• Title/Summary/Keyword: corpora

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Comparison of Non-surgical and Surgical Recovery of Fertilized Eggs in Superovulated Rabbits (과배란 처리 가토에서 수정란의 비외과적 회수와 외과적 회수의 비교)

  • 심금섭;변태호;이재근
    • Korean Journal of Animal Reproduction
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    • v.8 no.1
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    • pp.16-21
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    • 1984
  • This experiment was carried out to compare with the nonsurgical and surgical recovery of fertilized eggs in super-ovulated rabbits. Sixty-four eggs recovered were transferred to twelve synchronized, pseudopregnant rabbits to test the viability of the eggs by surgical transfer. Each group(I, II, III) received a single subcutaneous injection of 5mg PGF2${\alpha}$/kg B.W. at 24(Group I), 48(Group II) and 72 hours (Group III) after mating, respectivity. After the administration of PGF2${\alpha}$, vaginal washings were conducted at 3, 6, 9, 12 and 24 hrs, and frequency of vaginal washing was 5 times for the each group (I, II, III). In Group (IV, V, Ⅵ), the rabbits were killed to recover the fertilized eggs from the genital tract at 24(Group Ⅵ), 48(Group V) and 72 hours (Group Ⅵ) after mating, respectively. The results obtained were as follows: 1. Of the total eggs, 69.3%, 73.4% and 66.9% were recovered for Group I, II and III, respectively from the vagina within 6 hrs after PGF2${\alpha}$ injection and particularly for Group III. 2. The rates of egg recovery versus the number of corpora lutea were 55 (51.6-60%), 35.8 (24-52.6%), 33.4 (25-47%) and 72 (70.7-73.0)%, 60.3 (50-71.4)%, 449(44.4-45.5)% in Group I, II, III and Group IV, V, Ⅵ, respectively. 3. Most of eggs recovered were one-cell stage in Group Iand Group IV. More than one half of the eggs recovered in Group II and V were over eight-cell stage, and most of the eggs were so in Group III and Ⅵ. 4. When sixty-four eggs recovered between 24 to 72 hours after mating were transferred to pseudopregnant rabbits. Three recipients were pregnant, and the rate of pregnancy was 25%.

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Studies on Phenotype of Reproduction and Production of Human Growth Hormone(hGH) with Transgenic Rats II. Different Reproductive Phenotypes Determined by hGH Levels in hGH Transgenic Rats (Human 성장호르몬을 도입한 Transgenic Rats의 작출과 번식표현형에 관한 연구 II. 형질전환된 Rats의 hGH수준이 번식표현형에 미치는 영향)

  • 장규태;김성현;성환후;주학진;박미령;윤창현
    • Korean Journal of Animal Reproduction
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    • v.22 no.2
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    • pp.137-143
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    • 1998
  • The effects of continuous GH(hGH) secretion on the female reproduction was studies in adults female transgenic rats expressing the hGH gene with a mouse whey acid protein (mWAP) promotor. Two line of transgenic female rats carrying the mWAP/hGH gene were established and used in the study. One was characterized by relatively high levels of serum hGH (high line), and the other had relatively low levels (low line). 1. High line female rats had recurring, Pseudopregancy-like estrous cycles accompanied by increased serum progesterone level for 2 weeks after ovulation, and they were fertile. 2. In the rats, luteinization occurred spontaneously without cervical stimulation, probably due to high levels of serum hGH, which has prolactin (PRL)-like activity in the rat. 3. Low line female rats had recurring, regular 4-days estrous PRL surge following cervical stimulation were not, detected and PRL secretion was not induced by a dopamine antagonist. 4. The ovarian tissue in this line had a much higher number of corpora lutea and grew much heavier than in normal littermates, suggesting impairment of PRL induced structural luteolized. Su, pp.ession of PRL secretion in the low line rats was, at least in part, due to a marked decrease in the number of lactotrophs in the pituitary. The present study shows that the serum hGH level plays a crucial role in regulating luteal function in female transgenic rats expressing the hGH gene.

