• Journal of the korean society of oceanography
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• 제32권1호
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• pp.28-37
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• 1997

Two marine bivalve shells were collected from the eastern and western coastal regions of Korea, respectively. Stable oxygen and carbon isotope profiles are constructed using the incremental sampling along the axis of maximum growth to provide the continuous ${\delta}^{18}$O and ${\delta}^{13}$C records, which register the physical, biological and chemical properties of seawater where the organisms live. Cycles in the ${\delta}^{18}$O profiles are interpreted as annual along with the identification of annual growth bands; the maximum ${\delta}^{18}$O values correspond with the coldest temperature of seawater whereas the minimum ${\delta}^{18}$O values with the warmest temperature. The primary control on the amplitude of the ${\delta}^{18}$O profiles is seasonal variation of seawater temperature. The offset of the baseline between ${\delta}^{18}$O values of the two specimens is attributed to differences in both temperature and seawater ${\delta}^{18}$O values between two localities. The ${\delta}^{13}$C profiles show the similar seasonality of carbon cycling associated with phytoplankton productivity. The offset in the ${\delta}^{13}$C profiles between two specimens may be, as in the case of oxygen isotope profile, attributed to the different ${\delta}^{13}$C value of the seawater DIC (dissolved inorganic carbon) between the western coast and the eastern coast. Relationships between the shell isotopic composition and the coastal water properties of shell growth are readily interpreted from the ${\delta}^{18}$O-${\delta}^{13}$C pair diagram of the shell isotope data, similar to the use of salinity-${\delta}^{18}$O diagram for identifying water masses. The preliminary stable isotope results of this study suggest that mollusk shell isotope geochemistry may be useful to monitor the properties of water masses in the coastal and inner shelf setting around Korea and improve the interpretation of paleoceanography, provided the fossil mollusks are well preserved.

• 식품과학과 산업
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• 제54권3호
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• pp.184-195
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• 2021

Smart HACCP is a system that can check the monitoring of critical control point (CCP) in real time to implement improvement measures immediately after departure from limit criteria and prevent falsification of data by digitizing handwritten records. In this study, we developed the analysis model for the effectiveness ofsmart HACCP to compare and analyze with existing HACCP. By introducing of smart HACCP system, the evaluation index value of HACCP effectiveness for HACCP-certificated companies on a small scale increased by 9.25 points, corresponding to 11.52% of increase rate. General HACCP-certificated companies showed 4.52 point and 5.00% of increase rate by introducing of smart HACCP system. Thus, it was confirmed that the introduction of smart HACCP system contributes to the improvement of food safety management and especially it would be more effective for HACCP-certificated companies on a small scale than general HACCP-certificated companies.

• Animal Bioscience
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• 제36권7호
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• pp.1010-1021
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• 2023

Objective: Growth performance and growth-related traits have a crucial role in livestock due to their influence on productivity. This genome-wide association study (GWAS) in Pakistani dromedary camels was conducted to identify single nucleotide polymorphisms (SNPs) associated with growth at specific camel ages, and for selected SNPs, to investigate in detail how their effects change with increasing camel age. This is the first GWAS conducted on dromedary camels in this region. Methods: Two Pakistani breeds, Marecha and Lassi, were selected for this study. A genotyping-by-sequencing method was used, and a total of 65,644 SNPs were identified. For GWAS, weight records data with several body weight traits, namely, birthweight, weaning weight, and weights of camels at 1, 2, 4, and 6 years of age were analysed by using model-based growth curve analysis. Age-specific weight data were analysed with a linear mixed model that included fixed effects of SNP genotype as well as sex. Results: Based on the q-value method for false discovery control, for Marecha camels, five SNPs at q<0.01 and 96 at q<0.05 were significantly associated with the weight traits considered, while three (q<0.01) and seven (q<0.05) SNP associations were identified for Lassi camels. Several candidate genes harbouring these SNP were discovered. Conclusion: These results will help to better understand the genetic architecture of growth including how these genes are expressed at different phases of their life. This will serve to lay the foundations for applied breeding programs of camels by allowing the genetic selection of superior animals.

