• Genomics & Informatics
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• 제20권2호
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• pp.22.1-22.9
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• 2022

The rise of newer coronavirus disease 2019 (COVID-19) variants has brought a challenge to ending the spread of COVID-19. The variants have a different fatality, morbidity, and transmission rates and affect vaccine efficacy differently. Therefore, the impact of each new variant on the spread of COVID-19 is of interest to governments and scientists. Here, we proposed mathematical SEIQRDVP and SEIQRDV3P models to predict the impact of the Omicron variant on the spread of the COVID-19 situation in South Korea. SEIQEDVP considers one vaccine level at a time while SEIQRDV3P considers three vaccination levels (only one dose received, full doses received, and full doses + booster shots received) simultaneously. The omicron variant's effect was contemplated as a weighted sum of the delta and omicron variants' transmission rate and tuned using a hyperparameter k. Our models' performances were compared with common models like SEIR, SEIQR, and SEIQRDVUP using the root mean square error (RMSE). SEIQRDV3P performed better than the SEIQRDVP model. Without consideration of the variant effect, we don't see a rapid rise in COVID-19 cases and high RMSE values. But, with consideration of the omicron variant, we predicted a continuous rapid rise in COVID-19 cases until maybe herd immunity is developed in the population. Also, the RMSE value for the SEIQRDV3P model decreased by 27.4%. Therefore, modeling the impact of any new risen variant is crucial in determining the trajectory of the spread of COVID-19 and determining policies to be implemented.

• International Journal of Computer Science & Network Security
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• 제22권4호
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• pp.39-46
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• 2022

The spread of Omicron, a mutated version of COVID-19 across several countries is leading to the discussion of lockdown once again for curbing the spread of the new virus. In this context, this research is showing the impact of lockdown for the successful control of the COVID-19 pandemic in Saudi Arabia. The outbreak of the COVID-19 pandemic around the globe has affected Saudi Arabia with around 2,37,803 confirmed cases within the initial 4 months of transmission. Saudi Arabia has announced a 21-day lockdown from March 23, 2020, to reduce the transmission of the COVID-19 pandemic. Machine Learning-based, Multinomial logistic regression was applied to understand the relationship between daily COVID-19 confirmed cases and lockdown in the 17 most-affected cities of KSA. We used secondary published data from the Ministry of Health, KSA daily dataset of COVID-19 confirmed case counts. These 17 cities were categorized into 4 classes based on lockdown dates. A total of three scenarios such as night lockdown, full lockdown, and no lockdown have been analyzed with the total number of confirmed cases with 4 classes. 15 out of 17 cities have shown a strong correlation with a confidence interval of 95%. These findings provide evidence that the COVID-19 pandemic may be partially suppressed with lockdown measures.

• 한국융합학회논문지
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• 제13권5호
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• pp.165-172
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• 2022

2019년 12월 시작된 COVID-19로 전 세계는 코로나바이러스 팬데믹에 국제경제는 위기를 맞았다. 우리나라는 전국민 기본소득 지원, 소상공인 소득지원 등 다양한 방식으로 경기를 부양하기 위한 노력을 기울였지만 여전히 어려움이 컸다. 본 연구는 장기화된 COVID-19가 사회의 기본단위인 가족에게 그리고 각각의 가족구성원들에게 어떠한 영향을 미치는가를 살펴보는데 목적을 두고 있다. COVID-19에 따른 가족갈등 및 위기 해결방법은 가족에 대한 집중적 지원, 가구성원들간의 유대 중가를 위한 프로그램 지원, 그리고 평등한 가치관 인식이 가족갈등과 해체를 저지하고 가족의 붕괴를 막을 수 있을 것이라 생각한다.

