• Biomolecules & Therapeutics
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• 제5권2호
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• pp.194-201
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• 1997

The hepatoprotective activity of six extracts (BE, EE, HH, PS-1, PS-2, KP) from Artimisia iwayomogi was investigated against experimentally produced hepatic damages. Silymarin, DDB and UDCA were used as reference compounds. Treatment with PS-1 extract reduced hepatic demages induced by $CCl_4$, acetaminophen and ANIT but it did not alter ethionine-induced hepatotoxicity In addition, PS-1 extract showed a protective effect against chronic $CCl_4$-induced hepatotoxicity as well as liver regeneration. PS-2 and KP extracts exhibited significant antihepatotoxic effects on D-galactosamine-induced hepatitis. Treatment with EE extract inhibited ethionine-induced fatty liver. These data indicate that the PS-1 extract is the roost hepato-protective constituent and rationalize the traditional use of this plant in hepatobiliary disorders.

• 한국근적외분광분석학회:학술대회논문집
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• 한국근적외분광분석학회 2001년도 NIR-2001
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• pp.1616-1616
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• 2001

To select kernels for breeding that have required constituent content from either naturally distributed samples or artificially mutated ones, it is necessary to process batch samples in a short time. The constituent content of single-kernel grains such as wheat and rice has been determined using conventional bench type NIR instruments; however, it takes a lot of time and effort. Shizuoka Seiki (Fukuroi-city, Japan) and NFRI (National Food Research Institute) of MAFF (Ministry of Agriculture, forestry and Fisheries of Japan) have jointly developed a continuous high-speed single-kernel brown rice sorting machine based on rice protein content. It consists of several sections such as a feeding mechanism, measuring unit, sorting mechanism and controlling PC. The feeding mechanism picks up single-kernel brown rice from the hopper (maximum of 5kg storage capacity) and sends it to the measuring unit. A spectrum of the brown rice is obtained in the measuring unit, which consists of a near-infrared array sensor. The brown rice is then sorted in the sorting mechanism based on its protein content estimated by the controlling PC. In the present study, measuring speed was approximately 500ms for the full spectrum range and overall sorting speed was approximately 2.8s for one kernel. Accuracy of estimation was approximately SEP=0.5% of dry matter protein content for nonglutinous rice.

• 한국의류학회지
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• 제34권10호
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• pp.1611-1620
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• 2010

This research compares the difference of each preference segments' subjective hands and sensibilities in order to analyze the correlations among preference, subjective hands, and sensibilities. Preference segments were classified into wool, acrylic, and long stitch length-preferred clusters in previous research. To evaluate the subjective hands and sensibilities of knit fabrics, the 20's and 30's women rated twelve knit fabrics by touching, using a questionnaire with a seven-point semantic differential scale. These twelve knit fabrics were differentiated by controlling the mixture ratio and stitch length using a computer-controlled automatic flat knit machine. The difference of each preference segments' subjective hands and sensibilities was determined using the conjoint analysis. The clusters perceived the subjective hands and sensibilities differently according to preferred constituent characteristics. There was no correlation between surface unevenness and preference in wool-preferred cluster, while there were negative correlations in other clusters. The acrylic-preferred cluster had a preference in coolness compared to other clusters; in addition, the long stitch-preferred cluster preferred flexibility/bulkiness and extensibility than the others. All clusters preferred modem and natural sensibilities that were caused by different constituent characteristics of knit fabrics.

• 대한한의학방제학회지
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• 제11권2호
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• pp.147-158
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• 2003

This study aimed to investigate the effect of each constituent-herb of Sagoonja-Tang on the plasma corticosterone level in mice exposed to heat stress. Each formula(0.5g/kg, 1.0g/kg) was injected intragastrically to mice exposed to forced hot water swimming(42$^{\circ}C$, 3min) before measuring the change of plasma corticosterone level of mice. The results were as follows: 1. At 15 minutes after the heat stress for 3 minutes the most significant increase of corticosterone level was shown. 2. Ginseng group didn't show significant changes. 3. Atractylodis group showed significant decrease at 0.5g/kg dose(P<0.05). But it showed slightly increase at 1.0g/kg dose. 4. Poria group didn't show significant changes. 5. Glycyrrhizae group showed slightly increase, but insignificant. These data revealed that Atractylodis macrocephalae Rhizoma might have the anti-stress effect through the control of plasma corticosterone level in mice exposed to heat stress.

• 대한한의학방제학회지
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• 제11권2호
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• pp.83-94
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• 2003

This study aimed to investigate the effects of each constituent-herb of Sagoonja- Tang on the plasma corticosterone level in mice exposed to cold stress. Sagoonja-Tang is composed of Ginseng Radix, Atractylodis Radix, Poria, and Glycyrrhizae Radix. Each constisuent-herb(0.5g/kg, 1.0g/kg) was administered intragastrically to mice 1hr prior to expose to forced cold water swimming($4{\circ}C$, 3min) before measuring the change of plasma corticosterone level of mice. The results were as follows: 1. At 30 minutes after the cold stress for 3 minutes the most significant increase of corticosterone level was shown. 2. Ginseng group(PGR group) didn't show any significant changes. 3. Atractylodis group(AR group) showed significant decrease at 0.5g/kg dose (P<0.01). But it didn't show significant changes at 1.0g／kg dose. 4. Poria group(P group) didn't show significant changes. But it showed slightly increase at 1.0g/kg dose. 5. Glycyrrhizae group(GR group) didn't show significant changes. These data revealed that Atractylodis macrocephalae Rhizoma might have the anti-stress effect through the control of plasma corticosterone level and the dose of herbs had a different effect on the plasma corticosterone level in mice exposed to cold stress.

