• Journal of Oral Medicine and Pain
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• v.40 no.3
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• pp.115-123
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• 2015

Purpose: The aim of this study was to elucidate the coordination patterns of the sternocleidomastoid and posterior cervical muscles in response to symmetrical and asymmetrical jaw functions in normal adults. Methods: Twenty-seven healthy volunteers (8 females, 19 males; mean age, $30.4{\pm}2.5$ years) participated in this study. Surface electromyography (EMG) was used to record activities in the masseter, suprahyoid, sternocleidomastoid, and posterior cervical muscles at rest and during maximum tooth clenching, biting of a cotton roll with the anterior teeth, unilateral biting of a cotton roll with the posterior teeth, bilateral biting of cotton rolls with the posterior teeth, and jaw opening while seated. Normalized amplitude, activity indices, and asymmetry indices were compared between the muscles and the jaw tasks. Results: During symmetrical jaw functions (e.g., tooth clenching, biting with the anterior teeth, bilateral biting with the posterior teeth, jaw opening), the sternocleidomastoid and posterior cervical muscles showed elevated EMG amplitudes compared with the resting condition. The co-activation pattern of the sternocleidomastoid muscle was more pronounced than those of the posterior cervical muscles during these tasks. During asymmetrical jaw functions (e.g., unilateral biting with the posterior teeth), the ipsilateral sternocleidomastoid and masseter muscles showed higher contraction activity than did the contralateral muscles, but the contralateral posterior cervical muscles were more active than the ipsilateral muscles. Conclusions: The sternocleidomastoid and posterior cervical muscles were shown to be co-activated and coordinated anteroposteriorly or bilaterally according to symmetrical or asymmetrical jaw function. These results suggest an integrated neural control mechanism for the jaw and neck muscles, and provide further evidence supporting the intimate functional coupling between the trigeminal and cervical neuromuscular systems.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.4087-4091
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• 2012

To evaluate the relationship between polymorphisms (28 bp repeated sequences in 5'-UTR and 6-bp ins/del in 3'-UTR) in then thymidylate synthetase gene (TS) and risk of colorectal, colon and rectal cancers, we conducted a case-control study with 315 cases of colorectal cancer and 439 population-based controls in Jiangsu province, China. TS genotypes were identified using PCR.RFLP (restriction fragment length polymorphism) methods. Odds ratios (ORs) were estimated with an unconditional logistic regression model. We found that the distributions of 5'-UTR genotypes in TS were significantly different between controls and male colon cases (${\chi}^2$=8.25, P = 0.016). Compared with 3R/3R genotype, individuals with the 2R allele were at an increased risk of colon cancer (age-, BMI-, smoking- and alcohol drinking-adjusted OR=1.98, 95%CI: 1.11-3.53) among men. In ccontrast, the 6-bp ins/del polymorphism at the TS 3'- UTR did not influence risk of the colorectal, colon and rectal cancers. When combined genotypes for both TS 5'-UTR and 3'-UTR polymorphisms were evaluated, individuals with the 5'-UTR 2R allele had a OR of 3.61 (95%CI: 1.38-9.49) for colon cancer among men with the 3'-UTR .6bp/-6bp genotype. These results show that the polymorphism of the 28 bp repeated sequences in TS 5'-UTR could influence susceptibility to colon cancer and that there was a coordinated effect between TS 3'-UTR and 5'-UTR polymorphisms in increasing risk of colon cancer among Chinese men.

• The Plant Pathology Journal
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• v.36 no.1
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• pp.54-66
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• 2020

This study was conducted to evaluate usefulness of numerical weather prediction data generated by the Unified Model (UM) for plant disease forecast. Using the UM06- and UM18-predicted weather data, which were released at 0600 and 1800 Universal Time Coordinated (UTC), respectively, by the Korea Meteorological Administration (KMA), disease forecast on bacterial grain rot (BGR) of rice was examined as compared with the model output based on the automated weather stations (AWS)-observed weather data. We analyzed performance of BGRcast based on the UM-predicted and the AWS-observed daily minimum temperature and average relative humidity in 2014 and 2015 from 29 locations representing major rice growing areas in Korea using regression analysis and two-way contingency table analysis. Temporal changes in weather conduciveness at two locations in 2014 were also analyzed with regard to daily weather conduciveness (C_i) and the 20-day and 7-day moving averages of C_i for the inoculum build-up phase (C_inc) prior to the panicle emergence of rice plants and the infection phase (C_inf) during the heading stage of rice plants, respectively. Based on C_inc and C_inf, we were able to obtain the same disease warnings at all locations regardless of the sources of weather data. In conclusion, the numerical weather prediction data from KMA could be reliable to apply as input data for plant disease forecast models. Weather prediction data would facilitate applications of weather-driven disease models for better disease management. Crop growers would have better options for disease control including both protective and curative measures when weather prediction data are used for disease warning.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.8
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• pp.2797-2820
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• 2015

