Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Pathological Mechanism of Taeyang Blood Retention Pattern Based on Cases of Thrombosis in Patients with COVID-19 Infection : A Literature Review

코로나19 감염증 환자의 혈전 사례를 바탕으로 본 태양병 축혈증의 병리기전에 관한 문헌고찰

  • Miso Park (Clinical Trial Center, Daejeon Korean Medicine Hospital of Daejeon University) ;
  • Jungeun Choi (Clinical Trial Center, Daejeon Korean Medicine Hospital of Daejeon University) ;
  • Junghyo Cho (Department of Hepatology and Hematology of Korean Medicine, College of Korean Medicine, Daejeon University) ;
  • Horyong Yoo (Department of Cardiology and Neurology of Korean Medicine, College of Korean Medicine, Daejeon University) ;
  • Ji-Yeon Lee (Department of Obstetrics and Gynecology of Korean Medicine, College of Korean Medicine, Daejeon University)
  • 박미소 (대전대학교 대전한방병원 임상시험센터) ;
  • 최정은 (대전대학교 대전한방병원 임상시험센터) ;
  • 조정효 (대전대학교 한의학과 간계내과학교실) ;
  • 류호룡 (대전대학교 한의학과 심계내과학교실) ;
  • 이지연 (대전대학교 한의학과 부인과학교실)
  • Received : 2023.09.11
  • Accepted : 2023.11.06
  • Published : 2023.12.25
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Abstract

COVID-19 infection heightens the risk of thromboembolism. To see the similarities between the COVID-19 infection and Taeyang blood retention pattern, we conducted a PubMed search using specific terms related to blood circulation issues in the context of COVID-19, summarizing findings from 13 cases and 4 observational studies involving actual patients. Patients with COVID-19 are at risk of blood coagulation due to factors such as viral-induced cytokine storms, vascular endothelial dysfunction, reduced mobility in bedridden or isolated individuals, and resulting constipation. Additionally, cytokine storms and severe inflammation can lead to delirium in COVID-19 patients. The Taeyang blood retention pattern manifests as symptoms arising from delirium and an increased blood coagulation tendency in patients with a robust immune response. According to the Sanghan theory, certain herbal treatments can alleviate symptoms in patients with a tight lower abdomen who do not experience urinary issues. Studies show that components like Persicae Semen and Rhei Redix et Rhizoma in these prescriptions enhance blood circulation and reduce hypercoagulability. Additionally, these treatments aim to promote blood flow by relieving abdominal pressure through facilitating bowel movements. The excessive inflammation and heightened blood coagulation tendency in COVID-19 resemble the Taeyang blood retention pattern, although they are caused by different pathogens. Reinterpreting classical oriental medicine's principles in a modern context may enhance our understanding of traditional East Asian Medicine and foster future developments.

Keywords

Acknowledgement

이 논문은 2023학년도 대전대학교 교내학술연구비 지원에 의해 연구되었음.

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