• International Journal of Internet, Broadcasting and Communication
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• 제14권3호
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• pp.85-90
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• 2022

In this study, keywords from representative online portal sites such as NAVER, Google, and Youtube were collected based on text mining analysis technique using TEXTOM to check the changes in the restaurant industry before and after COVID-19. The collection keywords were selected as dining out, food service industry, and dining out culture. For the collected data, the top 30 words were derived, respectively, through the refinement process. In addition, comparative analysis was conducted by defining data from 2018 to 2019 before COVID-19, and from 2020 to 2021 after COVID-19. As a result, 8272 keywords before COVID-19 and 9654 keywords after COVID-19, a total of 17926 keywords, were derived. In order for the food service industry to develop after the COVID-19 pandemic, it is necessary to commercialize the recipes of restaurants to revitalize the distribution of home-use food products that replace home-cooked meals such as meal kits. Due to the social distancing caused by COVID-19, the dining out culture has changed and the trend has changed, and it has been confirmed that the consumption culture has changed to eating and delivering at home more safely than visiting restaurants. In addition, it has been confirmed that the consumption culture of existing consumers is changing to a trend of cooking at home rather than visiting restaurants.

• Journal of Ginseng Research
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• 제47권2호
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• pp.283-290
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• 2023

Hypercoagulability is frequently observed in patients with severe coronavirus disease-2019 (COVID-19). Platelets are a favorable target for effectively treating hypercoagulability in COVID-19 patients as platelet hyperactivity has also been observed. It is difficult to develop a treatment for COVID-19 that will be effective against all variants and the use of antivirals may not be fully effective against COVID-19 as activated platelets have been detected in patients with COVID-19. Therefore, patients with less severe side effects often turn toward natural remedies. Numerous phytochemicals are being investigated for their potential to treat a variety of illnesses, including cancer and bacterial and viral infections. Natural products have been used to alleviate COVID-19 symptoms. Panax ginseng has potential for managing cardiovascular diseases and could be a treatment for COVID-19 by targeting the coagulation cascade and platelet activation. Using molecular docking, we analyzed the interactions of bioactive chemicals in P. ginseng with important proteins and receptors involved in platelet activation. Furthermore, the SwissADME online tool was used to calculate the pharmacokinetics and drug-likeness properties of the lead compounds of P. ginseng. Dianthramine, deoxyharrtingtonine, and suchilactone were determined to have favorable pharmacokinetic profiles.

• The Journal of Korean Physical Therapy
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• 제34권6호
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• pp.304-311
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• 2022

Purpose: The purpose of this study was to investigate the knowledge, awareness and performance of COVID-19 infection control among physical therapists and to identify the impact factors on performance Methods: Data were collected from March 16th to March 24th in 2022 from the physical therapist's in Busan. Data analysis was conducted on 170 surveys, after excluding 27 surveys that were found to be unsuitable for data analysis. Results: When correlating the study variables, knowledge and awareness were found to have a positive, meaningful correlation with performance. Performance of COVID-19 personal infection control regression analysis showed that the working department (clinic and long-term care hospital), clinical experience, the more knowledgeable, the awareness (personal), and the more clinical experience had significant positive impacts on the performance of COVID-19 infection control. Performance of COVID-19 treatment room infection control regression analysis showed that the working department (long-term care hospital), educational experience, the awareness (treatment room) had significant positive impacts on the performance of COVID-19 infection control Conclusion: The results of this study may be used as basic data for educating physical therapist's working at the COVID-19 response department. This study suggests that physical therapist's need educational programs to improve their knowledge and awareness and performance of infection control against infectious diseases such as COVID-19. Differentiated physical therapists practice education curricula must be developed and provided after understanding the varying characteristic of physical therapist's with different levels of work experience.

• 대한의생명과학회지
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• 제29권4호
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• pp.344-354
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• 2023

This study emphasizes the importance of early diagnosis and response to COVID-19, leading to the development of a rapid diagnostic kit using quantum dots. The research focuses on finely tuning bioconjugation with quantum dots to enhance the accuracy and sensitivity of COVID-19 diagnosis. We have developed a COVID-19 rapid diagnostic kit that exhibits a sensitivity more than 50 times higher than existing COVID-19 diagnostic kits. Quantum dots enable the accurate detection of COVID-19 viral antigens even at low concentrations, providing a rapid response in the early stages of infection. The COVID-19 quantum dot diagnostic kit offers quick analysis time, utilizing the quantum properties of particles to swiftly measure COVID-19 infection for immediate response and isolation measures. Additionally, this diagnostic kit allows for multiple analyses with ease, as multiple quantum dots can detect various antigens and antibodies simultaneously in a single experiment. This efficiency enhances testing, reduces sample requirements, and lowers experimental costs. The application of this diagnostic technology is anticipated in the future for early diagnosis and monitoring of other infectious diseases.

