• Journal of fish pathology
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• v.20 no.3
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• pp.315-325
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• 2007

Histological changes in gill and liver of eel, Anguilla japonica (average weight 96±3.6 g) were examined with formalin bath at 0~500 ppm for 1, 6 and 24 h. Hyperplasia, hypertrophy, cell fusion, desquamation and necrosis of epithelial cells at gill lamella and gill filament were observed from 6 h at 200 ppm, 1 h at 300 ppm, 1 h at 400 ppm and 1 h at 500 ppm. In the exposure of formalin 100 ppm for 24 h, epithelial cells arrangement of gill filament and gill lamella showed thinner and more regular order than the control. trophy and pyknosis of hepatocytes, congestion at sinus or central vein, degeneration of cytoplasm were observed in the liver from 24 h at 100 ppm and 200 ppm, 6 h at 300 ppm, 1 h at 400 ppm and 500 ppm. However, there were not any histological changes at liver of 100 ppm-1, 6 h, 200 ppm-1, 6 h and 300 ppm-1 h compared with the tissue of control.

• Toxicological Research
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• v.34 no.4
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• pp.325-332
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• 2018

The mechanism of the previously reported antidiabetic effect of Basella alba is unknown. This study investigated the role of B. alba aqueous leaf extract in the modulation of inflammatory cytokines and islet morphology in streptozotocin-induced diabetic rats. Forty male Wistar rats, between 8 and 10 weeks old, were randomly divided into four groups (n = 10) and administered the following treatments: Healthy control (H-c) and Diabetic control (D-c) animals received normal saline 0.5 mL/100 g body weight daily, while Healthy Treatment (H-Ba) and Diabetic Treatment (D-Ba) rats received the plant extract 200 mg/kg body weight daily. All treatments were administered by oral gavage. Diabetes was induced in D-c and D-Ba rats by a single intraperitoneal injection of streptozotocin (55 mg/kg body). The body weight and fasting blood sugar (FBS) levels were recorded every week for 4 weeks, after which the rats were euthanized and samples collected for further analysis. After the experiment, FBS level was significantly reduced (p < 0.0001) in rats in the D-Ba group, but increased (p < 0.001) in rats in the D-c group. The absolute (H-c and H-Ba vs D-c, p < 0.05) and relative (D-Ba vs H-c, p < 0.05; D-Ba vs H-Ba, p < 0.005) weights of the pancreases were significantly higher after the experiment. The rats in the D-c group had significantly higher levels of serum interleukin-$1{\beta}$ (p < 0.001 vs H-c; p < 0.05 vs H-Ba and D-Ba) and monocyte chemotactic protein-1 (p < 0.0001), but lower levels of interleukin-10 (p < 0.05) in comparison with the other groups. Histopathological examination revealed severe interstitial congestion, reduced islet area (p < 0.0001), and increased islet cell density in the D-c group compared with those in the D-Ba group. From these findings, it was concluded that the aqueous extract of B. alba stimulates the recovery of beta-islet morphology in streptozotocininduced diabetic rats by modulating the peripheral production of inflammatory cytokines.

• Journal of Korean Society of Transportation
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• v.30 no.3
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• pp.31-41
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• 2012

Due to growing interests in the distribution of traffic volume through information dissemination such as VMS and traffic broadcasting system, the research on the driver's reaction and effect of the traffic report has continued. In this study, we propose a methodology, which estimates the traffic volume of diversion and the consequential diversion rate using FTMS data and TCS data, and the estimation is based on the analysis of the national highway and IC, in which real-time FTMS and TCS data are established. We also calculate the diversion rate of actual targeted sections and analyze the changes in time and spatial diversion rate. In this study, we define a deviation (considering a deviation due to dynamic properties of traffic conditions) found when the outflow traffic volume is temporarily higher than the average outflow traffic volume on a relevant time slot after providing traffic information. The diverting volume is considered to be caused by the traffic information, and the study determines the ratio of traffic volume on highways to that of route diversion as the diversion rate. The analysis on changes in the diversion rate in accordance with the time flow, the initial change in the diversion rate on upstream IC that first acquires the report on the traffic congestion is significant. After that, the change in the diversion rate on upstream IC affects the route diversion on downstream IC with spatial and time flow, and this again leads the change in upstream IC. Thereby, we confirmed that there is a feedback-control circulation system in the route diversion.

• Fire Science and Engineering
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• v.33 no.3
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• pp.138-142
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• 2019

By securing golden time, this study analyzed the effects of an emergency vehicle priority system in Cheongju, North Chungcheong province. Until the scene of a fire is reached, severe obstacles in the street, such as traffic congestion, cars coming forward, non-cooperative vehicles etc., are significant. To solve these problems of road obstacles, it is essential to adopt an emergency vehicle priority system. From April 2017 to June 2018 (1 year and 2 months, 426 days), the dispatch time and date, fire truck moving distance and required time, traffic signal control section and pass time, and shortening time, were measured. This study selected 140 cases consisting of five heavy traffic and frequent dispatch routes out of 293 cases. The effects of the emergency vehicle priority system were excellent. Overall, it took 3 min 3 s to pass 1 km on an uncontrolled traffic signal section. On the other hand, it took 1 min 23 s to pass 1 km on the same section that was controlled. The shortening time to pass 1 km was 1 min 40 s, showing a 45.4% reduction. This means that the 15 min driving time can be reduced to 6 min and 49 s. From this result, an emergency vehicle priority system should be implemented nationwide as soon as possible.

