• Geomechanics and Engineering
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• v.29 no.6
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• pp.615-626
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• 2022

The soft clays are widely distributed, and one of the prominent engineering problems is the creep behavior. In order to predict the creep deformation of soft clays in an easier and more acceptable way, a simple creep constitutive model has been proposed in this paper. Firstly, the triaxial creep test data indicated that, the strain-time (𝜀-t) curve showing in the 𝜀-lgt space can be divided into two lines with different slopes, and the time referring to the demarcation point is named as t_EOP. Thereafter, the strain increments occurred after the time t_EOP are totally assumed to be the creep components, and the elastic and plastic strains had occurred before t_EOP. A hyperbolic equation expressing the relationship between creep volumetric strain, stress and time is proposed, with several triaxial creep test data of soft clays verifying the applicability. Additionally, the creep flow law is suggested to be similar with the plastic flow law of the modified Cam-Clay model, and the proposed volumetric strain equation is used to deduced the scaling factor for creep strains. Therefore, a creep constitutive model is thereby established, and verified by successfully predicting the creep principal strains of triaxial specimens.

• Proceedings of the Korean Society of Embryo Transfer Conference
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• 2002.11a
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• pp.96-96
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• 2002

We examined the role of SR 144528 (N-[-(1S-endo-1,3,,3-trimethyl-bicycle[2, 2, 1 ] heptan-2-y1]-5-(-4-chloro-3-mothyl-phenyl)-(4-methylbenzyl)-pyrazole-3- carboxamide) in the modulation of certain AC isoforms in transiently transfected COS-7 cells. We found that CB2 in COS cells has a constitutive activity, and thus leading to inhibition of AC-V activity even in the absence of agonist. In addition, this constitutive modulation of AC is reversed by SR144528. It is now well established that several G protein-coupled receptors can signal without agonist stimulation(constitutive receptors). Inverse agonists have been shown to inhibit the activity of such constitutive G protein-coupled receptor signaling. Agonist activation of the G$\_$i/o/-coupled peripheral cannabinoid receptor CB2 normally inhibits adenylyl cyclase type V and stimulates adenylyl cyclase type II. Using transfected COS cells, we show here that application of SR144528, an inverse agonist of CB2, leads to a reverse action (stimulation of adenylyl cyclase V and inhibition of adenylyl cyclase II). This inverse agonism of SR144528 is dependent on the temperature, as well as on the concentration of the cDNA of CB2 transfected. Pertussis toxin blocked the regulation of adenylyl cyclase activity by SR 144528.

• Earthquakes and Structures
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• v.25 no.1
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• pp.57-67
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• 2023

The buckling of longitudinal reinforcements under seismic loading accelerates the degradation of the bearing capacity of reinforced concrete columns. The traditional hysteretic constitutive model of reinforcement, which does not consider buckling, usually overestimates the seismic performance of pier columns. Subsequent researchers have also proposed many models including the buckling effects. However, the accuracy of these hysteretic constitutive models proposed for simulating the buckling behavior is inadequate. In this study, based on their works, the influence of historical events on buckling is considered, the path of the re-tensioning phase is corrected by adjusting the boundary lines, and the positions of the onset buckling point and compressive buckling path during each buckling deformation are corrected by introducing correction parameters and a boundary line. A modified hysteretic constitutive model is obtained, that can more accurately reflect the buckling behavior of reinforcements. Finally, a series of hysteresis tests of reinforcements with different slenderness ratios were then conducted. The experimental results verify the effectiveness of the proposed modified model. Indicating that the modified model can more accurately simulate the equivalent stress-strain relationship of the buckling reinforcement segment.

