• 제목/요약/키워드: critical means

검색결과 975건 처리시간 0.022초

Customer Satisfaction Measurement Model Based on QFD

  • Liu, Yumin;Xu, Jichao
    • International Journal of Quality Innovation
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    • 제4권2호
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    • pp.101-122
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    • 2003
  • With the development of the American Customer satisfaction index (ACSI), research on customer satisfaction measurement or evaluation methods have become significant in the last decade. Most of international customer satisfaction barometers or indices are evolved based on the cause and effect relationship model of ACSI. Of critical importance to validity of customer satisfaction indices is how to construct a measurement attribute or indicator model and provide an effective implementation method effectively. Quality Function Deployment (QFD) is a very useful tool for translating the customer voice into product design through quality engineering. In fact, this is a methodology for measuring and analyzing evaluation indicators by their relationship matrix. In this paper, we will make an effort to integrate the framework of QFD into the measurement problem of customer satisfaction, and also develop a new multi-phase QFD model for evaluation of Customer Satisfaction Index (CSI). From the houses of quality in this model, the evaluation indicators impacting on customer's global satisfaction are identified by means of their relationship matrix. Then the evaluation indicator hierarchy and its measurement method for the customer satisfaction index are presented graphically. Furthermore, survey data from the Chinese automobile maintenance sector and a relevant case study are utilized to show the implementation method of the QFD model used to measure and analyze of customer satisfaction.

Osteoclast Activity and Osteoporosis

  • Kim, Hong-Hee
    • 한국응용약물학회:학술대회논문집
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    • 한국응용약물학회 2001년도 춘계학술대회
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    • pp.103-112
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    • 2001
  • Bone homeostasis is maintained by a balance between activities of osteoblasts(bone forming cells) and osteoclasts (bone resorbing cells). The activities of these cells are closely regulated by multiple factors including hormones and cytokines. The cessation of estrogen at menopause disrupts the balanced regulation and is the main cause of osteoporosis in postmenopausal women. Recent molecular biological studies led to a discovery of tumor necrosis factor(TNF) and TNF receptor families genes that play critical roles in the regulation of osteoclast formation and function. RANKL (receptor activator of nuclear factor kappa B ligand; also called ODF, TRANCE, and OPGL) expressed on cells supporting osteoclast is essential for osteoclast differentiation, activation, and survival. RANK, the counter-receptor for RANKL, is expressed on progenitor and mature osteoclasts. The interaction between RANKL and RANK is requlated by a soluble decoy receptor OPG (osteoprotegerin). Gene knock out studies of these molecules showed profound effects on bone. These results prompted development of new strategies for treatment of bone diseases. Inhibition of osteoclast activity by blocking the RANKL-RANK interaction using OPG is being attempted. Research on the signaling pathways of RANK is also actively carried out. Screening natural products that inhibit the RANKL-RANK interaction or the activity of obteoclasts would be another effective means to a new drug target for bone resorbing diseases.

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Use of DNA-Specific Anthraquinone Dyes to Directly Reveal Cytoplasmic and Nuclear Boundaries in Live and Fixed Cells

  • Edward, Roy
    • Molecules and Cells
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    • 제27권4호
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    • pp.391-396
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    • 2009
  • Image-based, high-content screening assays demand solutions for image segmentation and cellular compartment encoding to track critical events - for example those reported by GFP fusions within mitosis, signalling pathways and protein translocations. To meet this need, a series of nuclear/cytoplasmic discriminating probes have been developed: DRAQ5$^{TM}$ and CyTRAK Orange$^{TM}$. These are spectrally compatible with GFP reporters offering new solutions in imaging and cytometry. At their most fundamental they provide a convenient fluorescent emission signature which is spectrally separated from the commonly used reporter proteins (e.g. eGFP, YFP, mRFP) and fluorescent tags such as Alexafluor 488, fluorescein and Cy2. Additionally, they do not excite in the UV and thus avoid the complications of compound UV-autofluorescence in drug discovery whilst limiting the impact of background sample autofluorescence. They provide a convenient means of stoichiometrically labelling cell nuclei in live cells without the aid of DMSO and can equally be used for fixed cells. Further developments have permitted the simultaneous and differential labelling of both nuclear and cytoplasmic compartments in live and fixed cells to clearly render the precise location of cell boundaries which may be beneficial for quantitative expression measurements, cell-cell interactions and most recently compound in vitro toxicology testing.

