• Title/Summary/Keyword: contact dermatitis

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Analysis of Case Studies on Contact Dermatitis with Korean Medicine Treatments (접촉 피부염의 한방 치료 증례연구 분석)

  • Kim, Hye-Gyeong;Kyung, Da-Hyun;Kim, Min-Kyung;Huh, Hyo-Seung;Lim, Seung-Hwan
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.33 no.4
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    • pp.100-113
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    • 2020
  • Objectives : The purpose of this study is to analyze the trend of Korean medical treatments on contact dermatitis. Methods : Based on NDSL, OASIS, RISS, KTKP, KISS, KCI with the keyword 'Contact Dermatitis', published in 2001-2020.06.10., total 12 studies have been found and analyzed. Results : Out of 1,046 articles searched, 12 papers were selected. All of those were case-study. Herb medicine, acupuncture, pharmacopuncture, externals, other treatments were used as treatment for contact dermatitis. All of research which selected have reported that the Korean medical treatment was effective. Conclusions : According to the results, Korean medical treatments can be effective treatment for contact dermatitis. Further clinical studies are expected using evaluation methods to analyze the results and to establish high level of evidence.

Effect of DHU001, a Polyherbal Formula, on Dinitrofluorobenzene-induced Contact Dermatitis (Type I allergy)

  • Lee, Hyeung-Sik;Lee, Byung-Chang;Ku, Sae-Kwang
    • Toxicological Research
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    • v.26 no.2
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    • pp.123-130
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    • 2010
  • The effect of DHU001, a mixed herbal formula consisted of 7 types aqueous extracts for various respiratory disorders were evaluated on 2,4-dinitrofluorobenzene (DNFB)-induced contact dermatitis, type I allergic model. Contact dermatitis was induced by sensitization with dinitrophenyl-derivatized ovalbumin (DNP-OVA) and DNFB challenge as antigen. Two different dosages of DHU001 (300 and 150 mg/kg) were orally administered to DNP-OVA sensitization mice once a day for 7 days with reference material, dexamethasone (15 mg/kg, intraperitoneal treatment). End of 7 days oral administration of DHU001 extracts or intraperitoneal treatment of dexamethasone, the changes on the edematous changes and scratching behavior were measured. Immediate after DNFB challenge on ear or paw of DNP-OVA sensitized mice, increases of ear and paw thicknesses and weights were detected with anterior ear skin (dermis to epidermis) thickness and paw scratching behavior increases. However, these contact dermatitis signs induced by DNFB treatment were reduced by treatment of the both different dosages of DHU001 and dexamethasone, respectively. The results obtained in this study suggest that oral treatment of DHU001 extracts also has relatively favorable effects on contact dermatitis.

Effects of Chogam-Tang on Rat Skin Induced the Allergic Contact Dermatitis (백서(白鼠)에 유도된 알러지성 피부염에 대한 초감탕(椒甘湯)의 효과)

  • Yoon, Hui-Sung;Park, Owe-Suk;Kim, Hee-Jeong;Kim, Keoo-Seok;Kim, Yoon-Bum
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.18 no.3
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    • pp.44-54
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    • 2005
  • Background and Objectives: Allergic contact dermatitis is a common environmental health issue and seriously affect the patient's quality of life. The more our environment industrialized, the number of material that could cause the allergic contact dermatitis has been increased, consequently the prevalence of allergic contact dermatitis has been increased. In oriental medicine, clinically Chogam-Tang has been used fur the treatment of allergic dermatitis, eczema, atopic dermatitis etc. The objective of this study is to investigate the effects of Chogam-Tang on allergic contact dermatitis Meterial and Methods: Fifteen Sprague-Dawley rats were divided into three groups: normal, control, experimental group. Control and experimental group were induced allergic contact dermatitis, by DNCB. Experimental group was orally administered the Chogam-Tang. Each group was observed after 24, 48 and 72 hours. Contact hypersensitivity assay, melanin-erythema measurement, pH measurement skin moisture measurement and biopsy were performed. Results: 1. In contact hypersensitivity assay, experimental group showed decreased ear swelling compared with control group at 48hours. 2. ln melanin measurement there was no difference in three groups. 3. In erythema measurement experimental group showed reduction at 48. 72 hours. 4. In pH measurement, experimental group and control group showed increase in pH but there was no statistical significance. 5. In skin moisture measurement, experimental group showed higher skin moisture level than control group at 24 hours and showed lower skin moisture level at 72 hours, but there was no statistical significance. 6. In biopsy, experimental group showed decrement of Iymphocyte as time goes by, and regeneration of keratin layer was increased compared with normal group. Conclusions: Chogam-Tang shows anti-inflammatory effect in biopsy, improves hydration levels of skin, decreases erythema level on allergic contact dermatitis.

