• Title/Summary/Keyword: contour analysis

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Comparative Molecular Field Analyses on the Fungicidal Activities of N-phenylthionocarbamate Derivatives based on Different Alignment Approaches (상이한 정렬에 따른 N-phenylthionocarbamate 유도체들의 살균활성에 관한 비교 분자장 분석)

  • Sung, Nack-Do;Soung, Min-Gyu;You, Jae-Won;Jang, Seok-Chan
    • The Korean Journal of Pesticide Science
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    • v.10 no.3
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    • pp.157-164
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    • 2006
  • Three dimensional quantitative structure-activity relationships (3D-QSARs) for the fungicidal activities against Rhizoctonia solani (RS) and Phytophthora capsici (PC) by N-phenyl substituents(X) of N-phenylthionocarbamate derivatives were studied quantitatively using comparative molecular field analysis (CoMFA) methodology based on different alignment approaches. Statistical quality of CoMFA models with field fit alignment were slightly higher than that of atom based fit alignment. The optimized CoMFA models (RS: RF2 & PC: PF2) were derived from field fit alignment and combination of CoMFA fields. And the statistical results of the two models showed the best predictability of the fungicidal activities based on the cross-validated value $q^2$ ($r^2_{cv.}$ =RS: 0.557 & PC: 0.676) and non-cross-validated value ($r^2_{ncv.}$ =RS: 0.954 & PC: 0.968), respectively. The selective fungicidal activities between two fungi were dependence upon the electrostatic field of substrate molecule. Therefore, the fungicidal activities from CoMFA contour maps showed that the fungicidal activity will be able to increased according to the modification of X-substituents on the substrate molecules.

Minimum Structural Requirements of R-phenoxy Substituents for Herbicidal Evaluation of O-(2-phenoxy)ethyl-N-aralkylcarbamate Analogues against Phytoene Desaturase (Phytoene Desaturase에 대한 O-(2-Phenoxy)ethyl-N-aralkylcarbamates 유도체의 제초성 평가를 위한 R-phenoxy 치환기들의 구조적인 요건)

  • Choi, Won-Seok;Lee, Jae-Whang;Hwang, Seung-Woo;Sung, Nack-Do
    • The Korean Journal of Pesticide Science
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    • v.14 no.1
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    • pp.72-77
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    • 2010
  • The minimum structural requirements of R-phenoxy substituents for herbicidal evaluation of O-(2-(R)-phenoxy)-ethyl-N-aralkylcarbamate (1-15) analogues against phytoene desaturase (PDS) based on the three dimensional quantitative structure-activity relationships (3D-QSARs: CoMFA and CoMSIA) were studied quantitatively. The correlativity and predictability ($r^2_{cv.}=0.753$ and $r^2_{ncv.}=0.964$) of the CoMFA 1 model were higher than those of the rest models. The PDS inhibitory activities from the optimized CoMFA 1 model were depend upon the steric field (44.0%), electrostatic field (36.3%), and hydrophobic field (19.6%) of O-(2-(R)-phenoxy)ethyl-Naralkylcarbamate analogues. From the CoMFA contour maps on the structure of the most active compound (5), if it has the steric favor at meta-, para-position on the phenoxy ring, the negative charge favor in meta-position and positive charge favor in the outside part of para-position, the inhibitory activity will be predicted to increase. Also, if ortho-, para-position, and outside of phenoxy ring are hydrophilic favor, and meta-position is hydrophobic favor, it is predicted that the inhibitory activity against PDS will be able to increase.

Analysis of Agricultural Climatology in Cheju Island I. Distribution of Daily Minimum Temperature in Winter Season Estimated from a Topoclimatological Method (제주도의 농업기후 분석 I. 지형기후 추정법과 동계 일최저기온 분포)

