• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.31 no.5
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• pp.417-421
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• 2005

This study was to analyze the changes of levels of alkaline phosphatase before and after enucleation of jaw cysts combined with bone grafting, and to evaluate biochemically the effectiveness of the early detection of bone healing and infection as a prognostic marker. Eighteen patients (13 males, 5 females) with cystic lesions of the jaws were divided into two groups. The bone graft group underwent enucleation and bone graft. The control group underwent only enucleation. Both groups were measured levels of ALP before surgery, and plus-minus 4 weeks postoperatively. The more discriminating results were obtained in the bone graft group. The results were as follows : 1. Levels of ALP after enucleation of jaw cysts were decreased in all patients with and without bone graft. 2. The bone graft group showed more marked decrease in variation of levels of ALP than the control group.(p=0.008) This should be considered as a result of increased osteoblastic activity and new bone formation. 3. Such variation could be used as a prognostic marker for bone healing after cyst operation. In the cost/benefit ratio, measurement of ALP activity could be useful as a convenient procedure in routine clinical practice.

• The KIPS Transactions:PartD
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• v.14D no.1 s.111
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• pp.107-120
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• 2007

When it tomes to IT investment, it's a challenge for the management to make the right decision. Unlike investment in other business area, it's hard to measure direct cost vs. effect in IT business. To validate the investment in IT, it is required to establish objective assessment system that both provider and beneficiary of information can accept, and it is also required to suggest an assessment tool of fixed quantity that includes measuring standards and method for the economic effect of new investment. This study, therefore, has developed IT ROI Methodology that can prove investment validity by accepting the strong points of the existing models while complementing their weak points and by analyzing IT Investment and IT Efforts. It also has built an IT ROI System that reflects the methodology which is applied to 21 companies of 5 business categories. This system is designed to provide effective and objective decision-making tool for IT investment by proving what positive impacts IT could have on business activities.

• Journal of the Korean Society of Safety
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• v.14 no.2
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• pp.62-69
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• 1999

The quantitative risk assessment and consequence analysis by accident scenario in the process of EPS(Expendable Poly Stylene) reaction process are conducted. And the decision making process is studied followed by selecting various alternatives to safety management and facility improvement. The result are as follows; 1) The object of decision making through comprehensive risk assessment are the scenario which can cause four major accident, which are made by process analysis, work analysis and hazard identification. 2) Frequency analysis of ETA, FTA, HRA and consequence analysis of accident to each have been conducted. The each frequency values are yielded $9.2{\times}10_{-5}/yr$ to scenarios $1, 8.2{\times}10^{-4}/yr$ to scenario 2, $4.5{\times}10^{-6}/yr$ scenario 3 and $1.8{\times}10^{-7}/yr$ to scenario 4. The each scenarios have been conducted consequence analysis. 3) The calculated values have been obtained 4.00 to scenario 1, 3.25 to scenario 2, 2.43 to scenario 3 and 1.34 to scenario 4, as the weight value had been applied to the quantitative and normalized criteria of all components. As a risk criteria, scenario 1 have been selected, which is the most dangerous scenario as a result of ranking the scenario. 4) According to the importance of FTA and contribute to scenario 1, the cost-benefit values are yielded $8.05\times10^5[￦/yr]$ to final alternative(Al), $1.55{\times}10^5[￦/yr]$ to final alternative(A2) and $2.32{\times}10^5[￦/yr]$ to final alternative(A3). As a result of final alternative(Al) has been selected, which is the most optimized alternative.