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Chunking Korean and an Application (한국어 낱말 묶기와 그 응용)

  • Un Koaunghi;Hong Jungha;You Seok-Hoon;Lee Kiyong;Choe Jae-Woong
    • Language and Information
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    • v.9 no.2
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    • pp.49-68
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    • 2005
  • Application of chunking to English and some other European languages has shown that it is a viable parsing mechanism for natural languages. Although a small number of attempts have been made to apply chunking to the analysis of the Korean language, it still is not clear enough what criteria there are to identify appropriate units of chunking, and how efficient and valid the chunking algorithms would be when applied to some authentic Korean texts. The purpose of this research is to provide an alternative set of algorithms for chunking Korean, and to implement them, and to test them against some English-Korean parallel corpora, which is English and Korean bibles matched sentence by sentence. It is shown in the paper that aligning related texts and identifying matched phrases between the two languages can be achieved through appropriate chunking and matching algorithms defined on the morphologically-tagged parallel corpus. Chunking and matching processes are based on the content words rather than the function words, and the matching itself is done in terms of the transfer dictionary. The implementation is done in C and XML, and can be accessed through the Internet.

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Determination of Thematic Roles according to Syntactic Relations Using Rules and Statistical Models in Korean Language Processing (한국어 전산처리에서 규칙과 확률을 이용한 구문관계에 따른 의미역 결정)

  • 강신재;박정혜
    • Journal of Korea Society of Industrial Information Systems
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    • v.8 no.1
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    • pp.33-42
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    • 2003
  • This paper presents an efficient determination method of thematic roles from syntactic relations using rules and statistical model in Korean language processing. This process is one of the main core of semantic analysis and an important issue to be solved in natural language processing. It is problematic to describe rules for determining thematic roles by only using general linguistic knowledge and experience, since the final result may be different according to the subjective views of researchers, and it is impossible to construct rules to cover all cases. However, our hybrid method is objective and efficient by considering large corpora, which contain practical usages of Korean language, and case frames in the Sejong Electronic Lexicon of Korean, which is being developed by dozens of Korean linguistic researchers. To determine thematic roles more correctly, our system uses syntactic relations, semantic classes, morpheme information, position of double subject. Especially by using semantic classes, we can increase the applicability of our system.

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Effects of Shingihwanhapchangbudodam-Tang on the Estradiol Valerate-induced Polycystic Ovary in Rats (심기환합창부도담탕(腎氣丸合蒼附導痰湯)이 Estradiol Valerate로 유도된 흰쥐의 다낭성 난소에 미치는 영향)

  • Seo, Il-Bock;Kim, Hyung-Jun;Lee, Dong-Nyung;Yoo, Yung-Ki
    • The Journal of Korean Obstetrics and Gynecology
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    • v.20 no.1
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    • pp.84-98
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    • 2007
  • Purpose : Polycystic ovarian syndrome(PCOS) is a endocrine disorder and still remains as one of the common causes of anovulation in women of reproductive age. There are some evidences that nerve growth factor(NGF) is involved in the pathogenesis of PCOS. In this research, the effects of ShingihwanhapChangbudodam- Tang(SCT) on the estradiol valerate(EV)-induced polycystic ovary(PCO) were investigated in rats. Methods : PCO was induced by single intramuscular injection with EV(4mg) in female rats. Rats in PCO control group(n = 8) were EV injected and orally administrated distilled water for sixty days. Rats in SCT-treated group(n = 8) were EV injected and orally administrated SCT for same duration. The weights of body, ovary and adrenal gland were measured. And also, ovarian histopathology and NGF immunohistochemistry were performed. Results : The weights of ovaries in SCT-treated group were significantly increased compared with control group. The numbers of secondly and mature follicles, and corpora lutea in SCT-treated group were significantly increased compared with control group. The numbers of atretic follicles were significantly decreased compared with control group. The expression of NGF positive reaction in the ovarian granulosa cells of SCT-treated group were lesser observed than control group. Conclusion : From the these results, we concluded that ShingihwanhapChangbudodam-Tang(SCT) has inhibitory effect on the development of EV-induced polycystic ovary. And it's effect may be related with decreased NGF activities in the ovary.

