• Title/Summary/Keyword: critical evidence

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Association of COVID-19 vaccine attitudes and cognitions of COVID-19-related stigma with vaccine hesitancy among college students

  • Kim, Ji-Soo
    • The Journal of Korean Academic Society of Nursing Education
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    • v.28 no.3
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    • pp.296-304
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    • 2022
  • Purpose: This study aimed to examine the association of COVID-19 vaccine attitudes and cognitions of COVID-19-related stigma with vaccine hesitancy among college students. Methods: This cross-sectional study using a web-based survey was conducted with 242 college students in April 2021 before Korea's national COVID-19 vaccination program had begun. Data were analyzed using multinominal logistic regression analyses. Results: Of the participants who were unsure of their intention to receive the COVID-19 vaccine, 66.0% had less experience with flu vaccinations and were 1.43 times more likely to report a mistrust of vaccine benefits (OR=1.43, CI=1.22, 1.68). Those with no intention of receiving the vaccine were 25.0% less likely to be aware of COVID-19 stigma (OR=0.75, CI=0.65, 0.86), 2.08 times more likely to mistrust vaccine benefits (OR=2.08, CI=1.62, 2.68), and 1.53 times more likely to worry about an unforeseen future negative side effects from vaccination (OR=1.53. CI=1.16, 2.00). Conclusion: Nurses could play an important role in educating college students about vaccination benefits, including reviewing vaccines' side effects with evidence, to reduce vaccine hesitancy. College students who have less empathy for others regarding COVID-19 infection might have higher COVID-19 vaccine hesitancy. Accordingly, explaining to students the necessity of their vaccination in preventing transmission to the surrounding community and vulnerable populations is critical.

Determining Dimensions of Job Satisfaction among Employees: Evidence from Commercial Bank Industries in Bangladesh

  • Md. Sayed, UDDIN;Md. Atikur, RAHAMAN;Wasib Bin, LATIF
    • The Journal of Asian Finance, Economics and Business
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    • v.10 no.2
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    • pp.195-201
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    • 2023
  • Since the banking industry relies so heavily on strong customer-staff interactions, measuring employee job satisfaction has become a critical problem. To achieve benefits for both individuals and organizations, it is crucial to foster and ensure employee job satisfaction. The main objective of this study is to determine the influencing factors of employees' job satisfaction in commercial banks in Bangladesh. This study focused on some significant factors such as employee empowerment, job security, management support, and attractive compensation in an organization. In terms of research purpose, non-probability convenience sampling has been used, and the study is quantitative in nature. For data collection purposes, an online survey questionnaire was prepared based on previously published articles. The targeted population was the bank employees of commercial banks in Bangladesh where the final sample size was n = 200. For analyzing the collected data, SPSS 26.0 version has been used to test the study model and the proposed hypotheses. This study also shows that employee empowerment, job security, management support, and attractive compensation have positive and significant effects on employees' job satisfaction at the workplace. Finally, this study has offered some extraordinary directions and implications for future research on commercial bank authorities in Bangladesh.

The Relationship between Employees' ESG Perception and Service Quality: A Multi-level Analysis in the Korean Parcel Delivery Industry (조직 구성원의 기업 ESG 인식과 서비스 품질: 택배 서비스를 대상으로 한 다수준 분석)

  • Lee, Su-Yol;Park, JaeHeum
    • Journal of Korean Society for Quality Management
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    • v.50 no.3
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    • pp.407-424
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    • 2022
  • Purpose: This study examines the relationship between the environment, society, and governance (ESG) perception of service providers and service quality by considering job satisfaction as a mediator in the Korean parcel delivery context. Methods: This study uses a multi-level analysis by incorporating organizational and individual levels of analysis. It employs a survey method for measuring the ESG perception of parcel delivery persons and service quality ratings from the Korean government. A hierarch regression analysis with 241 responses was used to test hypotheses. Results: The results of this study provide evidence that the ESG perception, particularly its social dimension, of parcel delivery persons is positively associated with service quality. This study also finds the positive effect of the ESG perception on job satisfaction. However, the mediating effect of job satisfaction between the ESG perception and service quality was not confirmed. Conclusion: This study presents significant implications for scholars and practitioners. Parcel delivery companies should implement relevant ESG activities and communicate them with their service persons to improve delivery service quality. The ESG perception of employees plays a critical role in the moment of truth in parcel service delivery to enhance customer satisfaction and service quality.

