• Asian Pacific Journal of Cancer Prevention
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• v.15 no.22
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• pp.9949-9953
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• 2014

Objective: To evaluate the long term results among patients with soft tissue sarcoma of the thoracic wall. Materials and Methods: Twenty-six patients who were treated with pre-or postoperative radiotherapy between December 1980-December 2007, with a diagnosis of soft tissue sarcoma of the thoracic wall were retrospectively evaluated. Results: The median age was 44 years (14-85 years) and 15 of them were male. A total of 50% of patients were grade 3. The most common histologic type of tumor was undifferentiated pleomorphic sarcoma (26.9%). Tumor size varied between 2-25 cm (median 6.5 cm). Seventeen of the cases had marginal and 9 had wide local resection. Four cases received preoperative radiotherapy and 22 postoperative radiotherapy. Six of the patients with large and high grade tumors received chemotherapy. Median follow-up time was 82 months (9-309 months). Local recurrence and metastasis was detected in 34.6% and 42.3% of patients, respectively. Five-year local control (LC), disease-free survival (DFS), overall survival (OS), and disease-specific survival (DSS) were 62%, 38%, 69%, and 76% respectively. On univariate analysis, the patients with positive surgical margins had a markedly lower 5-year LC rate than patients with negative surgical margin, but the difference was not significant (43% vs 78%, p=0.1). Five-year DFS (66% vs 17%) and DSS (92% vs 60%) rates were significantly worse for the patients who had high grade tumors (p=0.01, p=0.008 respectively). Conclusions: Tumor grade and surgical margin are essential parameters for determining the prognosis of thoracic wall soft tissue sarcoma both in our series and the literature.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7635-7638
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• 2013

Background: Sperm-associated antigen 9 (SPAG9) has been recently proposed as a novel biomarker for early diagnosis of several human tumors, including ovarian, cervical and breast cancers. Its clinical value remains to be clarified for endometrial cancer (EC). In this study, we investigated the utility of serum SPAG9 levels in diagnosis of EC and its association with important clinicopathological parameters. Materials and Methods: This cross-sectional study was performed at a tertiary women's referral center in Ankara, Turkey. Preoperative serum samples were collected from patients surgically treated for endometrial cancer between June 2012-April 2013. Similar aged women with a biopsy proven benign endometrium were used as controls. Serum SPAG9 levels were measured with an enzyme-linked immunosorbent assay (ELISA) method and assessed for links with clinicopathological factors. Receiver operating characteristic (ROC) curve analysis was performed to assess power of SPAG9 levels for EC prediction. P values less than 0.05 were considered statistically significant. Results: A total of 63 women with EC and 27 with benign endometrium were included in the study. Mean age in the EC group was $58.7{\pm}1.1$. Median SPAG9 levels in the EC and control groups were 18.3 (range, 12.7-53.8) and 14.1 (range, 4.3-65.3), respectively (p<0.001). A cut-off value of 17 ng/ml for SPAG9 predicted presence of malignant endometrium with 74% sensitivity and 83% specificity [Area under curve (AUC)=0.82, p<0.001]. SPAG9 levels did not demonstrate any significant association with histological type, FIGO stage, tumor grade, size, myometrial invasion, lymphovascular space invasion, cervical involvement, adnexal involvement, peritoneal cytology or lymph node status (all p>0.05). Conclusions: Testing for SPAG9 may be useful for early detection of EC in asymptomatic high-risk women. Its role in post-treatment follow-up and early detection of recurrence should be assessed in future trials.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.6
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• pp.3983-3989
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• 2014

As the storm water runoff characteristics in urban areas have changed owing to urbanization, centralized facilities to reduce the urban flood runoff had been implemented. On the other hand, because they have their limitations, LID (Low Impact Development) of the distributed facilities for storm water runoff reduction is being actively planned and applied. The purpose of this study was to analyze the runoff characteristics for the spatial distribution of typical LID element techniques. This study set a study basin consisting of the five subbasins with the same basin and drainage systems, and analyzed the flood runoff characteristics from the two scenarios, one is for the locations and the other is for the number of green roofs (GR) and permeable pavement (PP), respectively, selected as typical LID element techniques. The SWMM implementation results showed that GR reduces 11.07% of the total and 3.42% of the peak amounts of storm water runoff, and PP leads to 18.09% of the total and 17.94% of the peak discharge reduction for a subbasin. Such a reduction rate is constant regardless of the LID locations, and increases linearly with the number of LID applications. The different runoff reduction rates between the GR and PP applications appear to be due to the effects of the different hydraulic conductivities in the control parameters for each LID.