• 동의신경정신과학회지
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• 제34권2호
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• pp.83-94
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• 2023

Objectives: To investigate the correlation of anxiety or depression mood with physical stress of 59 participants (29 who complained of chronic headache and 30 who did not complain of headache) using a questionnaire on chronic headache symptoms, Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), and Heart Rate Variability (HRV). Methods: In this study, medical records of 59 participants (29 who complained of chronic headache and 30 who did not complain of headache) who completed the BAI, BDI, HRV, and Questionnaire for chronic headache symptoms were evaluated. All data were analyzed using SPSS (Statistical Package for the Social Sciences, Version 26.0). Descriptive Analysis, Mann-Whitney U test, Chi square test (Fisher's exact test), and Pearson correlation coefficient were used for data analysis. Results: 1. The chronic headache group had significantly lower SDNN, RMSSD, TP, LF, and HF values on HRV than the general control group. 2. As BAI and BDI scores of the chronic headache group increased, the overall HRV value tended to decrease, indicating a deep association. 3. There was a negative association between BDI and HRV values in the chronic headache group, although such association was not statistically significant. Conclusions: BDI can be negatively correlated with HRV (SDNN, RMSSD, TP, LF, HF) in chronic headache patients.

• Advances in Computational Design
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• 제8권1호
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• pp.13-36
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• 2023

The Puebla-Morelos Earthquake (Mw 7.1) occurred in Mexico in 2017 causing 44 buildings to collapse in Mexico City. This work evaluates the non-linear response of a 6-story reinforced concrete (RC) frame prototype model with masonry infill walls on upper floors. The prototype model was designed using provisions prescribed before 1985 and was subjected to seismic excitations recorded during the earthquakes of 1985 and 2017 in different places in Mexico City. The building response was assessed through a damage index (DI) that considers low-cycle fatigue of the steel reinforcement in columns of the first floor, where the steel was modeled including buckling as was observed in cases after the 2017 earthquake. Isocurves were generated with 72 seismic records in Mexico City representing the level of iso-demand on the structure. These isocurves were compared with the location of 16 collapsed (first-floor column failure) building cases consistent with the prototype model. The isocurves for a value greater than 1 demarcate the location where fatigue failure was expected, which is consistent with the location of 2 of the 16 cases studied. However, a slight increase in axial load (5%) or decrease in column cross-section (5%) had a significant detrimental effect on the cumulated damage, increasing the intensity of the isocurves and achieving congruence with 9 of the 16 cases, and having the other 7 cases less than 2 km away. Including column special detailing (tight stirrup spacing and confined concrete) was the variable with the greatest impact to control the cumulated damage, which was consistent with the absence of severe damage in buildings built in the 70s and 80s.

• 기록학연구
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• 제52호
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• pp.171-212
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• 2017

음악은 오랜 시간에 걸쳐 여러 환경 속에서 각각의 감정과 이야기를 담아 만들어지고 불려져 왔다. 사회 구성원으로부터 이야기를 담아 만들어지는 음악은 듣는 사람들이 자신의 경험과 감정에 비추어 주관적으로 해석하기도 하고, 한편으로 그 음악을 통하여 다른 사람들과 공감대를 느끼며 서로 소통하기도 하기 때문에 당대 사람들의 정서를 반영한다고 할 수 있다. 하지만 음악을 받아들이는 수용자의 입장과 음악을 만드는 창작자의 입장은 다를 수 있다. 본래 음악과 같은 예술작품에는 창작자의 의도가 작품의 탄생 배경이 되고, 그 작품이 가지는 주된 의미가 될 수 있다. 이에 비해 대중음악은 상업적이고 대중적인 주류의 음악 유통 시스템 아래서 자본에 의해 상업적으로 제작되기 때문에, 창작자의 의도가 자본의 영향으로부터 벗어날 수 없다. 반면 자본으로부터 '독립'해서 자기들의 음악을 추구하는 인디 음악은 대중음악과 반대로 창작자의 의도가 순수하게 온전히 담길 수 있다. 이런 인디 음악을 생산하고 활용하는 인디 밴드의 활동과 관련된 자료를 수집하고 분석해 봄으로써, 한국 인디 밴드 활동에 대한 기록이 당대 사회상에 갖는 의미와 가치에 대해 알아보고자 한다.

