• Asian Pacific Journal of Cancer Prevention
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• 제16권16호
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• pp.6923-6928
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• 2015

Background: Early detection of various kinds of cancers nowadays is needed including colorectal cancer due to the highly significant effects in improving cancer treatment. The aim of this study was to evaluate the potential value of adiponectin, visfatin and resistin as early biomarkers for colorectal cancer patients. Materials and Methods: Serum levels of adiponectin, visfatin and resistin were measured by a sandwich-enzyme-linked (ELISA) assay technique in 114 serum samples comprising 34 patients with colorectal cancer (CRC), 27 with colonic polyps (CP), 24 with inflammatory bowel disease (IBD) and 29 healthy controls. The diagnostic accuracy of each serum marker was evaluated using receiver-operating characteristic (ROC) curve analysis. Results: The mean concentration of adiponectin was significantly higher in CRC and CP groups than IBD and control groups (P-value <0.05). Also the mean concentration of serum resistin was significantly elevated in the IBD and control groups compared to CRC and CP groups (P-value = 0.014). However, no significant difference was noted in patients of the CRC and CP groups. On the other hand, the mean concentration of visfatin was significantly elevated in CRC and control groups compared to CP and IBD groups (P-value = 0.03). ROC analysis curves for the studied markers revealed that between CRC and IBD groups serum level of adiponectin had a sensitivity of 76.7% and a specificity of 76% at a cut off value of 3940, +LR being 3.2 and -LR 0.31 with AUC 0.852, while serum level of adiponectin between CP and IBD had a sensitivity of 77.8% and a specificity of 75% at a cut off value of 3300, with +LR=3.11 and -LR = 0.3 with AUC 0.852. On the other hand the serum level of visfatin between CRC and CP groups had a sensitivity of 65.5% and a specificity of 66.7 at a cut off value of 2.4, +LR being 1.67 and -LR 0.52 with AUC 0.698. Also the serum level of resistin had a sensitivity of 62.5% and a specificity of 70.3% at a cut off value of 24500, with +LR=2.1 and -LR = 0.53 with AUC 0.685 between control and other groups. On the other hand by comparing control vs CP groups resistin had a sensitivity of 81.8% and a specificity of 70.8% at a cut off value of 17700, with +LR=2.8 and -LR = 0.26 with AUC 0.763 while visfatin had a sensitivity of 68.2% and a specificity of 70.8% at a cut off value of 2.7, with +LR=2.34 and -LR = 0.0.45 with AUC 0.812. Conclusions: These findings support potential roles of adiponectin, visfatin and resistin in early detection of CRC and discrimination of different groups of CRC, CP or IBD patients from normal healthy individuals.

• 산업경영시스템학회지
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• 제39권3호
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• pp.10-17
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• 2016

Control Chart is a graph which dots the characteristic values of a process. It is the tool of statistical technique to keep a process in controlled condition. It is also used for investigating the state of a process. Therefore many companies have used Control Chart as the tool of statistical process control (SPC). Products from a production process represent accidental dispersion values around a certain reference value. Fluctuations cause of quality dispersion is classified as a chance cause and a assignable cause. Chance cause refers unmanageable practical cause such as operator proficiency differences, differences in work environment, etc. Assignable cause refers manageable cause which is possible to take actions to remove such as operator inattention, error of production equipment, etc. Traditionally ${\bar{x}}-R$ control chart or ${\bar{x}}-s$ control chart is used to find and remove the error cause. Traditional control chart is to determine whether the measured data are in control or not, and lets us to take action. On the other hand, RNELCC (Reflected Normal Expected Loss Control Chart) is a control chart which, even in controlled state, indicates the information of economic loss if a product is in inconsistent state with process target value. However, contaminated process can cause control line sensitive and cause problems with the detection capabilities of chart. Many studies on robust estimation using trimmed parameters have been conducted. We suggest robust RNELCC which used the idea of trimmed parameters with RNEL control chart. And we demonstrate effectiveness of new control chart by comparing with ARL value among traditional control chart, RNELCC and robust RNELCC.

• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3385-3388
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• 2012

Objective: The study was conducted to assess biochemical profiles in premenopausal and postmenopausal women having breast cancer. Materials and Methods: A hospital based case control study was carried out at Manipal Teaching Hospital (MTH), Pokhara, Nepal. The analysed variables were age, metabolic profile including total cholesterol, triglycerides, HDL-C, LDL-C, blood sugar, insulin concentration, C-peptide, HbA1c and selenium. Descriptive statistics and testing of hypothesis were used for the analysis using EPI INFO and SPSS 16 software. Results: In premenopausal women, significant differences were noted for total cholesterol (P value <0.001), triglycerides (P value 0.002), HbA1c level (P value <0.001), insulin concentration (P value 0.030), C-peptide concentration (P value 0.001), and selenium (P value <0.001) between cases and controls. Insignificant results were found for HDL-C (P value 0.749), LDL-C (P value 0.933), blood sugar (P value 0.59) and BMI (P value 0.746). Similarly, significant difference in total cholesterol (P value <0.001), triglycerides (P value 0.001), LDL-C (P value <0.001), HDL-C (P value 0.025), blood sugar (P value <0.001), insulin concentration (P value <0.001), c-peptide concentration (P value <0.001), HbA1c level (P value <0.001) and selenium (P value <0.001) were observed for postmenopausal patients and controls. Conclusions: Assessing metabolic changes and their management may be important for control of breast cancer and increased survival.

• 식물병연구
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• 제14권2호
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• pp.102-106
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• 2008

Bacillus subtilis QST713(BS QST713)의 단독, 살균제와 혼합 및 교호처리하여 인삼 점무늬병의 방제효과를 검정하였다. BS QST713를 10일 간격으로 단독으로 처리했을 때, 인삼 점무늬병에 대한 방제가는 83.3%, azoxystrobin, chlorothalonil copper sulfate basic, copper sulfate basic, kresoxim-methyl, difenoconazole, mancozeb 단독 처리구는 $80.4{\sim}83.7%$로 나타났다. BS QST713와 mancozeb를 혼합하여 14일 간격으로 처리하였을 때의 방제가는 83.6%, BS QST713와 azoxystrobin 혼합 처리구는 82.6%이었으나, difenoconazole, kresoxim-methyl, copper sulfate basic 및 chlorothalonil copper sulfate basic와 혼합 처리구는 $61.1{\sim}76.4%$로 방제효과가 약간 감소하였다. 대전에서 BS QST713와 copper sulfate basic를 10일 간격으로 교호처리시 방제가가 85.9%이었으나, 다른 살균제와의 교호처리 시는 $55.5{\sim}78.2%$로 낮아 졌다. 그러나 무주에서 모든 교호처리에서 방제가가 90% 이상으로 나타났다. 이상의 결과에 의하면 BS QST713의 단독, 혼합 및 교호처리는 살균제의 사용량을 줄일 수 있는 방제법으로 이용될 것이다.

• 한국식품조리과학회지
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• 제19권1호
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• pp.114-120
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• 2003

The purpose of this study was to investigate the effects of the addition of various amounts (0, 1, 3, 5%) of Mokdanpi(P. suffruticosa) powder on the shelf life and the physicochemical, sensory characteristics of rice cakes and noodles to examine the possibility of using Mokdanpi as a natural food preservative for food products. The decrease in the moisture content of rice cake and noodle samples during storage was much less in Mokdanpi-added groups than the control group. The color L value increased and a and b values decreased in the rice cake samples, and color L value, b value decreased and a value increased in the noodle samples during storage. The microbial growth was less in Mokdanpi-added groups than the control group. In sensory evaluation, there were no significant differences among the control and 1, 3%-added groups in terms of color, flavor, taste, moistness, cohesiveness and overall quality; however, 5%-added groups received significantly less score than others (p＜0.05). As the storage time increased, the sensory scores decreased significantly in the control and 1 %-added groups of both rice cakes and noodles (p＜0.05), but no changes were observed in 3, 5%-added samples. The results suggested that Mokdanpi is effective in increasing the shelf life and inhibiting the staling of rice cakes and noodles.