• Journal of Nutrition and Health
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• v.23 no.2
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• pp.124-134
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• 1990

To investigate nutritional and growth status of premature infants, survey was conducted against 19 premature infants admitted to Nursery of Pediatrics, Young nam University Hospital from Jan. 1984 to July 1988. Variations in feeding patterns as analyzed through the five feeding phases of dextrose, dextrose/hyperal, dextrose/formula, dextrose/hyperal/formula and formula. During 30days from birth, dietary intake, feeding phase, selective anthropometric measurements, biochemical parameters and demograpic information of premature infants were as follows: Distributions of birth weight by gestational age and apgar score showed preamture infants below 1499g were 31 weeks, 4/7(1min/5min) and premature infants from 1500g to 1999g were 33 weeks, 8/9(1min/5min) and premature infants from 2000g to 2500g were 33 weeks, 8/9(1min/5min). Average calorie intakes of premature infants below 1499g, premature infants from 1500g to 1999g and premature infants from 2000g to 2500g were 102.0㎉/kg/day, 119.3㎉/kg/day and 101.7㎉/kg/day. The mean values Na, K, Ca, P for all premature infants remained within the normal level for full term infants throughtout the 25days of this study period. Percentages of inital weight loss showned premature infants below 1499g were 5.4%, premature infants from 1500g to 1999g were 6.4%, premature infants from 2000g to 2500g were 11.4%. Percentages of inital weight loss of the amino acid injection group and the amino acid control group were 9.4% and 9.0%.

• Journal of Korean Society for Atmospheric Environment
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• v.34 no.2
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• pp.269-280
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• 2018

This paper reports the results of field evaluation to determine the levels of heavy metals in major industrial complexes in Korea over a seven year period (2007~2013). The measurement of heavy metal was conducted using quartz fiber filter sampling and ICP-AES analysis. In order to validate the analytical performance of these methods, studies were also carried out to investigate data quality control(QC) parameters, such as the method detection limit (MDL), repeatability, and recovery efficiencies. The average concentrations of total suspended particulates (TSP) for the nine industrial complexes in Korea were $104{\sim}169{\mu}g/m^3$, which was higher than other industrial complexes and urban areas. The Sihwa and Banwol industrial complexes were shown to be the biggest contributing sources to high TSP emission ($159{\mu}g/m^3$ and $169{\mu}g/m^3$, respectively). The concentrations of heavy metals in TSP were higher in the order of Fe>Cu>Zn, Pb, Mn>Cr, Ni, As and Cd. It was observed that Fe was the highest in the Gwangyang and Pohang steel industrial complexes. The concentrations of Zn and Pb were high in Onsan, Sihwa and Banwol industrial complexes, and this was attributed to the emission from the nonferrous industry. Additionally, Cr and Ni concentrations were high in the Sihwa and Banwol industrial complexes due to plating industry. On the other hand, Ulsan and Onsan industrial complexes showed high Cr and Ni concentrations as a response to the emission of metal industry related to automobile. The correlation analysis revealed the high correlation between Cr and Ni in plating industry from Sihwa and Banwol industrial complexes. Adding to this, components related to coal combustion and road dust showed high correlation in Pohang and Gwangyang industrial complexes. Then Onsan and Ulsan industrial complexes showed high correlation among components related to the nonferrous metals.

• Microbiology and Biotechnology Letters
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• v.36 no.2
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• pp.135-141
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• 2008

Immunomodulating effect of Salicornia herbacea extract on the mouse splenocytes was investigated. Crude S. herbacea polysaccharide extract (CSP) and other kinds of fine S. herbacea polysaccharides (SPI and SPII) were prepared from S. herbacea by hot water extraction and further ultrafiltration and gel filtration chromatography. In vitro experiment, the mouse splenocytes and separated T cells were treated with CSP, SPI or SPII (0.5, 1, 2, 4 mg/ml). In vivo experiment, three different S. herbacea extracts were orally administrated everyday for one week. For the basic data, body weight and physiological parameters such as organ weight and spleen index were observed. The proliferation of the cells was used as an index for immunemodulating activity and the effect of proliferation was evaluated using MTS assay. The CSP, SPI and SPII directly induced the proliferation of splenocytes and separated T cells in a dose-dependent manner. In results, the proliferation was more increased in the SPI and SPII treated cells than in the CSP treated cells. The best proliferation was shown in the splenocytes cultured with SPI at the concentration of 4 mg/ml for 24 hr. The proliferation of splenocytes and separated T-cells was higher (3.2 and 3.5 times, respectively) than the control. Moreover, when the mouse splenocytes were treated with mitogen, the efficient proliferation was shown in the splenocytes cultured with SPI. In conclusion, polysaccharides from S. herbacea showed a substantial immunomodulating activity in the mouse immune cells.

