• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.329.2-330
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• 2002

This study was intended to establish test methods equivalent to those of "Interferon alfa-2 concentrated solution" monograph in European Pharmacophoeia(EP). Two recombinant interferon alfa concentrated solutions manufactured in Korea were tested according to the monograph of EP. Tests of identification(biological activity. isoelectric focusing. SDS-PAGE under reducing condition, peptide mapping). related proteins. impurities of moducular masses differing from that of interferon alfa-2(SDS-PAGE under reducing and non-reducing condition). bacterial endotoxin, protein, potency, host-cell-derrved proteins. and host-cell-derived DNA were performed in the laboratories of manufacrues and division of biotechnology. KFDA. The results of this study showed that specitications of interfenon alfa concentrated solutions manufactured in Korea were within the aceptance criteria of EP. Based on the study. specitications and test methods for interferon alfa concentrated solution can be established according to the monograph of EP suggesting the revision of Minimum requirements for biological products

• International Journal of Naval Architecture and Ocean Engineering
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• 제9권4호
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• pp.404-417
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• 2017

The present study numerically analyzed the dynamic behavior of 3D framed structures subject to impulsive slamming forces by violent breaking waves. The structures were modeled using multiple lumped masses for the vertical projections of each member, and the slamming forces from the breaking waves were concentrated on these lumped masses. A numerical algorithm was developed to properly incorporate the slamming forces into a dynamic analysis to numerically determine the structural responses. Then, the validity of the numerical analysis was verified using the results of an existing hydraulic experiment. The numerical and experimental results for various model structures were generally in good agreement. The uncertainties concerning the properties of the breaking waves used in the verification are also discussed here.

• 대한기계학회논문집
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• 제11권1호
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• pp.124-131
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• 1987

본 논문에서는 비보존 문제중 하나 혹은 두개의 집중질량을 갖는 외팔보가 주 기적인 종동력을 받는 경우에 대해 외력의 상수항, 외력의 주기항, 질량비 및 집중질 량의 위치와 같은 계의 매개변수를 변화에 따른 불안정영역을 해석하고, 이에 따른 실 험을 하여 이론과 비교하였다.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2002년도 추계학술대회논문집
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• pp.982-987
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• 2002

Recently, as size of building structure becomes larger, mat area of building structure is supported on Inhomogeneous foundation. The equipment machineries in building are mostly on basement story. The slab of the lowest basement story with equipment machineries is considered as plate supported on foundation with concentrated masses. In this paper, vibration analysis of rectangular thin plate is done by use of rectangular finite element with 4 nodes. The solution of this paper are compared with existing solution and natural frequencies of thin plates, with concented mass, on inhomogeneous Pasternak foundation are calculated

• 한국음향학회지
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• 제8권1호
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• pp.13-22
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• 1989

본 연구에서는 음역의 변화를 위해 현재 사용중인 방법 대신 피아노 현에 집중질량을 달아, 피아노 현의 진동특성 및 음색에 관해 분석하였다. 이론적 해석은, 현의 질량을 등분화 하여 다자유도계의 스프링-질량 시스템으로 변환시켜 Holzer 방법으로 해석한 불연속계와, 모우드 합 방법과 라플라스 변환방법을 이용한 연속계로 해석하였으며 실험적 해석은 업라이트 피아노의 현에 집중질량을 부착시켜 수행하였다.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2011년도 춘계학술대회 초록집
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• pp.58.1-58.1
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• 2011

In this paper, the purpose is a study on structural analysis for offshore wind turbine using commercial code. Because offshore wind turbine is subjected to great wind and wave force, it is necessary to analyse the dynamics and minimize the response of wind turbine. The offshore wind turbine tower is modelled as a single degree of freedom and multi degree of freedom structure. It is assumed that the blades, nacelle are composed of concentrated masses.

• 대한원격탐사학회지
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• 제33권1호
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• pp.97-109
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• 2017

Green tides that developed along the coast of China in 2015 were detected and tracked using vegetation indices from GOCI and Landsat images. Green tides first appeared near the Jiangsu Province on May 14 before increasing in size and number and moving northward to the Shandong Peninsula in mid-June. Typhoon Cham-hom passed through the Yellow Sea on July 12, significantly decreasing the algal population. An algae patch moved east toward Korea and on June 18 and July 4, several masses were found between the southwestern shores of Korea and Jeju Island. The floating masses found in Korean waters were concentrated at the boundary of the open sea and the Jindo cold pool, a phenomenon also observed at the boundary of coastal and offshore waters in China. Sea surface temperatures, derived from NOAA SST data, were found to play a role in generation of the green tides.

• Structural Engineering and Mechanics
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• 제57권6호
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• pp.989-1014
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• 2016

This paper deals with the analysis of the natural frequencies, mode shapes of an axially loaded beam system carrying ends consisting of non-concentrated tip masses and three spring-two mass sub-systems. The influence of system design and sub-system parameters on the combined system characteristics is the major part of this investigation. The effect of material properties, rotary inertia and shear deformation of the beam system is included. The end masses are elastically supported against rotation and translation at an offset point from the point of attachment. Sub-systems are attached to center of gravity eccentric points out of the beam span. The boundary conditions of the ordinary differential equation governing the lateral deflections and slope due to bending of the beam system including developed shear force frequency dependent terms, due to the sub.system suspension, have been formulated. Exact formulae for the modal frequencies and the modal shapes have been derived. Based on these formulae, detailed parametric studies are carried out. The geometrical and mechanical parameters of the system under study have been presented in non-dimensional analysis. The applied mathematical model is presented to cover wide range of mechanical, naval and structural engineering applications.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 1994년도 가을 학술발표회 논문집
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• pp.231-234
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• 1994

Concentrated stresses due to the tunnel excavation easily cause failure around opening in the soft rock mass layer. Thus, while excavatng tunnel in the soft rock mass layerm it is very important to predict the possibility of failure or yielding zones around tunnel boundary. There are two typical methods to predict these; 1) the analysis of field monioring data and 2) numerical analysis. In this study, it was attempted to describe the time-dependent or progressive rock mass manner due to the continuous failure and fracturing caused by surrounding underground openings using the second method. In order to apply the effects of progressive failure underground, an iterative technique was used with the Hoek and Brown rock mass failure theory. By developing and simulating, three different shapes of twin tunnels, this research simulated and estimated the proper size of critical pillar width between tunnels, distributed stresses on the tunnel sides, and convergences of tunnel crowns. Moreover, results out progressive failure technique based on the Hoek and Brown theory were compared with the results out of Mohr-Coulomb theory.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2002년도 생물공학의 동향 (X)
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• pp.188-191
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• 2002

A glucan and a fructan producing enzymes from Leuconostoc mesenteroides NRRL B-1149 were prepared and concentrated from the cu1ture of 1.5% sucrose using polysulfone ultrafiltration hollow fiber in the presence of 0.1% (w/v) Tween 80, 1 mM $CaCl_2$, and 0.02% $NaN_3$. The molecular masses of the enzymes were estimated to be about 213.6 kDa and 180 kDa, respectively, based on the PAS staining for the glucosyltransferase and Mukasa method for fructosyltransferase. Polymers produced by the enzymes showed different solubility; an insoluble glucan and a soluble fructan. The linkages of polymers were determined by methylation using Hakomori reagent and following acid hydrolysis. The glucan was composed of ${\alpha}$-1,6 and 1,3 linkages and the fructan showed similar linkage data of levan.