• 한국전문물리치료학회지
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• 제30권3호
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• pp.169-173
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• 2023

Background: In terms of physical performance, elastic tape (ET) is known to contribute to injury prevention and performance enhancement. Objects: This study aimed to compare and analyze the effect on lower extremity muscle activity of young adult women with and without ET during squats. Methods: In this study, six healthy, young women were recruited as participants in a university laboratory. Participants were allocated to two groups of three after measuring muscle activity in a pre-test, and the experiment was conducted for a total of two weeks (two sessions). First, 10 half squats were taped once in the first week, and 10 half squats were performed without taping in the second week. The other group did this in reverse and measured muscle activity after the squat was over. Results: As a result of this study, there was no significant difference in the quadriceps with or without ET (Z = -0.11, p > 0.05). Similarly, no significant difference was found in hamstring (Z = -0.31, p > 0.05). Conclusion: No beneficial effect was found on changes in muscle activity following ET application during squats. Further studies require randomized controlled trials that increase the number of participants and the intensity of the intervention, and measure pain, function, and performance rather than muscle properties depending on the biomechanical lifting mechanism.

• Asia pacific journal of information systems
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• 제29권3호
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• pp.382-406
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• 2019

We study the antecedents to tie formation on an (Facebook-like) enterprise social media platform implemented to support cross-boundary connections. Research has produced mixed findings regarding the role of social media in cultivating bridging vs. closed networks. We examine the tie formation patterns of 1,386 enterprise social media users over a two-year period. Specifically, we observe who became (or chose not s become) "friends" with whom at the dyadic level and relate the decisions to various mechanisms that affect one's network to expand, constrain, or bridge. Using logistic and OLS regressions, we find that users tend to form ties via reciprocity and transitivity (with friends of friends), both of which help expand one's network. We also find strong networking tendency toward functional and hierarchical homophily (same business unit and same rank, respectively), which is likely to constrain one's network (closed network structure). We find that one's participation in various online interest groups is likely to open one's network (bridging network structure) while no evidence found for preferential attachment. Overall, we find that enterprise social media offers features, some of which are likely to foster bridging while others foster closed networks via different mechanisms.

• Journal of Pharmaceutical Investigation
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• 제33권3호
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• pp.179-185
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• 2003

Melatonin (MT) is an indole amide pineal hormone. It has not only very short half-life but also pH-sensitive property. The sustained release dosage form which delivers MT in a circadian fashion over 8 h is clinical value. The purpose of this study is to prepare sugar beads using multiple coating methods and enteric-coated in a sustained release to evaluate in vitro release characteristics in simulated gastric and intestinal fluids. The $Eudragit^{\circledR}$ as a polymer, sustained release membrane, and triethylcitrate (TEC) as a plasticzer were used. Multi-coated melatonin delivery system was composed of sugar, various excipients, $Eudragit^{\circledR}$ and enteric materials (e.g. hydroxy propyl methyl cellulose phthalate, HPMCP), and prepared by fluid bed coater. The dissolution test was carried out using the basket method at a stirring speed of 100 rpm at $37^{\circ}C$ in simulated gastric (pH 1.2) and intestinal fluid (pH 7.4). The released amount of MT was determined by High performance liquid chromatography method. The morhologies of surface and cross section of multi-coated beads were observed by scanning electron microscope. Size of multi-coated sugar beads was ranged over $1000{\sim}1300\;{\mu}m$. The release rate of MT from coated beads was limited in simulated gastric fluid (pH 1.2), but it was sustained in intestinal fluid (pH 7.4) during $3{\sim}8$ hours. The MT beads may provide small-intestine-targeted device for oral delivery. Studies on animal and relative experiment are in process.

