• 천문학회보
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• 제40권1호
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• pp.68.1-68.1
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• 2015

Gravitational collapse is a dynamical process associated with star formation. One observational evidence of such infall motion is so called "blue asymmetry" profile, which is the optically thick line profile with the intensity peak skewed blueward relative to the intensity peak of optically thin lines. We analyzed both HCN J=1-0 and HNC J=1-0 line profiles to study the inflow motion in different evolutionary stages of massive star formation; Infrared dark clouds (IRDCs), High-mass protostellar object (HMPOs), and Ultra-compact HII regions (UCHIIs). The infall asymmetry in the HCN spectra seems to be more prevalent than the HNC spectra throughout all the three evolutionary phases. The prevalence of the blue profile in the HCN spectra is found in every evolutionary stage, with IRDCs showing the largest blue excess. In the case of the HNC spectra, only IRDCs show the blue excess statistically significant. These results suggest that HCN may be a better infall tracer in massive star forming region. In addition, even though the characteristics of the blue profile largely depend on the suitable combination of optical depth and critical density, our analyses also indicate that IRDCs may have the most active infall process compared to other evolutionary phases.

• 한국게임학회 논문지
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• 제14권1호
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• pp.81-92
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• 2014

2011년 도입된 청소년보호법 제26조는 '인터넷게임중독'이 실재한다고 전제하여 인터넷게임에 대한 접근을 일정시간동안 제한하는 기술적 조치이다. 이 조항은 도입과 함께 헌법소원의 대상이 되었다. 이 제도는 기술에 대한 사회적 수용과 저항을 잘 보여주는 논쟁사례이다. 우리는 '인터넷게임중독'이라는 용어가 학술적으로 여전히 논쟁적임에도 불구하고 사회적으로 널리 사용될 수 있었던 배경을 진지하게 살펴볼 필요가 있다. 이 논쟁을 기술사회적 관점에서 분석함으로써 국가 주도적 기술도입이 불러온 기술혐오를 발견할 수 있다. 기술혐오에 대한 해법은 병리적 프레임 보다 기술에 대한 비판담론 프레임으로 극복해야 할 필요가 있다.

• IMMUNE NETWORK
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• 제11권5호
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• pp.227-244
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• 2011

MicroRNAs (miRNAs) are small noncoding RNA molecules that negatively regulate gene expression via degradation or translational repression of their target messenger RNAs (mRNAs). Recent studies have clearly demonstrated that miRNAs play critical roles in several biologic processes, including cell cycle, differentiation, cell development, cell growth, and apoptosis and that miRNAs are highly expressed in regulatory T (Treg) cells and a wide range of miRNAs are involved in the regulation of immunity and in the prevention of autoimmunity. It has been increasingly reported that miRNAs are associated with various human diseases like autoimmune disease, skin disease, neurological disease and psychiatric disease. Recently, the identification of miRNAs in skin has added a new dimension in the regulatory network and attracted significant interest in this novel layer of gene regulation. Although miRNA research in the field of dermatology is still relatively new, miRNAs have been the subject of much dermatological interest in skin morphogenesis and in regulating angiogenesis. In addition, miRNAs are moving rapidly center stage as key regulators of neuronal development and function in addition to important contributions to neurodegenerative disorder. Moreover, there is now compelling evidence that dysregulation of miRNA networks is implicated in the development and onset of human neruodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Tourette's syndrome, Down syndrome, depression and schizophrenia. In this review, I briefly summarize the current studies about the roles of miRNAs in various autoimmune diseases, skin diseases, psychoneurological disorders and mental stress.

• The Journal of Asian Finance, Economics and Business
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• 제7권12호
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• pp.515-521
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• 2020

Work motivation is critical for ensuring sustainability of any business firm. Motivated personnel essentially helps an organization achieve its organizational goal and objective. Hence, it has become an essential duty for business managers and management committees to identify the motivating factors that would strongly affect their employees. The purpose of the current research is to identify which are the factors that motivate service employees most at their workplace in Bangladesh. The study has used survey questionnaires to collect data from service employees. Convenience sampling is used for data collection. A total of 240 questionnaires were distributed and 183 completed questionnaires were returned (response rate: 77%). The study used purposeful motivating factors, which are ranked (from 1 to 10) by the service employees according to the significance of the factors. Mean value is applied to determine the most crucial motivating factor, where the factor with lowest mean value is considered as the highest significant motivating factor. Results reveal that job certainty, career growth and advancement opportunity, and quality working environment have been the most crucial and influential motivating factors for the service employees. The study adequately underlines the necessity of motivational factors and provides some guidelines to keep employees motivated.

• The Journal of Asian Finance, Economics and Business
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• 제7권12호
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• pp.33-42
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• 2020

The neoclassical economic supporters have suggested that foreign direct investment and raw material (e.g., coal, electricity, gas, and oil) are critical economic growth inputs. Few previous studies have analyzed the relationship between foreign direct investment and energy consumption on economic growth. However, existing studies usually have applied the frequentist inference. The limitation of the frequentist inference is that, if the coefficient of the independent variable is not yet significant, then conclusions might be unreliable. By applying the Bayesian approach, the main aim of this study is to revisit the impact of foreign direct investment, electricity consumption, and urbanization on economic growth in six ASEAN countries from 1980 to 2016. The obtained outcome shows that the impact of electricity consumption is evident and positive on economic growth in both frequentist and Bayesian inferences. However, the influence of foreign direct investment is not identified by frequentist inference, while Bayesian inference provides evidence that foreign direct investment is a moderately positive impact on economic growth. The empirical result from Bayesian inference contributes to the literature on foreign direct investment modeling and could be of significant importance for a more efficient foreign direct investment attracting and achieve sustainability in the long-term.

