• 제목/요약/키워드: control effect

검색결과 32,056건 처리시간 0.058초

길경해독탕이 항암 및 항전이 효과에 미치는 영향 (The Effects of Gilgyunghaedok-tang on Antitumor and Antimetastatic Activity)

  • 왕중권;정희재;이형구;정승기
    • 대한한의학회지
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    • 제23권2호
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    • pp.211-224
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    • 2002
  • Background and Objective : In order to investigate the effects of Gilgyunglwedok-tang (GRT) on antitumor activity and antimetastatic activity, studies were done experimentally. Materials and Methods : Experimental studies were perfonned for the cytotoxic effect on BALB/c mouse lung fibroblast cells, the proliferating effect of splenic lymphocyte, the expression of CD3e/CD4, CD3e/CD8, and B220 in peripheral blood mononuclear cells (PBMCs), the cytotoxic effect on A549, SK-OV-3, SK-MEL-2, MCF-7 cells, the inhibitory effect on the activity of DNA topoisomerase I, the T/C% in ICR mice bearing S-180, the inhibitory effect of Cell adhesive of A549 Cells and SK-OY-3 Cells to complex extracellular matrix, the inhibitory effect on lung colonies, the change of lung tissue, the antiangiogenic activity, and the effect on MMP-2 and MMP-9 gene expression in the RT1080 cell line. Results and Conclusion : The results were obtained as follows : 1. In the cytotoxic effect on BALB/C mouse lung fibroblast Cell, GHT didn't show the significant cytotoxic effect on BALB/C mouse lung fibroblast cell compared to the control group. 2. In thymidine uptake assay, GHT showed the significant proliferating effect of splenic lymphocyte in proportion to the concentration. 3. In the expression of CD3e/CD4, CD3e/CD8, and B220 in peripheral blood mononuclea cells (PBMCs) of mice, GRT had no significant change to the normal group in CD4. However, GRT showed an increase to the normal group in CD8 and GHT in the only $1\mu\textrm{g}/ml$ category showed an increase to the normal group in B220. 4. In the cytotoxic effect of GRT on A549, SK-OY-3, SK-MEL-2 and MCF-7 cells, there was no significant cytotoxic effect compared to the control group. 5. In the inhibitory effect on the activity of DNA topoisomerase I, GHT in the $10\mu\textrm{g}/ml$ category showed the inhibitory effect on the activity of DNA topoisomerase I in proportion to the concentration. 6. In the T/C% in ICRmice bearing S-180, GHTtreated group showed 123.7% of T/C% compared to the control group. 7. In the inhibitory effect of cell adhesive of A549 Cells and SK-OV-3 Cells to complex extracellular matrix, GRT in the only $100\mu\textrm{g}/ml$ category showed the significant inhibitory effect compared to the control group. 8. In the inhibitory effect on lung colonies, GHT showed the significant inhibitory effect on lung colonies compared to the control group. 9. In the change of lung tissue, GHT showed a significant decrease of lung cancer growth, interalveolar fibrosis and hyaline material compared to the control group. In the development of lymphocyte around lung cancer cells and lung parenchymal, GHT showed the significant inducement efficacy compared to the control group. 10. In CAM assay, the antiangiogenic activity of GHT showed 30%. 11. In the effect on MMP-2 and MMP-9 gene expression in the RT1080 cell line, GHT had no significant inhibitory effect on MMP-2 and MMP-9 gene expression compared to the control group. According to the above results, it could be suggested that GHT has an antitumor activity and antimetastatic activity.

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광고모델과의 사회적 비교과정에서 외모통제력 지각이 갖는 조정효과 (The Moderating Effect of Perceived Control over Appearance in the Social Comparison Process with Advertisement Models)

  • 이윤정
    • 한국의류학회지
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    • 제30권4호
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    • pp.633-643
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    • 2006
  • When women are exposed to images of other attractive women such as media models, it is known that many go through a social comparison process and a contrast effect occurs which results in unfavorable perception and attitudes toward the self. This paper suggests women's perception of control over their appearance as one of the factors that may moderate the contrast effect of a social comparison with attractive media models. An experiment with 211 women was conducted to examine the differential effect of viewing attractive models versus non-human images on the responses of women with high/low perceived control over appearance. A two(Stimuli Type: attractive-model image vs. non-human image) by two(Perceived Control over Appearance: High vs. Low) MANCOVA model was tested with physical appearance anxiety, self-esteem, and body satisfaction as dependent variables and appearance orientation, body mass index, age, years of schooling, ethnicity, and marital status as covariates. A significant Perceived Control main effect on Physical Appearance Anxiety and Self-Esteem and a significant Stimuli Type by Perceived Control interaction effect on Physical Appearance Anxiety and Self-Esteem were found. Those who perceived high control over their appearance were more likely to have higher self-esteem and lower appearance anxiety. However, among those who saw attractive model's images, women perceived low appearance control showed less anxiety and higher body satisfaction than those perceived high appearance control.

