• 제목/요약/키워드: confounding factors

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서울 지역에서 분진에 대한 장기 추세 연구 (Long term trend for particular matters in Seoul)

  • 박혜련;최기헌
    • Journal of the Korean Data and Information Science Society
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    • 제20권5호
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    • pp.765-777
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    • 2009
  • 본 연구에서는 대기오염물질 중에서 주목을 받고 있는 분진 직경이 10마이크로미터 (micrometer) 이내의 것을 대상으로 실제로 증가하는지 감소하는지를 알아보기 위하여 교락 요인을 제외한 분진을 대상으로의 순수한 장기 추세를 연구하였다. 자료는 1996년에서 2000년까지 서울시의 기상 변수들 (최대기온, 평균습도, 최대풍속, 일사량)과 27지점에서 얻은 분진 직경이 10마이크로미터 이내의 것을 이용한다. 이 자료를 이용하여 분진과 비선형 관계를 보이는 기상 변수들의 회귀 스플라인을 이용하여 계절성을 통제한 일반화 부가모형을 세웠다. 그 결과 증가가 아닌 감소하는 순수 장기 추세를 얻을 수 있었다.

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Is Caffeine Intake Associated With Urinary Incontinence in Japanese Adults?

  • Hirayama, Fumi;Lee, Andy H.
    • Journal of Preventive Medicine and Public Health
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    • 제45권3호
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    • pp.204-208
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    • 2012
  • Objectives: To investigate whether caffeine intake is associated with urinary incontinence (UI) among Japanese adults. Methods: A total of 683 men and 298 women aged 40 to 75 years were recruited from the community in middle and southern Japan. A validated food frequency questionnaire was administered face-to-face to obtain information on dietary intake and habitual beverage consumption. Urinary incontinence status was ascertained using the International Consultation on Incontinence Questionnaire-Short Form. Results: Mean daily caffeine intake was found to be similar between incontinent subjects (men 120 mg, women 94 mg) and others without the condition (men 106 mg, women 103 mg), $p$=0.33 for men and $p$=0.44 for women. The slight increases in risk of UI at the highest level of caffeine intake were not significant after adjusting for confounding factors. The adjusted odds ratios (95% confidence interval) were 1.36 (0.65 to 2.88) and 1.12 (0.57 to 2.22) for men and women, respectively. Conclusions: No association was evident between caffeine intake and UI in middle-aged and older Japanese adults. Further studies are required to confirm the effect of caffeine in the prevention of UI.

When Work is Related to Disease, What Establishes Evidence for a Causal Relation?

  • Verbeek, Jos
    • Safety and Health at Work
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    • 제3권2호
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    • pp.110-116
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    • 2012
  • Establishing a causal relationship between factors at work and disease is difficult for occupational physicians and researchers. This paper seeks to provide arguments for the judgement of evidence of causality in observational studies that relate work factors to disease. I derived criteria for the judgement of evidence of causality from the following sources: the criteria list of Hill, the approach by Rothman, the methods used by International Agency for Research on Cancer (IARC), and methods used by epidemiologists. The criteria are applied to two cases of putative occupational diseases; breast cancer caused by shift work and aerotoxic syndrome. Only three of the Hill criteria can be applied to an actual study. Rothman stresses the importance of confounding and alternative explanations than the putative cause. IARC closely follows Hill, but they also incorporate other than epidemiological evidence. Applied to shift work and breast cancer, these results have found moderate evidence for a causal relationship, but applied to the aerotoxic syndrome, there is an absence of evidence of causality. There are no ready to use algorithms for judgement of evidence of causality. Criteria from different sources lead to similar results and can make a conclusion of causality more or less likely.

Effects of self-ligating brackets and other factors influencing orthodontic treatment outcomes: A prospective cohort study

  • Jung, Min-Ho
    • 대한치과교정학회지
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    • 제51권6호
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    • pp.397-406
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    • 2021
  • Objective: The purpose of this study was to evaluate the effects of self-ligating brackets (SBs) and other factors that influence orthodontic treatment outcomes. Methods: This two-armed cohort study included consecutively treated patients in a private practice. The patients were asked to choose between SBs and conventional brackets (CBs); if any patient did not have a preference, he or she was randomly allocated to the CB or SB group. All patients were treated using an identical archwire sequence. Evaluated parameters were as follows: treatment duration, number of bracket failures, poor oral hygiene, poor elastic wear, extraction, use of orthodontic mini-implants (OMI), OMI failure, American Board of Orthodontics (ABO) Discrepancy Index (DI), arch length discrepancy, and ABO Cast-Radiograph Evaluation (CRE) score. Stepwise regression analysis was performed to generate the equation for prediction of the CRE. Results: The final sample comprised 134 patients with an average age of 22.73 years. The average DI, CRE, and treatment duration were 21.81, 14.25, and 28.63 months, respectively. Analysis of covariance showed a significant difference in CRE between the CB and SB groups after adjusting for the effects of confounding variables. Stepwise regression analysis using four variables, namely extraction, SB use, poor elastic wear, and additional appliance use, could explain only 25.2% of the variance in the CRE. Conclusions: Although the CRE was significantly better for CBs than for SBs, the clinical significance of this result seems to be limited. Extraction, SB use, poor elastic wear, and additional appliance use may have significant effects on treatment outcomes.