In order to accommodate huge number of antennas in a limited antenna size, a large scale antenna array is expected to have a three dimensional (3D) array structure. By using the Active Antenna Systems (AAS), the weights of the antenna elements arranged vertically could be configured adaptively. Then, a degree of freedom (DOF) in the vertical plane is provided for system design. So the three-dimension MIMO (3D MIMO) could be realized to solve the actual implementation problem of the massive MIMO. However, in 3D massive MIMO systems, the pilot contamination problem studied in 2D massive MIMO systems and the inter-cell interference as well as inter-vertical sector interference in 3D MIMO systems with vertical sectorization exist simultaneously, when the number of antenna is not large enough. This paper investigates the interference management towards the above challenges in 3D massive MIMO systems. Here, vertical sectorization based on vertical beamforming is included in the concerned systems. Firstly, a cooperative joint vertical beams adjustment and pilot assignment scheme is developed to improve the channel estimation precision of the uplink with pilots being reused across the vertical sectors. Secondly, a downlink interference coordination scheme by jointly controlling weight vectors and power of vertical beams is proposed, where the estimated channel state information is used in the optimization modelling, and the performance loss induced by pilot contamination could be compensated in some degree. Simulation results show that the proposed joint optimization algorithm with controllable vertical beams' weight vectors outperforms the method combining downtilts adjustment and power allocation.

• Journal of Communications and Networks
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• v.14 no.6
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• pp.662-671
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• 2012

Plug-in hybrid electric vehicles (PHEVs) will be widely used in future transportation systems to reduce oil fuel consumption. Therefore, the electrical energy demand will be increased due to the charging of a large number of vehicles. Without intelligent control strategies, the charging process can easily overload the electricity grid at peak hours. In this paper, we consider a smart charging and discharging process for multiple PHEVs in a building's garage to optimize the energy consumption profile of the building. We formulate a centralized optimization problem in which the building controller or planner aims to minimize the square Euclidean distance between the instantaneous energy demand and the average demand of the building by controlling the charging and discharging schedules of PHEVs (or 'users'). The PHEVs' batteries will be charged during low-demand periods and discharged during high-demand periods in order to reduce the peak load of the building. In a decentralized system, we design an energy cost-sharing model and apply a non-cooperative approach to formulate an energy charging and discharging scheduling game, in which the players are the users, their strategies are the battery charging and discharging schedules, and the utility function of each user is defined as the negative total energy payment to the building. Based on the game theory setup, we also propose a distributed algorithm in which each PHEV independently selects its best strategy to maximize the utility function. The PHEVs update the building planner with their energy charging and discharging schedules. We also show that the PHEV owners will have an incentive to participate in the energy charging and discharging game. Simulation results verify that the proposed distributed algorithm will minimize the peak load and the total energy cost simultaneously.

• Journal of the Korean Applied Science and Technology
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• v.19 no.2
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• pp.103-107
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• 2002

Diphosphine dinuclear gold(I) complexes were synthesized from the reaction of bridged diphosphines and gold ions. As a bridged diphosphine, 1,2-bis(diphenylphosphino)metbane (dppm) or 1,1'-Bis(diphenylphosphino) ferrocene (dppf) was introduced. As anionic ligands, CI was first coordinated to Au, resulting in (diphosphine)$(AuCl)_{2}$. Then, the ligand, SPh, was substituted for Cl in the chloride complex to give (diphosphine)$(AuSPh)_{2}$. As a result, three digold complexes, (dppm)$(AuCl)_{2}$. (I), (dppf)$(AuCl)_{2}$. (II), and (dppf)$(AuSPh_{2}$. (III) were prepared in this study. The thermal properties were investigated at first hand to confirm that the gold complexes were in fact formed. The digold complexes were decomposed above $200^{\circ}C$ while the ligand, dppm or dppf, melts under $180^{\circ}C$ The photoluminescence (PL) spectra of the spin-coated thin films showed the maximum peak at 590, 595, and 540nm for the complex, I, II, and III, respectively. These complexes were found to give the orange color phosphorescence. Therefore, these digold complexes can be candidates for orange-red phosphorescent materials in organic electroluminescent devices (OELD). Further studies on application of the complexes as a dopant in an emitting layer are in progress in our laboratory.

