• 한방비만학회지
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• 제9권1호
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• pp.23-36
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• 2009

Objectives The purpose of this study is to research related to Taeeumjowui-Tang(Taiyintiaowei-tang) in oriental medicine. Methods "Taeeumjowui-Tang" was used as a search term. In order to see detail review, we classified all the searched study into type, method, purpose, item of evaluation, composition of herbal medication. Results We found out total twenty six studies. They were fifteen pieces of experimental studies, five clinical case studies, five case reports and one literature review according to type and method. There were fourteen thesis that experiments on efficacy and effect in the purpose of study. Only one thesis showed about stability and toxicity. There were eleven prescription of different composition and dosage. In the item of evaluation, serum biochemical analysis, cell study, body and organ weight, food consumption, body mass index, waist circumference, waist-hip circumference ratio, bioelectrical impedance analysis were used. Conclusion To improve more objective and continuous research in oriental medicine, it is needed unity about prescription and dosage, activation of clinical trial research and variation of research subject.

• 한국한의학연구원논문집
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• 제18권1호
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• pp.25-34
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• 2012

Objective : This study was carried out with focus on written by Joh, Taek-seung (曺澤承) and Joh, Byeong-who(曺秉矦) in the relation of father and son in 1933. This book is a medical book including rare data, which has never been reported to academic circles all this while. Method : First, this study looked into the authors of this book and its history of publication. Further, this study analyzed the composition and contents of this book. Lastly, this study summed up the meaning of this book from the standpoint of medical history. Result : The authors were Confucian doctors who were active in the latter era of the Joseon Dynasty and also in the period of Japanese colonial rule. They lived in Haenam district of Jeonlanam-do, and cured its neighboring local residents while studying. They published the book of by putting together their own medical experiences. The authors suggested their remedial prescription according to gender and age whereas Zhang Zhongjing(張仲景) suggested the remedial prescription according to Six-Meridian Pattern Identification & Syndrome Differentiation(六經辨證). In addition, the authors of gave weight to the relationship with internal damage. Additionally, the authors not only thought much of the relationship between internal damage and external damage but also thought of the weakness and strength of the healthy qi, and the new and the old of a disease as an important clue to medical treatment. It seems that such contents was influenced by (東醫寶鑑). Conclusion : shows the results of the research on which was spontaneously conducted in Joseon.

• 동아시아식생활학회지
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• 제16권2호
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• pp.136-144
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• 2006

This research evaluated how the composition of Yak-sun(oriental diet therapy), taken as a nutritional supplement with daily meals, can effect the medical condition of those suffering from modern diseases like obesity and hyperlipideia. We produced Yak-sun tea, determined its nutrient composition and physical characteristics and evaluated how this tea effects affects the active oxygen concentration inside the body by clinical practices. The study results indicated that this tea significantly decrease active oxygen concentration. We think that scientific and objective evaluation was done on the components of Yak-sun tea prescription. We concluded that we could apply the components not only in the form of tea, but also in other food forms. The information we received from this conclusion will provide basic information for the application of oriental medicinal resources into other foods and will also be a steppingstone in the field of functional food research for the development of medicinal herbs which is already an important research field world-wide.

• 대한한의학방제학회지
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• 제19권2호
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• pp.161-178
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• 2011

동의보감(東醫寶鑑) 중(中) 향부자(香附子)가 주약(主藥)으로 배오(配伍)된 85개 처방(處方)에 대하여 자료조사(資料調査)를 한 바 다음과 같이 요약(要約)할 수 있었다. 1. 향부자(香附子)가 주약(主藥)으로 구성(構成)된 방제(方劑)의 치료영역(治療領域)에 따른 처방빈도는 부인문(婦人門)이 16.4%, 포문(胞門)이 15.2%, 기문(氣門)이 10.5%, 적취문(積聚門)이 8.1% 순으로 많은 빈도수를 차지하였으며, 그 밖에도 20개 치료영역(治療領域)에 사용되었음을 알 수 있었다. 2. 향부자(香附子)는 구사(求嗣), 월경부조(月經不調), 기울(氣鬱), 기통(氣痛), 적취(積聚)등의 병증(病症)에 가장 많이 활용되고 있었으며, 그밖에도 55개 병증에 사용하였다. 3. 향부자(香附子)가 주약(主藥)으로 사용된 처방(處方)의 병인병리(病因病理)는 제기울체(諸氣鬱滯), 칠정(七情), 담음(痰飮), 식상(食傷), 풍한(風寒)등의 병리(病理)가 많았다. 4. 향부자(香附子)가 주약(主藥)으로 사용된 처방(處方)의 1회 향부자(香附子) 사용량은 6리(厘)~6전(錢)까지 이며, 1전(錢)을 가장 많이 사용하였다. 5. 향부자(香附子)는 배오(配伍)되는 약물(藥物)과 처방에 따라 이기해울(理氣解鬱), 소간이기(疎肝理氣), 조경지통(調經止痛)등의 다양한 작용을 하는 것을 알 수 있으며, 향부자(香附子)가 주약(主藥)으로 사용된 처방(處方)의 기본방(基本方)으로는 교감단(交感丹), 이진탕(二陳湯), 육미삼릉환(六味三稜丸)을 가장 많이 사용하였음을 알 수 있다.

