• 산업경영시스템학회지
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• 제39권1호
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• pp.130-139
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• 2016

The purpose of this paper is to analyze the problems and the sources of defective products and draw improvement plans in a small plastic boat manufacturing process using TOC (Theory Of Constraints) and statistical analysis. TOC is a methodology to present a scheme for optimization of production process by finding the CCR (Capacity Constraints Resource) in the organization or the all production process through the concentration improvement activity. In this paper, we found and reformed constraints and bottlenecks in plastic boat manufacturing process in the target company for less defect ratio and production cost by applying DBR (Drum, Buffer, Rope) scheduling. And we set the threshold values for the critical process variables using statistical analysis. The result can be summarized as follows. First, CCRs in inventory control, material mix, and oven setting were found and solutions were suggested by applying DBR method. Second, the logical thinking process was utilized to find core conflict factors and draw solutions. Third, to specify the solution plan, experiment data were statistically analyzed. Data were collected from the daily journal addressing the details of 96 products such as temperature, humidity, duration and temperature of heating process, rotation speed, duration time of cooling, and the temperature of removal process. Basic statistics and logistic regression analysis were conducted with the defection as the dependent variable. Finally, critical values for major processes were proposed based on the analysis. This paper has a practical importance in contribution to the quality level of the target company through theoretical approach, TOC, and statistical analysis. However, limited number of data might depreciate the significance of the analysis and therefore it will be interesting further research direction to specify the significant manufacturing conditions across different products and processes.

• 한국산업보건학회지
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• 제10권1호
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• pp.58-73
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• 2000

Objectives : This study was performed to evaluate BTEX exposure to gas station service attendants and the critical affect of benzene and MtBE airborne concentration. Methods : the degree of exposure to airborne BTEX and MtBE was examined in the service attendants at seven gas stations across the country during a summer season. The TWAs(time-weighted averages) of atmospheric concentration of substances in personal and area samples, were calculated. The component ratio of BTEX and MtBE in the samples of bulk gasoline from each station studied was also measured. Results : The airborne concentrations of BTEX and MtBE showed a lognormal distribution and The TWA concentrations of benzene in personal samples from each station were 0.089 ppm - 0.18 ppm, and those of toluene were 0.097 ppm - 0.2 ppm. The average TWA concentrations of xylene and ethyl benzene was 0.03 ppm and 0.001 ppm, respectively. The TWA concentrations of MtBE were 0.4 ppm - 1.3 ppm. The volume concentrations of MtBE, toluene, ethyl benzene and xylene in the bulk gasoline samples were 3 - 7.4 %, 3 - 12 %, 0.64 % and 1.5 - 10 %, respectively. Conclusions : The benzene concentration was detected to exceed the ACGIH threshold benzene level of 0.5 ppm, in one of 74 personal and area samples. MtBE, a substitute for aromatic compounds such as benzene in gasoline, was found to bring about a greater chance of exposure to carcinogen, due to its high vapor pressure and carcinogenicity.

• The Korean Journal of Pain
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• 제33권4호
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• pp.318-325
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• 2020

Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a major side effect of anti-cancer drugs. Neurotensin receptors (NTSRs) are widely distributed within the pain circuits in the central nervous system. The purpose of this study was to determine the role of NTSR1 by examining the effects of an NTSR1 agonist in rats with CIPN and investigate the contribution of spinal serotonin receptors to the antinociceptive effect. Methods: Sprague-Dawley rats (weight 150-180 g) were used in this study. CIPN was induced by injecting cisplatin (2 mg/kg) once a day for 4 days. Intrathecal catheters were placed into the subarachnoid space of the CIPN rats. The antiallodynic effects of intrathecally or intraperitoneally administered PD 149163, an NTSR1 agonist, were evaluated. Furthermore, the levels of serotonin in the spinal cord were measured by high-performance liquid chromatography. Results: Intrathecal or intraperitoneal PD 149163 increased the paw withdrawal threshold in CIPN rats. Intrathecal administration of the NTSR1 antagonist SR 48692 suppressed the antinociceptive effect of PD 149163 given via the intrathecal route, but not the antinociceptive effect of intraperitoneally administered PD 149163. Intrathecal administration of dihydroergocristine, a serotonin receptor antagonist, suppressed the antinociceptive effect of intrathecally administered, but not intraperitoneally administered, PD 149163. Injecting cisplatin diminished the serotonin level in the spinal cord, but intrathecal or intraperitoneal administration of PD 149163 did not affect this reduction. Conclusions: NTSR1 played a critical role in modulating CIPN-related pain. Therefore, NTSR1 agonists may be useful therapeutic agents to treat CIPN. In addition, spinal serotonin receptors may be indirectly involved in the effect of NTSR1 agonist.

