• 대한한방종양학회지
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• 제4권1호
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• pp.147-158
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• 1998

Clinical studies were carried out 40 cases of patients with stomach cancer treated by "Hangammyunyouk I(抗癌免疫1號方)", from September 1th 1997 to May 1th 1998. The results were summarized as follows; 1. Distribution of those attached by stomach cancer, by sex, showed that Male is more then Female, by age, showed that the number of fifties is majority. 2. Distribution of diagnostic stage, on descending order, stage III, stage IV. 3. Distribution of treatment attached by stomach cancer, in descending order: Chemotherapy and operation, chemotherapy, Radiation therapy and operation. 4. After taken herb medicine, the effects according to the symptoms were as follows; Nausea and Vomiting, Constipation, General body weakness, Average efficacy of symptoms were 68.1%. 5. Analysis of hematology attached by stomach cancer, increasing of WBC(61.5%), Hgb(54.5%), Platelet(62.5%) were observed.

• 대한기관식도과학회지
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• 제9권1호
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• pp.60-66
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• 2003

Although there is a wide range of diseases caused by gastric acid reflux and the number of cases is on the rise, it is difficult for the laryngologist to make the correct diagnosis. The treatment for laryngopharyngeal reflux can be grouped into 3 categories - changes in lifestyle, medication, and surgery. The medication used to treat laryngopharyngeal reflux are prokinetic agents and acid supressive agents such as antacids, H2 blockers, and PPIs(Proton pump inhibitor). Rabeprazole sodium($Pariet^{\circledR}$) is a newly developed agent belonging to the PPI group, but in contrast with the existing drugs such as omeprazole, lansoprazole, pantoprazole, has a low dependency on CYP2C19 during the metabolic cycle. Thus, it is known to have a quick but fixed antiacid effect and less individual differences. We analyzed 2166 patients from 32 hospitals who were prescribed $Pariet^{\circledR}$ from May, 2001 to April, 2002. The patients were divided into 4 groups according to the duration of treatment - Group 1: 1-14 days, Group 2: 15-28 days, group 3: 29-56 days, Group 4: more than 56 days. The cases were then analyzed for improvement of 8 symptoms(heart bum, regurgitation, chronic cough, hoarseness, globus sensation, chronic throat clearing, sore throat, and dysphagia), improvement on laryngoscope, usefulness to the doctor, and complication development. Of the total of 2116 patients, 1627(75.1%) cases showed at least 50% improvement of symptoms and the amount of improvement increased according to the duration of medical treatment. Most of the patients showed objective improvement on the laryngoscope, with 32.9% showing significant improvement and 38.7% showing moderate improvement. 37.6% of the doctors questioned replied that $Pariet^{\circledR}$ was very useful and 50.3% said it was useful, showing that most were satisfied with the treatment results. The complications known to develop after taking PPI are headache, nausea, diarrhea, abdominal pain, constipation, dizziness, fatigue, and of these, only a small percentage of the patients complained of mild headache. $Pariet^{\circledR}$ has shown to be a relatively safe and effective drug for the treatment of laryngopharyngeal reflux.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7683-7688
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• 2015

Background: The study evaluated the patient, lifestyle and tumor profile in patients undergoing upfront surgery for sporadic colorectal cancer (CRC) in Indian population. Materials and Methods: One hundred consecutive patients were included. Details related to their demographic profile, habits, signs and symptoms, tumor profile, further treatment and follow up were recorded. Results: The majority of the patients had colonic cancer (68%), advanced tumor stage 3 & 4 (46%), moderately differentiated tumors (70%) with absence of lymphatic invasion (60%) and metastasis (90%). Correlations between tumor location and abdominal pain (p-value 0.002), bleeding per rectum (p-value <0.001), difficulty in micturition (p-value 0.012) and constipation (p-value 0.007) were found to be statistically significant. Abdominal pain was more frequently reported in patients with metastasis (p-value 0.031). Loss of weight statistically correlated with absence of lymphatic invasion (p-value 0.047). Associations between tumor stage and alcohol intake (p-value 0.050) and non vegetarian diet (p-value 0.006); lymphatic invasion and intake of spicy food (p-value 0.040) and non vegetarian diet (p-value 0.001) and metastasis and alcohol intake (p-value 0.041) were also observed. Age and tumor grade were also correlated (p-value 0.020). Conclusions: Minimizing the adverse lifestyle factors can help in reducing the overall incidence of CRC in the Indian population.

