• 생물정신의학
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• 제6권2호
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• pp.240-245
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• 1999

Object : This study was designed to evaluate the effects of olanzapine on the schedule-induced polydipsia(SIP) which is one of animal model of obsessive-compulsive disorder in rats. We administered olanzapine as a serotonin and dopamine blocking agent, fluoxetine as a selective serotonin reuptake inhibitor, and haloperidol for the dopamine antagonist to rats which showed schedule-induced polydipsic behavior. Methods : Spraque-Dawley rats weighing 200-250gm were individually housed and maintained and allowed free access to water. The rats were placed on a restricted diet. To induce polydipsia, rats were placed in the cage where a pellet dispenser automatically dispensed 90mg pellets on a fixed-time 60 seconds(FT-60s) feeding schedule over 150 minute test session per day. Water was available at all times in the cage. After 4 weeks of daily exposure to the FT 60s feeding schedule, experimental rats met a predetermined criterion for polydipsic behavior(greater than 3 times of water per session on average). 5 groups of rats were administered olanzapine(3mg/kg, i.p), olanzapine(10mg/kg, i.p), fluoxetine(5mg/kg, i.p.), haloperidol(0.1mg/kg, i.p.), and vehicle(1cc/kg, i.p.) for 3 weeks. The rats were tested once a week to access schedule induced polydipsic behavior. Water bottles were weighed before and after the 150-minute test session. The chronic effects of administration of experimental drugs on schedule induced polydipsic behavior were analyzed with ANOVA and Scheffe test as a posthoc comparison. In order to measure water consumption in non-polydipsic food-deprived rats, a separate group of rats(N=8) were individually housed and given a single bolus(14.5gm) of food per day which maintained them at their average body weight. Results and Conclusion : The results were as follows ; 1) After 4 weeks of scheduled feeding procedure, the experimental group showed significant differences than the bolus control in the amount of water consumption as compared with their average water intakes for 4 weeks. At the same periods, there were no differences between the experimental group and the bolus control in the body weight. 2) The fluoxetine group showed significant decrease in the amount of water intake over the 3 weeks of drug treatment as compared with their average amount of polydipsic water intakes. The olanzapine 3mg group showed significant decrease in the amount of water intake at 3rd weeks of drug treatment as compared with their average amount of polydipsic water intakes. The olanzapine 10mg group showed significant decrease in the amount of water intake at 2nd and 3rd weeks of drug treatment as compared with their average amount of polydipsic water intakes. However, the haloperidol group and the vehicle control group showed no changes of amounts of water intake for 3 weeks of treatment as compared with their average amount of polydipsic water intakes. 3) The fluoxetine group showed significantly lower amounts of water intake than the haloperidol group at 2nd weeks of drug treatment. And also the fluoxetine group showed significantly lower amounts of water intake than the haloperidol group and the vehicle control at 3rd weeks of drug treatment. The olanzapine 3mg group and the olanzapine 10mg group showed significantly lower amounts of water intake than the haloperidol group and the vehicle control at 3rd weeks of drug treatment. Above findings suggest that the fixed time feeding procedure for schedule-induced polydipsia as an animal model of obsessive compulsive disorder was effective to the evaluation of pharmacological challenge study. The authors assume that the serotonin hypothesis and the serotonin-dopamine interaction hypothesis are preferred to the dopamine hypothesis in the biological etiology of obsessive-compulsive disorder.

• 한국생활과학회지
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• 제10권4호
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• pp.317-332
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• 2001

The purpose of this study was to find the purchase behavior and satisfaction levels of wholesale discount store customers. Three hundred and eighty housewives who had buying experiences from wholesale discount stores at Gunpo city, Kyeonggi province were selected. The questionnaire survey method was conducted during August 3 to August 9, 2000. The major findings were as follows ; First, the major customers using wholesale discount store were found to be age over thirties and they bought food, such as vegetables and processed food stuffs. They visited wholesale discount store once or twice a week and spent $10{\sim}50$ thousand won each purchasing. Second, most customers evaluated positively wholesale discount store, on the other hand they experienced compulsive buying or had the desire for it. Third, though they visited wholesale discount store because of lower price than other stores, they didn't agree that they were saving money through using wholesale discount store. Forth, housewife-customers' satisfaction level about whole sale discount store was not so high. Among the factors suggested, they were satisfied comparatively with the comfortable counter atmosphere and parking lot, and were dissatisfied comparatively with the long waiting time at cashier.