• 사상체질의학회지
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• 제22권3호
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• pp.43-50
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• 2010

1. Objectives: The purpose of this study is to understand the origin, changes and the constructive principles of Hyangsayangyitang (XiangShaYangWeiTang). 2. Methods: Hyangsayangyi-tang and other related prescriptions were analyzed in terms of pathology, based on "Donguibogam(東醫寶鑑)", "Donguisusebowon Chobongwon(東醫壽世保元 草本卷)", "Donguisusebowon Gabobon(東醫壽世保元 甲午本)", "Donguisusebowon Sinchukbon(東醫壽世保元 辛丑本)". 3. Results and Conclusions: (1) The origin of Hyangsayangyi-tang is Hyangsayukgunja-tang from "Gongshin Uigamseo(龔信 醫鑑書"). Hyangsayangyi-tang inherited some of the principles from"Euihangangmok(醫學綱目)" Jeonssiyigong-san's (全氏異功散) application. (2) "Gabobon(甲午本)"'s prescription emphasizes the effect of lossen up by using Pogostemonis Herba(藿香). "Sinchukbon(辛丑本)"'s prescription emphasizes the effect of warm up stomach by using Zingiberis Rhizoma(乾薑). (3) Ginseng Radix(人蔘), Atractlodis Rhizoma White(白朮), Glycyrrhizae Radix(甘草), Paeoniae Radix Alba(白芍藥) support Soeumin's spleen root (脾元), and Zingiberis Rhizoma(乾薑), Myristicae Semen(肉豆蔲) warm up stomach, and Pinelliae Rhizoma(半夏), Citri Pericarpium(陳皮) circulate Qi, Crataegi Fructus(山楂), Amomi Fructus(砂仁), Cyperi Rhizoma(香附子) encourage digestion to maintain descending Yin.

• 대한한의학방제학회지
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• 제30권3호
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• pp.165-174
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• 2022

Objectives: Donguibogam has helped progress of Eastern medicine across Asia and almost all of Korean medicine doctors still use the book as a classic reference. In this study, the prescriptions used in the treatment of stroke in Donguibogam are analyzed and the results are to be used for our subsequent studies. Methods: The frequency of use of prescriptions and the frequency of combination of medicines were analyzed from 89 prescriptions used in the Stroke chapter of Donguibogam, and it was intended to derive a combination prescription and a monosyllabic medicine that can be effectively used in the treatment of stroke for preclinical studies. Results: Ganghwalyupung-tang (羌活愈風湯) was the most mentioned prescription among 89 prescriptions, and Glycyrrhizae Radix et Rhizoma, among 165 species of medicines used in the 89 prescriptions, mixed in 55 prescriptions. However, considering the ratio of frequently used medicines, Sagunja-tang (四君子湯) was the highest in terms of composition ratio. Conclusions: Through this study, Glycyrrhizae Radix et Rhizoma and Sagunja-tang were selected as materials for our subsequent studies.

• 대한한의학회지
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• 제35권1호
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• pp.99-113
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• 2014

Objectives: To provide theoretical basis for the classification of medicinal moxibustion(藥灸劑) in Health Insurance Medical Benefit in Korea through investigating trend of judicial precedents on indirect moxibustion and usage of medicinal moxibustion in "Donguibogam". Methods: We analyzed statistical data of moxibustion from Health Insurance Review & Assessment Service and National Health Insurance Statistical Yearbook. We investigated major judicial precedents on indirect moxibustion to find out some trend and we searched the usages of medicinal moxibustion in "ZhenJiuDaCheng" and "Donguibogam". Results: According to recent judicial precedents, indirect moxibustion with equipment is no loner regarded as Korean Medical Procedure. In composition of 'Oriental Health Treatment', amount for acupuncture has gradually decreased instead, amount for moxibustion has increased steadily for 5 years. Medicinal moxibustion(藥灸劑) is often used as a form of indirect medicinal moxibustion with moxa in "Donguibogam". Argyi Folium, Moschus, Natrii Chloridium, Radix Preparata, Realgar and Olibanum are most frequently used for medicinal moxibustion in "Donguibogam". Medicinal moxibustions are composed of simple prescription or herb-pair or multiple prescription in "Donguibogam". Conclusions: In Health Insurance Medical Benefit in Korea, under the division of moxibustion, direct medicinal moxibustion and indirect medicinal moxibustion should be classified in addition.