• 한국산학기술학회논문지
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• 제8권6호
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• pp.1402-1409
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• 2007

본 논문에서는 시스템 구현에 직접적으로 사용될 수 있는 직교 주파수 분할 다중화 (OFDM : Orthogonal Frequency Division Multiplexing) 통신 시스템을 위한 여러 가지 자동 이득 제어 (AGC : Automatic Gain Control) 알고리듬을 제안하고자 한다. 본 논문에서는 고속 패킷 전송을 위하여 비교적 많은 샘플 수를 갖고 긴 길이의 프리앰블을 반복적으로 사용하는 초 광대역 통신 (UWB : Ultra-Wideband)과 같은 OFDM 시스템의 디지털 수신 신호를 가정한다. 이러한 OFDM 시스템에서는 프리앰블 신호를 아날로그-디지털 변환기 (ADC : Analog-to-Digital Converter)를 통해 디지털 수신 신호로 변환한 후 최대 샘플 값 계수기내 버퍼의 길이만큼 디지털 수신 신호를 저장한다. 이 후 버퍼에 저장된 디지털 수신 신호 중 최대 샘플의 개수를 계산하고 이득 조절 신호 발생기에 저장된 이득 조절 테이블에 따라 이득을 조절하여 ADC 입력단의 전력 레벨을 자동으로 조절한다.

• Journal of Advanced Marine Engineering and Technology
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• 제28권6호
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• pp.906-915
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• 2004

In this paper, we address the development of magnetic levitation positioning system. This planar magnetic levitator employs four permanent magnet liner motors. Each motor generates vertical force for suspension against gravity, as well as horizontal force for driving levitation object called a platen. This stage can generate six degrees of freedom motion by the vertical and horizontal force. We derived the mechanical dynamics equation using Lagrangian method and used coenergy to express an electromagnetic force. We proposed a control algorithm for the position and posture control from its initial value to its desired value using sliding mode control. Some simulation results are provided to verify the effectiveness of the proposed control scheme.

• 한국안전학회지
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• 제18권1호
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• pp.44-49
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• 2003

Permanent magnet synchronous motor(PMSM) is widely used in many applications such as an electric vehicle. compressor drives of air conditioner and machine tool spindle drives. PMSM drive system have become a popular choice in various application, due to their excellent power to weight ratio. This paper is proposed maximum torque control for field weakening operation of PMSM drive. At low speeds, the reluctance torque is used to maximize the output for a given current level. This is achieved maximum torque per ampere(MTPA) by selecting an optimal value of the direct stator current component. At high speeds, the system reaches a point at which the inverter will not be able to supply the desired voltage. In this case it is necessary to make use of an increased value the direct current component. The proposed control algorithm is applied to PMSM drive system, the operating characteristics controlled by maximum torque control are examined in detail by simulation.

• 한국정밀공학회지
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• 제15권2호
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• pp.75-80
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• 1998

Process information is known to have the continuous distribution in many manufacturing processes. Generalized p-chart has been developed for controlling processes by classifying the information characteristics into several groups. But it is improper to describe continuous processes with the classified process informal ion, which is based on the classical set concept. Fuzzy control chart, has been developed for the control of linguistic data, but it is also based on the dichotomous notion of classical set theory. In this paper, fuzzy sampling method is studied in order to process the uncertain data properly. The method is incorporated with the fuzzy control chart. Statistical characteristics of the fuzzy representative value are utilized to device the fuzzy-statistical control chart. The fuzzy-statistical control chart is compared with the generalized p-chart and both the sensitivity to the process information distribution change pared robustiness against the noise on the process information of the fuzzy-statistical control chart are shown to be superior.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1999년도 하계학술대회 논문집 C
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• pp.1070-1072
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• 1999

Automatic Generation Control(AGC) is a control system whose objectives are to hold system frequency close to a specified nominal value and to maintain each unit's generation at the most economic value. It has been used to control the output of a generator by the control signal of the generator, but it is not appropriate to apply to generators which adopt the distributed control system. In this paper a method for improving the AGC operation is proposed, and the different response of each generator and various types of control systems of generators are considered. The interface among Remote Terminal Detector(RTU) and control systems and the direct delivery of the data between EMS and DCS also are proposed in the paper.