• 한국도서관정보학회지
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• 제39권4호
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• pp.397-420
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• 2008

이 연구는 최근 다문화도서관이나 도서관에서의 다문화서비스에 대한 관심이 증가함에 따라 현실적인 문제로 다가오고 있는 '다문화 장서의 목록 구축'에 대한 문제를 논의하고자 하는데 목적을 두고 있다. 특히 이 연구에서는 "(사)아시아공동체 부설 국제어린이도서관"에서 소장하고 있는 1만 여권의 다문화 장서에 대한 목록 구축 경험에 기초하여 향후 다문화 장서의 목록 구축에 적용할수 있는 체험적 방안을 도출하고자 하였다. 구체적으로, 이 연구에서는 (1) 그동안 다문화 장서의 목록 구축에 관한 국내외 도서관계의 기존 논의를 추적하고, (2) 현재 우리나라의 공공도서관과 대학도서관, 그리고 민간도서관에서 경험하고 있는 다문화 장서 목록 구축의 사례와 북미 도서관계의 사례를 비교하여 살펴본 다음, (3) 실제 목록 구축의 경험을 통해 향후 우리 도서관계에서 다문화 장서의 목록을 체계적으로 구축하기 위한 방안과 향후 과제에 대해 논의하였다.

• Journal of Animal Science and Technology
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• 제57권5호
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• pp.17.1-17.6
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• 2015

The present study investigated the nutritional and economic suitability of cashew reject meal (full fat and defatted) as replacement for groundnut cake (GNC) in the diets of laying chickens. A total of eighty four brown shavers at 25 weeks of age were randomly allotted into seven dietary treatments each containing 6 replicates of 2 birds each. The seven diets prepared included diet 1, a control with GNC at $220gkg^{-1}$ as main protein source in the diet. Diets 2, 3 and 4 consist of gradual replacement of GNC with defatted cashew reject meal (DCRM) at 50%, 75% and 100% on weight for weight basis respectively while diets 5, 6 and 7 consist of gradual inclusion of full fat cashew reject meal (FCRM) to replace 25%, 35% and 50% of GNC protein respectively. Each group was allotted a diet in a completely randomized design in a study that lasted eight weeks during which records of the chemical constituent of the test ingredients, performance characteristics, egg quality traits and economic indicators were measured. Results showed that the crude protein were 22.10 and 35.4% for FCRM and DCRM respectively. Gross energy of DCRM was 5035 kcal/kg compared to GNC, 4752 kcal/kg. Result of aflatoxin $B_1$ revealed moderate level between 10 and $17{\mu}g/Kg$ in DCRM and GNC samples respectively. Birds on control gained 10 g, while those on DCRM and FCRM gained about 35 g and 120 g respectively. Feed intake declined (P < 0.05) with increased level of FCRM. Hen day production was highest in birds fed DCRM, followed by control and lowest value (P < 0.05) was recorded for FCRM. No significant change (P > 0.05) was observed for egg weight and shell thickness. Fat deposition and cholesterol content increased (P > 0.05) with increasing level of FCRM. The cost of feed per kilogram decreased gradually with increased inclusion level of CRM. The prediction equation showed the relative worth of DCRM compared to GNC was 92.3% whereas the actual market price of GNC triples that of DCRM. It was recommended that GNC could be completely replaced by DCRM in layer's diets in regions where this by product is abundant. However, FCRM should be cautiously used in diets of laying chickens.

