• Title/Summary/Keyword: cross-over studies

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Studies on the Physical Growth and Development, Standard Body Weight and Normal Adapted Body Weight in Korea (한국인의 표준체중치와 정상적응체중치에 관한 연구)

  • 김대봉;윤태영;최중명;박순영
    • Korean Journal of Health Education and Promotion
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    • v.13 no.1
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    • pp.128-162
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    • 1996
  • Using Random Sampling, the authors measured the body heights and weights of 31,151 persons - 17,102 in males and 14,049 in females from metropolitan, urban and rural areas between 6 to over 80 year old - for the purpose of investigating the type and the actual condition of the Korean's growth and development. At first, on the basis of the results, the authors measured the growth and development, various kinds of physiques, nutritional index of the 6 to 20s age group. Second, the authors presented the standard body weight of males and females by their body height, who were in the end of their growth (20-29 age group). Third, the authors calculated and presented the normal adapted body weight of the age group who were over 30 age after the growth had been completed. Forth, the author presented the obesity rate of the adults over 20 years old by body mass index. Finally, the authors compared chronological change of the Koreans' body heights and body weights with the results of other researchers. 1. Body Measurement Rapid growth, in terms of body height, which is described by a straight line on a growth curve has been observed among males in the ages 6-13 and among females 6-14. That growth curve turned out to be slower among the people of higher ages by both sexes. The cross-over occurred in both sexes at 11-14. The highest growth rate for a year is at 13-16 for males and 11-13 for females. This indicates that females enter a rapidly growing stage 2 years earlier than males. 2. Various Physiques and Nutritional Index Rapid growth, in terms of Relative Body Weight Index, which is described by a straight line, has been observed among males in the ages 6-16 and females in the ages 6-14. The cross-over occurred in both sexes 12.5-14.5 age in the adolescencent period. Whereupon females outgrow males. The Roher Index displayed more good value in case of females than male and in the adolescent period, the level of fullness is lower than after the completion of development. The Kaup Indices of both sexes increase with age. The index is less than 2.0 for males in 6-14 age group and for females in 6-13 age group and with this, it appeared that development of horizontal axis to long axis is poor. The index is more than 2.0 after 15 age group in males and 14 age group in females and developmental state4 age group and for females in 6-13 age group and with this, it appeared that development of horizontal axis to long axis is poor. The index is more than 2.0 after 15 age group in males and 14 age group in females and developmental state Body Mass Index is less than 20 for males 6-14 age group and for females in 6-13 age group. In the case of the higher age group, that index maintains a normal state.

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Comparative Studies on Serological Tests for Actinobacillus pleuropneumoniae Infection in Swine (돼지에서 Actinobacillus pleuropneumoniae의 혈청학적 진단법에 대한 비교연구)

  • 심항섭;우종태;조중현;전무형
    • Korean Journal of Veterinary Service
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    • v.17 no.2
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    • pp.95-113
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    • 1994
  • To establish an effective diagnostic measure for detection of the antibodies against Actinobacillus pleuropneumoniae, the methods for tube agglutination test (TAT), plate agglutination test (PAT), micro-agglutination test(MAT) and agar-gel immunodiffusion test(ID) were improved and standarized, and the comparative studies were carried out. The results obtained through the experiments were summarized as follows. 1. The rabbit hyperimmune sera to reference serotypes 1 to 6 were cross-tested with TAT, PAT, MAT and ID. In the homologous systems, the range of antibody titers in TAT was 80 to 640, showing the cross-reaction in serotypes 3, 4, 5 and 6. The range of antibody titers in PAT was 4 to 64, showing the cross-reaction in serotypes 3, 4, 5 and 6. In ID, the range of antigen titers was 8 to 32, and cross-reaction was observed in serotype 5. 2. The optimal concentration of antigen in PAT and MAT were 100mg /ml and 1.25mg /ml respectively. The most sensitive reaction in MAT was observed in 52$^{\circ}C$ for 18hrs. 3. In ID, the most promising antigen and the buffer for agar-gel were EDTA-treated antigen and 0.05M tris buffer (pH 7.2), respectively. 4. By the tests for 200 swine sera, it was found that the frequency of positive reaction were 203 in TAT, 240 in PAT and 163 in ID. 5. When compared the titers of TAT with those of MAT for 200 swine sera, MAT showed the higher titer than TAT being increased by relative correlation. Int was found that the titer for positive readings were 20 in TAT and 40 in MAT. 6. when compared the results of ID with those of TAT for 200 swine sera, all sera with TAT titer under 10 were negative in ID. Of the sera with TAT titer 20 and 40, 55.1% nd 91.8% were positive in ID, respectively. All sera with TAT titer above 80 were positive in ID. In comparison of ID and MAT, all sera with MAT titer under 20 were negative in ID. Of the sera with MAT titer 40 and 80, 24.7% and 93.9% were positive in ID, respectively. All sera with MAT titer over 160 showed positive in ID. 7. In conclusion, the established MAT showed high sensitivity but low specificity, wherease ID revealed low sensitivity but high specificity.

