa. On the basis of spectrosopic data, the structures of these compounds were determined as: kaempferol 7-O-${\alpha}$-L-rhamnopyranoside (I), methyl 3,4,5- trihydroxybenzoate (methyl gallate, II), tephrosin (III), dalbinol (IV), gallic acid (V), 2",4",5",7-tetramethoxyisofavone (Ⅵ) and Dalbinol 2"-O-${\beta}$-D-Glucopyranoside (Ⅶ) respectively. (omitted)

  • PDF

Liposome의 광산화반응에 미치는 인삼추출물의 영향 제1보. Hydroperoxide 생성 억제 효과 (The Effect of Ginseng Extracts on the Photooxidation of Liposome I. The protective effect of the formation of hydroperoxides)

  • 백태홍;김영호;이준홍
    • Journal of Ginseng Research
    • /
    • 제14권3호
    • /
    • pp.379-384
    • /
    • 1990
  • In order to study the lipid peroxidation caused by light and the protective action it in biological memberane, reverse-phase evaporation liposome (REV) was employed as a model memberance and the effect of several antioxidants and ginseng water extracts were tested. In the presence of photosensitizer, liposome was oxidized easily and the oxidation index dut to the peroxidation was increased. The oxidation index of liposome was increased according to the increase in temperature. When dl-${\alpha}$-tocopherol, ${\beta}$-carotene or L-ascorbic acid was added into the reaction mixture, the photooxidation of liposome was inhibited. Ginseng water extract and crude saponin inhibited the rate of oxidation index of liposome in low concentration but increase in high concentration. On the other hand, when lipid hydroperoxide of liposome was tested by ferrothiocyanate method, ginseng water extract and crude saponin acted as antioxidants.

  • PDF

면양태아피부추출액(緬羊胎兒皮膚抽出液)의 세포면역(細胞免疫) 기능저하(機能低下) 효과(效果)에 관(關)한 연구(硏究) (Immunosuppression Associated with Ovine Foetal Skin Extracts)

  • 전무형
    • 농업과학연구
    • /
    • 제11권2호
    • /
    • pp.344-351
    • /
    • 1984
  • 3M KCI로 면양태아피부조직(緬羊胎兒皮膚組織) 추출액(抽出液)을 제조(製造)하여 정상면양(正常緬羊)에 접종(接種)했을 때 접종(接種) 면양(緬羊)의 혈청(血淸)에는 임파구아회식능(淋巴球芽會殖能)(Iymphocyte blastogenicity)을 조지(阻止)시키는 효과(效果)가 있었다. 임파구(淋巴球)에서 보다 면양인상세포암(緬羊鱗狀細胞癌) 조직항원(組織抗原)에 감작(感作)된 임파구(淋巴球)에서 더욱 현저히 나타났다(P<0.001). Crude 3M KCI 추출액(抽出液)을 Sephadex G-150 Column으로 분획(分劃)했을 때 4개의 protein peak 가 나타났으며, 생체내(生體內)에서나 시험관내(試驗管內)에서 세포면역조지효과(細胞免疫阻止效果)를 나타내는 것은 Peak IV였다. 면양태아피부조직(緬羊胎兒皮膚組織) 추출액(抽出液)과 면양린상세포암조직(緬羊鱗狀細胞癌組織) 추출액(抽出液)의 세포면역기능(細胞免疫機能) 저하효과(低下效果)는 동일한 면역저하인자(免疫低下因子)(immunosuppressor)에 의해서 이뤄진다고 고찰(考察)된다.