• Child Health Nursing Research
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• 제30권2호
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• pp.154-163
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• 2024

Purpose: This study is descriptive research aiming to identify factors influencing the stigma experienced by college students with coronavirus disease 2019 (COVID-19), focusing on COVID-19 pandemic stress, depression, and fear of negative evaluation as the main variables. Methods: An online survey was administered to 175 college students who had been diagnosed with COVID-19 from January to May 2022 and were enrolled in universities in Seoul, Cheongju, and Daegu, South Korea. The survey collected data on pandemic stress, depression, fear of negative evaluation, and stigma. The data were analyzed using the t-test, ANOVA, the Scheffe test, Pearson's correlation coefficients, and stepwise multiple regression in SPSS/WIN 26.0. Results: We analyzed differences in stigma scores based on general characteristics of the college students and found significant differences in stigma scores by age, major satisfaction, interpersonal satisfaction, date of COVID-19 confirmation, treatment modality, and recent subjective health condition. Factors influencing stigmatization were identified as COVID-19 pandemic stress, depression, date of COVID-19 confirmation, treatment modality, recent subjective health condition, and major satisfaction, with an overall explanatory power of 37.6%. Conclusion: This study is significant as it identifies emotional changes across various aspects of pandemic stress, depression, fear of negative evaluation, and stigma among college students who have been diagnosed with COVID-19. The findings of this study suggest the development of programs to reduce psychological distress and enhance mental health management skills among these students.

• International Journal of Internet, Broadcasting and Communication
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• 제16권2호
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• pp.43-49
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• 2024

In early 2020, as the COVID-19 pandemic hit the world, widespread changes occurred throughout society. COVID-19 also brought changes in consumers' consumption behaviors and preferences. This study aims to find out how the current status of the tourism industry and the coffee industry has changed since the end of COVID-19 by conducting big data analysis focusing on the search frequency of Naver, Google, and the following, which are representative social networks in Korea. Designating "Coffee Industry + Tourism Industry" as the representative keyword, January 1, 2020 to December 31, 2020, the time of each COVID-19 outbreak, was set before the COVID-19 type, and January 1, 2023 to December 31, 2023 was set after the end of COVID-19. Based on the analyzed search binder big data analysis within the period, we would like to find out how the current status of the tourism industry and the coffee industry has changed since the end of COVID-19. Finaly, the coffee and tourism industries are on the path of recovery and growth. In particular, the rise in coffee consumption, the recovery of the number of tourists, the emphasis on local tourism, and the strengthening of links with global markets are prominent.

• Korean Journal of Radiology
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• 제21권8호
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• pp.1018-1023
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• 2020

The coronavirus disease (COVID-19) outbreak has reached global pandemic status as announced by the World Health Organization, which currently recommends reverse transcription polymerase chain reaction (RT-PCR) as the standard diagnostic tool. However, although the RT-PCR test results may be found negative, there are cases that are found positive for COVID-19 pneumonia on computed tomography (CT) scan. CT is also useful in assessing the severity of COVID-19 pneumonia. When clinicians desire a CT scan of a patient with COVID-19 to monitor treatment response, a safe method for patient transport is necessary. To address the engagement of medical resources necessary to transport a patient with COVID-19, our institution has implemented the use of mobile CT. Therefore, we report two cases of COVID-19 pneumonia evaluated by using mobile cone-beam CT. Although mobile cone-beam CT had some limitations regarding its image quality such as scatter noise, motion and streak artifacts, and limited field of view compared with conventional multi-detector CT, both cases had acceptable image quality to establish the diagnosis of COVID-19 pneumonia. We report the usefulness of mobile cone-beam CT in patients with COVID-19 pneumonia.