Intervention of Virtual Reality of Adult Nursing Practicum for Nursing Students: A Systematic Review (간호대학생의 성인간호실습 가상현실 교육 중재: 체계적 고찰)

  • Kim, Hyun Kyoung;Ko, Eun Jung
    • The Journal of the Convergence on Culture Technology
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    • v.8 no.6
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    • pp.373-380
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    • 2022
  • This study explored the effectiveness of virtual reality education interventions for nursing students in adult nursing practicum. This systematic review extracted intervention methods, research topics, outcome variables, and evidence synthesis of effectiveness. Seven studies were extracted from the databases of PubMed, Cochrane Library, EMBASE, and RISS. This study showed effects on knowledge, performance, attitude, critical thinking, self-efficacy, information assessment ability, problem-solving ability, self-confidence, and efficiency of nursing students. Therefore, virtual reality educational intervention contribute to enhance the competencies in adult nursing practicum.

The Necessity of Sports Leadership for Business Leaders

  • LEE, Jae-Hyung
    • East Asian Journal of Business Economics (EAJBE)
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    • v.10 no.3
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    • pp.115-125
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    • 2022
  • Purpose - Sports leadership is frequently used as a useful comparison for understanding traits like teamwork and motivation in the business world. Based on the results of numerous studies, this research provides a critical assessment of the current state of knowledge in sport leadership research using methodological advances from other disciplines such as business and economics Research design, Data, and methodology - This research selected the systematic review analysis as its research design. The review analysis is a minimal set of elements for reporting in reviews by evidence. The present author included numerical data with confidence ranges for the most crucial outcomes if the review contained meta-analyses. Result - According to a study in sports, transformational leadership has a positive effect on company success. Communication and commitment, two possible mediators, may strengthen the impact of transformational leadership on cohesiveness. Prior researchers found that intrinsic drive serves as a bridge between transformational leadership and performance. Conclusion - This research concludes that the articles used for data analysis in this study examined the value of sports leadership for business leaders in a number of sports, including athletics and handball, among others. There is a good chance that different sports will provide different insights on the value of sports leadership for CEOs.

Signaling Role of NADPH Oxidases in ROS-Dependent Host Cell Death Induced by Pathogenic Entamoeba histolytica

  • Lee, Young Ah;Sim, Seobo;Kim, Kyeong Ah;Shin, Myeong Heon
    • Parasites, Hosts and Diseases
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    • v.60 no.3
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    • pp.155-161
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    • 2022
  • All living organisms are destined to die. Cells, the core of those living creatures, move toward the irresistible direction of death. The question of how to die is critical and is very interesting. There are various types of death in life, including natural death, accidental death, questionable death, suicide, and homicide. The mechanisms and molecules involved in cell death also differ depending on the type of death. The dysenteric amoeba, E. histolytica, designated by the German zoologist Fritz Schaudinn in 1903, has the meaning of tissue lysis; i.e., tissue destroying, in its name. It was initially thought that the amoebae lyse tissue very quickly leading to cell death called necrosis. However, advances in measuring cell death have allowed us to more clearly investigate the various forms of cell death induced by amoeba. Increasing evidence has shown that E. histolytica can cause host cell death through induction of various intracellular signaling pathways. Understanding of the mechanisms and signaling molecules involved in host cell death induced by amoeba can provide new insights on the tissue pathology and parasitism in human amoebiasis. In this review, we emphasized on the signaling role of NADPH oxidases in reactive oxygen species (ROS)-dependent cell death by pathogenic E. histolytica.

Buying Virtual Fashion Items in the Metaverse - Focusing on Self-Regulatory Focus - (메타버스 가상 패션아이템 구매 - 자기조절초점을 중심으로 -)

  • Soo-kyoung Ahn
    • Fashion & Textile Research Journal
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    • v.24 no.6
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    • pp.707-718
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    • 2022
  • The metaverse is emerging as the next digital environment for people not only to interact and collaborate with others, but also to have virtual consumption experiences. In this study, virtual fashion items for the consumer's digital self are deemed significant products with consumption value. Drawing from the regulatory focus theory, this study examines how consumers' promotion and prevention focus influence value perception and buying behaviors of virtual fashion items in the metaverse context. The data were collected through an online survey. A total of 546 consumers in their twenties who are aware of the metaverse responded to a self-administered questionnaire. The results showed that promotion focus influenced all the perceived consumption values of virtual fashion items such as the economic, visual authority, hedonic, and social value, whereas prevention focus influenced only the visual authority value. Visual authority value negatively affected both purchase intention and willingness to pay premium price, while others had a positive effect. The findings provide theoretical evidence that consumers' regulatory focus is critical in buying virtual fashion items and suggest that marketers devise effective strategies to stimulate consumers' regulatory focus and to emphasize the economic, hedonic, and social value of the items in the metaverse context.