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Evaluation of the Discordance between Sentence Polarities and Keyword Polarities by Using MUSE Sentiment-Annotated Corpora (MUSE 감성주석코퍼스를 활용한 문장 극성과 키워드 극성간의 불일치 현상에 대한 분석)

  • Cho, Donghee;Shin, Donghyok;Joo, Heejin;Chae, Byoungyeol;Cao, Wenkai;Nam, Jeesun
    • Annual Conference on Human and Language Technology
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    • 2016.10a
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    • pp.195-200
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    • 2016
  • 본 연구는 MUSE 감성 코퍼스를 활용하여 문장의 극성과 키워드의 극성이 얼마만큼 일치하고 일치하지 않은지를 분석함으로써 특히 문장의 극성과 키워드의 극성이 불일치하는 유형에 대한 연구의 필요성을 역설하고자 한다. 본 연구를 위하여 DICORA에서 구축한 MUSE 감성주석코퍼스 가운데 IT 리뷰글 도메인으로부터 긍정 1,257문장, 부정 1,935문장을, 맛집 리뷰글 도메인으로부터는 긍정 2,418문장, 부정 432문장을 추출하였다. UNITEX를 이용하여 LGG를 구축한 후 이를 위의 코퍼스에 적용하여 나타난 양상을 살펴 본 결과, 긍 부정 문장에서 반대 극성의 키워드가 실현된 경우는 두 도메인에서 약 4~16%의 비율로 나타났으며, 단일 키워드가 아닌 구나 문장 차원으로 극성이 표현된 경우는 두 도메인에서 약 25~40%의 비교적 높은 비율로 나타났음을 확인하였다. 이를 통해 키워드의 극성에 의존하기 보다는 문장과 키워드의 극성이 일치하지 않는 경우들, 가령 문장 전체의 극성을 전환시키는 극성전환장치(PSD)가 실현된 유형이나 문장 내 극성 어휘가 존재하지 않지만 구 또는 문장 차원의 극성이 표현되는 유형들에 대한 유의미한 연구가 수행되어야 비로소 신뢰할만한 오피니언 자동 분류 시스템의 구현이 가능하다는 것을 알 수 있다.

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Expression of peroxiredoxin I regulated by gonadotropins in the rat ovary

  • Lee, Yu-Il;Kang, Woo-Dae;Kim, Mi-Young;Cho, Moon-Kyoung;Chun, Sang-Young
    • Clinical and Experimental Reproductive Medicine
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    • v.38 no.1
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    • pp.18-23
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    • 2011
  • Objective: Peroxiredoxins (Prxs) play an important role in regulating cellular differentiation and proliferation in several types of mammalian cells. This report examined the expression of Prx isotype I in the rat ovary after hormone treatment. Methods: Immature rats were injected with 10 IU of pregnant mare's serum gonadotropin (PMSG) to induce the growth of multiple preovulatory follicles and 10 IU of human chorionic gonadotropin (hCG) to induce ovulation. Immature rats were also treated with diethylstilbestrol (DES), an estrogen analogue, to induce the growth of multiple immature follicles. Northern blot analysis was performed to detect gene expression. Cell-type specific localization of Prx I mRNA were detected by in situ hybridization analysis. Results: During follicle development, ovarian Prx I gene expression was detected in 3-day-old rats and had increased in 21-day-old rats. The levels of Prx I mRNA slightly declined one to two days following treatment with DES. A gradual increase in Prx I gene expression was observed in ovaries obtained from PMSG-treated immature rats. Furthermore, hCG treatment of PMSG-primed rats resulted in a gradual stimulation of Prx I mRNA levels by 24 hours (2.1-fold increase) following treatment, which remained high until 72 hours following treatment. In situ hybridization analysis revealed the expression of the Prx I gene in the granulosa cells of PMSG-primed ovaries and in the corpora lutea of ovaries stimulated with hCG for 72 hours. Conclusion: These results demonstrate the gonadotropin and granulosa cell-specific stimulation of Prx I gene expression, suggesting its role as a local regulator of follicle development.