청소년의 건강관련 특성 및 구강건강관련 특성이 치아우식에 미치는 영향 (Effects of Adolescent and Oral Health-Related Characteristics on Dental Caries)

  • 이미옥;이은주
    • 보건의료산업학회지
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    • 제12권2호
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    • pp.101-112
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    • 2018
  • Objectives : This study examined the influence of socio-demographic, health-related, and oral health-related characteristics on adolescent DMFTs. Methods : The subjects in this study were 1,129 adolescents selected from the 6th national health and nutrition examination survey data. To determine the factors influencing dental caries, a regression analysis using a complex-sample generalized linear model was conducted after adjusting for confounding factors. Results : DMFTs were smaller among boys than girls, and smaller in the "13-15 age group" than in the "16-18 age group." In terms of household income, DMFTs were larger in the "lower," "lower-middle," and "upper-middle" income brackets than in the "upper" income bracket. DMFTs were smaller among adolescents with a history of smoking than those who had never smoked. Conclusions : In order to improve the oral health of adolescents, oral health-promotion programs should be provided for girls, high school students, students from low-income families, smokers, and those who consider themselves to have poor oral health.

Outcome Assessment of Endodontic Treatment of Mandibular Second Molars with C-shaped Canals in Elderly Patients

  • Go, Yu-Ra;Kim, Mi-Yeon;Kim, Sun-Ho;Kim, Jeong-Hee;Kim, Ran-Ah
    • Journal of Korean Dental Science
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    • 제14권2호
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    • pp.61-68
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    • 2021
  • Purpose: The aim of this study was to investigate the outcomes of endodontic treatment of mandibular second molar with C-shaped canal in elderly patients and related factors affecting the survival of the tooth. Materials and Methods: From 2010 to 2015, the survival rate following endodontic treatment was evaluated in elderly patients over 60 years who visited the Veterans Health Service Medical Center for endodontic treatment. The presence of C-shaped canals was confirmed using clinical records and radiographic features. Patient's age, sex, systemic diseases, tooth location, vitality, signs and symptoms, fractures, caries, apical radiolucency, canal shaping methods, sealer leakage, filling voids, and restoration of prosthesis were included in the analyses as confounding variables. The survival rate of teeth was analyzed using Kaplan-Meire analysis and the relationship between the survival rate and variables was analyzed using Simple and Multiple Cox regression analysis. Result: In total, 107 teeth in elderly patients had C-shaped canal. The survival rate of teeth that received endodontic treatment was 63.70%. None of the factors investigated significantly influenced the survival rate (P>0.05). Conclusion: In elderly patients with C-shaped canal, the survival rate after root canal treatment was not significantly different from that of other mandibular molars.

Association between sugar-sweetened beverage consumption and depression and suicidal ideation among Korean adults: a cross-sectional study from the 2014 and 2016 Korean National Health and Nutrition Examination Survey (KNHANES)

  • Kim, Jiyeong;Hong, Changbin;Lee, Gyeongsil
    • Nutrition Research and Practice
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    • 제16권2호
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    • pp.194-204
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    • 2022
  • BACKGROUND/OBJECTIVES: Sugar-sweetened beverages (SSBs) are regarded as modifiable risk factors for mental health in several populations. Although the consumption of SSBs is steadily increasing in Korea, there is scant evidence regarding the impact of SSB consumption on depression and suicidal ideation. The aim of this study was to investigate the association of SSB consumption with depression and suicidal ideation among adults in Korea. SUBJECTS/METHODS: We used the data for 5,465 participants (2,170 men and 3,295 women) aged ≥ 20 years from the 2014 and 2016 Korea National Health and Nutrition Examination Survey. The subjects were divided into four groups according to SSB consumption using a food frequency questionnaire. Logistic regression analyses were conducted to examine the association of SSB consumption with depression and suicidal ideation, adjusting for sociodemographic, health behavior, and dietary variables. RESULTS: Participants consuming ≥ 1 SSB/day had a significantly higher risk of depression (odds ratio [OR], 1.54; 95% confidence interval [CI], 1.08-2.18; P < 0.001) and suicidal ideation (OR, 2.20; 95% CI, 1.13-4.28; P < 0.001) compared with those in the non-SSB group after adjusting for potential confounding factors. CONCLUSIONS: Our results suggest that SSB consumption is positively associated with depression and suicidal ideation in Korean adults.

