• Proceedings of the Plant Resources Society of Korea Conference
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• 2010.05a
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• pp.5-5
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• 2010

Selection of specific medicinal sources as well as bioactive compounds is important for the preparation of medicine and related products with good quality. It is necessary to pay close attention for choosing correct medicinal sources, particularly in case of medicinal plants, because of their diversity, which can affect the quality and efficacy of medicine. Discrimination of plants based on morphological or genetic characteristics has been used as a conventional classification method of pharmaceutical sources so far; however, more need demands more general methods for accurate quality assessment of medicinal plants. In this study, ultra performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF MS) technique applied to this metabolic profiling is a powerful tool due to its higher sensitivity, resolution, and speed compared to conventional HPLC technique. The metabolite profiling of several medicinal plants including Panax ginseng was carried out using UPLC/Q-TOF MS and total metabolites were then subsequently applied to various statistical tools to compare the patterns. The developed metabolomics tool with UPLC/Q-TOF MS successfully identified and classified the samples tested according to their origins.

• Journal of the Korean Society of Physical Medicine
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• v.6 no.1
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• pp.81-92
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• 2011

Purpose : The purpose of this study was to compare combined exercise program group to conventional physiotherapy for patients with chronic neck pain. Methods : Participants were randomly allocated to two groups by experimental(n=17) and control(n=17). Combined exercise program group involved stretching, stability, strengthening and endurance, proprioceptive exercises along with an educational programme. Patient attended for 60min, three times a weeks. Control group was treated as conventional physiotherapy on 40 min, three times a weeks. Outcome variables included pain, disability, range of motion, fatigability at 0 and 6 weeks. Results : Pain, Disability Index, Fatigability significantly decreased(p<.05) and Range of motion improved significantly after active exercise program(p<.05). In conclusion. Combined exercise program improves pain and disability, range of motion, fatigability. Conclusion : These results suggest that combined exercise program is suitable for chronic neck pain.

• Sleep Medicine and Psychophysiology
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• v.2 no.1
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• pp.31-43
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• 1995

Recently, the methods that measure and analyze brain electrical activity quantitatively have been available with the rapid development of computer technology. The quantitative electroencephalography(QEEG) is a method of computer-assisted analyzing brain electrical activity. The QEEG allows for a more sensitive, precise and reproducible examination of EEG data than that can be accomplished by conventional EEG. It is possible to compare various EEG parameters each other by using QEEG. Neurometrics, a kind of the quantitative EEG. is to compare EEG characteristics of the patient with normative data to determine in what way the patient's EEG deviates from normality and to discriminate among psychiatric disorders. Nowadays, QEEG is far superior to conventional EEG in its detection of abnormality and in its usefulness in psychiatric differential diagnosis. The abnormal findings of QEEG in various psychiatric disorders are also discussed.

• BMB Reports
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• v.43 no.12
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• pp.781-788
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• 2010

An often overlooked issue in the field of adenovirus (Ad)-mediated cancer gene therapy is its limited capacity for effective systemic delivery. Although primary tumors can be treated effectively with intralesional injection of conventional Ad vectors, systemic metastasis is difficult to cure. Systemic administration of conventional naked Ads leads to acute accumulation of Ad particles in the liver, induction of neutralizing antibody, short blood circulation half-life, non-specific biodistribution in undesired organs, and low selective accumulation in the target disease site. Versatile strategies involving the modification of viral surfaces with polymers and nanomaterials have been designed for the purpose of maximizing Ad anti-tumor activity and specificity by systemic administration. Integration of viral and non-viral nanomaterials will substantially advance both fields, creating new concepts in gene therapeutics. This review focuses on current advances in the development of smart Ad hybrid nanocomplexes based on various design-based strategies for optimal Ad systemic administration.

• Journal of Biomedical Engineering Research
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• v.21 no.2
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• pp.137-144
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• 2000

Clustered microcalcifications in X-ray mammograms are an important sign for the diagnosis of breast cancer. A shape-based method, which is based on the morphological features of clustered microcalcifications, is proposed for classifying clustered microcalcifications into benign or malignant categories. To verify the effectiveness of the proposed shape features, clinical mammograms were used to compare the classification performance of the proposed shape features with those of conventional textural features, such as the spatial gray-leve dependence method and the wavelet-based method. Image features extracted from these methods were used as inputs to a three-layer backpropagation neural network classifier. The classification performance of features extracted by each method was studied by using receiver operating-characteristics analysis. The proposed shape features were shown to be superior to the conventional textural features with respect to classification accuracy.

• Korean Journal of Bronchoesophagology
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• v.17 no.1
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• pp.29-34
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• 2011

Traditionally, the main strategy of treatment of the head and neck cancer was en bloc resection including adjacent normal tissues through wide incision. However, the procedures may leave severe functional deficit such as swallowing difficulty, aspiration, and wide neck scar. Therefore, many attempts have been made up to minimize these morbidities. Of them, the minimal invasive approach such as transoral laser microsurgery (TLM) and transoral robot surgery (TORS) have been spolighted as a sensible strategy for organ preservation of the head and neck cancer patients. Results of TLM are equivalent to those obtained by conventional surgery, with considerably less morbidity, less hospital time and better postoperative function. Oncologic results of TLM are equivalent to conventional surgery. TORS are safe, feasible, and promising but oncologic safety is not yet verified. This article covers to current application of TLM and TORS, their advantages and limitations, and future direction.

• Korean Journal of Veterinary Research
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• v.54 no.1
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• pp.49-52
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• 2014

This study was conducted to compare the patterns of mastitic pathogens and the antimicrobial susceptibility of Staphylococcus (S.) aureus from conventional milking (CM) and robotic milking (RM) dairy herds. To accomplish this, the minimum inhibitory concentrations of 14 antimicrobial agents were tested against S. aureus by the microdilution method. Regardless of the milking system, S. aureus, coagulase negative staphylococcus, and Streptococcus uberis were isolated. Additionally, significant differences in the antimicrobial susceptibility of S. aureus isolates between RM and CM farms were only observed in response to tetracycline.

• 제어로봇시스템학회:학술대회논문집
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• 1997.10a
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• pp.1528-1535
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• 1997

Many radiological modalities has been applied to medicine as a basic fundamental diagnosis and therapy recently. The prevalence of computer systems affect most images to be digitized. However conventional X-ray film images are not digital images eventhough they covers 70% of all radiologica images. This is the hinderacne of building PACS. In this paper all radiological digital imaging parts such as DSA. CR. MRI. SPECT. PET and ultrasonography were briefly introduced and the applications were described. In brief digital radiography contribute to enhance the medical service quality. And the digital substituition of conventional X-ray film image is inevitable.

• Archives of Plastic Surgery
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• v.45 no.4
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• pp.314-318
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• 2018

Perforator flaps become a reliable option for coverage of various defects and the interest is change from survival of perforator flaps to make thin flaps for better aesthetic and functional outcomes. Multiple flap thinning methods have been demonstrated but it has not been widely attempted because of concerns about compromising circulation of flap thinning. This article will demonstrate the feasibility and benefits of flap thinning technique: defatting after conventional flap elevation.

• Proceedings of the KIEE Conference
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• 1993.07a
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• pp.510-512
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• 1993

The weighted median hybrid filters are proposed. These filters take weighting factors in calculating the output of subfilters of median hybrid filters. The properties of weighted median hybrid filters are analysed and compared to the conventional median filter. The results indicate that these filters preserve details of edge better than and are computationally much more efficient than conventional median filter.