• Journal of Preventive Medicine and Public Health
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• 제29권3호
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• pp.483-494
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• 1996

The objectives of this study are to estimate the prevalence of diabetes mellitus (DM) and to identify risk factors associated with fasting blood sugar in a rural adult population. We carried out a cross - sectional study on the residents over 30-year old. Among the 1077 eligible subjects, 725 persons responded to the study;the study consisted of interview on family and past history of DM, anthropometry, blood pressure, and blood sugar level in each subjects. Only 707 subjects of 725 participants had fasting blood sugar(FBS) examined and the rest, 18 subjects were had casual blood sugar examined due to failure of fasting over 8 - hour. When subjects had $FBS\geq140mg/dl$, 2 hours postprandial blood sugar level was checked after 75g oral glucose loading. The prevalence of DM was 8.9%, and age standarized prevalence rate adjusted to Korean population of 1995 was 5.8%. Mean and SD of fasting blood sugar in men was $99.8{\pm}22.6$, and in women was $111.5{\pm}29.9$. Mean levels of fasting blood sugar were significantly higher in women than in man and as their ages advanced the prevalences increased in both sexes. PP2 blood sugar levels were significantly higher in elder age and in persons with higher FBS levels than others. The risk factors associated with FBS were past history of diabetes, sex, socioeconomic status and waist - to - hip circumference ratio;the risk of diabetes was increased in female, people with past DM history, central obesity and low socioeconomic state. The low socioeconomic status associated with DM in this study, which is different from other study results, should be pursued in further studies.

• 대한치과보철학회지
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• 제38권1호
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• pp.12-25
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• 2000

To demonstrate possible influences of general bone density on the mandible, histomorphometric analysis was carried out in mandibles and iliac bones and the correlation of the two bone densities was tested. Comparison of bony density in women and men over 60 years in the mandible was carried out too. Quantitative computed tomography(QCT) was taken in cross-section of mandibles at the same site where histomorphometric analysis was peformed to evaluate the reliability of QCT. The analysis included 40 cadavers with no known diseases affecting the bones. The subjects consisted of 15 females and 25 males with a mean age of 60.3 years. Spearman correlation analysis and Wilcoxon rank sum test was performed. The results were as follows. 1. There was statistically no correlation between the mandible and iliac bone in the values of corrected cortical width(CCW), cortical porosity(POR) in cortex, and total bone volume(TBV), mean trabecular plate thickness(MTPT), mean trabecular plate density(MTPD), and mean trabecular plate separation(MTPS) in trabecular bone. 2. Comparison of women and men over 60 years, men had statistically higher bone density than women except fir POR of buccal and lingual cortex, and WTPD of alveolar trabeculae in mandible. 3. There was statistically significant correlation between TBV of trabecular bone and CT No., but not between POR and CT No. in mandible. According to the results above, there was no correlation between mandible and iliac bone density and between mandibular bony density and age. Further studies are required to support the results. A more noninvasive method to be able to measure the bone density of mandible should be developed and it is necessary to accumulate data on the normal values of bone density of mandible according to age and sex. Further study should be carried out about QCT to measure mandibular bony density using QCT.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7713-7720
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• 2015

Background: Colorectal cancer (CRC) is one of the most common cancers. This study aimed to compare the uptake of CRC testing in the general public and in ethnic minorities in Hong Kong. Materials and Methods: This cross-sectional survey covered 2,327 South Asian and Chinese adults aged over 50, recruited from two separate studies. A structured questionnaires were administered by research staff over the telephone or in faceto-face interviews. Results: The uptake rate of CRC testing among South Asians was significantly lower than that of the general population in Hong Kong. Factors associated with the uptake rate were health professional's recommendation, perception of regular visits to doctor, use of complementary therapy, ethnicity, perceived susceptibility to cancer, presence of chronic illness, and education level. In addition, a significant interaction (p<0.05) between ethnicity and health professionals' recommendations was found, after adjustment for the main independent factors identified. Conclusions: Older people with lower educational attainment, without chronic illness and those have lower perceived susceptibility to cancer may be targeted for CRC testing promotion in the society. In addition, health professionals can play a highly influential role in promoting such testing, particularly among ethnic minorities.