ATMD가 설치된 두 인접빌딩간 강성연결방식을 통한 내진성능 개선 (Seismic Response Enhancement through Stiffness Connection of Two Adjacent Buildings equipped with ATMD)

  • 박관순;옥승용
    • 한국안전학회지
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    • 제32권5호
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    • pp.47-53
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    • 2017
  • In this study, we propose a new control system that effectively utilizes the interaction effect of control force through the connection of stiffness member for seismic performance enhancement of two adjacent structures equipped with active tuned mass damper (ATMD). The efficiency of the proposed control system is verified by comparing with the existing independent control system through the numerical simulations of the 10th- and 12th-story buildings. From the numerical results, it is confirmed that the proposed method can show similar or better control performance even with more economical control capacity than the existing independent control system. Another advantage is that the existing system does not exhibit the adaptive control performance in emergency of failure of one control device, whereas the proposed system can achieve successful adaptive control performance by economically and efficiently utilizing the interacting control effect through the connection member.

중앙냉난방시스템의 EMS 복합제어 효과 분석에 관한 시뮬레이션 연구 (A Simulation Study on Effect Analysis of EMS Combined Control of Central Cooling and Heating System )

  • 송재엽;안병천
    • 한국지열·수열에너지학회논문집
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    • 제18권4호
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    • pp.33-44
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    • 2022
  • In this study, we analyze the existing heating and cooling operation method for an office-type complex building with a central heating and cooling system, and examine the effects of applying various EMS that can be applied according to the load size to save energy in the building. For this purpose, simulation analysis was performed. As a control method, reset control of chilled water, hot water, cooling water and supply air temperatures, optimal start/stop of heat source, and number of heat source control were applied according to the load size, and energy consumption was analyzed accordingly. In addition, when all of these control methods were applied, the overlapping energy saving effect was finally confirmed. As a result, it was possible to confirm the energy saving effect when EMS for reset control and heat source control were applied compared to the existing control method of the heating and cooling system, and the effect for the case of using all these control methods in combination was also confirmed.

리니어 홀-이펙트 센서를 이용한 교류 서보 모터의 위치제어 (The position control of an AC servo motor using linear hall-effect sensors)

  • 박희성;장성수;오성업;성세진
    • 한국조명전기설비학회:학술대회논문집
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    • 한국조명전기설비학회 2003년도 학술대회논문집
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    • pp.315-317
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    • 2003
  • This paper deals with the position control of an AC servo motor using linear hall-effect sensors. The price of these is very low, but it is possible to make position control of motor similar to a control using an encoder. This paper introduces the design of motor using linear hall-effect sensors and shows the results of control.

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중학생의 식생활 태도가 심리적 성취 및 자아관리에 미치는 영향 (The Effects of Eating Attitudes on Psychological Achievement and Self Control in Middle School Students)

  • 오성천
    • 한국식품영양학회지
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    • 제25권3호
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    • pp.483-489
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    • 2012
  • In this study, a survey was carried out on 208 students at middle schools in Gyeonggi-do through May 1 to July 20, 2011, with the purpose of figuring out how eating attitudes of middle school students affect their psychological achievement and self control. The results were as follows. First, the effect of eating attitudes on the psychological achievement of middle school students demonstrated that regular dietary life, dietary life and health had a statistically significant positive effect on psychological achievement. Second, the effect of eating attitudes on self control in middle school students showed that balanced dietary life, dietary life and health had a statistically significant positive effect on self control. The above findings confirmed that regular and healthy dietary life connected directly with health, which was a factor that makes them think positively about psychological achievement. Besides, for eating self control, as balanced dietary life in eating attitudes was important. And as this had a positive effect on their self control, could improve their eating attitudes. Consequently, the regular eating attitudes and balanced dietary life in eating attitudes of middle school students can make their psychological achievement and eating self control for the nutrition and health care.