• 한국산림과학회지
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• 제109권2호
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• pp.202-210
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• 2020

본 연구는 일본잎갈나무 임분의 안정성을 고려한 임분밀도 관리의 적정 수준을 탐색하기 위해 수행하였다. 분석에 활용된 조사 표본점 259개소의 자료를 통해 임분밀도관리도를 개발하였고, 이를 이용하여 상대수확량지수(Relative yield index: Ry)와 형상비(Height-to-diameter ratio: H/D)간의 관계 구명을 통해 임분밀도 관리의 적정 수준을 찾고자 하였다. 추정된 임분밀도관리도의 설명력(R²)은 0.600으로 나타났다. 상대수확량지수와 세장목의 출현비율의 관계 분석 결과, 일정임분밀도 이상에 도달할 경우 세장목의 비율이 급격히 증가하였고, 해당 곡선에서의 상대수확량지수(Ry)의 임계값은 0.63으로 분석되었다. 본 연구의 결과는 풍해, 설해와 같은 자연적인 피해를 저감 할 수 있는 임분 관리 전략 수립과 경제림의 생산력 향상을 위한 임분 시업체계 개발에 기여할 것으로 사료된다.

• 한국가스학회지
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• 제21권5호
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• pp.77-82
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• 2017

노후화 된 공정설비와 공장의 규모 확대 등 유해화학물질 사용량이 증가하고 있으며, 2013년부터 지속적으로 누출에 의한 사고가 발생하는 것을 확인할 수 있다. 장외영향평가에서 누출에 대한 끝점 농도는 ERPG 2로 나타내며, 안전보건공단의 가이드에서 시간에 따라 7분 미만에서 10분의 AEGL 2, 7분 이상 25분 미만일 때는 30분의 AEGL 2값을 사용한다. 기준이 되는 끝점 농도가 시간에 따라 모호하게 사용되고 있어, 사고 발생 시 문제를 야기할 것으로 생각이 된다. 이에 본 연구에서 회귀곡선을 통해 1~10분 사이의 AEGL 값을 도출하고, 동 시간의 Probit function의 0% Lethality 데이터와 비교하였으며, AEGL 결과 값을 사용하여 보다 명확한 시간에 따른 독성누출 평가에 활용될 것으로 생각된다.

• 한국축산식품학회지
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• 제24권3호
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• pp.310-318
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• 2004

Eating quality is a reflection of consumer satisfaction, while beef quality grade describes carcass characteristics of chiller assessment which are largely influenced by production systems including breeding and feeding schemes. On the other hand, it should be emphasized that high palatability of beef is a function of production and processing components including breed, nutrition, animal handling, post-slaughter intervention and cookery. Numerous efforts have been made by Korean beef industry and research institutes to deliver high quality beef with which domestic beef consumers are satisfied. However, majority of studies have tended to focus on improvement of intramuscular fat content with little attention on its effect on consumer-based eating quality. Furthermore, there is very limited accessible information(if any) on relative importance of eating characteristics (eg, tenderness, juiciness and flavor intensity) to consumer satisfactory rate and palatability grade. On this regard, our recent results indicated, for example, that when m. longissimus was prepared by a thin-slice style BBQ, relative weightings of tenderness, juiciness and flavor intensity for consumer satisfactory rate were 0.4, 0.35 and 0.25, respectively. When eating quality was graded into 4 groups by a sum of tenderness, juiciness and flavor intensity after multiplying these coefficients, consumers responded that the palatability score for high quality beef should be higher than 79 points. Based on our recent experiments, the current report is intended to highlight relative importance of eating quality characteristics on consumer satisfactory rate, and threshold of eating quality grade. In addition, post-slaughter intervention techniques such as electrical stimulation and tenderstretch are given as examples of critical control points of palatability assurance program of Hanwoo beef.

• 한국전자파학회논문지
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• 제23권7호
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• pp.791-796
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• 2012

RF 리미터(limiter)는 원하지 않는 신호로부터 수신단을 보호하기 위해 사용되는 소자로서, 임계값 이상의 모든 입력신호에 대해 일정한 출력을 제공한다. 다이오드를 사용하는 RF 리미터는 작은 신호는 통과시키는 반면, 어떤 임계값 이상의 신호는 감쇄시켜서 전달한다. 현대의 레이더 시스템에서 수신기를 보호하기 위해 사용되는 RF 리미터는 새로운 간섭 위협이나 복잡한 전자파 환경의 도전으로부터 극복할 수 있는 절대 필요한 역할을 수행한다. 본 논문은 고출력 RF 리미터를 구현하기 위해 PIN 다이오드와 Limit 다이오드의 조합으로 구성된 회로를 제안한다. PIN 다이오드는 스위치의 격리도(isolation) 특성을 이용하는 것과 같이 다이오드의 격리도 특성을 이용하는 개념을 적용한다. S-대역에서 200 us 펄스폭을 갖는 2 kW RF 리미터를 개발하였다. 그 측정 결과는 예측한 값과 잘 일치함을 알 수 있다.