• Transactions of Materials Processing
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• v.33 no.1
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• pp.18-35
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• 2024

In the present work, the evolution rules for the internal variables including continuum damage factors are obtained using the thermodynamic framework, which are in turn facilitated to derive the elastic-plastic constitutive relation for the particulate composites. Using the Mori-Tanaka scheme, the homogenization on state and internal variables such as back-stress and damage factors is carried out to procure the rate independent plasticity relations. Moreover, the degradation of mechanical properties of constituents is depicted by the distinctive damages such that the phase and interfacial damages are treated individually accordingly, whereas the kinematic hardening is depicted by combining the Armstrong-Frederick and Phillips' back-stress evolutions. On the other hand, the present constitutive relation for each phase is expressed in terms of the respective damage-free effective quantities, then, followed by transformation into the damage affected overall nominal relations using the aforementioned homogenization concentration factors. An emphasis is placed on the qualitative analyses for strain localization by observing the perturbation growth instead of the conventional bifurcation analyses. It turns out that the proposed constitutive model offers a wide range of strain localization behavior depending on the evolution of various internal variable descriptions.

• Geomechanics and Engineering
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• v.15 no.5
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• pp.1081-1089
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• 2018

The deformation and strength of brittle rocks are significantly influenced by the crack closure behavior. The relationship between the strength and deformation of rocks under uniaxial loading is the foundation for design and assessment of such scenarios. The concept of relative crack closure strain was proposed to describe the influence of the crack closure behavior on the deformation and strength of rocks. Considering the crack compaction effect, a new damage constitutive model was developed based on accumulated AE counts. First, a damage variable based on the accumulated AE counts was introduced, and the damage evolution equations for the four types of brittle rocks were then derived. Second, a compaction coefficient was proposed to describe the compaction degree and a correction factor was proposed to correct the error in the effective elastic modulus instead of the elastic modulus of the rock without new damage. Finally, the compaction coefficient and correction factor were used to modify the damage constitutive model obtained using the Lemaitre strain equivalence hypothesis. The fitted results of the models were then compared with the experimental data. The results showed that the uniaxial compressive strength and effective elastic modulus decrease with an increase in the relative crack closure strain. The values of the damage variables increase exponentially with strains. The modified damage constitutive equation can be used to more accurately describe the compressive deformation (particularly the compaction stage) of the four types of brittle rocks, with a coefficient of determination greater than 0.9.

• Journal of the Korean Geotechnical Society
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• v.18 no.1
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• pp.141-152
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• 2002

Although a number of constitutive models have been proposed to define the behavior of geotechnical materials including elastic, plastic, and dynamic response, flew numerical models have been developed for the cyclic shear behavior of rock joints or interfaces. Such realistic constitutive models play an important role in analyzing and predicting the response of joints under dynamic loads. The purpose of this research is to verify the constitutive model modified for rough granite joints based on Disturbed State Concept(DSC) model, which has been successfully verified with respect to other materials such as dry sand-steel interface and wet sand-concrete interface. Furthermore, DSC model is compared and verified with respect to cyclic shear tests and numerical analysis results based on Plesha model. Based on the results of this research, it can be stated that DSC model is capable of characterizing the cyclic shear behavior of rough granite joints under dynamic loads.

• Korea-Australia Rheology Journal
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• v.16 no.4
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• pp.183-191
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• 2004

High Deborah or Weissenberg number problems in viscoelastic flow modeling have been known formidably difficult even in the inertialess limit. There exists almost no result that shows satisfactory accuracy and proper mesh convergence at the same time. However recently, quite a breakthrough seems to have been made in this field of computational rheology. So called matrix-logarithm (here we name it tensor-logarithm) formulation of the viscoelastic constitutive equations originally written in terms of the conformation tensor has been suggested by Fattal and Kupferman (2004) and its finite element implementation has been first presented by Hulsen (2004). Both the works have reported almost unbounded convergence limit in solving two benchmark problems. This new formulation incorporates proper polynomial interpolations of the log­arithm for the variables that exhibit steep exponential dependence near stagnation points, and it also strictly preserves the positive definiteness of the conformation tensor. In this study, we present an alternative pro­cedure for deriving the tensor-logarithmic representation of the differential constitutive equations and pro­vide a numerical example with the Leonov model in 4:1 planar contraction flows. Dramatic improvement of the computational algorithm with stable convergence has been demonstrated and it seems that there exists appropriate mesh convergence even though this conclusion requires further study. It is thought that this new formalism will work only for a few differential constitutive equations proven globally stable. Thus the math­ematical stability criteria perhaps play an important role on the choice and development of the suitable con­stitutive equations. In this respect, the Leonov viscoelastic model is quite feasible and becomes more essential since it has been proven globally stable and it offers the simplest form in the tensor-logarithmic formulation.