• Asian Pacific Journal of Cancer Prevention
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• 제16권15호
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• pp.6375-6379
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• 2015

Background: Cervical cancer is the second most common cancer in women worldwide, with about 500,000 new cases and 270,000 deaths each year. Globally, it is estimated that over one million women currently have cervical cancer, most of whom have not been diagnosed, or have no access to treatment that could cure them or prolong their lives. In the United Arab Emirates (UAE) cervical cancer is the third most common cancer in women. Materials and Methods: A population-based cross-sectional retrospective survey of cervical smear abnormalities was conducted in the Emirate of Abu Dhabi, UAE, from January 2013 to December 2013 by collecting consecutive liquid-based cytology samples from the Department of Pathology at the SKMC Hospital in Abu Dhabi city. Results: The total number of women screened for cervical cancer for the year 2013 at SKMC was 4,593, with 225 (4.89%) abnormal smears. The majority of the abnormal smear results were atypical squamous cells of undetermined significance (ASCUS) 114 (2.48%). This study showed 60% increase in the rate of abnormal cervical smears in the UAE over the last 10 years. In this study the highest incidence of high grade abnormalities were seen in women above the age of 61years (1.73%), this might be due to the fact that this group of women missed the chance of screening of cervical cancer earlier in their lives or could be explained by the well-known second peak of HPV infection seen in many prevalence studies. Conclusions: We conclude that the rate of abnormal cervical smear in the screened Abu Dhabi women is not different from the rate in developed countries. A notable increase in both low and high grade abnormalities has occurred within the last decade.

• 동남아시아연구
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• 제20권2호
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• pp.135-178
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• 2010

This study is to seek alternatives for regional governance related to transnational labor migration issues in Southeast Asia. This study examined the present situation and trends of labor migration in the region, reviewed involved transnational issues, and identified the current issues of governance to seek alternatives for regional governance. The increase in cross-border labor migration is no doubt a sign of growth and dynamism of the region and greater integration of their economies. But it also poses complex policy and management issues as well as transnational issues over such as unequal economic profits, illegal migration, human rights, and social security issues. In this reality, regional governance is a very important theme and the efforts to manage their migration inherently involve fundamental conflict and tension between related countries and regions. However, politics and governance of transnational migrant workers in Southeast Asia are still pursued at the national level. To resolve these issues, it is urgently required to secure not only collaboration between the parties concerned but also governance at the regional level. Findings of this study are: First, although labor migration has been a relatively long-time transnational issue, the history of addressing the issue at the regional governance is very short and still inceptive. Second, given its size, labor migration in Southeast Asia requires effective regional governance but no breakthrough was possible due to the conflict of interests between origin and destination countries and the conflict of logic between the labor market and the state. Third, the issue of labor migration is an important element for the formation of economic and socio-cultural communities the ASEAN countries have pursued. Fourth, it is urgently needed to seek alternatives for good and effective regional governance as a key to resolving these issues over migrant workers in Southeast Asia.

• Tuberculosis and Respiratory Diseases
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• 제57권5호
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• pp.405-410
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• 2004

