• YAKHAK HOEJI
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• v.42 no.6
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• pp.607-612
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• 1998

In the course of our search for anti-Herpes simplex virus type I (HSV 1) substances from natural sources, we screened crude drugs for their antiviral activity using SRB assay. T he methanol extract from herb of Brassica rapa (Cruciferae) was found to inhibit HSV-1. Though bioassay-directed fractionation of the extract, anti-HSV-1 agent was isolated by chromatographic separation using Amberlite XAD-4 and Sephadex LH-20. The structure of compound I was elucidated by spectral means including $^1H-^1H$ COSY, HMQC and HMBC to be isorhamnetin 3-O-${\beta}$-D-glucopyranoside (compound I). Compound I was active against HSV-1 with the 50% effective concentration of O.42mg/ml and the 50% cytotoxicity of 5.0mg/ml.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.13 no.1
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• pp.141-156
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• 2000

Cloves are the dried flower buds of Syzygium aromaticum (L.) Mere et Perry (Myrtaceae). They have been successfully used for the management of various allergic disorders by oral administration in Korea. In this study, the author investigated the effect of an aqueous extract of Syzygium aromaticum on immediate-type hypersensitivity by anal administration. Anal administration of Syzygium aromaticum showed a marked inhibition rate in systemic hypersensitivity with a dose of 1 mg/kg 1 hr before intraperitoneal injection of compound 48/80. Anal administration of Syzygium aromaticum significantly reduced plasma histamine contents induced by compound 48/80. Anal administration of Syzygium aromaticum (1 mg/kg) also inhibited to $61.4\%$ (P<0.01) local a1lergic reaction activated by anti-dinitrophenyl (DNP) IgE. In addition, Syzygium aromaticum dose-dependently inhibited the histamine release from the peritoneal mast cells by compound 48/80 or anti-DNP IgE. When Syzygium aromaticum was added, the level of cAMP in peritoneal mast cells transiently and significantly increased about 47-fold at 10 second compared with that of basal cells. These results provide evidence that anal therapy of Syzygium aromaticum may be beneficial in the treatment of systemic and local immediate-type hypersensitivity by inhibition of histamine release from mast cells in vivo and in vitro.

• Proceedings of the KIEE Conference
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• 1999.07d
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• pp.1645-1647
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• 1999

Epoxy compound has been used as insulation material in electrical equipment because of its properties 1) Nowadays, becoming higher voltage system, the properties of interface between epoxy and its metal insert become more important. In this paper, we suggest two types semiconducting paste. One is epoxy type and the other is olephine type. After sprayed the semiconducting paste on metal insert sanded, we procedure the test one is the adhesion strength test, the other is electrical breakdown strength test. So we knew that the epoxy type paste became more higher adhesion strength than olephine type paste because of its homogeneity at the interfaces. And at the breakdown strength test, olephine type paste became less higher than epoxy type paste because of its volatility. So in this study, we suggest the optimum interface condition by adjusting the semiconducting paste and surface roughness.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.26 no.6
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• pp.1060-1068
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• 2002

Compound continuously variable transmission(CVT) mechanisms are proposed, which can offer a backward mode, a geared neutral, an underdrive mode and an overdrive mode. They are composed of a 2K-H I type differential gear unit, a V-belt type continuously variable unit(CVU), a few friction clutches and gears, and not required of a starting device as a torque converter. Compound CVT mechanisms developed here present two distinct operating modes which are a power circulation mode and a power split mode. The transition of two modes takes place at the particular CVU speed ratio. For these CVT mechanisms, performance analysis related to speed ratio, power ratio and efficiency are executed and proven by experimental studies.

• Current Research on Agriculture and Life Sciences
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• v.9
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• pp.103-108
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• 1991

The chemical characteristics of lignin in the differentiating xylem were investigated and compared with those of mature-wood. The compound middle lamella lignin deposited in the early stage of lignification of cell walls in the softwood(Larch) as well as the hardwood(Birch) was confirmed to be the so-called guaiacyl-type lignin and was found to have a relatively larger content of phenoxy hydroxyl group as terminal units and to be more abundant in condensed-type structures like as phenylcoumaran structures compared with mature-wood lingin.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.13 no.2
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• pp.211-220
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• 2000

