• Title/Summary/Keyword: control surface damage

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Flood Characteristics at Nakdong Estuary with 1 Dimensional Unsteady Model (1차원 부정류 모형을 활용한 낙동강 하류의 홍수 특성)

  • Lee, Sang-jin;Shin, Hyun-Ho;Kim, Joo-Cheol;Hwang, Man-Ha
    • Journal of Environmental Science International
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    • v.19 no.2
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    • pp.149-155
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    • 2010
  • Rainfalls would increase the discharges or stages of tributary channels in natural watersheds, which in turn augment the magnitude of main stream stages. Rising of water surface elevation in main streams can affect and damage the human activities because of the possibilities of the breakdown or overflow of the embankment. Therefore it is necessary to establish the structural or non-structural alternatives for the sake of prevention or treatment of those disasters. Many mathematical models to analyze the flood flows in natural watercourses have been proposed as the non-structural alternatives so far. In this study one of the such models, FLDWAV developed by NWS(National weather Service), is applied to the downstream reach of Nakdong river. Model calibration is performed on various Manning's roughness coefficients at the gauging stations. The simulation results are compared well with hydrological estimations of flood discharges considering the effects of multipurpose dams upstream of control points.

Mechanisms and Physiological Roles of Mitophagy in Yeast

  • Fukuda, Tomoyuki;Kanki, Tomotake
    • Molecules and Cells
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    • v.41 no.1
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    • pp.35-44
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    • 2018
  • Mitochondria are responsible for supplying of most of the cell's energy via oxidative phosphorylation. However, mitochondria also can be deleterious for a cell because they are the primary source of reactive oxygen species, which are generated as a byproduct of respiration. Accumulation of mitochondrial and cellular oxidative damage leads to diverse pathologies. Thus, it is important to maintain a population of healthy and functional mitochondria for normal cellular metabolism. Eukaryotes have developed defense mechanisms to cope with aberrant mitochondria. Mitochondria autophagy (known as mitophagy) is thought to be one such process that selectively sequesters dysfunctional or excess mitochondria within double-membrane autophagosomes and carries them into lysosomes/vacuoles for degradation. The power of genetics and conservation of fundamental cellular processes among eukaryotes make yeast an excellent model for understanding the general mechanisms, regulation, and function of mitophagy. In budding yeast, a mitochondrial surface protein, Atg32, serves as a mitochondrial receptor for selective autophagy that interacts with Atg11, an adaptor protein for selective types of autophagy, and Atg8, a ubiquitin-like protein localized to the isolation membrane. Atg32 is regulated transcriptionally and post-translationally to control mitophagy. Moreover, because Atg32 is a mitophagy-specific protein, analysis of its deficient mutant enables investigation of the physiological roles of mitophagy. Here, we review recent progress in the understanding of the molecular mechanisms and functional importance of mitophagy in yeast at multiple levels.

A Study on the Soluble Salt and Deterioration of Ceramics from Taean Shipwreck (태안 마도 출토 도자기의 염에 의한 손상상태 연구)

  • Jang, Sung-Yoon;Nam, Byeong-Jik;Park, Dae-Woo;Kang, Hyun-Mi;Jung, Yong-Hwa
    • 보존과학연구
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    • s.30
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    • pp.189-202
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    • 2009
  • Ceramics from Taean shipwreck were studied to investigate the deterioration by soluble salts and desalination pattern according to each ceramic characterization. NaCl crystals were found as a crystal growth on the ceramic microstructure and deteriorated to push off the glaze layer of some Puncheong ware sample. As a result of monitoring the desalination pattern of ceramics for 74days, the earthenware sample with big pores and no glaze removed soluble salts so fast, but Puncheong ware and Whiteware samples removed lots of soluble salts slowly and continuously. Generally, it takes long time to remove soluble salts from porcelains, due to small pores and glaze, but the long-term desalination probably can cause the damage on the surface layer such like glaze. As some soluble salts still remains in the ceramic microstructures after desalination, it is very important to control and keep the relative humidity stable through the proper storage. There are various ceramic deterioration patterns by soluble salts. Therefore, it needs to select the desalination method of ceramics from shipwreck, considering the material characteristics and the production techniques.

