• 대한본초학회지
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• 제22권1호
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• pp.81-87
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• 2007

Objectives: Angelicae Dahuricae Radix (Baek-Ji in Korean, BJ) is well known to be used as a medicine for cold, headache, supraorbital pain, nasal congestion, and toothache. Little is understood about the roles of BJ in the cytokine and chemokine secretion by immune cells. This study was designed to find out the effects of BJ on the cytokine and chemokine secretion in human mast cells (HMC). Methods : We treated BJ according to consistency on HMC and measured cytokines and chemokines levels using flow cytometry CBA system. Results: In BJ treated group. the expression of interferon-inducible protein 10 (IP-l0), monocyte chemoattractant protein-1 (MCP-1), chemokine (C-X-C motif) ligand 9 (MIG), and interleukin 10 (IL-l0) levels were decreased significantly and chemokine (C-C motif) ligand 5 (RANTES), IL-8, $interferone-{\gamma}$ ($IFN-{\gamma}$), and tumor necrosis factor alpha (TNF-a) were decreased significantly. Conclusion : The results of this experiment supposed that the treatment of BJ will ameliorate the secreting levels of some chemokines or cytokines such as IP-10, MCP-1, MIG, IL-10, RANTES, IL-8, $IFN-{\gamma}$, and TNF-a.

• 대한조선학회논문집
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• 제38권1호
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• pp.27-36
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• 2001

현재, 유럽에서 중요한 역할을 담당하고 있는 수송모델로서 바다와 강을 연계한 Sea-river 수송모델은 황해권 지역에서의 국내 외 화물수송과 여객수송에 있어 장래에 매우 중요한 역할을 할 것이다. 본 연구에서는 육상수송에 따른 국내 교통 혼잡문제와 극동아시아 국가의 화물량 증대로 인한 물류 문제의 개선을 위해 경인운하의 운항조건에 적합한 sea-river 연계 바아지선단의 수송모델을 제안한다. 즉, 본 연구에서는 경인운하의 형상과 크기 등의 제한조건 등을 고려하여 바아지선단의 수송효율 측면의 경제성을 바탕으로 경인운하를 이용한 황해권의 sea-river 연계 수송모델로서 효율적인 바아지선단 구성의 표준화를 제시하고자 한다.

• KCI Concrete Journal
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• 제12권2호
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• pp.73-84
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• 2000

A new form of construction utilizing structural steel as the boundary elements in ductile flexural concrete walls is proposed to solve the bar congestion problems in such a heavily reinforced region, while maintaining the ductility and energy absorption capacity comparable to their traditional form. Two wall specimens containing rectangular hollow structural sections (HSS) and channels at their ends respectively, and one companion standard reinforced concrete wall specimen with concentrated end reinforcement were constructed and tested under reversed cyclic loading to evaluate the construction process as well as the structural performance. Initially, all three specimens were chosen and detailed with some caution to have approximately the same flexural capacity without change of the original shape and dimension of a rectangular cross section correction. Analysis and comparison of test results indicated that the reversed cyclic responses of three walls showed similar hysteretic properties, but in those with steel boundaries, local buckling of the corresponding steel webs and flanges following significant yielding was a dominant factor to determine the hysteretic response. The monotonic and cyclic responses predicted based on a sectional approach was also presented and found to be in good agreement with measured results. Design recommendations considering local instability of the structural steel elements and the interaction between steel chords and a concrete web member in such a composite wall are presented.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2008년도 동계학술발표대회 논문집
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• pp.67-70
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• 2008

As a part of the project on road tunnel fire safety system development, Quantitative Risk Assessment program was developed. In this study, We carried out Quantitative Risk Assessment with this program by using a factor of cross passage interval, warning announcement time and congestion ratio etc for 1km tunnel with natural ventilation. In the case of 250m below of cross passage interval, Risk value due to warning announcement time was a slightly changed. but if cross passage interval is more than 250m, expected fatalities in the same HRR(heat release rate) was sharp increased. As a result, Quantitative Risk Assessment program which was developed in this research project is possible to risk assessment with ventilation type, cross passage for evacuation and detection system response property etc. hereafter, this program look forward to use as a tool for road tunnel performance based design.

• 한국산학기술학회논문지
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• 제12권2호
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• pp.841-846
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• 2011

현재 우리나라 도로의 서비스 수준은 차량의 평균 통행속도를 기준으로 평가되어지고 있다. 이는 도로의 혼잡도만을 기준으로 적용한 것으로 교통안전 측면이 고려되지 않은 것이 현실이다. 합리적인 도로 설계와 운영을 위한 평가 지표라면 도로 이용자에게 영향을 미치는 제반 인자들을 보다 포괄적으로 포함할 수 있어야 한다. 본 논문에서는 교통안전과 소통측면을 총괄할 수 있는 변수로 사용자비용 개념을 적용하여 도로 평가방법을 개발하고자 한다. 또한, 본 논문에서는 이러한 도로 평가 방법을 기존의 일회성 개발 방법이 아닌 UML 기반의 사용자 중심 분석 방법을 이용하여 설계한다.

• 대한두개안면성형외과학회지
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• 제24권4호
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• pp.159-166
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• 2023

Background: Free tissue transfer is the preferred method of reconstructing head and neck defects, with a success rate of approximately 95%. Although flap failure is uncommon, it has a major impact on patient morbidity and diminishes quality of life, making it is important to investigate the causes of flap failure. Methods: This retrospective chart review analyzed patients who underwent free tissue transfer during head and neck reconstruction at a single institution between 2016 and 2021. Results: During the study period, 58 patients underwent 60 free flap procedures. Revision surgery was needed in 14 patients. Subsequent free flap surgery was performed in one patient, and three free flaps (5%) could not be salvaged. Cardiovascular disease was significantly associated with flap failure, and venous congestion (thrombosis) was the most common reason for revision surgery. Conclusion: Cardiovascular disease clearly emerged as a factor related to the failure of free flap surgery, and this issue warrants particular attention in patients for whom free tissue transfer is planned.