Relationships of Colorectal Cancer with Dietary Factors and Public Health Indicators: an Ecological Study

  • Abbastabar, Hedayat;Roustazadeh, Abazar;Alizadeh, Ali;Hamidifard, Parvin;Valipour, Mehrdad;Valipour, Ali Asghar
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권9호
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    • pp.3991-3995
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    • 2015
  • Background: Colorectal cancer (CRC) is the third most common cancer in Iranian women and fifth in men. The aims of this study were to investigate the relation of dietary factors and public health indicators to its development. Materials and Methods: The required information (2001-2006) about risk factors was obtained from the Non-Communicable Disease Surveillance Centre (NCDSC) of Iran. Risk factor data (RFD) from 89,404 individuals (15-64 years old) were gathered by questionnaire and laboratory examinations through a cross sectional study in all provinces by systematic clustering sampling method. CRC incidence segregated by age and gender was obtained from Cancer Registry Ministry of Health (CRMH) of Iran. First, correlation coefficients were used for data analysis and then multiple regression analysis was performed to control for confounding factors. Results: Colorectal cancer incidence showed a positive relationship with diabetes mellitus, hypertension, lacking or low physical activity, high education, high intake of dairy products, and non-consumption of vegetables and fruits. Conclusions: We concluded that many dietary factors and public health indicators have positive relationships with CRC and might therefore be targets of preliminary prevention. However, since this is an ecological study limited by potential ecological fallacy the results must be interpreted with caution.

강원도 춘천 지역 개의 비만 유병률과 위험요인에 대한 단면연구 (A Cross-sectional Study on the Prevalence of Canine Obesity and Associated Risk Factors in Chuncheon, Kangwon Province)

  • 박선일
    • 한국임상수의학회지
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    • 제31권1호
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    • pp.31-35
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    • 2014
  • As with humans, overweight or obesity is a major health concern in the companion animal population. A cross-sectional questionnaire-based survey of dog owners attending primary small animal veterinary practices from different areas in Chuncheon, Kangwon province, Korea was undertaken to explore the relationships between socioeconomic and other relevant risk factors associated with canine obesity. In addition, the author was to estimate the prevalence of obesity compared to published literatures for dogs. Owners were asked about dog age, neuter status, feeding habits, dog exercise, household income and owner age. The body condition score (BCS) of the dogs was also assessed. Multivariable binary logistic regression was used to assess the association between BCS and potential risk factors controlling for confounding variables, using odds ratios (OR), 95% confidence intervals (CIs). A total of 275 dogs (136 males and 139 females) aged 1-12 years (mean age $5.6{\pm}3.7$ years) were surveyed in 2013. Of these, 46.9% of dogs (n = 129) were classed as an ideal body shape (BCS = 3), 30.9% (n = 85) were overweight (BCS = 4), 8.4% (n = 23) were obese (BCS = 5) and 13.8% (n = 38) were underweight (BCS = 1 or 2). Neutered males and spayed females had the highest prevalence of obesity (43.4% and 33.9%); intact females had the lowest prevalence of obesity (31.6%). In univariable model, risk factors associated with canine obesity are multifactorial and include owner income, owner age, age of dog, neuter status, frequency of feeding per day, frequency of snacks and consultation with veterinarian on dog's weight. In final multivariable logistic regression model, dogs whose owners reported no consultation with veterinarians for weight management were significantly more likely to be obesity than ideal (OR = 7.6, 95% CI, 4.2-13.8; p < 0.0001). This study showed a high prevalence of obesity in domestic companion dogs. Since this was a cross-sectional study with small samples, the association of canine obesity with risk factors warrants more research. To the author's best knowledge, this is the first Korean study on dog body condition and obesity.

Oral Cancer Awareness of the General Public in Gorakhpur City, India

  • Agrawal, Mamta;Pandey, Sushma;Jain, Shikha;Maitin, Shipra
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권10호
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    • pp.5195-5199
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    • 2012
  • Objectives: Global cancer statistical data show that India has one of the highest incidence rates of oral cancer worldwide. Early detection is extremely important as it results in lower morbidity and death rates. The present study was undertaken to assess awareness of oral cancer and knowledge of its early signs and risk factors in the general public of the semi-urban Gorakhpur area of Uttar Pradesh (India). It was also intended to educate the same population for early detection by increasing their ability to recognize signs and risk factors. Method: A questionnaire-based household survey was conducted over a period of one month in different parts of Gorakhpur district, a region where tobacco use is apparently very high. A total of 2,093 persons participated in the survey. The collected data were analyzed using SPSS software to assess and associate oral cancer awareness with the prevalence, and abstract risk factors, as well as other confounding variables. Results: The general awareness, knowledge of signs and risk factors of oral cancer were found to be proportionate to the literacy level with the highest rate of awareness being among high school and graduates and lowest among illiterates. It was also observed that on most of these dimensions the younger age groups (<30 years) were significantly more knowledgeable. Conclusion: Overall, the awareness of oral cancer in the high-risk population of Gorakhpur was not satisfactory, pointing to a need for further dissemination of information on this issue and its associated risks. This is especially important for the youngsters, as this may possibly help them keep away from the deleterious habit of tobacco indulgence in any form. If necessary risk factor cessation counselling should be provided.