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Effects of Low and Moderate Intensity Treadmill Exercise on Functional Recovery and Histological Changes After Spinal Cord Injury in the Rats (척수손상 백서모델에서 저강도 및 중강도 트레드밀 운동이 운동기능회복 및 조직학적 변화에 미치는 영향)

  • Kim, Gi-Do;Kim, Gye-Yeop;Kim, Eun-Jung
    • Physical Therapy Korea
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    • v.16 no.2
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    • pp.41-49
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    • 2009
  • This study was designed to investigate the effects of treadmill exercise of low-intensity and moderate- intensity on the functional recovery and histological change in spinal cord injury (SCI) rats. SCI was induced by the spinal cord impactor dropped after laminectomy. Experimental groups were divided into the Group I (normal control), Group II (non-treatment after SCI induction), Group III (low-intensity treadmill exercise after SCI induction), Group IV (moderate-intensity treadmill exercise after SCI induction). After operation, rats were tested at modified Tarlov scale at 2 days with divided into 4 groups, and motor behavior test (BBB locomotor rating scale, Grid walk test) was examined at 3, 7, 14, and 21 days. For the observation of damage change and size of the organized surface in spinal cord, histopathological studies were performed at 21 days by H & E, and BDNF(brain-derived neutrophic factor) & Trk-b immunohistochemistry studies were performed at 1, 3, 7, 14, 21 days. According to the results, treadmill exercise can play a role in facilitating recovery of locomotion following spinal cord injury. Specially, moderate-intensity treadmill exercise after SCI induction was most improvement in functional recovery and histological change.

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Inverted OLED Structure for 3.5 inch Full Color AMOLED Display on a-Si TFT Backplane

  • Park, Jae-Hee;Park, Jae-Young;Hwang, Kwang-Jo;Choi, Hee-Dong;Myoung, Nho-Hoon;Lee, Seok-Jong;Park, Seung-Chul;Kim, Jung-Bum;Hahm, Yun-Hye;Noh, Jeoung-Kwen;Lee, Jung-Hyoung;Kim, Jong-Seok;Kang, Min-Soo
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08a
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    • pp.51-54
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    • 2007
  • Top-emission 3.5 inch qVGA IOD (Inverted AMOLED) was fabricated with inverted EL structure driven by a-Si TFT backplane. In order to get stable driving TFT, we used FCP(Field Control Plate) layer which was connected with the source of the driving TFT. And we developed planarization process to planarize the cathode layer which was the bottom layer of inverted OLED. Our unique IOD structure is “a-Si TFT/ Al(Cathode)/ LiF/ LG-201(ETL)/ EML(RGB)/ HTL/ LG-101(HIL & Buffer layer)/ IZO(Anode)”. LG-201(ETL) layer was studied for more efficient electron injection from cathode to EML, and LG-101(HIL & Buffer layer) covered by IZO anode was also explored for decreasing the EL surface damage.

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Prediction of Erosion Rate in Passages of a Turbine Cascade with Two-Phase flow (터빈익렬 유로에서 2상 유동에 따른 삭마량 예측)

  • Yu, Man Sun;Kim, Wan Sik;Cho, Hyung Hee
    • 유체기계공업학회:학술대회논문집
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    • 1999.12a
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    • pp.301-308
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    • 1999
  • The present study investigates numerically particle laden flow through compressor cascades and a rocket nozzle. Engines are affected by various particles which are suspending in the atmosphere. Especially in the case of aircraft aviating in volcanic, industrial and desert region including many particles, each components of engine system are damaged severely. That damage modes are erosion of compressor blading and rotor path components, partial or total blockage of cooling passage and engine control system degradation. Numerical prediction and experimental data, erosion rates are predicted for two materials - ceramic, soft metal - on compressor blade surface. Aluminum oxide ($Al_2O_3$) Particles included in solid rocket propelant make ablative the rocket motor nozzle and imped the expansion processes of propulsion. By the definition of particle deposition efficiency, characteristics of particles impaction are considered quantitatively Stoke number is defined over the various particle sizes and particle trajectories are treated by Lagrangian approach. Particle stability is considered by definition of Weber number in rocket nozzle and particle breakup and evaporation is simulated in a rocket nozzle.

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Effects of Hominis Placenta Pharmacopuncture and Electroacupuncture Neuroprotection in Contused Spinal Cord of Rats (척수손상 흰쥐에서 자하거 약침과 침전기 자극이 신경성장인자 발현에 미치는 영향)

  • Kim, Eun-Jung;Kim, Gye-Yeop
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.25 no.2
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    • pp.257-263
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    • 2011
  • This study was designed to investigate the effects of Hominis placenta pharmacopuncture treatment and electroacupuncture therapy on the functional recovery and histological change, protein expression in spinal cord injury(SCI) rats. Experimental groups were divided into the Group I(normal control rat), Group II(Non-treatment after spinal cord injury induction), Group III(Hominis placenta pharmacopuncture treatment after SCI induction), Group IV (Electroacupuncture therapy after SCI induction), Group V(Hominis placenta pharmacopuncture treatment and electroacupuncture therapy after SCI induction). After operation, rats were tested at modified Tarlov test at 1 to 3 days with divided into 4 groups, and motor behavior test(BBB locomotor rating scale, Grid walk test) was examined at 3, 7, 14, and 21 days. For the observation of damage change and size of the organized surface in muscle and spinal cord, histopathological studies were performed at 21 days by H & E stain, and BDNF & NT-3 protein expression studies were performed at 21 days. Acco rding to the results, Hominis placenta pharmacopuncture treatment and electroacupuncture therapy can play a role in facilitating recovery of locomotion following spinal cord injury. Specially, Hominis placenta pharmacopuncture treatment and electroacupuncture combimed therapy after SCI induction was most improvement in functional recovery, BDNF, and NT-3 protein synthesis.