• 대한수의학회지
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• 제62권1호
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• pp.4.1-4.5
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• 2022

This paper describes a fatal case of pneumonia in a 14-day-old dog caused by extraintestinal pathogenic Escherichia coli (ExPEC). The necropsy showed that almost all of left lobes of the lungs had dark-red consolidation. A histopathology examination revealed moderate acute fibrino-hemorrhagic necrotizing pneumonia with intralesional bacterial colonies. Non-suppurative epicarditis, congestion in the liver, and necrosis in the white pulp of the spleen also were found. E. coli with cytotoxic necrotizing factor 1 and α-hemolysin was isolated from the lung. This case was confirmed to have fatal pneumonia caused by ExPEC that led to a systemic infection.

• 한국식품조리과학회지
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• 제27권6호
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• pp.825-838
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• 2011

The main purposes of this study were to assess coffee shop use and to identify the influence of physical environment of a coffee chop on customer behavioral intention. The survey was administered from April to May 2011, targeting twenties college students in Seoul, Gyeonggi Province. A total of 174 copies of the questionnaire were collected for the data analyses such as frequency test, descriptive analysis, chi-square analysis, reliability test, factor analysis, ANOVA, Duncan's multiple range test and multiple regression analysis using SPSS 17.0 program. The main results of this study were as follows: The number of visits was once or twice a week. Students went with their friends to the coffee shop. Most of the students answered that they visit the coffee shop at any time. The main purpose of visit was to have time to relax. The main source in choosing a coffee shop was recommendation from others. The main criterion for the selection of the coffee shop was atmosphere. Americano was a favorite drink. Coffee was drunk with a cake. Expenditure per visit was 3,000~5,000 won. The choice of the coffee shop was selected by the student. The factor analysis identified seven underlying dimensions of coffee shop physical environment perceptions (seating comfort, attractiveness, cleanliness, harmony, ambient condition, congestion, amenity) and one dimension of customer behavioral intention. Through multiple regression analyses, four determinants (attractiveness, cleanliness, amenity, ambient condition) were found to have the greatest impact on customer behavioral intention.

• 대한임상검사과학회지
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• 제43권3호
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• pp.113-119
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• 2011

This study was designed to determine the effects of larval extracts from Protaetia brevitarsis seulensis shade dried larva from Korea and China on liver tissues of hepatic injury groups. The experimental groups are divided into five groups; Normal, carbon tetrachloride single injection ($CCl_4$), Pb-CHI ($CCl_4$ + P. brevitarsis shade dried larva from China), Pb-KOR ($CCl_4$ + P. brevitarsis shade dried larva from Korea) and SIL ($CCl_4$ + 0.35% silymarin) groups. Sprague Dawley rats were oral injected with $CCl_4$ at a dose l mg/kg (20% in corn oil) for induction of liver damage for 4 weeks. Each experimental group was fed with a dose 50 mg/kg of larval extracts based on medicinal preparations from 3 weeks to 4 weeks after $CCl_4$ treatment. At the end of 4 weeks, we evaluated the serum levels of glutamate-oxaloacetate transaminase (GOT), glutamate-pyruvate transferase (GPT), alkaline phosphatase (ALP) and blood urea nitrogen (BUN) in serum and the cytokine levels of tumor necrosis factor-${\alpha}$) (TNF-${\alpha}$) and transforming growth factor-${\beta}$ (TGF-${\beta}$) in the cells isolated from spleen and liver. The histological analysis was also conducted. The $CCl_4$ injection reduced body weight, induced congestion of middle lobe and hepatocytic degeneration, resulting in disintegration of hepatic cords, and increased biochemical markers of blood related to hepatic injury. On the other hand, the Pb-CHI and Pb-KOR group decreased the levels of biochemical markers in blood and cytokine levels in spleen and liver. Especially, the Pb-KOR group facilitated the recovery of biochemical values of blood related to hepatic injury, hepatic lesions and fibrosis. Taken together, larval extract from P. brevitarsis might prevent acute hepatotoxicity and enhance the recovery of liver fibrosis and cirrhosis induced by $CCl_4$, and the ingredients could be a promising candidate for the prevention and treatment of hepatic disorders.

• 한국안전학회지
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• 제27권3호
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• pp.153-160
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• 2012

Various social problems such as traffic congestion, car accidents and environmental problems(air pollution, noises etc.) have been happening in the Seoul metropolitan area that has the car oriented traffic system providing cars continuously. Along with this, the financial burden caused by current oil price anxiety made paradigm shift from caroriented to public transportation-oriented. Its typical example is an arterial branch bus system changing(bus lane through the center of main road) started in Seoul in July, 2004. But study on safety analysis of bus lane and characteristic of accidents are not sufficient enough to now. The bus lanes are expanded to provide roads for better traffic operation and accidents between buses and pedestrians or ordinary vehicles are considered main problems. This study divided each bus route of median bus lane(bus-only lane through the center of main roads) and bus lane at roadside by intersection and collected and analysed data about influence variables of bus accidents chosen in each section. We constructed a logistic model using collected data. As a result, bus lane at roadside are used by both buses and other kinds of vehicles differently from median bus lane and showed such characteristic in accident influence. Therefore access management to factors causing conflict and improvement of operation management are required. In case of median bus lane, the more buses moving general vehicle lane and traffic volume of section were, the more accidents happened. In case that stop line of center lane is not backward, view blocking of vehicles turning left caused accidents.