• 영어어문교육
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• 제16권1호
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• pp.41-59
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• 2009

The present study investigated Korean learners' knowledge on the range of possible interpretations of English locative PPs with manner of motion verbs, and considers whether learners can arrive at a superset L2 grammar on the basis of positive L2 input. Unlike Korean, some English locative PPs occurring with manner of motion verbs (such as in John jumped on the bed) are ambiguous as they can be interpreted as either directional or locational. Thirty Korean learners of English in three distinct groups (Advanced EFL-only group; Intermediate-EFL-only group; and ESL-experienced group) participated in an experimental study, along with a control group of nine native speakers of English. The results of the study showed that I) Korean learners, overall, tended to interpret English locative PPs as only locational, failing to recognize the ambiguity between the directional and locational readings in the target structure; 2) For the learners who experienced only the EFL context, even highly proficient learners, as well as intermediate level learners, failed to acknowledge the ambiguity; 3) The learners who experienced the ESL context for an extended period of time could identify the target reading to some extent, although they still could not reach the native-like competence. From these results, it is argued that robustness of positive evidence, not simply its availability, is critical in the acquisition of the superset L2 targets like the present one.

• 한국전산구조공학회논문집
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• 제24권6호
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• pp.637-643
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• 2011

본 논문에서는 결합 기반 페리다이나믹스 해석법을 사용하여 동적취성 파괴시뮬레이션을 수행하였다. 페리다이나믹스 모델은 분기 균열, 균열 불안정성, 균열 경로의 비대칭성, 연쇄 분기 균열, 2차 균열 전파 등 다양한 동적취성 파괴현상을 잘 해석해 낼 수 있다. 본 논문에서는 분기 균열의 분기 각도와 균열 전파속도에 대한 응력파의 영향에 대해 연구하였다. 극한 시점에 도달한 균열은 둘 이상으로 분기되어 전파되고 그 전파속도는 기존 균열의 전파속도와 크게 달라지지 않는다는 사실이 여러 실험을 통해서 입증이 되었다. 페리다이나믹스로 해석된 분기 균열은 실험을 통해 제안된 균열 전파현상들과 잘 부합되는 것을 확인할 수 있었다.

• 치위생과학회지
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• 제6권3호
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• pp.193-199
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• 2006

본 연구는 미국과 우리나라의 치위생 교육이념을 비교 분석하였다. 미국의 치위생 프로그램은 우리나라와 구별되는 이념적 특징으로서 치위생과정에 근거한 포괄적 치위생관리 능력, 표준적 수행능력, 비판적 사고와 문제해결 능력, 자율적 의사 결정 능력의 배양을 지향하고 있다. 또한 평생교육의 참여와 자기주도 학습을 수행할 수 있는 기초능력의 배양, 대인관계 및 의사소통 기술을 증진하고자 하는 교육이념을 표방하고 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5333-5338
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• 2012

Vitamin B6 functions as a coenzyme in >140 enzymatic reactions involved in the metabolism of amino acids, carbohydrates, neurotransmitters, and lipids. It comprises a group of three related 3-hydroxy-2-methyl-pyrimidine derivatives: pyridoxine (PN), pyridoxal (PL), pyridoxamine (PM) and their phosphorylated derivatives [pyridoxal 5'-phosphate (PLP) and pyridoxamine 5'-phosphate (PMP)], In the folate metabolism pathway, PLP is a cofactor for the mitochondrial and cytoplasmic isozymes of serine hydroxymethyltransferase (SHMT2 and SHMT1), the P-protein of the glycine cleavage system, cystathionine ${\beta}$-synthase (CBS) and ${\gamma}$-cystathionase, and betaine hydroxymethyltransferase (BHMT), all of which contribute to homocysteine metabolism either through folate-mediated one-carbon metabolism or the transsulfuration pathway. Folate cofactors carry and chemically activate single carbons for the synthesis of purines, thymidylate and methionine. So the evidence indicates that vitamin B6 plays an important role in maintenance of the genome, epigenetic stability and homocysteine metabolism. This article focuses on studies of strand breaks, micronuclei, or chromosomal aberrations regarding protective effects of vitamin B6, and probes whether it is folate-mediated one-carbon metabolism or the transsulfuration pathway for vitamin B6 which plays critical roles in prevention of cancer and cardiovascular disease.

• 생물정신의학
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• 제25권1호
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• pp.1-8
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• 2018

Insomnia is a common sleep-related symptom which occurs in many populations, however, the neural mechanism underlying insomnia is not yet known. The hyperarousal model explains the neural mechanism of insomnia to some extent, and the frontal cortex dysfunction has been known to be related to primary insomnia. In this review, we discuss studies that applied resting state and/or task-related functional magnetic resonance imaging to demonstrate the deficits/dysfunctions of functional activation and network in primary insomnia. Empirical evidence of the hyperarousal model and proposed relation between the frontal cortex and other brain regions in primary insomnia are examined. Reviewing these studies could provide critical insights regarding the pathophysiology, brain network and cerebral activation in insomnia and the development of novel methodologies for the diagnosis and treatment of insomnia.