• Journal of Pharmaceutical Investigation
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• v.34 no.4
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• pp.275-281
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• 2004

We have studied the effect of polarity, current density, current duration, crosslinking density, swelling ratio, and permeation enhancers on the transdermal flux of ketoprofen from acrylamide hydrogel. Hydrogel was prepared by free radical crosslinking polymerization of acrylamide. Drug loading was made just before transport experiment by soaking the hydrogel in solution containing drug. In vitro flux study using hairless mouse skin was performed at $36.5^{\circ}C$ using side-by-side diffusion cell, and the drug was analysed using HPLC/UV system. The result showed that, compared to passive flux, the total amount of drug transported increased about 18 folds by the application of $0.4\;mA/cm^2$ cathodal current. Anodal delivery with same current density also increased the total amount of drug transported about 13 folds. It seemed that the increase in flux was due to the electrorepulsion and the increase in passive permeability of the skin by the current application. Flux increased as current density, the duration of current application and loading amount (swelling duration) increased. As the cross linking density of the hydrogel increased, flux clearly decreased. The effect of hydrophilic enhancers (urea, N-methyl pyrrolidone, Tween 20) and some hydrophobic enhancers (propylene glycol monolaurate and isopropyl myristate) was minimal. However, about 3 folds increase in flux was observed when 5% oleic acid was used. Overall, these results provide some useful information on the design of an optimized iontophoretic delivery system of ketoprofen.

• Convergence Security Journal
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• v.12 no.3
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• pp.99-106
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• 2012

Today, the typical web hacking attacks are cross-site scripting(XSS) attacks, injection vulnerabilities, malicious file execution and insecure direct object reference included. Web hacking security systems, access control solutions, access only to the web service and flow inside but do not control the packet. So you have been illegally modified to pass the packet even if the packet is considered as a unnormal packet. The defense system is to fail to appropriate controls. Therefore, in order to ensure a successful web services diagnostic system development is necessary. Web application diagnostic system is real and urgent need and alternative. The diagnostic system development process mu st be carried out step of established diagnostic systems, diagnostic scoping web system vulnerabilities, web application, analysis, security vulnerability assessment and selecting items. And diagnostic system as required by the web system environment using tools, programming languages, interfaces, parameters must be set.

• Proceedings of the KSME Conference
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• 2003.11a
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• pp.658-663
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• 2003

A process of 3-D stereo particle image velocimetry(PIV)was developed for the measurement of an illuminated sliced section field of 3-D complex flows. The present method includes modeling of camera by a calibrator based on the homogeneous coordinate system, transformation of the oblique-angled image to the right-angled image, identification of 2-D velocity vectors by 2-D cross-correlation equation, stereo matching of 2-D velocity vectors of two cameras, accurate calculation of 3-D velocity vectors by homogeneous coordinate system, removal of error vectors by a statistical method followed by a continuity equation criteria, and finally 3-D display as the post processing. An experimental system was also used for the application of the proposed method. Two high speed digital CCD cameras and an Argon-Ion Laser for the illumination were adopted to clarify the time-dependent characteristics of the leading edge extension(LEX) in a highly swept shape applied to a delta wing found in modern air-fighters.

• Proceedings of the KSME Conference
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• 2007.05b
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• pp.3050-3055
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• 2007

A wind turbine is one of the most popular energy conversion systems to generate electricity from the natural renewable energy source and an axial-flow type wind turbine is the most popular system for the electricity generation in the wind farm nowadays. In this study, a cross-flow type turbine has been studied for the application of wind turbine for electricity generation. The target capacity of electric power generation of the model wind turbine developing on the project is 12 volts, 130A/H (about 1.56kW). The important design parameters of the model turbine impeller are the inlet and exit angle of the turbine blade, number of blade, hub/tip ratio and the exit flow angle of the casing. In this study, the radial equilibrium theorem was used to decide the inlet and exit angle of the impller blade and CFD technique was used to have the performance analysis of the designed model power turbine to find out the optimum geometry of the CPT impeller and casing. The designed CPT with 24 impeller blades at ${\alpha}=82^{\circ}$, ${\beta}=40^{\circ}$ of turbine blade angle was estimated to generate 284.6 N.m of indicated torque and 2.14kW of indicated power.

• Corrosion Science and Technology
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• v.13 no.2
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• pp.62-69
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• 2014

A huge number of carbon steel piping components installed in the secondary system of nuclear power plants are exposed to aging mechanisms such as FAC (Flow-Accelerated Corrosion), Cavitation, Flashing, and LDIE (Liquid Droplet Impingement Erosion). Those aging mechanisms can lead to thinning of the piping components. To manage the wall thinning degradation, most of utilities in the world predict the wall thinning rate based on the computational program such as CHECWORKS, COMSY, and BRT-CICERO, evaluate the UT (Ultrasonic Test) data, and determine next inspection timing, repair or replacement, if needed. There are several evaluation methods, such as band, blanket, and strip methods, commonly used for determining the wear of piping components from single UT inspection data. It has been identified that those single UT evaluation methods not only do not consider the manufacturing features of pipes, but also may exclude the data of the most thinned point when determining the representative wear rate of piping components. This paper describes a newly developed single UT evaluation method, E-Cross method, for solving above problems and introduces application examples for several pipes and elbows. It was identified that the E-Cross method using the length and width of UT data excluded the most thinned points appropriate as the single UT evaluation method for thinned piping components.