• Journal of Nutrition and Health
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• v.1 no.3_4
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• pp.201-205
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• 1968

The authors has observed the histopathologically and histochemically on the effect of the garlic and garlic oil to the liver and kidney of rats. In order to confirm the histochemical changes of the metabolism of polysaccarides, the periodic acid Schiff reaction was applied. The 30 albino adult male rats weighing about 150 grames from the National Institute of Health were housed individualy and devide into 3 experimental groups: Group C: stock diet group Group B: stock diet-garlic group Group A: stock diet-garlic oil group Group C was fed with stock diet only through out this experimental period, Group B was fed with stock diet supplemented with garlic homogenator to be 1%, and Group A was fed with stock diet supplemented with the garlic oil to 0.05%. The garlic oil used in this experiments was extracted by author. And all rats was fed during 10 weeks. The histopathological and histochemical results were shown in each figure. According to the all results, the following concIusions were drawn. 1) In the garlic oil administrated groups, congestion of the sinusoid was subsided and the liberation of the Kupffer's cells were observed. 2) In garlic administrated groups, fatty metamorphosis in hepatic cells, and slight liberation of Kupffer's cells in sinusoidal walls were observed. Connective tissue proliferation and collagen bundle were observed. 3) The connective tissue and blood vessel wall in portal area Were reacted intensely with PAS stain. The hepatic cells Were reacted intensely with PAS stain in control group and moderately or slightly in garlic and garlic oil administrated group. 4) There were no significant differences in collecting and Henle's loops in each groups, but narrowing of lumen of the distal tubules were observed in garlic oil administrated group. 5) The basement membrane of the tubules and the connective tissues of the vessel wall in Kideny were reacted intensely with PAS stain in each groups. In control and garlic administrated groups. the brush border of the proximal tubules were reacted intensely with PAS stain, but epithelium of the Heine's loop, proximal, distal and collecting tubules were reacted moderately. In garlic oil administrated-group, there were tendency of decreasing of PAS stain in each tubules.

• Journal of KIISE:Computing Practices and Letters
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• v.14 no.4
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• pp.369-377
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• 2008

Today, Ethernet technology is rapidly developing to have a bandwidth of 10Gbps beyond 1Gbps. In such high-speed networks, the existing method that host CPU processes TCP/IP in the operating system causes numerous overheads. As a result of the overheads, user applications cannot get the enough computing power from the host CPU. To solve this problem, the TCP/IP Offload Engine(TOE) technology was emerged. TOE is a specialized NIC which processes the TCP/IP instead of the host CPU. In this paper, we implemented a high-performance, lightweight TCP/IP(HL-TCP) for the TOE and applied it to an embedded system. The HL-TCP supports existing fundamental TCP/IP functions; flow control, congestion control, retransmission, delayed ACK, processing out-of-order packets. And it was implemented to utilize Ethernet MAC's hardware features such as TCP segmentation offload(TSO), checksum offload(CSO) and interrupt coalescing. Also we eliminated the copy overhead from the host memory to the NIC memory when sending data and we implemented an efficient DMA mechanism for the TCP retransmission. The TOE using the HL-TCP has the CPU utilization of less than 6% and the bandwidth of 453Mbps.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.14 no.6
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• pp.77-90
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• 2015

An increasing number of vehicles is causing various traffic problems such as chronic congestion of highways and air pollution. Local governments have been managing traffic by constructing systems such as Intelligent Transport Systems (ITS) and Advanced Traffic Management Systems (ATMS) to relieve such problems, but construction of an infrastructure-based traffic system is insufficient in resolving chronic traffic problems. A more sophisticated system with enhanced operational management capabilities added to the existing facilities is necessary at this point. As traffic patterns of the urban traffic flow is time-specific due to the different vehicle populations throughout the time of the day, a local network-wide signal operation plan that can manage such situation-specific traffic patterns is deemed to be necessary. Therefore, this study is conducted for the purpose of establishment of a plan for contextual signal control management through signal optimization at the network level after setting the Frame Signal in accordance to the traffic patterns gathered from the short-term traffic forecast data as a means to mitigate the problems with existing standardized signal operations.

