• Title/Summary/Keyword: critical studies

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Lung Organoid on a Chip: A New Ensemble Model for Preclinical Studies

  • Hyung-Jun Kim;Sohyun Park;Seonghyeon Jeong;Jihoon Kim;Young-Jae Cho
    • International Journal of Stem Cells
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    • v.17 no.1
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    • pp.30-37
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    • 2024
  • The lung is a complex organ comprising a branched airway that connects the large airway and millions of terminal gas-exchange units. Traditional pulmonary biomedical research by using cell line model system have limitations such as lack of cellular heterogeneity, animal models also have limitations including ethical concern, race-to-race variations, and physiological differences found in vivo. Organoids and on-a-chip models offer viable solutions for these issues. Organoids are three-dimensional, self-organized construct composed of numerous cells derived from stem cells cultured with growth factors required for the maintenance of stem cells. On-a-chip models are biomimetic microsystems which are able to customize to use microfluidic systems to simulate blood flow in blood channels or vacuum to simulate human breathing. This review summarizes the key components and previous biomedical studies conducted on lung organoids and lung-on-a-chip models, and introduces potential future applications. Considering the importance and benefits of these model systems, we believe that the system will offer better platform to biomedical researchers on pulmonary diseases, such as emerging viral infection, progressive fibrotic pulmonary diseases, or primary or metastatic lung cancer.

Rethinking of Research and Educational Trends in Foreign Studies Field in Korea (한국에서의 해외지역 연구와 교육에 대한 비판적 고찰)

  • Kwon, Se Eun
    • Cross-Cultural Studies
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    • v.22
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    • pp.279-301
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    • 2011
  • This paper is aimed to examine the current research and educational problems of foreign studies in Korean universities and review some alternative ways. Area studies as foreign studies have several characteristics which are different from those of the other research disciplines. It is a research and educational program that promotes comprehensive understanding about political, economic, social, and cultural phenomena of a specific area in the world. For better understand 'others', researchers in the field of area studies must explain the whole mechanism of the area, which could be revealed in terms of the very existence of its reality. Foreign studies are accomplished with joint-research method, collaborating two or more different research disciplines and based on the contemporary system of knowledge accumulation and educational program. Therefore, the critical issue can be gradually taken on a political and social characteristic. At this point, research and educational manner in foreign studies field in Korea should be changed to secure the academic reflections of temporality, sociality, placeness using a new paradigm such as complexity.

Comparison of Domestic and International Research (1992-2011): Intensive Care Nursing Studies (국내·외 중환자간호 연구의 동향 분석: 양적 연구를 중심으로)

  • Choi, Eun Hee;Jang, Eun Hee;Choi, Ji Youn;Lee, So Jung;Seo, Hyo Kuyng;Park, Kyung Sook
    • Korean Journal of Adult Nursing
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    • v.27 no.4
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    • pp.384-396
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    • 2015
  • Purpose: The purpose of this study was to describe the approaches, methods and questions asked in intensive care unit studies published in Korean journals and the American Journal of Critical Care (AJCC) from 1992 to 2011. Only quantitative studies were reviewed. Methods: A total of 144 studies published in four Korean Journals and 521 studies published in American Journal of Critical Care (AJCC) were analyzed using descriptive statistics. Results: The most frequently used research design reported in Korean journals were surveys (83.5%), protocol development (10.1%), and randomized controlled trials (6.2%). In AJCC, the most frequently reported design was survey research (90.4%) and randomized controlled trials (16.1%). The most frequent nursing intervention reported in the AJCC was tube care (10.8%), and in Korean journals the intervention of suctioning (10.8%). In Korea, nurses were more likely to study instrument measurements (31.0%) and positioning (13.5%). In reported studies in the AJCC there were more reports on emotional support, exercise, and measurement research. Conclusion: There is overlap in the type of studies between the two countries in term of study design, whereas the types of nursing problems studied differed in United States and Korea. The result suggests that there were gaps and those more diverse studies and physiological measurements are needed.