  • 윤진일;유근배;이민영;정귀원
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.34 no.3
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    • pp.261-269
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    • 1989
  • Agricultural activities in Chejudo require more specialized weather services in this region. The meteorological information available from the Korea Meteorological Service (KMS) is limited in its areal coverage because the KMS stations are located along the narrow band of coastal area. topoclimatological technique which makes use of empirical relationships between the topography and the weather can be applied to produce reasonable estimates of the climatic variables such as air temperature and precipitation over remote land area where routine observations are rare. Presentation of these estimates in a from of fine-mesh grid map can also be helpful to upgrade the quality of weather services in this region. Altitude values of the 250 m grid points were read from a 1: 25000 topographic map and the mean altitude, the mean slope, and the aspect of the slope were determined for each 1 km$^2$ land area from these altitude data. Daily minimum air temperature data were collected from 18 points in Chejudo during the winter period from November 1987 to February 1988. The data were grouped into 3 sets based on synoptic pressure pattern. Departures from the KMS observations were regressed to the topographical variables to delineate empirical relationships between the local minimum temperature under specific pressure patterns and the site topography. The selected regression equations were used to calculate the daily minimum temperature for each 1 km$^2$ land area under the specific pressure patterns. The outputs were presented in a fine-mesh grid map with a 6-level contour capability.

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Spatial Distribution of Macropore Flow Percentage and Macroporosities in the Gwangneung Forest Catchment (광릉 산림 소유역에서의 대공극흐름율과 유효대공극부피분율의 공간 분포)

  • Gwak, Yong-Seok;Kim, Su-Jin;Kim, Joon;Lim, Jong-Hwan;Kim, Sang-Hyun
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.9 no.4
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    • pp.234-246
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    • 2007
  • The role of macropore in the hydrological processes is important at the hillslope scale. Developments and distribution of macropores have not been investigated in conjunction with the characteristics of the hillslope such as topography, soil property, and soil moisture. In this study, macropore properties, such as macropore flow and saturation hydraulic conductivity were measured at a hillslope located in Gwangneung Research Forest, Pochun-gun, Gyeonggi-do, South Korea. An intensive field survey provided a refined Digital Elevation Model (DEM) for surface and subsurface topography. Spatial distributions of upslope area and topographic index were obtained through the digital terrain analysis. The total number of monitoring points was 22, and the selected points were distributed along the transect of the digital contour map. Vertical fluxes through macropores were measured using a tension infiltrometer at the depth of 0.1 m from the surface. Spatial and temporal distributions of soil moisture were obtained using an on-line measurement system, TRASE, installed in the study area. Soil moisture for the aforementioned points was measured at 0.1 and 0.3m depths below the surface. The results from tension infiltrometer experiments present that the macropore flows ranged between 21 and 94%, and the measured macroporosities varied from 1.4 to 47%. Macropore flows and macroporosities tended to increase as the measurement location moved to downslope. The ability for water conduction through macropores becomes increasingly developed as the location approaches the outlet of the hillslope.

ALVEOLAR BONE LOSS AFTER THE EARLY LOSS OF UPPER CENTRAL INCISOR IN GROWING CHILDREN (성장기 어린이에서 상악 중절치 조기 상실 후 치조골 소실)

  • Na, Hye-Jin;Song, Je-Seon;Lee, Jae-Ho;Choi, Hyung-Jun;Kim, Seong-Oh;Son, Heung-Kyu;Choi, Byung-Jai
    • Journal of the korean academy of Pediatric Dentistry
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    • v.39 no.1
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    • pp.51-57
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    • 2012
  • The anterior maxillary incisor is the most traumatized region in the mouth and trauma is frequent between the ages of 8-10. Traumatic loss of teeth, can lead to many complications in children. Thus, as possible to keep traumatic teeth, but if you need extractions There may be. Complications occur and early tooth loss is frequent. Complications of early loss of central incisors are esthetic compromise, loss of vertical and horizontal width, height, contour of alveolar bone, tilting of adjacent teeth, arch length loss. Alveolar bone loss may affect normal function and stability, and results in esthetic problem for future prosthesis restoration. The 9-year-old girl and 6-year-old boy got early loss of upper central incisor. The amount of alveolar bone resorption was measured using cone beam computed tomograph and cast analysis.