  • PDF

감마선 조사가 파프리카와 매실 추출물로 제조된 돈육포의 품질특성에 미치는 영향 (Effect of Gamma-irradiation on the Quality Properties of Pork Jerky Prepared with Paprika and Japanese Apricot Extracts)

  • 박경숙
    • 방사선산업학회지
    • /
    • 제5권4호
    • /
    • pp.383-391
    • /
    • 2011
  • This study was conducted to investigate the applicability of gamma irradiation for improving the quality of paprika and Japanese apricot extract-treated nitrite free pork jerky. Pork jerky was gamma-irradiated at 0, 3, 5, 7 and 10 kGy and physiochemical properties such as proximate composition, 2-thiobarbituric acid (TBARS) values, color stability, texture, and sensory property were then evaluated. The results showed that the treatment of paprika and Japanese apricot extract to the pork jerky increased Hunter color value and texture property and at the same time decreased TBARS values. When gamma irradiated, natural pigment extract-treated pork jerky did not produce any change in its proximate composition (moisture, crude protein, crude lipid contents), and TBARS values. However, the redness (a-value) of pork jerky increased as the irradiation dose increased, whereas shear force of pork jerky was decreased. Sensory result showed that gamma irradiation induced to decrease the sensory scores. Therefore, these results suggest that gamma irradiation and the addition of paprika and Japanese apricot extracts could be an effective mean to improve color and texture of restructured pork jerky without use of nitrite.

α-amylase and α-glucosidase inhibition effects of Korean edible brown, green, and red seaweed extracts

  • Ju-Won Ryu;Myeong Seok Lee;Mi-Jin Yim;Jeong Min, Lee;Dae-Sung Lee;Young-Mog Kim;Sung-Hwan Eom
    • Fisheries and Aquatic Sciences
    • /
    • 제26권3호
    • /
    • pp.181-187
    • /
    • 2023
  • The control of intestinal α-amylase and α-glucosidase is an effective therapeutic strategy for prevention of post-prandial hyperglycemia associated with diabetes mellitus. The objective of this study was to evaluate the anti-diabetes activities of Korean edible seaweed against α-amylase and α-glucosidase, two carbolytic enzymes involved in serum glucose regulation. Of the 41 species initially screened, Cladophora wrightiana var. minor, Eisenia bicyclis, Ecklonia cava, Ishige foliacea, and Ishige okamurae exhibited the strongest inhibitory activities from brown seaweeds. Asparagopsis taxiformis showed the strongest inhibitory effects from red seaweeds. The results of this study suggest that the crude brown seaweed extracts (C. wrightiana var. minor, E. bicyclis, E. cava, I. foliacea, and I. okamurae) and crude red seaweed extracts (A. taxiformis) may have beneficial effects suppressing the rise in postprandial hyperglycemia through the inhibition of α-amylase and α-glucosidase.

인삼엑기스 제조에 관한 연구 제1보, 수삼 엑기스 제조 (A Study on the Production of Ginseng Extracts 1. Production of extracts from fresh ginseng)

  • 김해중;임무현;조규성;주현규;이석건
    • Journal of Ginseng Research
    • /
    • 제4권1호
    • /
    • pp.1-7
    • /
    • 1980
  • In order to establish effective extracting method of ginseng extracts from fresh ginseng, the yield, chemical composition, physical properties and organoleptic quality of the extracts, which are extracted with various concentrations of ethanol, were investigated. The results are as follows : 1. The yield of the extracts was increased with decreasing the concentration of ethanol as solvent. As in case of water as a solvents, the highest yield was achieved when 23.64% of water was used. The yield were 12.3% and 9.05%, when 70% and 90% of ethanol were used, respectively lively. 2. Crude protein content is the highest level and nitrogen·free extracts content is the lowest at the concentration of 50% ethanol. Lipid was increased linerly while ash was decreased as increment of ethanol concentration. 3. Viscosity and residue of the extracts also decreased in accordance with the increament of ethanol concentration and the transmittance value and pH of extract solutions were almost similar except transmittance value of the water extracts. 4. The extracts extracted with 70% ethanol gave the best result of sensory test. The total sensory test score of each extracts (70%, 90%, 50%, 0% and 30%) were 70, 65, 50, 46 and 41, respectively.

  • PDF

수종생약의 Brine Shrimp 독성에 관한 연구(I) (Studies on the Brine Shrimp Toxicity of Crude Drugs (I))

  • 김윤철;김정희
    • 생약학회지
    • /
    • 제24권3호
    • /
    • pp.263-265
    • /
    • 1993
  • Brine shrimp toxicity of water extracts of twenty three crude drugs was tested by the brine shrimp bioassay. Eight crude drugs were shown to have 100% mortality in $1000{\;}{\mu}g/ml$. They were fractionated by Amberlite XAD-2 column chromatography and were tested by the brine shrimp bioassay. Methanol fraction of Rhei Rhizoma $(LC_{50}=49.60{\;}{\mu}g/ml)$ and Cantharis $(LC_{50}=54.08{\;}{\mu}g/ml)$ were shown to have potent brine shrimp toxicity in this test.