• Proceedings of the KSRS Conference
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• 2004.10a
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• pp.302-305
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• 2004

The aim of this study is to apply and crossvalidate a spatial logistic multiple-regression model at Boun, Korea, using a Geographic Information System (GIS). Landslide locations in the Boun area were identified by interpretation of aerial photographs and field surveys. Maps of the topography, soil type, forest cover, geology, and land-use were constructed from a spatial database. The factors that influence landslide occurrence, such as slope, aspect, and curvature of topography, were calculated from the topographic database. Texture, material, drainage, and effective soil thickness were extracted from the soil database, and type, diameter, and density of forest were extracted from the forest database. Lithology was extracted from the geological database and land-use was classified from the Landsat TM image satellite image. Landslide susceptibility was analyzed using landslide-occurrence factors by logistic multiple-regression methods. For validation and cross-validation, the result of the analysis was applied both to the study area, Boun, and another area, Youngin, Korea. The validation and cross-validation results showed satisfactory agreement between the susceptibility map and the existing data with respect to landslide locations. The GIS was used to analyze the vast amount of data efficiently, and statistical programs were used to maintain specificity and accuracy.

• Journal of Industrial Technology
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• v.29 no.B
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• pp.17-23
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• 2009

In many cases, clustering algorithms have been used for extracting and discovering useful information from non-linear data. They have made a great effect on performances of the systems dealing with non-linear data. Thus, this paper presents a new approach called hierarchically structured clustering algorithm, and it is applied to the prediction system for non-linear time series data. The proposed hierarchically structured clustering algorithm (called HCKA: Hierarchical Cross-correlation and K-means clustering Algorithms) in which the cross-correlation and k-means clustering algorithm are combined can accept the correlationship of non-linear time series as well as statistical characteristics. First, the optimal differences of data are generated, which can suitably reveal the characteristics of non-linear time series. Second, the generated differences are classified into the upper clusters for their predictors by the cross-correlation clustering algorithm, and then each classified differences are classified again into the lower fuzzy sets by the k-means clustering algorithm. As a result, the proposed method can give an efficient classification and improve the performance. Finally, we demonstrates the effectiveness of the proposed HCKA via typical time series examples.

• Proceedings of the KSRS Conference
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• 2008.03a
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• pp.158-163
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• 2008

In inverse synthetic aperture radar (ISAR) imaging, An ISAR autofocusing algorithm is essential to obtain well-focused ISAR images. Traditional methods have relied on the approximation that the phase error due to target motion is a function of the cross-range dimension only. However, in the stepped-frequency radar system, it tends to become a two-dimensional function of both down-range and cross-range, especially when target's movement is very fast and the pulse repetition frequency (PRF) is low. In order to remove the phase error along down-range, this paper proposes a method called SAEM (subarray averaging and entropy minimization) [1] that uses a subarray averaging concept in conjunction with the entropy cost function in order to find target motion parameters, and a novel 2-D optimization technique with the inherent properties of the proposed entropy-based cost function. A well-focused ISAR image can be obtained from the combination of the proposed method and a traditional autofocus algorithm that removes the phase error along the cross-range dimension. The effectiveness of this method is illustrated and analyzed with simulated targets comprised of point scatters.

• Journal of Sensor Science and Technology
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• v.30 no.3
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• pp.170-174
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• 2021

As the rising attention to the medical and healthcare issue, Bio-MEMS (Micro electro mechanical systems) platform such as bio sensor, cell culture system, and microfluidics device has been studied extensively. Bio-MEMS platform mostly has high resolution structure made by biocompatible material such as polydimethylsiloxane (PDMS). In addition, three dimension structure has been applied to the bio-MEMS. Lithography can be used to fabricate complex structure by multiple process, however, non-rectangular cross section can be implemented by introducing optical apparatus to lithography technic. X-ray lithography can be used even for sub-micron scale. Here in, we demonstrated lines with round shape cross section using the tilted gold absorber which was deposited on the oblique structure as the X-ray mask. This structure was used as a mold for PDMS. Molded PDMS was applied to the cell culture platform. Moreover, molded PDMS was bonded to flat PDMS to utilize to the sub-micro channel. This work has potential to the large area bio-MEMS.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.6
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• pp.1849-1876
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• 2022

Wireless Sensor Network (WSN) is considered as an integral part of the Internet of Things (IoT) for collecting real-time data from the site having many applications in industry 4.0 and smart cities. The task of nodes is to sense the environment and send the relevant information over the internet. Though this task seems very straightforward but it is vulnerable to certain issues like energy consumption, delay, throughput, etc. To efficiently address these issues, this work develops a cross-layer model for the optimization between MAC and the Network layer of the OSI model for WSN. A high value of duty cycle for nodes is selected to control the delay and further enhances data transmission reliability. A node measurement prediction system based on the Kalman filter has been introduced, which uses the constraint based on covariance value to decide the scheduling scheme of the nodes. The concept of duty cycle for node scheduling is employed with a greedy data forwarding scheme. The proposed Duty Cycle-based Greedy Routing (DCGR) scheme aims to minimize the hop count, thereby mitigating the energy consumption rate. The proposed algorithm is tested using a real-world wastewater treatment dataset. The proposed method marks an 87.5% increase in the energy efficiency and reduction in the network latency by 61% when validated with other similar pre-existing schemes.