• Journal of Korean society of Dental Hygiene
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• v.12 no.5
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• pp.999-1006
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• 2012

Objectives : The purpose of this study was to understand and compare the knowledge of the adolescents and adults among the residents of Seoul metropolitan city about water fluoridation program. Methods : A total of 613 adolescents and adults between the age of 15 and 31-49 was surveyed by the questionnaire. Among them, the source of drinking water, the source of cooking water, awareness of caries prevention effect of water fluoridation program, awareness of cost benefit of health insurance of water fluoridation program, approval of water fluoridation program, awareness of health safety of water fluoridation program were surveyed. Results : 85.5% of adolescents and 88.9% of adults were surveyed to use public water supply for drinking water, and 95.3% of adolescents and 96.8% of adults were surveyed to use public water supply for cooking water. But only 14.0% of adolescents, comparing to the 42.1% of adults, were surveyed to be aware of the caries prevention effect of water fluoridation, and only 6.0% of adolescents, comparing to the 24.6% of adults, were surveyed to be aware of the caries prevention effect of water fluoridation to reduce to health insurance expenditure. About 82.6% of adolescents, comparing to the 92.1% of adults, were surveyed to vote for the fluoridation program, and only 6.8% of adolescents, comparing to the 28.6% of adults, were surveyed to be aware of health safety of water fluoridation program. Conclusions : Extensive oral health education program to the adolescents are necessary about using water fluoridation to prevent the dental caries.

• Journal of the Korean Society for Marine Environment & Energy
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• v.16 no.3
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• pp.217-225
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• 2013

It is time to develop new renewable energy that could fundamentally replace fossil fuel, which has been increasingly needed due to environmental pollution and energy security. Korean marine bio-energy development project is planned to produce 50% of total bioenergy. This study attempts to measure the greenhouse gas emission reduction benefits of marine bio-energy development project through contingent valuation method. Single bounded dichotomous choice (SBDC) is applied with spike model. The results show that the average willingness to pay are estimated to be KRW 4,190 at SBDC, per household per year. If the result has been expanded to the region which is survey conducted, KRW 50.1 billion annually. These quantitative information can be usefully utilized in the cost benefit analysis to implement project and policy-making for the industrialization of marine bio-energy development project.

• Journal of Labour Economics
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• v.25 no.1
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• pp.131-160
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• 2002

This article tried to find out the individual wage effect of training. This Article used 1998, 1999 KLIPS(Korea Labor and Income Panel Study) panel data. The size of the individual wage effect of training was twice of tenure's, and had significance. Training had a good effect on the job satisfaction and carrier development. To overcome self selection bias, this article regressed the first difference of wage equations, but we didn't get the significant results. Dividing sample into quitters and non-quitters in order to investigate the relation between training cost and benefit, we regressed separately the each first difference of wage equation. On quitters, the individual effect of training appeared significantly, but on non-quitters, it didn't. This results mean that employer does not raise wage rate according to upgraded skill originated in incumbent's training. And the results also mean that the upgraded skill of employee who quit pre-employer is recognized by new employer, and his wage rate rises in his new job.

• Asian-Australasian Journal of Animal Sciences
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• v.28 no.11
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• pp.1599-1605
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• 2015

Twenty Holstein calves were used to investigate the effects of mannanoligosaccharides (MOS) supplementation in the whole milk on growth performance, faecal score, faecal pH, selected faecal bacterial populations and health during the preweaning period. Healthy calves selected by clinical examination were allocated to one of the two groups (control [CG] and experimental [EG]) at 5 days old. Each group consisted of 5 male and 5 female calves. Each calf in EG was supplemented with 7 g/d of a MOS product (Celmanax) from 5 days to 56 days of age. MOS supplement was mixed with the whole milk once in the morning and administered to the calves in EG via nipple bottle, whereas the calves in CG were fed the whole milk without MOS. Calves were weaned at 56 days of age. The final body weight, average daily weight gain (ADG) and average daily feed intake (ADFI) were statistically similar (p>0.05) but were higher by 3.70%, 6.66%, and 10.97%, respectively, in MOS than in control calves. Feed efficiency (ADG/ADFI) was also similar in two calves group. While faecal scores did not differ on day 5, 7, 14, 21, 28, 42, 49, and 56 between groups, EG had a higher faecal score (p = 0.05) than CG on day 35. Faecal concentration of Lactobacillus was lower (p<0.05) in EG compared with CG. No differences (p>0.05) in faecal concentrations of Bifidobacterium, Clostridium perfringens, and Escherichia coli were found between groups. Although there were no significant differences (p>0.05) in the incidence of diarrhoea, treatment days for diarrhoea and the costs associated with diarrhoea treatments between groups, collectively, the observed reductions in treatment days and the cost of diarrhoea treatments accompanying increases in final body weight, ADG and ADFI for EG may indicate potential benefit of MOS in treatment of diarrhoea.