• Journal of Korean Society of Environmental Engineers
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• v.31 no.5
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• pp.358-363
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• 2009

The HSPF (Hydrological Simulation Program-Fortran) model was applied to the Kyoungan stream watershed to analyze effects of watershed management plans on receiving water qualities. Utilizing BASINS 3.1 GIS program, the Kyoungan stream watershed was divided into 57 sub-basins and model input parameters were obtained, from DEM (Digital Elevation Model), land use type, stream map, and wastewater treatment facilities, etc.. The hydrologic module of the model was validated based on the measured meteorological data and stream flow data. Then the model was calibrated and verified against the field measurements of water qualities, including temperature, DO, BOD, $NO_3-N$, $NH_3-N$, Org-N, TN and TP. In most cases, there were reasonable agreements between measurements and predictions. The validated model was used to analyze the water quality improvements in the main stream of Kyoungan stream according to the watershed management plans in sub-basins, which are three different scenarios: water quality improvement in tributaries through watershed management activities, expansion and up-grade of wastewater treatment plants, and application of first and second scenarios together. It was concluded that expansion and upgrade of wastewater treatment plants would be more effective than watershed management activities. In order to improve water qualities to the satisfactory level, both watershed management and point source control must be required in the Kyoungan stream.

• The Transactions of the Korea Information Processing Society
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• v.3 no.2
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• pp.283-294
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• 1996

To operate the automatic devices of manufacturing process more effectively and to solve the needs of the resource sharing, network technology is applied to the unit control devices located in common manufacturing zone and operated by connecting them. This paper introduces deign and test operation of cell system for the management of multivendor PLC by applying to wall paper process based on the manufacturing standardization of CIM. The analysis of designed multivendor PLC group is performed by selecting the parameters such as variation of data packet size and node number of PLC ladder logic program and variation by analyzing the corresponding variation values of token rotation time and waiting time for the system operation. For the method of the analysis,the equation is considering the overhead such as indicated packet service time and transmission safety margin for PLC network connection in M/G/1 queue model,and it is applied to the cell system and PLC group manage-ment for operation .Through the experiment,it is found that the realtime processing is possible with expanded and better result than the resuit obtained by Jayasumana.Browaka with PLC scan time considered,response lower limit of 10-20 msec. data packet size not more than 50 bytes.and the number of nodes less than 40.

• Korean Chemical Engineering Research
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• v.58 no.4
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• pp.588-595
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• 2020

Prediction and control of nitrogen oxides (NO_x) emission is of great interest in industry due to stricter environmental regulations. Herein, we propose an artificial intelligence (AI)-based framework for prediction of NO_x emission. The framework includes pre-processing of data for training of neural networks and evaluation of the AI-based models. In this work, Long-Short-Term Memory (LSTM), one of the recurrent neural networks, was adopted to reflect the time series characteristics of NO_x emissions. A decision tree was used to determine a time window of LSTM prior to training of the network. The neural network was trained with operational data from a heating furnace. The optimal model was obtained by optimizing hyper-parameters. The LSTM model provided a reliable prediction of NO_x emission for both training and test data, showing an accuracy of 93% or more. The application of the proposed AI-based framework will provide new opportunities for predicting the emission of various air pollutants with time series characteristics.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.7B
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• pp.685-696
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• 2004

Real-time multimedia applications that require large amount of bandwidth need resource reservation before starting service for providing the QoS(i.e., Quality of Service). To reserve resources in advance, each reservation request has to notify its expectation on the required amount of resources and service duration. Using this information, a resource manager can schedule advance reservations. However, most existing resource management systems are adopting straightforward call admission control process (i.e., only immediate reservation) by checking currently available resources without considering the service duration. Hence, the resource management system that supports advance reservation has to manage confliction caused by indefinite service duration of immediate reservation. Even though the separation of resource pool according to type of reservation can prevent the confliction, it causes low resource utilization. In this paper, we propose an effective resource management scheme that supports both immediate and advance reservations by sharing resources dynamically. Using network cost function, the proposed scheme determines and adaptively adjusts resource boundary according to the confliction rate by varying weight parameters. And also, we define user utility function to quantify user satisfaction based on how well the reserved resource is guaranteed during service time. Simulation results using NS-2 network simulator show that the proposed scheme can achieve better resource utilization with preferable QoS than other schemes like static resource partitioning.