Therapeutic Effect of Korean Red Ginseng Extract on Infertility Caused by Polycystic Ovaries

  • Jung, Ji-Hun;Park, Hyun-Tae;Kim, Tak;Jeong, Moon-Jin;Lim, Sung-Chul;Nah, Seung-Yeol;Cho, Ik-Hyun;Park, Soo-Hyun;Kang, Seong-Soo;Moon, Chang-Jong;Kim, Jong-Choon;Kim, Sung-Ho;Bae, Chun-Sik
    • Journal of Ginseng Research
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    • v.35 no.2
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    • pp.250-255
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    • 2011
  • Polycystic ovarian syndrome (PCOS) is a very common endocrine disorder in women of reproductive age. Nerve growth factor (NGF) may be involved in the pathogenesis of PCOS. In this study, we investigated the effect of Korean red ginseng extract (KRGE) on the ovarian morphology and NGF expression in an estradiol valerate (EV)-induced rat model. Polycystic ovaries were induced by a single intramuscular injection of estadiol valerate (4 mg, dissolved in sesame oil) in adult cycling rats. KRGE was administered orally (200 mg/kg body weight/day) for 60 consecutive days, beginning 60 days after the induction. Ovarian morphology was almost normalized and NGF was normalized in the EV+KRGE group. KRGE lowered the high numbers of antral follicles and increased the number of corpora lutea in the polycystic ovaries. The results are consistent with a beneficial effect of KRGE in the treatment of PCOS.

Combinatory Categorial Grammar for the Syntactic, Semantic, and Discourse Analyses of Coordinate Constructions in Korean (한국어 병렬문의 통사, 의미, 문맥 분석을 위한 결합범주문법)

  • Cho, Hyung-Joon;Park, Jong-Cheol
    • Journal of KIISE:Software and Applications
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    • v.27 no.4
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    • pp.448-462
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    • 2000
  • Coordinate constructions in natural language pose a number of difficulties to natural language processing units, due to the increased complexity of syntactic analysis, the syntactic ambiguity of the involved lexical items, and the apparent deletion of predicates in various places. In this paper, we address the syntactic characteristics of the coordinate constructions in Korean from the viewpoint of constructing a competence grammar, and present a version of combinatory categorial grammar for the analysis of coordinate constructions in Korean. We also show how to utilize a unified lexicon in the proposed grammar formalism in deriving the sentential semantics and associated information structures as well, in order to capture the discourse functions of coordinate constructions in Korean. The presented analysis conforms to the common wisdom that coordinate constructions are utilized in language not simply to reduce multiple sentences to a single sentence, but also to convey the information of contrast. Finally, we provide an analysis of sample corpora for the frequency of coordinate constructions in Korean and discuss some problematic cases.

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Studies on In Vivo Embryo Production by FSH-P and SUPER-OV in Korean Native Cattle I. The Factors Influencing In Vivo Embryo Production by Condition of Superovulation Treatment (한우에서 FSH-P와 SUPER-OV에 의한 체내 수정란 생산에 관한 연구 I. 다배란 처리 조건에 따른 체내 수정란 생산에 영향을 미치는 요인)

  • 김흥률;김덕임;원유석;김창근;정영채;서길웅
    • Journal of Embryo Transfer
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    • v.12 no.1
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    • pp.37-48
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    • 1997
  • I. The Factors Influencing In Vivo Embryo Production by Condition of Superovulation Treatment These studies were carried out to establish an effective and practical system for comrnercialization of embryo production techniques by analyzing several factors influencing in vivo embryo production on superovulation treatment in Korean native cattle. In vivo embryos were flushed 226 times from 128 donors.The results obtained from the studies on the factors influencing in vivo embryo production by superovulation treatment were as follows : FSH-P had a significiant advantage(83.0%) over SUPER-OV in the percentage of fertilized embryos(P<0.01). No difference was found loetween FSH-P and SUPER-OV in the percentage of transferable and freezable embryos.2. The response of superovulation by SUPER-OV was greater than that of FSH-P The donors having 8~9 and more than 10 of corpora lutea(CL) derived by FSH-P were 40.0%(most frequent) and 33%, respectively. The donors having more than 12 and 10 CL derived by SUPER -OV were 33.3% (most frequent) and 56.6%, respectively.3. Embryo production after treatment of repeated superovulation was remarkablely decreased at 3rd time by FSH-P but did not differ among 1, 2 and 3rd times by SUPER-OV. Embryo production on intervals of repeated superovulation was significantly different for the number and percentage of fertilized, transferable and free-zable' embryos in FSH-P (P<0.01) and rernarkablely decreased in repeated superovulation of 81~120 interval days. The SUPER-OV showed no differences in interval days of repeated superovulation and was found better than FSH-P in the response of repeated superovulation. (Key words : in Vivo embryo, superovulation, FSH -P, SUPER-OV)

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