자기유변유체를 이용한 반능동형 스퀴즈 필름 댐퍼의 해석 및 회전체 불균형 응답 제어 (Analysis of Magneto-rheological Fluid based Semi-active Squeeze Film Damper and Its Application to Unbalance Response Control of Rotor)

  • 김근주;이종원
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2004년도 추계학술대회논문집
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    • pp.1005-1011
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    • 2004
  • Squeeze film dampers (SFDs) have been commonly used to effectively enhance the dynamic behavior of the rotating shaft supported by rolling element bearings. However, due to the recent trends of high operating speed, high load capacity and light weight in rotating machinery, it is becoming increasingly important to change the dynamic characteristics of rotating machines in operation so that the excessive vibrations, which may occur particularly when passing through critical speeds or unstable regions, can be avoided. Semi-active type SFDs using magneto-rheological fluid (MR fluid), which responds to an applied magnetic field with a change in rheoloaical behavior, are introduced in order to find its applications to rotating machinery as an effective device attenuating unbalance responses. In this paper, a semi-active SFD using MR fluid is designed, tested and identified by means of linear analysis to investigate the capability of changing its dynamic properties such as damping and stiffness. Furthermore, the proposed device is applied to a rotor system to investigate its potential capability for vibration attenuation: an efficient method for selecting the optimal location of the proposed damper is introduced and control algorithm that could improve the unbalance response properties of a flexible rotor is also proposed.

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섬유강화 복합재료의 인장 및 굽힘에 의한 파괴 (Fracture Behavior of Fiber Reinforced Composites under tensile and Bending Loadings)

  • 남기우;문창권
    • 수산해양기술연구
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    • 제30권1호
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    • pp.45-52
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    • 1994
  • The study was conducted to evaluate reliability of the longitudinal tensile properties of unidirectional carbon fiber reinforced composites. Two kinds of carbon fiber reinforced composites laminates were tested in order to examine the factors of variability and have the information concerning reliability improvement. Temperature dependence of the strength and its variability were investigated by means of testing at two kinds of temperatures. Statistical distributions of the respective mechanical properties were obtained from the tensile tests. As a result, strength of composites was directly proportional to the ultimate strain and was not proportional to the elastic modulus. The fracture behavior in bending of notched plate was studied for a composite material. The uniform bending tests of notched plates have been carried out for a wide range of notch radii. The experiment shows that the nominal stress at failure decreased with decreasing notch radius and it approaches a constant value when the notch radius is less than about 0.3mm. The critical maximum stress is governed by notch root radius alone in the case of a constant thickness of specimen.

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전자기록 환경에서의 '업무친화적' 기록관리 방향성 분석 (A Critical Approach to 'Business-Friendly' Record Management In Electronic Records Environment)

  • 김명훈
    • 정보관리연구
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    • 제38권4호
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    • pp.145-166
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    • 2007
  • 본고에서는 전자기록 환경에서의 기록관리 패러다임 변화에 대한 한 단면으로서, '업무친화적' 기록 관리의 향방에 대해 논의하고자 한다. 우선 전자기록 환경의 특성을 기반으로 업무와 기록, 기록관리의 상관관계를 심층적으로 분석한 다음, 전자기록 환경에서 기록관리가 지니게 되는 의미 및 역할의 방향성을 제시코자 한다. 이를 통해 본고에서는 종래의 라이프사이클 체제하에서 간과되어 왔던 현용기록관리의 의의 및 역할을 전자기록 환경에서 재정립함과 더불어, 나아가 기록관리와 정보관리의 연계를 위한 이론적 기반을 제공할 것이다.

STATCOM을 이용한 지역간 융통전력 증대방안에 관한 연구 (A Study on Enhancement Available Transfer Capability Using STATCOM)

  • 김양일;정성원;신운용;곽상운;김재현
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2004년도 하계학술대회 논문집 A
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    • pp.156-158
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    • 2004
  • Recently electrical industry has been rapidly restructured by deregulation in the developed countries. The voltage stability problem of a power system is associated with a rapid voltage drop due to heavy load and it occurs because of inadequate reactive power supply at some critical buses. More effective power system control means for line flow and bus voltage are required for applying FACTS. In this paper Jacobian method used to study on the voltage stability, The Jacobian method is to check the eigenvalue of the load flow Jacobian matrix. If the power system is unstable, one of the eigenvalues, at leasL has crossed the imaginary axis. This paper demonstrate enhancement of ATC by application of STATCOM at WSCC 9-bus system.