• Composites Research
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• v.29 no.3
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• pp.91-97
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• 2016

In this paper, impulse-momentum theory was coupled to a constitutive equation both for implementing quasi-static and impact characteristics of EPP (Expanded polypropylene). Also, parameters which have physical meanings were expressed as functions of relative density. Simultaneous nonlinear Newton-Raphson method was applied to find the proper values for parameters in the constitutive equation along with quasi-static test data. Results from the impulse-momentum theory coupled constitutive equation showed good agreement with experimental data and the potential to be applied to different material type polymeric foam.

• Plant Biotechnology Reports
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• v.3 no.4
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• pp.325-331
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• 2009

To efficiently express a gene of interest in transgenic plants, the choice of promoter is a crucial factor as it directly affects the expression of the transgene that will yield the desired phenotype. The Arabidopsis ${\beta}-carotene$ hydroxylase 1 gene (AtBch1) shows constitutive and ubiquitous expression and was thus selected as one of best candidates for constitutive promoter analysis by both in silico northern blotting and semi-quantitative RT-PCR analysis. To investigate AtBch1 promoter activity, the 1,981-bp 5'-upstream region of this gene was fused with ${\beta}-glucuronidase$ (GUS) and transformed into Arabidopsis. Through the molecular characterization of transgenic leaf tissues, the AtBch1 promoter generated strong activity that drives 1.8- and 2-fold higher GUS expression than the cauliflower mosaic virus 35S (35S) promoter at the transcriptional and translational levels, respectively. Furthermore, the GUS enzyme activity driven by the AtBch1 promoter was 2.8-fold higher than that produced by the 35S promoter. By histochemical GUS staining, the ubiquitous expression of the AtBch1 promoter was observed in all tissues of Arabidopsis. Semi-quantitative RT-PCR analysis with different tissues further showed that this promoter serves as a strong constitutive driver of transgene expression in dicot plants.

• Magazine of the Korean Society of Agricultural Engineers
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• v.34 no.1
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• pp.41-48
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• 1992

Various soil behaviors usually occurring in the geotechnical problems, such as, cutting and embankments, stability of slope, seepage, consolidations, shearing failures and liquefaction, should be predicted and analyzed in any way. An approach of these predictions may be followed by the development of the constitutive equations as first and subsequently solved by numerical methods. The purpose of this paper is develop the constitutive equation of sands uder monotonic or cyclic loadings. The constitutive equation which is based on elasto-plastic theory, modified anisotropic consolidated stress parameter by Sekiguchi et al and Pender's theory is derived. And the equation is included a new stress parameter, hardening function, Bauschinger's effects and Pender's theory. The model is later evaluated and confirmed the validity by the test data of Ottawa sand, Banwol sand Hongseong sand. The following conclustions may be drawn: 1. The consititutive equation which is based on elasto-plastic theory, modified anisotropic consolidated stress parpameter by Sekiguchi et al and Pender's theory is derived. The equation in included a new stress parameter, hardening function, Bauschinger's effect and Pender's theory. 2. For Ottawa sand, the result of the constitutive equation shows a better agreement than that of Oka et al. The result of axial strain agrees well with the tested data. However, the result of horizontal strain is little bit off for the cyclic loadings or large stress. It is thought that the deviation may be improved by considering Poisson's ratio and precise measurement of shear modulus. 3. Banwol sand is used for the strain and stress tests with different relative densitites and confining pressures. The predeicted result shows a good agreement with the tested data because the required material parameters were directly measurd and determined form this laboratory. 4. For Hongseong sand, the tests under same amplitude of cyclic deviatoric stress shows a similar result with the tested data in absolute strain. It shows the acute shape of turning point because the sine wave of input is used in the test but the serrated wave in prediction.