• The KIPS Transactions:PartB
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• v.11B no.5
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• pp.603-610
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• 2004

The distributed Information Retrieval System centrally controlled by mediator or meta search engine result in congestion of heavy traffic and int he problem of increment of cost for the reason of the design of complicated algorithm for central control and installation of hardware. So to figure out this problem, the way is needed that has independent retrieval functionality and can cooperate each other without dependency. In this paper, we overview a few works involved in distributed information retrieval system, then, implement algorithm and design the frame-work of distributed information retrieval system using sequential transferring method(STM) including multiple information retrieval system separated from central control. For this first of all, we present a web partition policy which devide and manage web logically and we present the sequential query processing way by means of illustration through changing numbered information retrieval system. Then, we also present 3-layered structure of framework and function and module of each layer suitable for information retrieval system. Last of ail, for effective implementation of STM algorithm we analysis module structure and present description of pseudocode of this, and show that the proposed STM algorithm works smoothly by demonstration of sequential query transfer process between servers.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.20 no.3
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• pp.1-19
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• 2021

The domastic hard shoulder running(HSR) System has been gradually expanding since its initial implementation in September 2007 with the aim of increasing capacity and resolving congestion. Hard Shoulder is used as a space for driver's visual comfort and a place for vehicles to evacuate in case of emergency, but it is replaced by a space for driving when the HSR System is implemented. Therefore, it was intended to determine the improvement effect before and after implementation of the HSR system through safety analysis and mobility analysis. The safety analysis analyzed the impact of traffic accidents by comparing HSR sections and similar sections. The mobility analysis was to determine the improvement effect by quantifying the speed and traffic volume changes before and after HSR System implementation. According to safety yanalysis, there is no effect of reducing traffic accidents when implementing the HSR System. In mobility analysis, the implementation of the HSR System significantly improved the speed of traffic during peak hours and significantly reduces slow and delay hours.

• Journal of the Korean Geographical Society
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• v.30 no.1
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• pp.35-56
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• 1995

During the last two decades, Korea has achieved remarkable economic growth. In this process the nation has become urbanized and industrialized. But we have also encountered widening regional disparity, housing shortage of larger cities, transportation congestion, environmental pollution and many other problems. Rapid increasing urbanization and continuous migration toward Seoul since the late 1960s have been one of the major concerns of government. Government has sought ways to moderate the population increase in Seoul. The regulation which include new town development near Seoul and dispersion strategies of higher education and other administration and living facilities outside of Seoul havemade a great expansion of the spatial influence of Seoul city. Seoul metropolitan reaion has evolved as the most powerful center of political and economical spaces. Generally within a metropolitan region, there exists a growing mutual interdependence economically, as well as socially between a central city and its surrounding area. Seoul metropolitan region manifests itself not only as a coherent system of urbanized regions, but also as an integral part of the daily urban system. The surrounding Gyunggi province and Seoul city become closely linked both economically and functionally, constituting true functlonai urban system. This study is primarily undertaken with the purpose of delineation of the sphere of influence of Seoul city in 1990. At the time of 1985, Seoul metropolitan region was delineated according to the result of the study which was performed by Korea Research Institute for Human Settlements. Afterward, the rapid speed of metropolitanization process with dramatic increase in mobility through the provision of wider transportation system across the Capital region have evolved, resulting in the great expansion of the spatial influence of Seoul city. So this study examines the expanded area of Seoul metropolitan regin during the period of 1985-90. In order to delineate Seoul metropolitan region, the indices of urbanization and functional linkage are selected. Variables included in the measurement of the urbanization level are agricultural structure, population characteristics, manufacturing and service industries, and cultural aspects such as newspaper circulation, the ratio of car ownership and piped water supply. Variables included in the measurement of functional linkage are commuting, shopping pattern, centralized service such as medical facilities and trade of agricultural products. The standardization method and factor analysis are employed in making the delineation of Seoul metropolitan region. According to the result of this study, 2 cities, 8 Eups and 46 Myuns are included Seoul metropolitan region in 1990. If we compare this delineated area in 1990 to that of 1985, we can find the distinctive pattern of expanded axes according to the main transportation routes such as Seoul-Suweon, Seoul-Gwangju, Seoul-Incheon. In 199O, all the Gyunggi province, except a few Myuns located at the north and northwest part of Gyunggi province, are included in Seoul metropolitan region. Furthermore, this study attempts to the analysis of regional structure of Seoul metropolitan region according to the functional characteristics of each city and Gun. Variables included in this analysis are the new residential function, manufacturing function, service function, education and infermation function, public facility function and agricultural function. Factor analysis and cluster analysis are employed in making regionalization. Seoul metropolitan reaion is subdivided into four subregions which reflect different functional specialization. The first group is the specialized region of newly formed residential function. The second group is the specialized reaion of manufacturing function. The third group is the specialized region of service function. And the fourth group has little specialized in terms of manufacturing, service, and residential function. But this region has some potentiality of development when Seoul metropolitan region grow continuously. Seoul metropolitan region accounted for 43% of national population, despite 11.8% of national land size in 1990. Although Seoul metropolitan region enjoys important agglomeration economies, it also has huge social cost in the form of transportation congestion, housing shortage, rapid increase of land value, environment pollution, and etc. Efficient metropolitan plan making is a vital element in promoting Seoul's economic development and providing high quality living environment at low cost. In the light of the result of this study, the outer ring of Seoul metropolitan region, especially northeastern part, are underdeveloped compared to overdeveloped southwestern area. It is needed to develop the guidelines for the implement of the growth control and management plan, inducing more balanced development for whole Seoul metropolitan reaion.