• Journal of the Earthquake Engineering Society of Korea
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• v.25 no.3
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• pp.103-110
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• 2021

A shake table test is conducted for the three-story reinforced concrete building structure using 0.28 g, 0.5 g, 0.75 g, and 1.0 g of seismic input motions based on the Gyeongju earthquake. Computational efforts are made in parallel to explore the mechanical details in the structure. For engineering practice, the elastic modulus of concrete and rebar in the dynamic analysis is reduced to 38% and 50%, respectively, to calibrate the structure's natural frequencies. The engineering approach to the reduced modulus of elasticity is believed to be due to the inability to specify the flexibility of the actual boundary conditions. This aspect may lead to disadvantages of nonlinear dynamic analysis that can distort local stress and strain relationships. The initial elastic modulus can be applied directly without the so-called engineering adjustment with infinite element models with spring and spring-dashpot boundary conditions. This has the advantage of imposing the system flexibility of the structure on the sub-boundary conditions of springs and damping devices to control its sensitivity in a serial arrangement. This can reflect the flexibility of realistic boundary conditions and the effects of system damping (such as the gap between a concrete footing and shake table, loosening of steel anchors, etc.) in scalar quantities. However, these spring and dashpot coefficients can only be coordinated based on experimental results, making it challenging to select the coefficients in-prior to perform an experimental test.

• Journal of Advanced Navigation Technology
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• v.23 no.2
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• pp.194-199
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• 2019

Natural disasters destroy decades of human effort and investments, thereby placing new demands on society for reconstruction and rehabilitation. In most case, the natural phenomena triggering the disasters are beyond human control. In order to solve the problems that the information resources can not be shared among disaster management sectors and their work is hard to be coordinated in city, an idea of application of ubiquitous sense network and ICT technology to model the architecture of the disaster prevention system based on the analysis of characteristics of disasters. The proposed algorithm simulated that it is possible to locate the terminal by linking the direction angle and the estimated position that can be confirmed at the time of stopping, even if the movement direction of the terminal does not move in a certain direction with only a smaller number of mobile base stations. We also confirmed that the proposed algorithms analyzed through simulation are more efficient than existing algorithms.

• Molecules and Cells
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• v.42 no.1
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• pp.79-86
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• 2019

Endolysins are bacteriophage-derived enzymes that hydrolyze the peptidoglycan of host bacteria. Endolysins are considered to be promising tools for the control of pathogenic bacteria. LysB4 is an endolysin produced by Bacillus cereus-infecting bacteriophage B4, and consists of an N-terminal enzymatic active domain (EAD) and a C-terminal cell wall binding domain (CBD). LysB4 was discovered for the first time as an L-alanoyl-D-glutamate endopeptidase with the ability to breakdown the peptidoglycan among B. cereus-infecting phages. To understand the activity of LysB4 at the molecular level, this study determined the X-ray crystal structure of the LysB4 EAD, using the full-length LysB4 endolysin. The LysB4 EAD has an active site that is typical of LAS-type enzymes, where $Zn^{2+}$ is tetrahedrally coordinated by three amino acid residues and one water molecule. Mutational studies identified essential residues that are involved in lytic activity. Based on the structural and biochemical information about LysB4, we suggest a ligand-docking model and a putative endopeptidase mechanism for the LysB4 EAD. These suggestions add insight into the molecular mechanism of the endolysin LysB4 in B. cereus-infecting phages.

• International Journal of Computer Science & Network Security
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• v.21 no.2
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• pp.110-119
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• 2021

The Coronavirus or COVID-19 is contagiousness virus that infected almost every single part of the world. This pandemic forced a major country did lockdown and stay at a home policy to reduce virus spread and the number of victims. Interactions between humans and robots form a popular subject of research worldwide. In medical robotics, the primary challenge is to implement natural interactions between robots and human users. Human communication consists of dynamic processes that involve joint attention and attracting each other. Coordinated care involves sharing among agents of behaviours, events, interests, and contexts in the world from time to time. The robotics arm is an expensive and complicated system because robot simulators are widely used instead of for rehabilitation purposes in medicine. Interaction in natural ways is necessary for disabled persons to work with the robot simulator. This article proposes a low-cost rehabilitation system by building an arm gesture tracking system based on a depth camera that can capture and interpret human gestures and use them as interactive commands for a robot simulator to perform specific tasks on the 3D block. The results show that the proposed system can help patients control the rotation and movement of the 3D arm using their hands. The pilot testing with healthy subjects yielded encouraging results. They could synchronize their actions with a 3D robotic arm to perform several repetitive tasks and exerting 19920 J of energy (kg.m².S^-2). The average of consumed energy mentioned before is in medium scale. Therefore, we relate this energy with rehabilitation performance as an initial stage and can be improved further with extra repetitive exercise to speed up the recovery process.