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Surgical Treatment of the Esophageal Diverticula (식도게실의 외과적 치료)

  • 이계영
    • Journal of Chest Surgery
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    • v.25 no.12
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    • pp.1537-1541
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    • 1992
  • Eleven patients with esophageal diverticulum were operated on between August 1982 and August 1992 at the Department of Thoracic and Cardiovascular Surgery of Chonnam National University Hospital have been studied. 9 patients were male and 2 were famale and the age distribution was between 20 and 55 years. Various subjective symptoms were noticed preoperatively. Diagnosis was confirmed by esophagography. The types of esophageal diverticulum were traction type in 6 cases and pulsion type in 5 cases. There were nine cases of midesophageal diverticula, 1 cases of upper-thoracic esophageal diverticulum and 1 cases of epiphrenic diverticulum. Diverticulectomy alone in 10 cases and diverticulopexy was performed in 1 case. Fistulectomy in 5 cases, lobectomy in 1 case, segmentectomy in 1 case, and Eloesser`s procedure in 1 case were performed with associated procedures. There were no death or morbidity and all patients have achieved marked improvement of symptoms except three patients who had a concomitant mucoepidermoid tumor, had a complicated postoperative pyothorax, and had a postoperative recurrence of midesophageal diverticulum. Recurrence of symptoms were not noticed during follow up except 1 recurrence of diverticulum confirmed by esophagogram.

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Wrapping of an Ascending Aortic Aneurysm with the Multiple Boot-Straps Technique in a Patient Undergoing Off-Pump Coronary Artery Bypass Grafting

  • Na, Kwon Joong;Kim, Jun Sung;Park, Kay-Hyun;Lim, Cheong
    • Journal of Chest Surgery
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    • v.48 no.3
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    • pp.206-209
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    • 2015
  • Ascending aortic aneurysms are usually treated with graft replacement under cardiopulmonary bypass. However, if a candidate for off-pump coronary artery bypass grafting has an enlarged ascending aorta, surgeons may consider wrapping it without cardiopulmonary bypass. Here, we report a 78-year-old female who underwent successful wrapping of the ascending aorta concomitant with off-pump coronary artery bypass grafting, using a new wrapping technique that involves multiple bootstraps.

c-Cbl Acts as an E3 Ligase Against DDA3 for Spindle Dynamics and Centriole Duplication during Mitosis

  • Gwon, Dasom;Hong, Jihee;Jang, Chang-Young
    • Molecules and Cells
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    • v.42 no.12
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    • pp.840-849
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    • 2019
  • The spatiotemporal mitotic processes are controlled qualitatively by phosphorylation and qualitatively by ubiquitination. Although the SKP1-CUL1-F-box protein (SCF) complex and the anaphase-promoting complex/cyclosome (APC/C) mainly mediate ubiquitin-dependent proteolysis of mitotic regulators, the E3 ligase for a large portion of mitotic proteins has yet to be identified. Here, we report c-Cbl as an E3 ligase that degrades DDA3, a protein involved in spindle dynamics. Depletion of c-Cbl led to increased DDA3 protein levels, resulting in increased recruitment of Kif2a to the mitotic spindle, a concomitant reduction in spindle formation, and chromosome alignment defects. Furthermore, c-Cbl depletion induced centrosome over-duplication and centriole amplification. Therefore, we concluded that c-Cbl controls spindle dynamics and centriole duplication through its E3 ligase activity against DDA3.

흉부외상에 의한 하행흉부대동맥파열 (수술 치험 1예 보고)

  • Chae, Hurn;Rho, Joon-Ryang
    • Journal of Chest Surgery
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    • v.13 no.1
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    • pp.72-76
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    • 1980
  • A successful repair of transected descending thoracic aorta was performed in a 44-year-old man. The patient had once been hospitalized in a local clinic for 7 days after a steering wheel injury. Dealing with right Colle`s fracture, he was transferred to this hospital to rule out aortic injury. On admission, a chest PA film and concomitant aortogram revealed an aneurysm of the descending thoracic aorta just distal to the origin of the left subclavian artery measuring 6 cm in diameter and 8 cm in length. He underwent urgent thoracotomy and the injured part of the aorta was replaced with a woven Dacron graft utilizing a Gott`s heparinized aortic shunt. The postoperative course was very smooth except hoarseness and left phrenic nerve palsy due to a blind clamping of the proximal aorta during the operation.

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Marfan's syndrome associated with ascending aorta aneurysm and aortic regurgitation (Report of 8 cases) (Marfan 증후군에 동반된 상행대동맥류와 대동맥판 폐쇄부전증의 외과적 치료)

  • Choi, Jun-Young;Ahn, Hyuk;Rho, Joon-Ryang
    • Journal of Chest Surgery
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    • v.19 no.3
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    • pp.500-505
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    • 1986
  • Eight patients received operation for ascending aortic aneurysm and aortic regurgitation associated with Marfan`s syndrome from January 1984 to July 1986 at Seoul National University Hospital. The patients` age ranged from 29 to 51 years [mean 37.3 years]. Five patients were male and three were female. All of them showed some stigmata of skeletal system in Marfan`s syndrome. Three patients had dissecting aneurysm and five patients had fusiform aneurysm of ascending aorta. Two patients had concomitant fusiform aneurysm of abdominal aorta. All patients showed aortic regurgitation of grade III to IV. One patient received insertion of intraluminal ringed graft and resuspension of aortic valve, and seven patients received modified Bentall operation [Carol`s method]. There was no hospital death and all showed functional improvement in the 7.4 patient-years follow-up period.