배 경 : 현재 moxifloxacin은 기존의 quinolone 제제들에 비하여 항결핵효과가 크다고 알려지면서 다제내성 결핵에 많이 사용되어 왔지만 moxifloxacin과 기존의 quinolone간의 교차내성에 대한 보고가 없는 상황에서 기존의 quinolone에 내성인 균주에 대한 moxifloxacin의 효과를 예측하기 어려웠다. 이에 본 연구를 통하여 moxifloxacin과 ofloxacin간의 교차내성을 알아봄으로써 ofloxacin 내성 균주에 대한 moxifloxacin의 항 결핵 효과를 알아보고자 하였다. 방 법 : 2003년 3월부터 2004년 3월까지 폐결핵 치료를 위해서 국립마산병원에 방문 또는 입원하였던 환자들의 객담에서 분리된 M. tuberculosis isolate에 대한 약물감수성 검사상 ofloxacin에 대한 본원 임상 검사실의 내성기준 농도인 $2.5{\mu}g/m{\ell}$의 농도에 내성을 보인 균주 37개와 감성을 보인 균주 16개를 대상으로 하여 ofloxacin 및 moxifloxacin 각각에 대한 MIC를 비례법을 이용하여 조사하였다. 결 과 : Ofloxaicn 감성균주들에 대한 $MIC_{50}$과 $MIC_{90}$은 ofloxacin에서 모두 $1.25{\mu}g/m{\ell}$, moxifloxacin에서는 각각 $0.31{\mu}g/m{\ell}$과 $0.63{\mu}g/m{\ell}$였다. ofloxacin 내성균주들에 대한 $MIC_{50}$은 ofloxacin에서 $10{\mu}g/m{\ell}$ 이상, moxifloxacin에서 $5{\mu}g/m{\ell}$였으며 $MIC_{90}$은 ofloxacin과 moxifloxacin 모두에서 $10{\mu}g/m{\ell}$이상의 값을 보였다. 약물 농도 $2.5{\mu}g/m{\ell}$을 기준으로 한 moxifloxacin의 ofloxacin에 대한 교차 내성률은 67.6%로 나타났다. 결 론 : moxifloxacin은 $10{\mu}g/m{\ell}$의 농도에서 ofloxacin 내성균주의 82.4%(28/34)에서 항결핵 효과가 있었으나 ofloxacin 내성을 포함하는 다제내성 결핵환자에게 사용하기 위해서 좀 더 많은 연구가 필요할 것으로 사료된다.

• Nutritional Sciences
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• 제9권2호
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• pp.92-96
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• 2006

Studies were carried out to determine the effect of feeding diet containing 5% canola oil on growth, feed efficiency, and fatty acid profile of bacon in finishing pigs and of longissimus muscle in horses fattening for meat production. In experiment 1, twenty cross-bred barrows and twenty cross-bred gilts (average weight, 80 kg) were blocked by sex and weight, and five barrows or five gilts were allotted to one of eight pens $(6.25m^2/pen)$, respectively. Four pens (two with barrows and two with gilts) randomly selected were assigned to a control diet containing 5% tallow and the remaining four pens to a diet containing 5% canola oil. The average daily weight gain, daily feed intake and feed efficiency over a 6-wk feeding period were not different (p>0.05) between the two diets, nor was backfat thickness. Fatty acid profile in bacon fat showed that the 0-3 fatty acid ($\alpha-linolenic$ acid) content in pigs fed diet containing 5% canola oil was approximately three times (P<0.01) as much as in pigs fed tallow. In experiment 2, thirty-two Jeju horses (average $weight{\pm}SE,\;244{\pm}5kg$) were blocked by sex and weight, and two horses of the same sex and similar body weight were allotted to one $(15m^2/pen)$ of eight pens. Eight pens (four with males and four with females) selected randomly were assigned to a control diet containing 5% tallow and the remaining eight pens to a diet containing 5% canola oil. The average daily weight gain, daily feed intake and feed efficiency for concentrates without roughages over a 5-month feeding period were not different (P>0.05) between the two diet groups. Fatty acid profile in the muscle fat showed that the 0-3 fatty acid (a-linolenic acid) content in horses fed diet containing 5% canola oil was approximately two times (P<0.01) that in horses fed tallow. The increased (P<0.01) 0-3 fatty acid content in pigs and horses fed canola oil decreased the ratio of n-6 to n-3 fatty acids compared to the control, indicating a significant improvement in pork and horsemeat fatty acid profile for health benefit. Our study demonstrated that feeding diet containing 5% canola oil may help produce pork and horsemeat with more health benefit, increasing their $\alpha-linolenic$ acid content without deleterious effects on growth of pigs and horses.