• 대한한방내과학회지
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• 제13권2호
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• pp.1-15
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• 1992

This study has been carried out to investigate the effects of Banhaonpaetang extract and its constituent herbs on the contractile force of Isolated Guinea pig trachea smooth muscle and to elucidate its mechanism. The results were as follows; 1. Banhaonpaetang significanly inhibitd the contractile force of isolated guinea pig trachea smooth muscle pretreated by histamine. 2. Banhaonpaetang significantly inhibited the contractile force of isolated guinea pig trachea smooth muscle pretreated by acetylcholine. 3. Radix Asari(細辛), Flos Inulae(旋覆花), Pericarpium Citri Nobilis(陳皮) and Radix Ginseng(人蔘) extract significantly inhibited the contractile force of isolated guinea pig trachea smooth muscle pretreated by histamine. 4. Radix Asari(細辛), Cortex Cinnamomi(桂心), Flos Inulae(旋覆花), Pericarpium Citri Nobilis(陳皮) and Radix Ginseng(人蔘) extract significantly inhibited the contractile force of isolated guinea pig trachea smooth muscle pretreated by acetylcholine. 5. The effects of Banhaonpaetang extract on the changes of plasma ACTH in rats were shown to be insignificant. 6. The effects of Banhaonpaetang extract on the changes of serum electrolytes were shown to be significant in $K^+$ and $Ca^{2+}$.

• 대한수학교육학회지:학교수학
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• 제15권1호
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• pp.15-35
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• 2013

본 연구의 목적은 중학생용 수학학습양식 판별도구를 개발하여 선호유형을 범주화하는 것이다. 개발된 수학학습양식 판별도구로 976명의 중학생을 대상으로 설문조사하여 16가지의 수학학습양식 유형이 존재하는지를 확인하였고 이를 선행 연구들과 비교 분석하였다. 또한 수학학습양식의 각 요인에 따른 양식별 남녀 학습자, 학년별 학습자의 분포에 어떠한 차이가 있는지 분석하였다. 수학학습양식 판별도구를 통해서 학습자의 인지적 정의적 학습양식을 파악함으로써 수학학습에 대한 학습자 특성을 전체적으로 파악하여 획일화된 수업형태에서 벗어나 개별화 수업으로 나아갈 수 있는 방향을 제시하고자 한다.

• 한국안전학회지
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• 제32권4호
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• pp.1-6
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• 2017

Functionally Graded Materials (FGM) as advanced heterogeneous composite materials have a higher performance than a conventional composite or bimaterial composite under some severe environments. As a heterogeneous material, FGM is commonly used in spacecraft, defense, nuclear and automotive industries due to its excellent properties. The purposes of this study are to evaluate the stress distribution and crack behaviors by the multiscale simulation. FGM contains two or more than two materials that the composition is structured continuously. Two types of FGM model are suggested, which are created by arbitrary prediction of the volume fraction and the exponential function. Aluminum as the metal matrix constituent and silicon carbide as the ceramic particle constituent are structured gradually by two types and the three point bending test also estimated. Moreover, two kinds of crack location were introduced in order to get the influences of material property distribution on the stress intensity factor. From the results we found that the stress intensity factors are increased in the case from softer to stiffer material, while vice versa.

• Structural Engineering and Mechanics
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• 제34권4호
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• pp.525-539
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• 2010

Polymer matrix composites are widely used in many engineering applications as they can be customized to meet a desired performance while not only maintaining low cost but also reducing weight. Polymers can experience viscoelastic-viscoplastic response when subjected to external loadings. Various reinforcements and fillers are added to polymers which bring out more complexity in analyzing the timedependent response. This study formulates an integrated micromechanical model and finite element (FE) analysis for predicting effective viscoelastic-viscoplastic response of polymer based hybrid composites. The studied hybrid system consists of unidirectional short-fiber reinforcements and a matrix system which is composed of solid spherical particle fillers dispersed in a homogeneous polymer constituent. The goal is to predict effective performance of hybrid systems having different compositions and properties of the fiber, particle, and matrix constituents. A combined Schapery's viscoelastic integral model and Valanis's endochronic viscoplastic model is used for the polymer constituent. The particle and fiber constituents are assumed linear elastic. A previously developed micromechanical model of particle reinforced composite is first used to obtain effective mechanical properties of the matrix systems. The effective properties of the matrix are then integrated to a unit-cell model of short-fiber reinforced composites, which is generated using the FE. The effective properties of the matrix are implemented using a user material subroutine in the FE framework. Limited experimental data and analytical solutions available in the literatures are used for comparisons.

• 약학회지
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• 제57권3호
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• pp.167-172
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• 2013

Insampaedoksan (IS) is the decoction of medicinal herbs, which was commonly used for anti-inflammatory and anti-pyretic in the Korean traditional medicine (KTM). Several studies on improving efficiency or searching new efficiency by fermenting traditional herbal medicines are recently in progress. The bioconversion has been conducted on IS using various bacteria. Liquiritin, ferulic acid, hesperidin, liquiritigenin, and glycyrrhizin in IS before and after fermented IS were simultaneously analyzed. These compounds were qualitatively analyzed and quantitatively analyzed using the HPLC-DAD system. The identifications of liquiritin, ferulic acid, hesperidin, liquiritigenin and glycyrrhizin were achieved by comparing the HPLC retention time ($R_t$) and the UV absorption of five pure compounds in the IS. As a result, the increased constituents were identified to be liquiritin, liquiritigenin and glycyrrhizin, while the decreased constituent was ferulic acid and the constituent of hesperidin was similar to before and after fermentation. Insampeadock-san fermented by Lactobacillus plantarum KFRI 144 exhibited the most remarkable changes in all of fermentation.