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Comparison of MCC and SSC Models Based on Numerical Analysis of Consolidation Test (압밀시험의 수치해석에 의한 MCC 모델과 SSC 모델 비교)

  • Kwon, Byenghae;Eam, Sunghoon
    • Journal of The Korean Society of Agricultural Engineers
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    • v.66 no.2
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    • pp.1-12
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    • 2024
  • In order to integrate two consolidation theories of Terzaghi's consolidation theory and Mesri's secondary compression theory and to identify a model suitable for analyzing stress-strain behavior over time, numerical analysis on consolidation tests were conducted using a modified cam-clay model and a soft soil creep model and the following conclusions were obtained. The results of numerical analysis applying the theory that a linear proportional relationship is established between the void ratio at logarithmic scale and the permeability coefficient at logarithmic scale is better agreement with the result of oedometer test than the results of applying constant hydraulic conductivity. The modified cam-clay model is a model that does not include secondary compression, but the slope of the normal consolidation line corresponding to the compression index of the standard consolidation test includes secondary compression, so the actual settlement curve over time is lower than the predicted value through numerical analysis. It always gets smaller. Other previous studies that applied Terzaghi's consolidation theory to consolidation test analysis showed the same results and were cross-confirmed. The soft soil creep model, which includes secondary compression in the theory, showed good agreement in all sections including secondary compression in the consolidation test results. It was judged appropriate to use a soft soil creep model when performing numerical analysis of soft clay ground.

Community Based Cross-sectional Study on the Risk Factors of Dementia among the Elderly in a City (도시지역 노인의 치매 위험요인에 관한 단면연구)

  • Kim, Jung-Soon;Chun, Byung-Chul;Cho, Eu-Soo;Jeong, Ihn-Sook
    • Journal of Preventive Medicine and Public Health
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    • v.35 no.4
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    • pp.313-321
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    • 2002
  • Objectives : To identify the risk factors of dementia among the elderly in a large city. Methods : A cross-sectional study was conducted in July 2001, with potential participants selected by stratified two stage cluster sampling of the elderly population of Keumgog dong, Busan. A total of 452 elderly people aged 65 years and over, underwent a two phase diagnostic procedure. Mini-mental State Examination-Korean (MMSE-K) and Samsung Dementia Questionnaire were used for the 1st stage, and the Clinical Dementia Rating Scale (CDR), the Bartel ADL, and IADL Index, the Korean Geriatric Depression Scale (KGDS), the Modified Hatchinski Ischemic Scale (MHIS), and other laboratory tests were used for the 2nd stage. Results : Of the 446 participants finally chosen, 45 were confirmed with dementia, and 363 as normal, with the rests not confirmed with dementia or as normal, were excluded from the analysis. According to the logistic regression analysis, the risk of dementia was significantly higher In: people aged 80 and above (OR=4.36, 95% CI=1.97-9.62), illiterate (OR=3.58, 95% CI=1.71-7.46), who had a history of strokes (OR=6.35, 95% CI=2.71-14.87), or who had 3 history of hyperlipidemia (OR=4.74, 95% CI=1.65-13.61), compared to their counterparts. Conclusions : These results suggest that efforts to prevent strokes and hyperlipidemia can significantly decrease the risk of dementia.

The cross-lagged effects of unmarried fathers' involvement on children's behavior problems (교차지연 모형을 통한 비혼 아버지의 양육참여와 아동의 문제행동간의 인과관계 검증)

  • Choi, Jeong-Kyun
    • Journal of the Korean Society of Child Welfare
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    • no.59
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    • pp.1-23
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    • 2017
  • Using a subsample of 3,409 unmarried smothers and their children from the Fragile Families and Child Wellbeing study, the present study examined the cross-lagged effects of unmarried fathers' involvement on their children's behavior problems. Father involvement was used as a latent variable to measure the frequency of fathers' visits to the child, fathers' instrumental support, and their supportive parenting. Both variables of father involvement and child behavior problems were repeatedly measured at child ages 3, 5, and 9 to estimate their trends over time. The results indicated that fathers' more active engagement in parenting at child ages 3 to 5 reduced behavior problems in children at ages 5 to 9. Further discussions include programs and services to support unmarried fathers through education and training opportunities for effective parenting, relationship skills, and conflict resolutions as well as policy strategies to encourage their continuous involvement in the lives of their children.