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The Clinical Study on 1 Case of Allergic Contact Dermatitis Treated with Infra-red Therapy and Acupuncture (경피적외선 조사요법과 침치료로 병행 치료한 알레르기성 접촉 피부염 환자 치험 1례)

  • Park, In-Sun;Jung, Hyun-A;Yoon, Il-Ji
    • Journal of Haehwa Medicine
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    • v.20 no.2
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    • pp.125-131
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    • 2012
  • The number of allergic contact dermatitis patients is steadily increasing but a proper reliability treatment guide is not prepared in Oriental Medicine. Also, the number of clinical cases on allergic contact dermatitis is not sufficient in Oriental medicine. As such, the facial flushing of allergic contact dermatitis which has been improved by infra-red therapy is significant in its treatment purpose. We reported on 43-year old male patient with allergic contact dermatitis. We treated him with herbal concoction, acupuncture, infra-red therapy and cupping therapy. We have received a good result in this case by using the combination of infra-red therapy. We reached a conclusion that using infra-red therapy can improve the facial flushing of patient with allergic contact dermatitis. However, further research on the effect of infra-red therapy for these symptoms is desired.

Effects of Sophorae Radix on skin condition in mice with contact dermatitis induced by Dinitrofluorobenzene (고삼(苦蔘) 추출물이 접촉피부염이 유발된 생쥐의 피부에 미치는 영향)

  • Kim, Hyungwoo;Ryu, Jeonghyun;Jo, Suzy;Cheon, Wonju;Son, Yonghae;An, Won Gun;Cho, Su In
    • The Korea Journal of Herbology
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    • v.28 no.6
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    • pp.25-29
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    • 2013
  • Objectives : The dried root of Sophora flavescens Aiton have been used to treat patient with skin diseases such as eczema in Eastern countries. S. flavescens can clear away heat and dry dampness and purge sthenic-fire from the liver and gallbladder. Recently, anti-allergic effect of S. flavescens has been reported. However, the effect on skin condition of contact dermatitis still remains unknown. Thus, the purpose of this study is to evaluate the efficacy of S. flavescens on contact dermatitis. Methods : In order to investigate the effects of S. flavescens (methanol extract of S. flavescens, MESR) on skin condition, the contact dermatitis was induced in mice skin by using 1-fluoro-2,4-dinitrofluorobenzene (DNFB). As the effective endpoints, skin thickness, skin weight, histopathological change were checked. In addition, effects on skin lesion, body weight and spleen/body weight ratio were also investigated. Results : Topical application of MESR ($500{\mu}g/day$) lowered skin thickness (P < 0.05) and skin weight (P < 0.05), respectively. MESR-treated group showed diminished spongiosis and immune cell infiltration in skin tissues compared to those of non-treated control group. The inhibition of skin lesions was also observed in MESR-treated group. In addition, MESR did not affect body weight gain and spleen/body weight ratio in contrast with those in dexamethasone-treated group. Conclusion : These data suggest that Sophorae Radix could improve skin lesion of contact dermatitis. This indicates the possibility for Sophorae Radix to be used to patients with skin diseases such as contact dermatitis.