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Inclusion Body Myositis : Clinical Features and Electrophysiological Findings (봉입체 근염 : 임상과 전기생리학 소견)

  • Kim, Kwang-Kuk
    • Annals of Clinical Neurophysiology
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    • v.8 no.1
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    • pp.16-22
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    • 2006
  • Sporadic inclusion body myositis (s-IBM) is an aquired slowly progressive inflammatory myopathy with unknown etiology. Although light microscopic abnormalities and characteristic histopathology on muscle biopsy distinguishes from other inflammatory myopathies, vacuolated muscle fibers, intracellular amyloid deposits or tubulofilaments in electromicroscopic findings are not definite in some patients. This review shows the prominently involved muscles in s-IBM and specific or nonspecific electrophysiologic manifestations from reported data for helping the diagnosis of definite-or probable-IBM patients. In lower limbs, the quadriceps is predominantly involved, as is iliopsoas, and tibialis anterior is common. In the upper limbs, the greatest weakness is in forearm finger flexors. Finger extensors, biceps and triceps also are moderately to prominently involved. The majority of patients demonstrate polyphasic MUAPs that are short in duration. An additional striking feature is the concomitant documentation of long-duration, large-amplitude, polyphasic MUAPs. In spite of the frequent mixed myopathic-neurogenic electromyographic findings of IBM, just like that of chronic myositis, asymmetric, slowly progressive weakness of flexor digitorum profundus or quadriceps femoris muscles after age of 50 is very necessary condition for the diagnosis of IBM.

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PECVD of Blanket $TiSi_2$ on Oxide Patterned Wafers (산화막 패턴 웨이퍼 위에 플라즈마 화학증착법을 이용한 균일 $TiSi_2$ 박막형성에 관한 연구)

  • Lee, Jaegab
    • Journal of the Korean Vacuum Society
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    • v.1 no.1
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    • pp.153-161
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    • 1992
  • A plasma has been used in a high vaccum, cold wall reactor for low temperature deposition of C54 TiSi2 and for in-situ surface cleaning prior to silicide deposition. SiH4 and TiCl4 were used as the silicon and titanium sources, respectively. The deposited films had low resistivities in the range of 15~25 uohm-cm. The investigation of the experimental variables' effects on the growth of silicide and its concomitant silicon consumption revealed that and were the dominant species for silicide formation and the primary factors in silicon consumption were gas composition ratio and temperature. Increasing silane flow rate from 6 to 9 sccm decreased silicon consumption from 1500 A/min to less than 30 A/min. Furthermore, decreasing the temperature from 650 to $590^{\circ}C$ achieved blanket silicide deposition with no silicon consumption. A kinetic model of silicon consumption is proposed to understand the fundamental mechanism responsible for the dependence of silicon consumption on SiH4 flow rate.

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A Study on the Modification and Development of Curriculum for the Department of Food and Nutrition in Junior College (전문대학 식품영양과 교육과정의 수정 개발에 관한 연구)

  • Nam, Gung-Seok;So, Myeong-Hwan;Yun, Seong-Sik
    • The Korean Journal of Food And Nutrition
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    • v.2 no.1
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    • pp.45-60
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    • 1989
  • According as the economic growth and the development of highly industrialized society have improved the nation's standard of living, a great change in recognition of public health has occurred and also brought about a concomitant change in the roles and responsibilities of nutritionists. Consequently, the curriculum of Junior Colleges is required to be revised so as to provide substantial education through which the acquisition of necessary professional knowledge and technique as intermediate technicians and the efficient training can be achieved. On the basis of the survey and analysis of the current curriculum and of the functional structures of nutritionists, this study made an attempt to frame a model curriculum that may provide effective education and training and help to establish a desirable curriculum of Junior Colleges.

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Open Scapulothoracic Dissociation - Case report - (개방성 견갑-흉부 해리 증례보고)

  • Seo Sung-Woo;Jung Hyo-Sub;Moon Jun-Gyu
    • Clinics in Shoulder and Elbow
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    • v.8 no.2
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    • pp.187-191
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    • 2005
  • Traumatic scapulothoracic dissocation is a rare upper extremity injury caused by massive traction or blunt trauma. Most cases are associated with a large spectrum of concomitant injuries, including severe musculoskeletal injuries and neurovascular injuries around the shoulder. But, it occurs without damaging overlying skin as a closed injury rather than an open injury. We present a case of open scapulothoracic dissociation and describe clinical features with literature review.

PARTIAL-THICKNESS ROTATOR CUFF TEARS UPDATE PATHOGENESIS, DIAGNOSIS AND TREATMENT

  • Fukuda Hiroaki;Hamada Kazutoshi;Nakajima Tomotaka;Kobayashi Kunihiko;Uchiyama Yoshiyasu
    • The Academic Congress of Korean Shoulder and Elbow Society
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    • 2001.03a
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    • pp.91-92
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    • 2001
  • 1. Partial cuff tears are common and incapacitate active people in the 5th to 6th decades. 2. The pathogenesis appears multifactorial. 3. The pain is proportional to the degree of concomitant subacromial bursitis, not to the size of the cuff tear. 4. The diagnosis is made by several imagings, arthroscopy and/or trial tenotomy. 5. The spontaneous healing is unlikely and progression to complete tears is frequent. 6. The intratendinous extension poses therapeutic problem but satisfactory results are obtained by open surgery in approximately $90\% of cases.

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