고객특성이 전환장벽, 전환의도와 재방문의사에 미치는 영향 - 여행사.항공사간 비교분석을 중심으로 - (Impact of Switchover Barrier, Switchover Intention and Willingness to Revisit on Customer's Characteristics - Comparison between Travel Agency and Airlines -)

  • 정웅용;문혜영
    • 한국콘텐츠학회논문지
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    • 제8권9호
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    • pp.259-273
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    • 2008
  • 경제의 발전과 더불어 산업사회가 고도화 되면서 국민소득의 증가, 여가시간의 증가, 여성의 취업 증가 등의 변화에 따라 국민의 생활수요도 다양해지고 있다. 이러한 수요의 변화에 따라 서비스 산업은 여러 형태로 발전하면서 오늘날 현대 경제는 서비스 경제 또는 서비스 사회라고도 불리어 지고 있다. 이는 서비스 산업이 경제 전체에서 차지하는 비중이 확대되고 서비스 산업의 범위가 넓어지고 있고 현대사회에서 서비스 산업의 중요성이 크게 부각되고 있기 때문이다. 이러한 서비스 산업의 경우 최근 경쟁이 치열해지고 브랜드에 대한 충성도가 감소함에 따라 신규고객 유치와 시장점유율 확대 등의 공격적 마케팅전략 보다는 기존고객 유지의 방어적 마케팅 전략의 중요성이 커지고 있다. 특히 여행사와 항공사의 경우 많은 경쟁과 성수기, 비수기의 수요 양극화 현상 등으로 인하여 서비스전환의 용이성이 증가함에 따라 기존 고객을 유지하고 전환을 억제하는 것이 더욱 중요시되고 있는 실정이다. 이에 본 연구는 고객특성에 따른 전환장벽과 전환의도 그리고 재방문 의사의 관계에 대하여 연구하여 업계에 도움이 되는 시사점을 찾고자 하였다.

The Moderating Effect of Internal Control on Performance of Cross-Border M&A under the Uncertainty of Economic Policy: Evidence from China

  • Huang, Xiao-Lin;Chen, Guan-Ting;Lee, Eun-Hye
    • Journal of Korea Trade
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    • 제23권7호
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    • pp.128-146
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    • 2019
  • Purpose - The purpose of this paper is to investigate the relationship between internal control, economic policy uncertainty, and performance of cross-border merger and acquisition (M&A) based on the panel data of Chinese listed firms. The authors expected that internal control has a positive moderating effect on the performance of cross-border M&A and that it mainly occurs during periods when economic policies are relatively stable. In addition, the authors tried to find out the mechanism of internal control affecting cross-border M&A and the corporate performance. Design/methodology - The authors tested the hypotheses by a multivariate regression model based on the panel data of Chinese listed firms from 2009 to 2017. The dependent variable is the change value of business performance (DROA_1,2,3) and the explanatory variables are cross-border M&A (MA), China's uncertainty of economic policy (EPU), and internal control level (IC) respectively. Findings - The authors find that internal control has a positive moderating effect on the relationship between cross-border M&A and corporate performance. Further, the authors find that the moderating effect is more significant in state-owned enterprises and that it mainly occurs during periods when economic policies are relatively stable. Originality/value - This paper is the leading study that tries to analyze empirically the relationship between internal control, economic policy uncertainty, and performance of cross-border M&A. It provides a new avenue through which internal control might reasonably mitigate the risks of cross-border M&A and correspondingly improve the performance of cross-border M&A. It also confirms the moderating effect of internal control on the performance of cross-border M&A under the uncertainty of economic policy.

콴다효과를 응용한 플랩이 달린 고양력 날개장치에 대한 실험적 연구 (An Experimental Study of Coanda Effect on the Flapped Control Surfaces)

  • 안해성;김효철
    • 대한조선학회논문집
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    • 제40권5호
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    • pp.10-16
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    • 2003
  • To investigate the jet effect on circulation control, a segment of model was prepared and inserted horizontally across the test section of the cavitation tunnel. The hydrodynamic forces acting on the model were measured under the 2 dimensional flow behavior. Circulation flow control requires higher flow rate of water jet than boundary layer control does. Jet injection is effective in increasing lift coefficient and the increments reach to 160% in a certain combination of parameters such as an angle of attack, jet flow rate and flap angle. The blown water jet not only reduces form drag but also thrust effect, which is sometimes greater than the form drag in specific conditions.

프린징효과를 고려한 미세각도 제어용 3상 가변형 셀프베어링 스텝모터의 해석 및 제어 (Analysis and Control of a 3-Phase VR Type Self-Bearing Step Motor for Small Angle Control Considered the fringing Effect)

  • 김대곤
    • 한국정밀공학회지
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    • 제18권10호
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    • pp.93-100
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    • 2001
  • The analysis and control of a new type unsymmetrical slotted self-bearing step motor for small angle control is presented. The motor actuator is used for both motor and bearing functionality without any additional coil windings or electromagnets for bearing functionality. A circular-arc, straight-line permeance model for the fringing effect is presented. An unsymmetrical slotted self-bearing step motor layout and control algorithm are described. A new control current generation method using the electromagnets layout geometry, which needs no additional current for bearing functionality, is proposed. As the result of this analysis the fringing effect largely influences on the system characteristics. especially in torque. Even if the bearing functionality is added into the motor functionality, it is shown that the magnitude of torque is not changed.

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