CD4+ cytotoxic T cells: an emerging effector arm of anti-tumor immunity

  • Seongmin Jeong;Nawon Jang;Minchae Kim;Il-Kyu Choi
    • BMB Reports
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    • v.56 no.3
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    • pp.140-144
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    • 2023
  • While CD8+ cytotoxic T cells have long been considered the primary effector in controlling tumors, the involvement of CD4+ "helper" T cells in anti-tumor immunity has been underappreciated. The investigations of intra-tumoral T cells, fueled by the recent advances in genomic technologies, have led to a rethinking of the indirect role of CD4+ T cells that have traditionally been described as a "helper". Accumulating evidence from preclinical and clinical studies indicates that CD4+ T cells can acquire intrinsic cytotoxic properties and directly kill various types of tumor cells in a major histocompatibility complex class II (MHC-II)-dependent manner, as opposed to the indirect "helper" function, thus underscoring a potentially critical contribution of CD4+ cytotoxic T cells to immune responses against a wide range of tumor types. Here, we discuss the biological properties of anti-tumor CD4+ T cells with cytotoxic capability and highlight the emerging observations suggesting their more significant role in anti-tumor immunity than previously appreciated.

Anti-Ferroptotic Effects of Nrf2: Beyond the Antioxidant Response

  • Aryatara Shakya;Nicholas W. McKee;Matthew Dodson;Eli Chapman;Donna D. Zhang
    • Molecules and Cells
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    • v.46 no.3
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    • pp.165-175
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    • 2023
  • The transcription factor Nrf2 was originally identified as a master regulator of redox homeostasis, as it governs the expression of a battery of genes involved in mitigating oxidative and electrophilic stress. However, the central role of Nrf2 in dictating multiple facets of the cellular stress response has defined the Nrf2 pathway as a general mediator of cell survival. Recent studies have indicated that Nrf2 regulates the expression of genes controlling ferroptosis, an iron-and lipid peroxidation-dependent form of cell death. While Nrf2 was initially thought to have anti-ferroptotic function primarily through regulation of the antioxidant response, accumulating evidence has indicated that Nrf2 also exerts anti-ferroptotic effects via regulation of key aspects of iron and lipid metabolism. In this review, we will explore the emerging role of Nrf2 in mediating iron homeostasis and lipid peroxidation, where several Nrf2 target genes have been identified that encode critical proteins involved in these pathways. A better understanding of the mechanistic relationship between Nrf2 and ferroptosis, including how genetic and/or pharmacological manipulation of Nrf2 affect the ferroptotic response, should facilitate the development of new therapies that can be used to treat ferroptosis-associated diseases.

Vietnam and the Specter of Deglobalization

  • John Walsh
    • SUVANNABHUMI
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    • v.15 no.2
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    • pp.23-55
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    • 2023
  • Just as globalization has many aspects and has developed in various, sometimes contradictory ways with both positive and negative impacts, so too would the reverse process of deglobalization have wide-ranging effects for individuals, communities, and nations. Some parts of globalization began to fray during the coronavirus pandemic (e.g. failing supply chains and disarray in the global shipping industry). Deglobalization would bring about much more significant changes in focusing on local production and consumption, eschewing non-essential flights and international tourism, and replacing personal experience with virtual presence. These impacts would be particularly severe for Vietnam, since its government has placed intensive connectivity with global production at the center of its model for the rapid development on which much of its legitimacy rests and it has joined as many international, multilateral organizations, and protocols as it has been able to do. Through critical analysis of secondary data from a wide range of sources, this paper examines the motivations that people, institutions, and governments might have to pursue deglobalization and then seeks evidence for whether the changes that would bring have started to affect Vietnam. While it is difficult to be too certain about this while the pandemic continues, it is evident that pressures are building in the global north to reconfigure supply chains for greater security, to reduce carbon emissions through regulating long-distance exchanges, and to withdraw from personal contacts. It is argued that a focus on digitalization in economy and society will help to mitigate the negative effects of deglobalization on Vietnam, at least in the medium-term.