  • PDF

Regulation of the absorption of dietary sugar by $\alpha$-glucosidase inhibitors from herbal medicines

  • Yun, Yun-Ha;Lee, Shin-Seok;Chung, Nam-Yong;Yim, Dong-Sool;Lee, Sook-Yeon;Ha, Nam-Joo;Kim, Kyung-Jae
    • 대한약학회:학술대회논문집
    • /
    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
    • /
    • pp.391.2-391.2
    • /
    • 2002
  • The inhibitory activity of several crude drugs on $\alpha$-glucosidase, which are the key enzyme for carbohydrate digestion and the prevention of diabetic complications. was investigated. This experiment was designed to examine the hypoglycaemic effect of four water extracts crude drugs. We found two drugs. Mori radicis Cortex and Cudraniae radicis Cortex in several crude drugs remarkably inhibited $\alpha$-glucosidase. Two crude drugs were examined in streptozotocin induced high blood glucose mice. (omitted)

  • PDF

고추 탄저병균에 대한 옻나무 추출물의 항진균 효과 (Antifungal Activity of Crude Extract Compound from Rhus verniciflua Against Anthracnose Fungi (Collectotrichum spp.) of Red-Pepper)

  • 송치현;정종배;정병룡;박세영;이용세
    • 한국환경농학회지
    • /
    • 제31권1호
    • /
    • pp.60-67
    • /
    • 2012
  • 옻나무 주성분인 조추출액의 고추 탄저병균에 대한 항진균활성을 조사한 결과 1.0 mg urushiol/mL PDA 농도에서 18.3-39.5%의 억제효과가 있었으며, 푸른 고추에 병원성이 강한 것으로 조사된 GC계열의 균주보다는 DC계열의 균주에 대한 효과가 높았다. Urushiol의 농도가 1.0 mg/mL 일 경우 약 70% 정도의 포자가 발아한 PDB 용액에서보다 공시 모든 균주의 포자발아는 50% 이상 억제되었다. 동일한 농도에서 균사생장억제 효과 보다는 포자발아에 대한 억제 효과가 다소 높은 경향을 보였다. 푸른 고추와 붉은 고추에 옻 추출액을 처리하고 공시 탄저병균을 접종한 후 병 발생 억제효과를 in vitro에서 검정한 결과 붉은 고추에 DC 균주를 접종하였을 경우 1.0 mg/mL 농도 처리에서는 75.0%, 0.1 mg/mL 농도 처리에서는 58.0% 로 나타났으며, 푸른고추에 병원성이 강한 GC 균주를 접종하였을 경우에는 각각 68.1% 및 28.3% 탄저병 발생이 억제되었다. 비닐하우스에서 관행재배방법에 의해 고추를 재배하면서 고추 탄저병이 자연발생하기 시작한 8월 21부터 옻 추출액을 1주일 간격으로 3회 살포하고 최종 살포일 7일 후에 전체 고추 열매 중 이병 열매를 조사하여 옻 추출액의 병 발생 억제정도를 구한 결과 1차 조사한 9월 11일에는 무처리 대조구에 비해 옻 조 추출액을 1.0 mg/mL 처리한 시험구에서는 85.0% 탄저병 발생 억제효과를 보였으나, 0.01 mg/mL 처리구에서는 9.8%의 낮은 억제효과를 보였다. 9월 11일 조사 후 이병 열매를 모두 제거한 다음 동일한 방법으로 옻 추출액을 계속처리하고 10월 2일에 조사한 결과 1차 조사 시기보다 대조구의 이병과율이 훨씬 낮은 7.0% 였으며, 옻 추출액 처리효과는 공시 처리 농도별로 각각 60.0, 54.3 및 10.0%로 조사되었다.