Field Tracer Experiments under Severe Wether Conditions for the Validation of the Dispersion of Radioactive Materials (방사능 확산 검증을 위한 악기상 조건에서의 추적자 야외확산 실증실험)

  • Han, Moon Hee;Kim, Eun Han;Jeong, Hyo Joon;Jeong, Hae Sun;Park, Mi Sun;Hwang, Won Tae
    • Journal of Radiation Protection and Research
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    • v.38 no.4
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    • pp.208-213
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    • 2013
  • The suitability of the site criteria is a basic requirement for securing safety of nuclear power plants. The suitability should be confirmed through the estimation of environmental radiation effects at the exclusion area boundary under the severe weather conditions. In this study, field tracer experiments over short range of 1 km radius under severe weather conditions were conducted at flat area in Daejeon. Severe weather conditions are represented with stable atmospheric condition and low wind speed. In general, the condition is appeared at clean night time with weak wind. The analysis of the measured distribution of the released tracer gas shows two big differences between the results of the past experiments conducted under the favorable weather conditions. One is the difficulty of finding the typical distribution of the released tracer gas with peak concentration in the downwind direction. The other one is the appearance of the contour of the concentration of tracer gas at several hundred meters even though the gas released at 10 m height over the ground.

An Error Analysis of the 3D Automatic Face Recognition Apparatus (3D-AFRA) Hardware (3차원 안면자동분석 사상체질진단기의 Hardware 오차분석)

  • Kwak, Chang-Kyu;Seok, Jae-Hwa;Song, Jung-Hoon;Kim, Hyun-Jin;Hwang, Min-Woo;Yoo, Jung-Hee;Kho, Byung-Hee;Kim, Jong-Won;Lee, Eui-Ju
    • Journal of Sasang Constitutional Medicine
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    • v.19 no.2
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    • pp.22-29
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    • 2007
  • 1. Objectives Sasang Contitutional Medicine, a part of the traditional Korean medical lore, treats illness through a constitutional typing system that categorizespeople into four constitutional types. A few of the important criteria for differentiating the constitutional types are external appearances, inner state of mind, and pathological patterns. We had been developing a 3D Automatic Face Recognition Apparatus (3D-AFRA) in order to evaluate the external appearances with more objectivity. This apparatus provides a 3D image and numerical data on facial configuration, and this study aims to evaluate the mechanical accuracy of the 3D-AFRA hardware. 2. Methods Several objects of different shapes (cube, cylinder, cone, pyramid) were each scanned 10 times using the 3D Automatic Face Recognition Apparatus (3D-AFRA). The results were then compared and analyzed with data retrieved through a laser scanner known for its high accuracy. The error rates were analyzed for each grid point of facial contour scanned with Rapidform2006 (Rapidform2006 is a 3D scanning software that collects grid point data for contours of various products and products and product parts through 3D scanners and other 3D measuring devices; the grid point data thusly acquired is then used to reconstruct highly precise polygon and curvature models). 3. Results and Conclusions The average error rate was 0.22mm for the cube, 0.22mm for the cylinder, 0.125mm for the cone, and 0.172mm for the pyramid. The visual data comparing error rates for measurement figures retrieved with Rapidform2006 is shown in $Fig.3{\sim}Fig.6$. Blue tendency indicates smaller error rates, while red indicates greater error rates The protruding corners of the cube display red, indicating greater error rates. The cylinder shows greater error rates on the edges. The pyramid displays greater error rates on the base surface and around the vertex. The cone also shows greater error around the protruding edge.

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Comparative molecular field analyses(CoMFA) on the growth inhibition activity of N-phenyl-3,4,5,6-tetrahydrophthalimide and N-phenyl-3,4-dimethylmaleimide Derivatives (N-치환 phenyl-3,4,5,6-tetrahydrophthalimide와 N-치환 phenyl-3,4-dimethylmaleimide 유도체의 생장 저해활성에 관한 l 분자장 분석 (CoMFA))