Critical Review of Simulation Training's Effects on Nursing Students (간호학생을 대상으로 한 시뮬레이션 실습 효과에 대한 비판적 고찰)

  • Choi, Eun Hee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.5
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    • pp.141-149
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    • 2020
  • This study was undertaken to analyze the intervening effect of nursing simulation among nursing students. This was a critical review study, and data obtained were reviewed using various data bases, including RISS, KISS, NDSL, DBpia, and KRI. The terminologies entered in the data base were nursing and simulation. Selected studies were assessed for methodological quality; and narrative, descriptive or one group post-test studies were excluded from the analysis. Ed. Notes: Please review for accuracy. I have suggested the edit to the best of my understanding. Finally, 234 studies were included for investigation. Results included studies of nursing simulation intervention in Korea, commencing from 2008. One group pre-post test and two group post test were more designed in journals comparing to master thesis or doctoral dissertation. Clinical practice was the most frequently studied aspect by both the assessor and student in the two groups' pre-post test design. Nursing competences associated with dependent variables during simulation were integrated skills, critical thinking, communication, cooperation, professional recognition and leadership. The two groups pre-post design explored more varied competences as compared to other designs. Considering the results obtained, we conclude that simulation intervention is an effective teaching method for nursing students to help improve their clinical practice. However, further studies are required to assess the impact of critical thinking and problem solving.

Lost in Cultural Studies: Searching for an Exit in Drama/Theatre/Performance Studies (문화연구에서 길을 잃다: 한 드라마 연구자의 출구 찾기)

  • Choi, Sung Hee
    • Cross-Cultural Studies
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    • v.21
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    • pp.189-211
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    • 2010
  • The purpose of this paper is to 1)examine the current state of cultural studies in Korea with a focus on recent discourses about its 'crisis' and 2)attempt to find some ways out of these dilemmas in drama/theatre/performance studies. As Raymond Williams redefined 'culture' as 'a whole way of life,' performance studies has expanded the boundary of 'performance' from traditional performing arts onto almost everything that can be studied and analyzed 'as' performance. Performance is not only the final product on display but a whole process that includes training, workshop, and rehearsal of culture. According to Richard Schechner, workshop and rehearsal are the most critical and creative 'liminal' phases that allow traditional knowledge and alternative challenges to coexist in conflict and intentionally delay the final decision by putting itself in a perpetual process. From this view, this essay attempts to find an-no matter how limited and temporary-answer to or a possible exit from political and theoretical aporias of cultural studies.

A Study on the Critical Success Factors of Wireless Broadband Service (휴대인터넷(WiBro) 서비스의 주요성공요인에 관한 연구)

  • Yoon, Jong-Soo
    • Journal of the Korea Society of Computer and Information
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    • v.14 no.11
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    • pp.233-245
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    • 2009
  • The number of subscribers and the level of service usage are moderately low though WiBro service, as a new mobile Internet service, has been provided to mobile Internet users since June 2006. Considering this situation, the study was to identify, in exploratory point of view, which critical success factors are considered by mobile Internet users as the most important one to facilitate WiBro service, and to examine the perception of critical success factors of WiBro service varies according to their demographic characteristics. The study also was to suggest a few of research propositions on the relationships between critical success factors of WiBro service and characteristics of mobile Internet users, based on various statistical analyses. To accomplish these research purposes, the study defined research variables such as demographic characteristic of mobile Internet users, types of user, and critical success factors of WiBro service based on the review of mobile Internet service related studies. And then, the study performed various statistical analyses using survey questionnaires on mobile Internet users. The analyses show that there are little differences in perception on critical success factors of WiBro service among the mobile Internet users grouped by job and residential region, and that only the relationship between occupation of mobile Internet users and critical success factors of WiBro service is moderated by the types of user. Finally, the study proposed some research propositions, based on these analysis results, that could be used in the future studies.