Shini-San has been used for treatment of allergic disease in Korea. However, its effect in experimental models remains unknown. The mast cell plays a pivotal role in initiating al1ergic response by secreting intracytoplasmic granular mediators such as histamine. The present report describes an inhibitory effect of Shini-San on mast cell-mediated immediate-type al1ergic reactions. Topical application of compound 48/80 can induce an ear swelling response in normal ($WBB6F_1-+/+$) mice but not in congenic mast cell-deficient $WBB6F_1-W/W^v$ mice. Shini-San inhibited concentration dependent mast cell-dependent ear swelling response induced by compound 48/80 in normal mice. Shini-San inhibited concentration-dependent passive cutaneous anaphylaxis induced by anti-dinitrophenyl (DNP) immunoglobulin E (IgE) in rats by topical application. Shini-San also inhibited in concentration-dependent fashion the histamine release from the rat peritoneal mast cells by compound 48/80 or anti-DNP IgE. Moreover, Shini-San had a significant inhibitory effect on compound 48/80-induced systemic anaphylactic reaction. These results indicate that Shini-San inhibits immediate-type allergic reactions by inhibition of mast cell degranulation in vivo and in vitro.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.25 no.5
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• pp.54-60
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• 2011

This paper presents characteristics of frequency-dependent grounding impedance and transient grounding impedance for the carbon compound grounding electrode used in the installation of computerized electronic equipment and lightning protection system. The frequency-dependent grounding impedances were measured by applying sinusoidal currents in the frequency range from 100 [Hz] to 10[MHz], and the transient grounding impedances were examined by subjecting the impulse current with the front-time between 1~80[${\mu}s$]. As a result, the ground resistance of the carbon compound grounding electrode is less than that of another type grounding electrodes. The transient grounding impedance is relatively low and the conventional grounding impedance is rather lower than the ground resistance. The frequency-dependent grounding impedance of the carbon compound grounding electrode is capacitive and the grounding impedance is decreased with increasing the frequency of injected currents. Therefore in the case that the carbon compound grounding electrode is jointly used with large-scaled grounding electrodes, it is possible to reduce the high frequency grounding impedance of the integrated grounding electrode system.

• Archives of Pharmacal Research
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• v.8 no.3
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• pp.149-157
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• 1985

The HCL hydrolyzate of the non-histone protein fractionated from the rat liver nuclei which have been incubated inthe presence of S-adenosyl-L-[methyl-$^{14}C$ ]-methionine shows at least four unidentified radioactive peaks on a basic amino acid analysis chromatogram. One of these unknown compounds (designated as compound 3) is also formed by the rat liver homogenated with the exogenous addition of an appropriate protein substrate. Since boiled rat liver homogenate or fresh homogenate in the absence of an exogenous protein substrate failed to form compound 3, its formation can be considered to be enzyme-catalyzed. The enzyme which yields compound 3 shows a preference of protein substrate in the order of reductively methylated hemoglobin > native > histone type II-A. The rat enzyme is nuclear in location associated with chromatin, and exhibits the highest activity in the liver among various rat organs. A compound 3-forming enzyme is also present in Neurospora crassa, since endogenous formation of the compound 3 can be demonstrated with the crude extract of this mold. The chemical identity of compound 3 is not yet known. However, it resisted to the following treatments; 6 N HCL and 0.1 N Na NaOH hydrolysis at $110^{\circ}C$, OR L-amino acid oxidase.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2006.11a
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• pp.285-289
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• 2006

Recently the target area for the installation of structures have been changed from shallow water into deep one by reservation and use of the wider coastal region, and development of deep water. Additionally, great emphasis in the improved human life quality has been placed on the necessities for the preservation of the agreeable natural and coastal environments and development waterfront, recreation, and resort in the sea. However, the existing gravity-type breakwater did not appropriately cope with the recent changes of circumstances, but required the enormous construction coat for coping with them. Until now, floating breakwuater, which was adequate for the environment and construction cost, has been actively studied in the other countries including Japan. This floating breakwater has been already constructed in many places and satisfactory in poor subsoil and deep water in Japan. Also it showed the same function as a gravity-type breakwater. But floating breakwater was not control long period waves by reason of constructive characteristic. The aim of this study is to discuss field application of Floating Breakwater with Compound Plate Type(FBCPT) in coastal region by using numerical analyses and hydraulic model test.

• Journal of Mechanical Science and Technology
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• v.14 no.10
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• pp.1104-1113
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• 2000

This paper proposes an efficient reverse engineering technique for compound surfaces using a boundary detection method. This approach consists in extracting geometric edge information using a vision system, which can be used in order to drastically reduce geometric errors in the vicinity of compound surface boundaries. Through the image-processing technique and the interpolation process, boundaries are reconstructed by either analytic curves (e. g. circle, ellipse, line) or parametric curves (B-spline curve). In other regions, except boundaries, geometric data are acquired on CMM as points inspected using a touch type probe, and then they are interpolated on several surfaces using a B-spline skinning method. Finally, the boundary edge and the skinned surfaces are combined to reconstruct the final compound surface. Through simulations and experimental works, the effectiveness of the proposed method is confirmed.