  • Sung, Nack-Do;Ock, Hwan-Suk;Song, Jong-Hwan;Lee, Yong-Gu
    • The Korean Journal of Pesticide Science
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    • v.7 no.2
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    • pp.75-82
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    • 2003
  • We discuss that the growth inhibition activities against root and shoot of rice plant (Oryza sativa L.) and barnyard grass (Echinochloa crus-galli) by N-phenyl-3,4,5,6-tetrahydrophthalimide (A) and N-phenyl-3,4-dimethylmaleimide (B) derivatives with changing substituents can be explained and predicted using comparative molecular field analyses (CoMPA) method. And the results show that the cross-validation value, $q^2$ at three components and Pearson correlation coefficient, $r^2$ were rice plant: shoot; $r^2=0.987$, $q^2=0.387$ & root; $r^2=0.923$, $q^2=0.307$ and barnyard grass: shoot; $r^2=0.902$, $q^2=0.535$ & root; $r^2=0.900$, $q^2=0.450$, respectively. In addition, The activities of unknown compounds were predicted by CoMFA method. From the contour map of (A) derivatives, the selective factors to remove barnyard grass takes positive charge on the benzylic carbon atom (C27), negative charged carbon atom (C29) of meta position and steric bulky groups on the cyclic imino ring (C7-C8).

Development of Automatized Quantitative Analysis Method in CT Images Evaluation using AAPM Phantom (AAPM Phantom을 이용한 CT 영상 평가 시 자동화된 정량적 분석 방법 개발)

  • Noh, Sung Sun;Um, Hyo Sik;Kim, Ho Chul
    • Journal of the Institute of Electronics and Information Engineers
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    • v.51 no.12
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    • pp.163-173
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    • 2014
  • When evaluating the spatial resolution images and evaluation of low contrast resolution using CT standard phantom, and might present a automated quantitative evaluation method for minimizing errors by subjective judgment of the evaluator be, and try to evaluate the usefulness. 120kVp and 250mAs, 10mm collimation, SFOV(scan field of view) of 25cm or more than, exposure conditions DFOV(display field of view) of 25cm, and were evaluated the 24 passing images and 20 failing images taken using a standard reconstruction algorithm by using the Nuclear Associates, Inc. AAPM CT Performance Phantom(Model 76-410). Quantitative evaluation of low contrast resolution and spatial resolution was using an evaluation program that was self-developed using the company Mathwork Matlab(Ver. 7.6. (R2008a)) software. In this study, the results were evaluated using the evaluation program that was self-developed in the evaluation of images using CT standard phantom, it was possible to evaluate an objective numerical qualitative evaluation item. First, if the contrast resolution, if EI is 0.50, 0.51, 0.52, 0.53, as a result of evaluating quantitatively the results were evaluated qualitatively match. Second, if CNR is -0.0018~-0.0010, as a result of evaluating quantitatively the results were evaluated qualitatively match. Third, if the spatial resolution, as a result of using a image segmentation technique, and automatically extract the contour boundary of the hole, as a result of evaluating quantitatively the results were evaluated qualitatively match.

Development of Tomographic SASW Method to Evaluate Two-Dimensional Variability of Shear Stiffness (지반 및 구조물의 이차원적 전단강성 평가를 위한 토모그래픽 SASW 기법의 개발)

  • 조성호
    • Journal of the Korean Geotechnical Society
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    • v.15 no.2
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    • pp.29-42
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    • 1999
  • The SASW (Spectral-Analysis-of-Surface-Waves) method, which evaluates the stiffness structure of the subsurface and structures nonintrusively and nondestructively, has been successfully used in the civil engineering applications. However, the SASW method assumes that the subsurface or structures consist of horizontal multi-layers, so that the method has some difficulty in continuously evaluating the integrity of a tunnel lining and a pavement system. This difficulty prevents the SASW method from being used to generate a tomographic image of stiffness for the subsurface or structures. Recently, the GPR technique which has the advantage of continuously evaluating integrity of the subsurface and structures has been popular. This advantage of GPR technique initiated the efforts to make the SASW method, which is superior to GPR and other nondestructive testing methods due to its capability of evaluating stiffness and modulus, be able to do continuous evaluation of stiffness structure, and the efforts finally lead to the development of \ulcornerTomographic SASW Technique.\ulcorner Tomographic SASW technique is a variation of the SASW method, and can generate a tomographic image of stiffness structure along the measurement line. The tomographic SASW technique was applied to the investigation of lateral variability of a sand box placed by the raining method for the purpose of verifying its effectiveness. Tomographic SASW measurements on the sand box revealed that the investigated sand box has different shear stiffness along the measurement line, which gave a clue of how to make a better raining device.

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