• 대한간호학회지
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• 제27권2호
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• pp.389-400
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• 1997

This study examined the effects of group social support on the reduction of burden and increase in well-being of mothers of developmentally delayed children. The research used a one group pre-pose experimental design. The independent variable in the experiment was group social support. Two series of 4-weekly meetings for group social support were conducted by the researcher with the intention of developing a self-help group. The dependent variables were burden and well-being. Well-being was operationalized as physical symptoms and quality of life. Thirty mothers of developmentally delayed infants from the rehabilitation center of a medical center participated in the study. Data were collected by interviews and a self-administered questionnaire. The mean age of the subjects was 29.9 years. Changes of the dependent variables between pre and post tests were compared using the t-test. Even though there was a slight improvement in the scores for the dependent variables, they were not statistically significant. The items, "I resent my baby". "I feel angry about my interactions with my baby", "I feel guilty in my relationship with my baby" showed a significant decrease in burden score and were statistically significant. Symptoms of loneliness, constipation, anxiety, restlessness were less and feeling of happiness was greater after participation in the group social support, than on the pretest. The mothers showed emotional instability and frustrations during the group sessions but their reactions in general were positive. Emotional support, stress management and information provided were identified as the most valuable content of the sessions. However, participation was not active due to the mother's denial, delayed acceptance and /or avoidance of their infants' problems. It can be seen that group social support for the mothers with developmentally delayed children should be provided after infancy when the mothers have time to accept their children's conditions and are ready to receive support. The use of comprehensive instruments which measure burden in both families and mothers needs to be developed for future research.

• 사상체질의학회지
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• 제19권2호
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• pp.195-203
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• 2007

1. Objectives The purpose of this study is to evaluate the effects of Gihwangbaekho-tang which is based on the Sasang Constitutional Medicine for the patient who has suffered from hip joint pain. 2. Methods The subject is about 86-year-old patient suffering from hip joint pain who was diagnosed as Soyangin interior over heated disease based on his Nature & Emotion, physical characteristics, symptoms, and we have prescribed Gihwangbaekho-tang. We used Visual analogue scale(VAS) for the assessment of Hip joint pain. 3. Results and Conclusions The patient was treated with Gihwangbaekho-tang and hip joint pain, thirst, redness of the face, constipation and general condition were improved. This study describes tile improvement of Hip joint pain and the change of symptoms by using Gihwangbaekho-tang. In this study, we applied Gihwangbaekho-tang to 86-year-old patient for about forty days, and Gihwangbaekho-tang didn't cause any serious side effect on the patient.

• 사상체질의학회지
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• 제27권1호
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• pp.138-148
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• 2015

Objectives This study was conducted in order to analyze the distribution of Sasang constitution, herbmed, exterior-interior disease and concomitant symptoms of 36 facial nerve paralysis patients. Methods A clinical study was done on 36 patients, treated as facial nerve paralysis. Sasang constitution specialist diagnosed their constitution and gave prescription. Degree of improvement was evaluated by assessment scale or change of patient's complaint. Results 1) Distribution of sasang constituion : Taeeumin 21 patients, Soyangin 8 patients, Soeumin 7 patients. 2) Distribution of exterior-interior disease : Taeeumin and Soeumin were diagnosed as interior disease more than exterior disease, Soyangin was reverse. 3) Hyeongbangdojeok-san and Hyeongbangjihwang-tang (Soyangin), Galgeunhaegi-tang(Taeeumin) and Gwakhyangjeonggi-san(Soeumin) were used the most in each sasang constitution. 4) Seventeen patients had concomitant symptoms : digestive disorder, sleep disorder, tinnitus, hypertension, diplopia, itching, gout, neck-shoulder pain, constipation and dizziness. Conclusions Patients had different Sasang constitution and in the same Sasang constitution, they had different symptomatology.

• 대한한방내과학회지
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• 제12권1호
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• pp.155-165
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• 1991

On the treatment of C.V.A, I obtain the results through the bibliographic investigation in the method of Chong-Yol-Sa-Hwa as follows ; 1. The method of Chong-Yol-Sa-Hwa on the treatment of CVA. is used for the occation of flaming fire in the heart caused by fire emotions in excess (五志過極), difficiency of Yin, flaming up of excessive in liver and plegm-heat. 2. The representative symptoms which can be used by the method of Chong-Yol-Sa-Hwa are firerishness, redness on face, foul breath, fidgets, angry, high fever, constipation slimy and greasy yellow coat of the tongue, and the pulse shaped on full-rapid (洪數), tautsmaooth and rapid (弦滑血數). 3. The general prescription on the method of Chong-Yol-Sa-Hwa are Bang pung tong sung-San, Yangkyuk-San, Backho-Tang, Sosiho-Tang, Samhwa-Tang, Chibo-Tan and Woohwang chongsim-Hwan on excessive symptom-complex, Yookmichihwang-Tang-Kakam, Samool-Tang-Kakam and Youngyangkak-Tang on insufficency symptom complex. 4. The most frequently dosed medicinal plants are Seok-ko, Chi-mo, Dae-Hwang, Mang-cho, Hwang-kewm, Hwang-back, Chi-ja, Si-ho, Han-Su-Seok, Yong-Tam-Cho, Mok-Tan-Pi and Saeng-Chi-Hwang. 5. The method of chong-Yol-Sa-Hwa might be expressed good medicinal effects adopted on the symptoms or flaming evil fire (火旺) after awakend and ‘Yang’ occlusion of Chung-Chang-Pu (中臟脈) which is accompanied with the method of purgation, break through the plegm, resuscitate and nourishing the Yin.