• Journal of Korean Neurosurgical Society
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• 제60권1호
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• pp.21-29
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• 2017

Objective : The purpose of this study was to analyze outcomes and identify prognostic factors in patients with cerebral metastases from non-small cell lung cancer (NSCLC) treated with gamma knife radiosurgery (GKS) particularly, focusing on associations of biomarkers and systemic treatments. Methods : We retrospectively reviewed the medical records of 134 patients who underwent GKS for brain metastases due to NSCLC between January 2002 and December 2012. Representative biomarkers including epidermal growth factor receptor (EGFR) mutation, K-ras mutation, and anaplastic lymphoma kinase (ALK) mutation status were investigated. Results : The median overall survival after GKS was 22.0 months (95% confidence interval [CI], 8.8-35.1 months). During follow-up, 63 patients underwent salvage treatment after GKS. The median salvage treatment-free survival was 7.9 months (95% CI, 5.2-10.6 months). Multivariate analysis revealed that lower recursive partition analysis (RPA) class, small number of brain lesions, EGFR mutation (+), and ALK mutation (+) were independent positive prognostic factors associated with longer overall survival. Patients who received target agents 30 days after GKS experienced significant improvements in overall survival and salvage treatment-free survival than patients who never received target agents and patients who received target agents before GKS or within 30 days (median overall survival: 5.0 months vs. 18.2 months, and 48.0 months with p-value=0.026; median salvage treatment-free survival: 4.3 months vs. 6.1 months and 16.6 months with p-value=0.006, respectively). To assess the influence of target agents on the pattern of progression, cases that showed local recurrence and new lesion formation were analyzed according to target agents, but no significant effects were identified. Conclusion : The prognosis of patients with brain metastases of NSCLC after GKS significantly differed according to specific biomarkers (EGFR and ALK mutations). Our results show that target agents combined with GKS was related to significantly longer overall survival, and salvage treatment-free survival. However, target agents were not specifically associated with improved local control of the lesion treated by GKS either development of new lesions. Therefore, it seems that currently popular target agents do not affect brain lesions themselves, and can prolong survival by controlling systemic disease status.

• Asian-Australasian Journal of Animal Sciences
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• 제32권7호
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• pp.913-921
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• 2019

Objective: The objectives of this study were to compare identified informative regions through two genome-wide association study (GWAS) approaches and determine the accuracy and bias of the direct genomic value (DGV) for milk production traits in Korean Holstein cattle, using two genomic prediction approaches: single-step genomic best linear unbiased prediction (ss-GBLUP) and Bayesian Bayes-B. Methods: Records on production traits such as adjusted 305-day milk (MY305), fat (FY305), and protein (PY305) yields were collected from 265,271 first parity cows. After quality control, 50,765 single-nucleotide polymorphic genotypes were available for analysis. In GWAS for ss-GBLUP (ssGWAS) and Bayes-B (BayesGWAS), the proportion of genetic variance for each 1-Mb genomic window was calculated and used to identify informative genomic regions. Accuracy of the DGV was estimated by a five-fold cross-validation with random clustering. As a measure of accuracy for DGV, we also assessed the correlation between DGV and deregressed-estimated breeding value (DEBV). The bias of DGV for each method was obtained by determining regression coefficients. Results: A total of nine and five significant windows (1 Mb) were identified for MY305 using ssGWAS and BayesGWAS, respectively. Using ssGWAS and BayesGWAS, we also detected multiple significant regions for FY305 (12 and 7) and PY305 (14 and 2), respectively. Both single-step DGV and Bayes DGV also showed somewhat moderate accuracy ranges for MY305 (0.32 to 0.34), FY305 (0.37 to 0.39), and PY305 (0.35 to 0.36) traits, respectively. The mean biases of DGVs determined using the single-step and Bayesian methods were $1.50{\pm}0.21$ and $1.18{\pm}0.26$ for MY305, $1.75{\pm}0.33$ and $1.14{\pm}0.20$ for FY305, and $1.59{\pm}0.20$ and $1.14{\pm}0.15$ for PY305, respectively. Conclusion: From the bias perspective, we believe that genomic selection based on the application of Bayesian approaches would be more suitable than application of ss-GBLUP in Korean Holstein populations.