• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제50권1호
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• pp.3-12
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• 2024

Chyle leaks are uncommon complications after head and neck surgeries. Although uncommon, such a complication is noteworthy mention due to its perplexing diagnosis and management strategies. This scoping review aims to highlight and emphasize the diagnosis and management options proposed in the literature. A comprehensive search was performed in PubMed, Google Scholar, Cochrane Library, and Scopus databases and identified 617 articles that were reduced to 40 studies and reports after applying the eligibility criteria. Although numerous treatment options ranging from simple, conservative measures to invasive surgical procedures have been mentioned for low-output, high-output, and massive leaks, there is no concrete evidence on the best method. Thus, a combination of management options must be customized by case for optimum results.

• BMB Reports
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• 제57권3호
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• pp.125-134
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• 2024

Whole-genome doubling (WGD), characterized by the duplication of an entire set of chromosomes, is commonly observed in various tumors, occurring in approximately 30-40% of patients with different cancer types. The effect of WGD on tumorigenesis varies depending on the context, either promoting or suppressing tumor progression. Recent advances in genomic technologies and large-scale clinical investigations have led to the identification of the complex patterns of genomic alterations underlying WGD and their functional consequences on tumorigenesis progression and prognosis. Our comprehensive review aims to summarize the causes and effects of WGD on tumorigenesis, highlighting its dualistic influence on cancer cells. We then introduce recent findings on WGD-associated molecular signatures and genetic aberrations and a novel subtype related to WGD. Finally, we discuss the clinical implications of WGD in cancer subtype classification and future therapeutic interventions. Overall, a comprehensive understanding of WGD in cancer biology is crucial to unraveling its complex role in tumorigenesis and identifying novel therapeutic strategies.

• 한국병원경영학회지
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• 제19권3호
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• pp.70-78
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• 2014

• 오토저널
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• 제31권3호
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• pp.76-80
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• 2009

• 대한환경공학회지
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• 제29권3호
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• pp.262-270
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• 2007

• 한국농촌생활과학회지
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• 제3권
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• pp.63-83
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• 1992

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 1995년도 제47차 추계 학술대회 연제집
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• pp.239-240
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• 1995

• 한국에너지공학회:학술대회논문집
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• 한국에너지공학회 2003년도 추계 학술발표회 논문집
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• pp.181-186
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• 2003

• 한국미생물생명공학회:학술대회논문집
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• 한국미생물생명공학회 2003년도 2003 Annual Meeting, BioExhibition and International Symposium
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• pp.91-94
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• 2003

• 한국신뢰성학회:학술대회논문집
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• 한국신뢰성학회 2000년도 추계학술대회
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• pp.57-74
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• 2000

This paper examined current problem of reliability assessment project on mechanical components being domestically pursued, and from the point of new view suggested directions to a comprehensive reliability assurance added quality assurance, suitable to realities in our industries.