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Experimental study of Kaiser effect under cyclic compression and tension tests

  • Chen, Yulong;Irfan, Muhammad
    • Geomechanics and Engineering
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    • 제14권2호
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    • pp.203-209
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    • 2018
  • Reliable estimation of compressive as well as tensile in-situ stresses is critical in the design and analysis of underground structures and openings in rocks. Kaiser effect technique, which uses acoustic emission from rock specimens under cyclic load, is well established for the estimation of in-situ compressive stresses. This paper investigates the Kaiser effect on marble specimens under cyclic uniaxial compressive as well as cyclic uniaxial tensile conditions. The tensile behavior was studied by means of Brazilian tests. Each specimen was tested by applying the load in four loading cycles having magnitudes of 40%, 60%, 80% and 100% of the peak stress. The experimental results confirm the presence of Kaiser effect in marble specimens under both compressive and tensile loading conditions. Kaiser effect was found to be more dominant in the first two loading cycles and started disappearing as the applied stress approached the peak stress, where felicity effect became dominant instead. This behavior was observed to be consistent under both compressive and tensile loading conditions and can be applied for the estimation of in-situ rock stresses as a function of peak rock stress. At a micromechanical level, Kaiser effect is evident when the pre-existing stress is smaller than the crack damage stress and ambiguous when pre-existing stress exceeds the crack damage stress. Upon reaching the crack damage stress, the cracks begin to propagate and coalesce in an unstable manner. Hence acoustic emission observations through Kaiser effect analysis can help to estimate the crack damage stresses reliably thereby improving the efficiency of design parameters.

인정투쟁: 한국노동운동과 경계에 선 사람들 (Struggle for Social Recognition in Labour Movement)

  • 유범상
    • 산업노동연구
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    • 제23권1호
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    • pp.165-195
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    • 2017
  • 본 논문은 부조리한 삶의 경계에 선 사람들을 인정투쟁의 관점에서 다룬다. 경계인은 1970년대부터 노동운동에 뛰어 든 사람들이다. 그리고 인정투쟁은 사랑, 권리, 가치부여의 측면에서 사회구성원으로부터 인정받기 위한 투쟁이다. 본 논문은 이들이 인정을 위한 열정으로부터 좌절된 과정을 분석한다. 경계인들은 인정을 위해 민주노조를 건설했고, 진보정당으로 결실을 맺었다. 그런데 부조리한 세상에 맞섰던 사람들은 개혁과 혁명의 경계인에서 무기력과 우울증이라는 갈림길에 있다. 열정이 식고 우울증의 현상이 심화되고 있는 이유는 무엇인가? 본 논문은 혁명을 꿈꾸면서 의인이었던 이들이 인정되지 못하고 여전히 밖에서 경계인이 되고 좌절과 무기력에 있는 핵심적인 이유로 내부와 외부와의 다양한 측면에서 균열을 지적했고 이를 극복하기 위해 균열을 극복하기 위한 소통을 대안으로 제시했다.

Resiliency Assessment of Sarasota Bay Watershed, Florida

  • 이혜경
    • 한국BIM학회 논문집
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    • 제9권1호
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    • pp.32-41
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    • 2019
  • As population in Sarasota and Manatee Counties, Florida in the United States is projected to increase, land use changes from land development happen continuously. The more land development means the more impervious surfaces and stormwater runoff to Sarasota Bay, which causes critical impact on the resiliency of the ecosystem. In order to decrease its impact on water quality and the ecosystem function of Sarasota Bay, it is important to assess the resilient status of communities that create negative impacts on the ecosystem. Three types of guiding principles of resiliency for Sarasota Bay watershed are suggested. To assess resiliency status, three indexes - vulnerability index, socio-economic index, and ecological index are developed and analyzed by using geographic information system for each census tract in the two counties. Since each indicator for vulnerability index, socio-economic index, and ecological index is measured with different metrics, statistical standardizing method - distance from the best and worst performers is used for this study to directly compare and combine them all to show total resilience score for each census tract. Also, the ten most and the ten least scores for the total resilience index scores are spatially distributed for better understanding which census tracts are most or least resilient. As Sarasota Watershed boundary is also overlaid, it is easy to understand how each census tract attains its resilience and how each census tract impacts to Sarasota Bay ecosystem. Based on results of the resiliency assessment several recommendations, guidelines, or policies for attaining or enhancing resiliency are suggested.