• Journal of Microbiology and Biotechnology
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• v.23 no.5
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• pp.587-601
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• 2013

During the last few decades, it has become evident that the compatibility of the yeast biochemical environment with the ability to process and translate the RNA transcript, along with its capacity to modify a translated protein, are relevant requirements for selecting this host cell for protein expression in several pharmaceutical and clinical applications. In particular, Pichia pastoris is used as an industrial host for recombinant protein and metabolite production, showing a powerful capacity to meet required biomolecular target production levels in high-throughput assays for functional genomics and drug screening. In addition, there is a great advantage to using P. pastoris for protein secretion, even at high molecular weights, since the recovery and purification steps are simplified owing to relatively low levels of endogenous proteins in the extracellular medium. Clearly, no single microexpression system can provide all of the desired properties for human protein production. Moreover, chemical and physical bioprocess parameters, including culture medium formulation, temperature, pH, agitation, aeration rates, induction, and feeding strategies, can highly influence product yield and quality. In order to benefit from the currently available wide range of biosynthesis strategies using P. pastoris, this mini review focuses on the developments and technological fermentation achievements, providing both a comparative and an overall integration analysis. The main aim is to highlight the relevance and versatility of the P. pastoris biosystem to the design of more cost-effective microfactories to meet the increasing demands for recombinant membrane proteins and clinical antibodies for several therapeutic applications.

• Journal of Korean Society of Environmental Engineers
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• v.31 no.6
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• pp.428-433
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• 2009

Dissolved oxygen is considered as one of the important water-quality constituents in streams from one century ago and fishes perish in low dissolved oxygen concentration. Environmental scientists and engineers have introduced the deterministic model to estimate dissolved oxygen concentration of streams and recommended the use of the Delta Method (DM), Approximate Delta Method (ADM), Extreme Value Method (EVM) and Optimization Method (OPT) which can be applied in no spatial variation of dissolved oxygen. The diurnal or annual variation of dissolved oxygen is mainly determined from the parameters such as reaeration rate, 1st production rate and respiration rate which are related to dissolved oxygen. Each method was briefly introduced and applied to two sampling sites of Anseong Stream watershed in this paper. The limitation, advantages and disadvantages of each method were reviewed and analyzed after running the each method. From these analyses, the benefit-cost approach to estimate dissolved oxygen effectively in streams was recommended.

• Journal of The Korean Society of Agricultural Engineers
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• v.51 no.6
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• pp.45-52
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• 2009

This study was conducted in the process that the basic plan of the formation of the thermal energy complex in the Iwon reclaimed land of Taean was being made. Targeting for the large-sized greenhouse to be made in this area, it examined the cooling and heating load and the amount of ventilation, and also analyzed the economic efficiency of heating. The research results are as per the below: The minimum ambient temperature of this area was measured on January 7, 2001, which was $-18.7^{\circ}C$, and the maximum ambient temperature of this area was measured on July 24, 1994, which was $36.7^{\circ}C$. The maximum heating load was 39,011 MJ/h, but the date when the maximum heating load was not consistent with the date when the minimum temperature was measured. The maximum cooling load was 88,562MJ/h, It was approximately 2.3 times of the maximum heating load, which was measured at 14:00 hours on September 4, 2000. The maximum amount of ventilation heat was 138,639MJ/h. Assuming the rate of solar heat use as 10%, 20%, 50%, and 100%, the total sum of cost-benefit would be ￦-193,450,000, ￦-634,930,000, ￦-3,372,960,000, and ￦-9,850,420,000, respectively 20 years later. The break-even point of the geothermal heat pump would be about 4 years for 10% use, about 3 years for 20% or 50% use, and approximately 6 years for 100% use. It was found that 50% use would be most advantageous. In case two systems are combined, the break-even point will be 10 years, 8 years, and 11 years respectively.