Affecting Factors of End Colostomy-Related Complications (말단결장루의 합병증 발생 영향 요인)

  • Park, Seung Mi;Kim, Keum Soon
    • Korean Journal of Adult Nursing
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    • v.19 no.4
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    • pp.634-643
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    • 2007
  • Purpose: This study was performed to investigate the type and frequency of end colostomy-related complications and to identify the risk factors for those complications. Methods: Retrospective analysis of medical records was made in 708 patients who underwent end colostomy in Samsung Medical Center between October 1994 and February 2005. The type was divided into stomal and peristomal complications: stomal complications included bleeding, necrosis, mucocutaneous separation, prolapsed stoma, retraced stoma, stenosis, and hyperplasia; peristomal complications did peristomal varix, peristomal hernia, irritant contact dermatitis, allergic contact dermatitis, maceration, folliculitis, hyperplasia, bacterial infection, candidal infection, malignancy in the peristomal area, mechanical damage and pyoderma gangrenosum. Results: For stomal complications, hyperplasia was most common(9.0%). For peristomal complications, irritant contact dermatitis was developed in 17.4%. Sex and BMI were risk factors for irritant contact dermatitis, hyperplasia, peristomal hernia, flat stoma, and retracted stoma. Conclusion: Teaching for preventing irritant contact dermatitis such as proper pouching and peristomal skin protection, and for comprehensive weight control should be emphasized on self care program for ostomates, while ostomy care nurse should take a careful consideration of preoperative ostomy site marking in female obese patients.

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2 Cases of Occupational Contact Dermatitis (직업성 접촉 피부염 치험 2례)

  • Son, Jae-Wwoong;Yun, Young-Hee;Ko, Seong-Gyu;Choi, In-Hwa
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.29 no.4
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    • pp.169-181
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    • 2016
  • Objectives : The purpose of this case report is to know the effect of Korean medical treatments on occupational contact dermatitis. Methods : We reported 2 cases who visited Allergy and Derma-Cosmetic Clinic of Kyung Hee University Hospital at Gangdong. They were diagnosed with occupational contact dermatitis and treated by Korean medical treatment. Results : One patient recovered after 13 days of admission and total 9 months of outpatient period. Another patient recovered after 9 days of admission and total 7 months of outpatients period through Korean Medical Treatment. Conclusions : We may expect that Korean medical treatment had therapeutic effects on occupational contact dermatitis, but the additional study will be conducted for revealing the exact therapeutic effects.

A Case of Occupational Allergic Contact Dermatitis Caused by Mortar (모르타르로 인한 직업성 알레르기성 접촉성 피부염 치험 1례)

  • Eom, Ye-Jin;Hong, Chul-Hee
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.27 no.4
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    • pp.209-220
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    • 2014
  • Objectives : The purpose of this study is to report the effect of Korean medicine treatment on occupational allergic contact dermatitis caused by mortar. Methods : The patient treated by herbal medicine, acupuncture, pharmacopuncture and external therapy. The progress is evaluated by Numerical Rating Scale(NRS) and Dermatology Life Quality Index(DLQI). Results : NRS and DLQI score were significantly decreased as a result of Korean medicine treatment. Conclusions : Korean medicine treatment should be effective for the occupational allergic contact dermatitis caused by mortar. More studies are needed to confirm stability of these treatment.

A Clinical Case Report of Taeeumin Patient Diagnosed with Systemic Contact Dermatitis and Facial Flushing (전신성 접촉피부염과 안면홍조를 호소하는 태음인 환자 치험 1례)

  • Min-jung, Lee;Jiyeon, Lee;Min-woo, Hwang
    • Journal of Sasang Constitutional Medicine
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    • v.34 no.4
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    • pp.68-80
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    • 2022
  • Objectives This study is to report a significant improvement in a Taeeumin patient with systemic contact dermatitis after eating urushiol chicken by herbal medicine treatment. Methods The patient had complaints of erythema, swelling, pruritus, scaly skin, and facial flushing. We treated the patient with an herbal medicine 'Galgeunhaegi-tang' for three months. We evaluated the treatment outcome of systemic contact dermatitis using the Three Item Severity(TIS) score every visit and facial flushing by Image color summarizer at the first and last visit. Results After the treatment, the severity of the patient's skin complaints lessened from moderate to mild. The Image color summarizer showed a minor decrease in the normalized red color level and a significant increase in the brightness level and facial color percentage. Conclusions The patient diagnosed with systemic contact dermatitis, treated with Galgeunhaegi-tang for three months, showed a significant improvement in skin complaints with brighter and even facial color.