• 한국도로학회논문집
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• 제9권4호
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• pp.135-147
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• 2007

아스팔트 포장에서의 골재분리(segregation)는 혼합물 내의 굵은골재와 잔골재가 고르게 분포하지 않은 결과이며, 균열, 레블링(raveling), 박리(stripping)와 같은 조기 파손을 야기한다. 그러나 소성변형에 대한 골재분리의 효과는 아직까지 제대로 규명되지 못하고 있다. 본 연구에서 수행된 실험 및 분석 결과, 아스팔트 포장의 소성변형은 혼합물의 골재분리보다는 혼합물 내의 골재 구조에 더 큰 영향을 받음을 알 수 있었다. 또한 굵은골재의 체적이 증가함에 따라 혼합물의 소성변형 저항성은 증가하였다. 그러나 이러한 현상은 낮은 공극율을 갖는 혼합물에서는 잘 일치하였지만, 높은 공극율을 갖는 혼합물에서는 골재의 체적 증가 보다는 공극율 자체가 소성변형에 더 큰 영향을 줌을 알 수 있었다. 즉, 공극율 10%를 기준으로, 이를 초과하는 혼합물은 굵은 골재의 체적이 큼에도 불구하고 소성변형 저항성은 크게 감소함을 알 수 있었다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제22권2호
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• pp.129-143
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• 2022

Background: Patient-controlled analgesia (PCA) has been widely used as an effective medical treatment for pain and for postoperative analgesia. However, improper dose errors in intravenous (IV) administration of narcotic analgesics from a PCA infusion pump can cause patient harm. Furthermore, opioid overdose is considered one of the highest risk factors for patients receiving pain medications. Therefore, accurate delivery of opioid analgesics is a critical function of PCA infusion pumps. Methods: We designed a microbalance method that consisted of a closed acrylic chamber containing a layer and an oil layer with an electronic balance. A commercially available infusion analyzer (IDA-5, Fluke Co., Everett, WA, USA) was used to measure the accuracy of the infusion flow rate from a commercially available smart PCA infusion pump (PS-1000, UNIMEDICS, Co., Ltd., Seoul, Korea) and compared with the results of the microbalance method. We evaluated the uncertainty of the flow rate measurement using the ISO guide (GUM:1995 part3). The battery life, delay time of the occlusion alarm, and bolus function of the PCA pump were also tested. Results: The microbalance method was good in the short-term 2 h measurement, and IDA-5 was good in the long-term 24 h measurement. The two measurement systems can complement each other in the case of the measurement time. Regarding battery performance, PS-1000 lasted approximately 5 days in a 1 ml/hr flow rate condition without recharging the battery. The occlusion pressure alarm delays of PS-1000 satisfied the conventional alarm threshold of occlusion pressure (300-800 mmHg). Average accuracy bolus volume was measured as 63%, 95%, and 98.5% with 0.1 ml, 1 ml, and 2 ml bolus volume presets, respectively. A 1 ml/hr flow rate measurement was evaluated as 2.08% of expanded uncertainty, with a 95% confidence level. Conclusion: PS-1000 showed a flow accuracy to be within the infusion pump standard, which is ± 5% of flow accuracy. Occlusion alarm of PS-1000 was quickly transmitted, resulting in better safety for patients receiving IV infusion of opioids. PS-1000 is sufficient for a portable smart PCA infusion pump.

• 원예과학기술지
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• 제30권5호
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• pp.477-483
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• 2012

미량원소인 Cu 시비농도를 인위적으로 조절하여 '금향', '매향' 및 '설향' 딸기를 재배하면서 시비수준이 생장에 미치는 영향을 구명하였다. 또한 생육을 우수하게 유지할 수 있는 식물체의 Cu 한계농도를 밝혀 딸기 재배 시 영양장해를 진단할 수 있는 기초 자료로 활용될 수 있도록 하기 위하여 본 연구를 수행하였다. Cu 시비농도에 영향을 받은 세 종류 딸기 품종의 건물중에서 '금향'과 '매향'은 0.25mM-1.0mM 시비구 간, '설향' 딸기의 경우 0.25mM-3.0mM 시비구 간통계적인 유의차가 없었고, '설향'이 '금향'이나 '매향'보다 Cu 과다시비에 대한 내성이 강함을 알 수 있었다. Cu가 과다하게 시비되어 식물체의 흡수량이 증가하면 신엽에서 엽맥 간 황화현상이나 엽맥 사이에 직선형태의 황화현상이 그리고 하위엽에서는 잎 가장자리가 주황색으로 변하는 증상이 나타났다. 관비용액의 Cu 시비농도를 증가시켜도 세 종류 딸기의 식물체 내 P, K, Ca 및 Mg 함량은 뚜렷한 경향을 발견할 수 없었다. 미량원소 중 Cu 함량은 시비농도가 높아짐에 따라 식물체 내 함량이 직선적으로 증가하였으며, Fe 및 Mo 함량은 관비용액의 Cu 농도에 대한 반응이 뚜렷하지 않았고, 경향도 발견할 수 없었다. '금향', '매향' 및 '설향' 딸기의 최대생장량보다 10% 적은 생장량과 이 때의 식물체내 Cu 함량을 정상 생장을 위한 최대한계점으로 간주하면 '금향' $71.4mg{\cdot}kg^{-1}$, '매향' $57.9mg{\cdot}kg^{-1}$, 그리고 '설향' $74.81mg{\cdot}kg^{-1}$ 이하를 유지하도록 Cu 시비농도를 조절해야 한다고 판단하였다.