• 한국콘텐츠학회논문지
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• 제16권5호
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• pp.710-719
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• 2016

충동구매는 대표적인 부정적인 쇼핑성향으로 특히 인터넷 쇼핑의 경우에는 충동구매가 더욱 쉽게 발생할 수 있다. 본 연구는 인터넷 쇼핑 충동구매에 대한 이해를 넓히고자 한다. 이를 위해 인터넷에서 활발하게 쇼핑활동을 하고 있는 대학생들의 인터넷 쇼핑 충동구매성향에 영향을 미치는 요인을 살펴보았다. 분석 결과, 대학생들이 가장 즐겨 이용하는 패션제품의 충동구매성향은 '기분전환', '비계획', '구매자/제품자극', '판촉자극'의 네 가지 요인으로 구분되었다. 인터넷 패션제품 충동구매성향 유형에 영향을 미치는 개인성향을 분석한 결과, 감각추구성향, 인지욕구, 체면민감성, 자아존중감 모두 충동구매성향에 영향을 미치는 것으로 나타났다. 특히, 자아존중감이 낮고 체면민감성이 강할수록 충동구매 성향이 높아지는 것으로 보인다. 각각의 충동구매성향 유형과 개인성향의 관계에 대해서 논의하였다.

• 한국멀티미디어학회논문지
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• 제24권4호
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• pp.583-592
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• 2021

Obsessive-compulsive disorder (OCD) is a mental disorder in which a person repeated a particular thought or feels. The domain of beliefs and guilt predicted OCD symptoms. Although there were some neuroimaging studies investigating OCD symptoms, resting-state functional magnetic resonance imaging (rs-fMRI) study investigating intra-network functional connectivity associated with guilt for OCD is not reported yet. Therefore, in the current study, we assessed the differences between intra-network functional connectivity of healthy control group and OCD group using independent component analysis (ICA) method. In addition, we also aimed to investigate the correlation between changed functional connectivity and guilt score in OCD. Total 86 participants, which consisted of 42 healthy control volunteers and 44 OCD patients, acquired rs-fMRI data using the 3T MRI. After preprocessing the fMRI data, a functional connectivity was used for group independent component analysis. The results showed that OCD patients had higher score in emotion state in beliefs and lower functional connectivity in fronto-parietal network (FPN) than control group. A decrease of functional connectivity in FPN was negatively correlated with feelings of guilt in OCD. Our results suggest excessive increase in guilt negatively affect to process emotional state and behavior or cognitive processing by influencing intrinsic brain activity.

• BMB Reports
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• 제46권11호
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• pp.519-526
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• 2013

Dopamine (DA) regulates emotional and motivational behavior through the mesolimbic dopaminergic pathway. Changes in DA signaling in mesolimbic neurotransmission are widely believed to modify reward-related behaviors and are therefore closely associated with drug addiction. Recent evidence now suggests that as with drug addiction, obesity with compulsive eating behaviors involves reward circuitry of the brain, particularly the circuitry involving dopaminergic neural substrates. Increasing amounts of data from human imaging studies, together with genetic analysis, have demonstrated that obese people and drug addicts tend to show altered expression of DA D2 receptors in specific brain areas, and that similar brain areas are activated by food-related and drug-related cues. This review focuses on the functions of the DA system, with specific focus on the physiological interpretation and the role of DA D2 receptor signaling in food addiction.