Relative Bioavailability Studies on Two Tablet Preparations of Ofloxacin

  • Shakya, Ashok-K.;Talwar, Naresh;Karajgi, Jayant;Singhai, Akhlesh
    • Archives of Pharmacal Research
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    • v.15 no.3
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    • pp.208-210
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    • 1992
  • Comparative bioavailability of two tablet dosage forms of ofloxacin (either as Hoechst (India) or Ranbaxy preparation ) was investigated. In a randomized cross-over study, eitht healthy human volunteers received single 200 mg dose of film coated ofloxacin in fasting state. The concentration of ofloxacin in the collected saliva and serum samples were measured by high performance liquid chromatography. No significant difference in bioavailability of both preparations was judged from various serum and seliva pharmacokinetic parameters such as peak concentration, time to peak concentration and are under the curves. Intersubject variation was also found to be insignificant.

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Plasma Chemistry Data Research for Plasma Applications

  • Yoon, Jung-Sik
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.08a
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    • pp.77-77
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    • 2012
  • As interest has increased in the interaction between low-temperature plasmas and materials, the role of modeling and simulation of processing in plasma has become important in understanding the effects of charged particles and radicals in plasma applications. Thus in this presentation, we present the theoretical and experimental studies of electron impact cross section for plasma processing gas, such as plasma etching and deposition processes. Also, here the work conducted at the Data Center for Plasma Properties (DCPP) over last 7 years on the systematic synthesis and assessment of fundamental knowledge on low-energy electron interactions with plasma processing gases is briefly summarized and discussed.

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Health Status among Community Elderly in Korea (일 도시지역 노인의 건강상태에 관한 연구)

  • 김혜령
    • Journal of Korean Academy of Nursing
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    • v.33 no.5
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    • pp.544-552
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    • 2003
  • Purpose: This study examined the health status among elderly in community. Method: This is a survey using cross-sectional design. The subjects were 531 elders who were 65 and over in Pusan, Korea. Data were collected by 17 trained interviewers from April 10 to August 26, 2000. Functional status for physical health status, depression, loneliness, self-esteem for psychological health status, and social support for social health status were measured. Result: About forty three percent of the subjects were found as the elderly who need support in physical status. About fifty six percent of the subjects were depressed. The mean score on the Loneliness scale was 40.4, which means relatively higher. For self-esteem, its score was lower than that of elderly who were examined in other studies. The subjects were living in the state of lower social support. The risk factors for vulnerable health status were being female, becoming older, lower income and education, and living alone. Conclusion: This finding indicates that the elderly subjects in Korean community were in poor health status in physical, psychological and social aspects.

Bending and Torsional Behaviors of Thick Composite Channel Beam (두꺼운 복합재료 채널빔의 굽힘 및 비틀림 거동)

  • Park, Mi-Jung;Choi, Yong-Jin;Chun, Heung-Jae;Byun, Joon-Hyung
    • Proceedings of the KSME Conference
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    • 2004.11a
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    • pp.480-485
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    • 2004
  • The applications of composite materials have increased over the past few decades in a variety of structures that require high ratio of stiffness and strength to weight ratios. Recently the thick open section composite beams are used extensively as load carrying members and stiffeners of structural elements. However, most of studies on thick composite beams are limited only to closed section beams. In this study, an open cross-section thick-walled composite beam model which includes coupled stiffness, transverse shear, and warping effects is suggested and the deflections associated with the thick-walled composite beams and thin-walled composite beams are obtained and compared with the finite element analysis results.

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Thirteen-week Repeated-dose Toxicity Studies of STB-HO-BM in Rats (랫드에서 STB-HO-BM에 대한 13주 반복투여 독성연구)

  • Song Si-Whan;Jung Winston;Hong Dong-Ho
    • Toxicological Research
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    • v.22 no.2
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    • pp.135-144
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    • 2006
  • This study was performed to evaluate repeated-dose toxicities of STB-HO-BM in Sprague-Dawley rats. STB-HO-BM was administered orally to rats at dose levels of 0, 100, 300 and 1,000 mg/kg/day for 13 weeks. In recent study, there were no dose related changes in mortality, clinical signs, body weight changes, food and water consumption, opthalmoscopy, organ weights, urine analysis, hematological findings, and biochemical examination of all animals treated with STB-HO-BM. Gross and histopathological findings revealed no evidence of specific toxicity related to STB-HO-BM. These results suggest that the oral no observed adverse effect level (NOAEL) of STB-HO-BM may be over 1,000 mg/kg in rats.