• 동의생리병리학회지
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• 제34권5호
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• pp.215-221
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• 2020

Adulterated herbal medicine is intentionally added with undeclared improper or inferior ingredients which should not be in herbal medicine. The contamination with potentially hazardous substances such as heavy metal, pesticides, fungus, and microorganism sometimes can be regarded as one of adulteration in a broad sense. The problem of adulteration is that adulterated herbal medicine shows poor quality and/or can cause adverse events. Therefore, it is important to control adulteration issues for quality assurance and qualitative improvement of herbal medicines. This study aims to summarize and make a reference how to control adulterated herbal medicine. In this process, this study is to investigate studies about adulterated herbal medicine via searching Korean and foreign electronic databases such as PubMed, NDSL and OASIS. Finally eighteen papers were included to this study and analyzed according to the type of study, the category and efficacy of adulterants, the type of analysis methodologies and possible adverse events of adulterants. Phosphodiesterase type 5 (PDE-5) inhibitors for male sexual enhancement and anorexic, laxative, diuretic agents for weight loss and treating obesity has been used frequently as adulterants. The range of adverse event caused by adulterated herbal medicine were very wide from mild symptoms such as diarrhea, constipation, dizziness and blurred vision to very severe symptoms such as heart failure, hypoglycemia and renal impairment. This study showed the recent trend on the research of adulterated herbal medicine and this will be the ground to develop more detailed systems to control adulterated herbal medicine.

• 동의생리병리학회지
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• 제37권6호
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• pp.165-171
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• 2023

COVID-19 infection heightens the risk of thromboembolism. To see the similarities between the COVID-19 infection and Taeyang blood retention pattern, we conducted a PubMed search using specific terms related to blood circulation issues in the context of COVID-19, summarizing findings from 13 cases and 4 observational studies involving actual patients. Patients with COVID-19 are at risk of blood coagulation due to factors such as viral-induced cytokine storms, vascular endothelial dysfunction, reduced mobility in bedridden or isolated individuals, and resulting constipation. Additionally, cytokine storms and severe inflammation can lead to delirium in COVID-19 patients. The Taeyang blood retention pattern manifests as symptoms arising from delirium and an increased blood coagulation tendency in patients with a robust immune response. According to the Sanghan theory, certain herbal treatments can alleviate symptoms in patients with a tight lower abdomen who do not experience urinary issues. Studies show that components like Persicae Semen and Rhei Redix et Rhizoma in these prescriptions enhance blood circulation and reduce hypercoagulability. Additionally, these treatments aim to promote blood flow by relieving abdominal pressure through facilitating bowel movements. The excessive inflammation and heightened blood coagulation tendency in COVID-19 resemble the Taeyang blood retention pattern, although they are caused by different pathogens. Reinterpreting classical oriental medicine's principles in a modern context may enhance our understanding of traditional East Asian Medicine and foster future developments.

• 동서간호학연구지
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• 제13권2호
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• pp.79-91
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• 2007

Purpose: To improve health care of the elderly, we have used Moxibustion to examine the effectiveness of this product from 1st Feb. 2007 to 31 st May for 78 people who are older than 65 years old twice a week. Method: The tool of research was modified Cornell Medical Index(CMI) which Nam Ho Chang(1965) modified for the Korean and CMI which consists of 26 questions. Data were analyzed in frequency, paired t-test by SPSS. Result: Hypothesis: 'It was supported that CMI increases for those who have treated Moxinustion'. There were significant differences between before and after using Moxibustion when the symptom is one of those which are sore throat, tonsillar, edema, tightness of nose, common cold, cough, tightness of chest, palpitation, dyspnea, edema of leg, difficulty of urination, anorexia, heavy on stomach, nausea, vomiting, dyspepsia, fullness of abdomen, stomachache, diarrhea, constipation, incontinency of stool, arthralgia, shoulder or backache, lumbago, headache, burning or chillness, vertigo and dizziness. Conclusion: As a result, Moxibustion is effective for such symptoms so that it is considered to be using in everyday life this product for better health care.