Effect of Waterlogging Duration on Growth Characteristics and Productivity of Forage Corn at Different Growth Stages Under Paddy Field Conditions

  • Jung, Jeong Sung;Choi, Gi-Jun;Choi, Bo-Ram
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.39 no.3
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    • pp.141-147
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    • 2019
  • The purpose of this study was to determine the effect of waterlogging duration on the growth characteristics and productivity of forage corn at different growth stages under paddy field conditions. Treatments consisted of waterlogging at two growth stages (V7 or V14) for four waterlogging durations (no waterlogging, 48 hours, 72 hours, and 96 hours, respectively). The V14 growth stage was more vulnerable to waterlogging than the V7 stage. Among the waterlogging durations, the lodging score increased at 48 hours. The stem height of forage corn decreased with the increase in waterlogging duration at the different growth stages (V7 and V14). Increase in waterlogging duration reduced the stem dry matter yield, ear dry matter yield, and total dry matter yield at both growing stages (V7 and V14). The waterlogging treatments at the V14 stage affected ear dry matter yield more than those at the V7 growing stage. Thus, the management of forage corn under paddy field conditions must be strengthened during early (V7) and grain fill stages (V14). When waterlogging occurs, surface and subsurface drainage should be implemented within 48 hours to control (no waterlogging) the groundwater level and, thus, minimize economic losses due to forage corn damage.

A Comparative Evaluation of Closed and Open Kinetic Exercises in the Management of Chronic Ankle Instability

  • Jung, Namjin
    • Journal of International Academy of Physical Therapy Research
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    • v.11 no.4
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    • pp.2212-2220
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    • 2020
  • Background: Repetitive damage to the ankle joint causes chronic ankle instability, and studies comparing the effects of exercise in open and closed chains as a treatment method are very rare. Objectives: To investigate the effects of open and closed kinetic exercises on muscle activity and dynamic balance of ankle joint in adults with chronic ankle instability. Design: Single-blind randomized controlled trial. Methods: The selected 30 subjects are randomly divided into open kinetic chain exercise experimental group (EGI, n=10), closed kinetic chain exercise experimental group (EGII, n=10), and stretching control group (CG, n=10). Open and closed kinetic exercises lasted 30 minutes three times a week for six weeks and stretching exercises performed four actions for 20 seconds and five sets. The measurement tools using surface electromyography to measure muscle activity in the ankle joint. The dynamic balance of the ankle was evaluated using the Y-Balance test. Results: Following the intervention, closed and open kinetic chain exercise group showed significant difference in tibialis anterior and gastrocnemius muscle activity and dynamic balance (P<.05). However, no significant difference in tibialis anterior and gastrocnemius muscle activity and dynamic balance between closed and open kinetic chain exercise group (P<.05). Conclusion: This study provides evidence that closed and open kinetic chain exercise can be presented as an effective exercise for the muscle activity of ankle muscle and dynamic balance of the subject with chronic ankle instability.

Effect of antibodies binding to Y chromosome-bearing sperm conjugated with magnetic nanoparticles on bull sperm characteristics

  • Jo, So-Yeon;Hwangbo, Yong;Lee, Sang-Hee;Cheong, Hee-Tae;Kim, Dong-Ku;Park, Choon-Keun
    • Journal of Animal Reproduction and Biotechnology
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    • v.36 no.4
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    • pp.239-246
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    • 2021
  • The immunological sperm separation method is economical compared to the existing sorting method, and it is promising for the development of new technologies by reducing sperm damage. Wholemom (WM) is a sex-regulating protein that comprises on immunoglobulin G coupled with magnetic nanoparticles (MNPs) that responds to surface proteins derived from the Y chromosome in cattle. Y sperms are restricted in motility as the WM aggregates them, and the magnet could separate the non-aggregated cells. This study was conducted to investigate the effect of WM treatment on the characteristics of bull sperm. After treating sperm with WM and incubation for 6 h, the motility parameters including total motility, progressive motility, velocity average path, velocity straight line, amplitude of lateral head displacement, and linearity were significantly higher in the WM treatment group than in the control group (p < 0.05). Sperm viability and acrosome reaction rates were similar in both groups during each incubation period (p > 0.05). In conclusion, the immunological sperm sexing procedure using a monoclonal antibody conjugated with MNPs did not affect the characteristics of bull sperm. This study suggests that compared to other techniques, the immunological method for sperm sexing could classify sperm quickly and efficiently without the use of expensive equipment.