• 수면정신생리
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• 제18권1호
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• pp.5-9
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• 2011

Sleep-related eating disorder (SRED) is a newly recognized parasomnia that describes a clinical condition of compulsive eating under an altered level of consciousness during sleep. Recently, it is increasingly recognized in clinical practice. The exact etiology of SRED is unclear, but it is assumed that SRED might share features of both sleepwalking and eating disorder. There have been also accumulating reports of SRED related to the administration of various psychotropic drugs, such as zolpidem, triazolam, olanzapine, and combinations of psychotropics. Especially, zolpidem in patients with underlying sleep disorders that cause frequent arousals, may cause or augment sleep related eating behavior. A thorough sleep history is essential to recognition and diagnosis of SRED. The timing, frequency, and description of food ingested during eating episodes should be elicited, and a history of concurrent psychiatric, medical, sleep disorders must also be sought and evaluated. Interestingly, dopaminergic agents as monotherapy were effective in some trials. Success with combinations of dopaminergic and opioid drugs, with the addition of sedatives, has also been reported in some case reports.

• 대한가정학회지
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• 제46권3호
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• pp.87-101
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• 2008

This research was based on a case study of a child who experienced difficulties in ego development due to her mother's compulsive and depressed behavior. Twenty-four therapeutic play sessions, including 16 sessions involving sandplay, were conducted. Based on discussions by Neumann and Kalff, the child's early psychic development and ego development were observed during these sandplay. As part af this investigation, I conducted counseling sessions in the sandbox where the atmosphere was free and safe. The sessions were based on mother-child unity with the therapist. As a result, the child exhibited restoration of mother-child unity and showed the journey of constellation of self and ego development. The results of this research indicate the effectiveness of sandplay in accelerating ego development.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제30권2호
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• pp.50-56
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• 2019

Most patients with Tourette's disorder experience an uncomfortable sensory phenomenon called the premonitory urge immediately before experiencing tics. It has been suggested that premonitory urges are associated with comorbidities such as obsessive compulsive disorder, anxiety disorders, and attention-deficit/hyperactivity disorder, although these associations have been inconsistent. Most patients experience tics as a result of the premonitory urges, and after the tics occur, most patients report that the premonitory urges are temporarily relieved. As a consequence, several studies have assessed the premonitory urge and its potential therapeutic utility. Based on the concept that the premonitory urge induces tics, behavioral treatments such as Exposure and Response Prevention and Habit Reversal Therapy have been developed. However, it is still unclear whether habituation, the main mechanism of these therapies, is directly related to their effectiveness. Moreover, the observed effects of pharmacological treatments on premonitory urges have been inconsistent.

• 융합경영연구
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• 제7권3호
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• pp.29-43
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• 2019

Research Purpose - The purpose of this study was to investigate marketing stimulation and impulsive buying of Internet shopping mall. Research Question - Despite these unstable factors, the Internet shopping mall market has become more popular than traditional distribution channels such as department stores and discount stores due to the increase in the number of Internet users, a gradual increase in the consumption of high-priced items. Research Method - The data were collected from 301 women living in Seoul, Gyeonggi, Gwangju, Daegu, and Gyeongnam province in Korea on May 2018. Statistical methods used in the study were frequency, F-test, Duncan test, factor analysis, Cronbach's α, correlation coefficient, and multiple regression. Result - All The reliability of these questions is Cronbach's α =. 775. Factor 5, which is 12.367 % explanatory power, is said to consist of three questions: price, discount bag, and no-carrying; thus, the reliability of the question is Cronbachs' α. The ratio of the five factors in body random cases was 66.096 %, and the reliability of the questions was higher than. 770 as a result of the reliability analysis.

• 무역학회지
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• 제45권5호
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• pp.201-222
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• 2020

This paper examines that determinants of BAOMAI, (i.e., behavior of Chinese tourist bulk purchase in duty free shop) with analytical framework and empirical tests. The results of applying the structural equation modeling to 196 samples suggest that Chinese tourist consumption orientations (conspicuous/compulsive/unplanned consumption) have a positive effect on BAOMAI decision value chain (perceived value and loyalty). The marketing mix of duty free shop as control variables in research framework also have a positive effect on BAOMAI perceived values (functional/social/emotional value). This paper has a contribution to prior literatures: the first empirical analysis on BAOMAI determinants with exploring scholarly definition.