Clinical characteristics of patients with the hardware failure after surgical stabilization of rib fractures in Korea: a case series

  • Na Hyeon Lee;Sun Hyun Kim;Seon Hee Kim;Dong Yeon Ryu;Sang Bong Lee;Chan Ik Park;Hohyun Kim;Gil Hwan Kim;Youngwoong Kim;Hyun Min Cho
    • Journal of Trauma and Injury
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    • v.36 no.3
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    • pp.196-205
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    • 2023
  • Purpose: Surgical stabilization of rib fractures (SSRF) is widely used in patients with flail chests, and several studies have reported the efficacy of SSRF even in multiple rib fractures. However, few reports have discussed the hardware failure (HF) of implanted plates. We aimed to evaluate the clinical characteristics of patients with HF after SSRF and further investigate the related factors. Methods: We retrospectively reviewed the electronic medical records of patients who underwent SSRF for multiple rib fractures at a level I trauma center in Korea between January 2014 and January 2021. We defined HF as the unintentional loosening of screws, dislocation, or breakage of the implanted plates. The baseline characteristics, surgical outcomes, and types of HF were assessed. Results: During the study period, 728 patients underwent SSRF, of whom 80 (10.9%) were diagnosed with HF. The mean age of HF patients was 56.5±13.6 years, and 66 (82.5%) were men. There were 59 cases (73.8%) of screw loosening, 21 (26.3%) of plate breakage, 17 (21.3%) of screw migration, and seven (8.8%) of plate dislocation. Nine patients (11.3%) experienced wound infection, and 35 patients (43.8%) experienced chronic pain. A total of 21 patients (26.3%) underwent reoperation for plate removal. The patients in the reoperation group were significantly younger, had fewer fractures and plates, underwent costal fixation, and had a longer follow-up. There were no significant differences in subjective chest symptoms or lung capacity. Conclusions: HF after SSRF occurred in 10.9% of the cases, and screw loosening was the most common. Further longitudinal studies are needed to identify risk factors for SSRF failure.

Effect of Metal Oxide of Ceramic Superconductor for Neutron beam Irradiation (중성자 조사용 전기도체의 첨가물 효과)

  • Lee, Sang-Heon;Choi, Yong
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.57 no.3
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    • pp.429-432
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    • 2008
  • Much studies have been concentrated to develop the fabrication technique for high critical current density but still there are a lot of gap which should be overcome for large scale application of superconducting materials at liquid nitrogen temperature. The improvement of the critical current can be achieved by forming the nano size defect working as a flux pinning center inside the superconductor. In this paper, the establishment of fabrication condition and additive effects of second elements were examined so as to improve the related properties to the practical use of superconductor.

Customer Satisfaction on Internet Commerce vs. TV Home Shopping (인터넷 상거래와 TV 홈쇼핑에서의 고객만족 비교)

  • 이정섭;장시영
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 2001.10a
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    • pp.180-183
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    • 2001
  • Direct marketing in the form of Internet Commerce and TV Home Shopping became the focus of concern for Korean companies. Despite the importance of research in these interactive systems, few studies have been performed on the consumer behavior in TV Home Shopping. This study explores what factors consumers perceive critical in these interactive systems, and analyzes the difference in consumer perception with respect to these critical factors.

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EXISTENCE OF PERIODIC SOLUTIONS WITH PRESCRIBED MINIMAL PERIOD FOR A FOURTH ORDER NONLINEAR DIFFERENCE SYSTEM

  • LIU, XIA;ZHOU, TAO;SHI, HAIPING
    • Journal of applied mathematics & informatics
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    • v.36 no.5_6
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    • pp.491-504
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    • 2018
  • In this article, we consider a fourth order nonlinear difference system. By making use of the critical point theory, we obtain some new existence theorems of at least one periodic solution with minimal period. Our main approach used in this article is the variational technique and the Saddle Point Theorem.