• 한방안이비인후피부과학회지
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• 제14권2호
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• pp.89-111
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• 2001

In order to investigate the effects of GamiTakliSodocyum(GTS) on wound healing, migration of epidermis, formation of granulation tissue and number of capillary within the granulation tissue were measured in diabetic mice by local application and NZW rabbits by local application and prescription of medicine in vivo, and proliferation of human epidermal keratinocytes and human dermal fibroblasts and composition of extracellular matrix were measured in vitro. The results were summerized as follows. 1. $2\%,\;10\%$ GTS remarkably increased migration of epidermis in diabetic mice by local application. 2. $2\%,\;10\%$ GTS remarkably increased formation of granulation tissue, number of neovascularization within the granulation tissue in diabetic mice by local application. 3. 5\%,\;10\%$ GTS remarkably increased migration of epidermis in NZW rabbits by local application. 4. $5\%,\;10\%$ GTS remarkably increased fonnation of granulation tissue, number of neovascularization within the granulation tissue in NZW rabbits by local application. 5. $5\%,\;10\%$ GTS increased migration of epidennis in NZW rabbits by prescription of medicine. 6. $5\%,\;10\%$ GTS increased formation of granulation tissue, number of neovascularization within the granulation tissue in NZW rabbits by prescription of medicine. 7. GTS didn't show effect on the proliferation of human epidermal keratinocytes. 8. GTS increased the proliferation of cultured human dermal fibroblasts. 9. GTS increased the expression of procoliagen ${\alpha}1(I) mRNA in cultured human dermal fibroblasts. 10. GTS increased the expression of fibronectin mRNA in cultured human dennal fibroblasts according to dosage of GTS using northern blot hybridization but didn't increase, using RT-PCR. From the above results, it is conclude that GTS might use on wound healing.

• 동의생리병리학회지
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• 제31권3호
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• pp.153-158
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• 2017

As social interest in acne treatment has grown, various external preparations have been developed and studied. So, we investigated the external prescription which can treat acne in medical classics, then reviewed and divided it by dynasty. The data for analysis of Herbal formula was taken from 'medicine Dictionary of traditional Chinese medicine prescriptions(中醫方劑大辭典)'. 31 external medicines were searched, 3 were before song(宋) dynasty, 11 were Song(宋) dynasty, 11 were Yuan(元) dynasty, 7 were Ming(明) dynasty and 7 were Qing(淸) dynasty. The recipe and usage were only making them pill(丸) and paste(膏) using grinded medicinal herbs, then rubbing to face. As the age developed, unique manufacturing process(i.e fermentation method), and usage(i.e time-based usage, herbal medicine extracts for wash) were proposed. The external application with oriental medicine for acne used with Angelicae Gahuricae Radix(n=12), Bletillae Rhizoma(n=8), Syzygii Flos, Saposhnikoviae Radix(n=7) and so on. In particular, Bletillae Rhizoma was searched with high frequency in this study, but it was not included or studied in patent composition. The results of this study will provide basic data for future experiments and clinical studies.

• 대한본초학회지
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• 제28권4호
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• pp.93-100
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• 2013

Objectives : This study was to evaluate the anti-inflammatory and anti-pruritic effects of WSY-1075 composited with Corni Fructus, Angelica gigantis Radix, Lycii Fructus, Ginseng Radix, Cervi parvum Cornu and Cinnamomi Cortex in rat peritoneal mast cells (RPMCs) and scratching mouse model. Methods : WSY-1075 was prepared by extracting with 30% ethanol. In the present study, we investigated the effect of WSY-1075 on the production of tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin-$1{\beta}$ (IL-$1{\beta}$) and histamine in rat peritoneal mast cells (RPMCs) activated with phorbol 12-myristate 13-acetate (PMA) plus calcium ionophore A23187, and on the scratching behavior in mice treated with pruriogens. Results : WSY-1075 was not cytotoxic effect in used all concentration. PMA plus A23187 treatment significantly increased TNF-${\alpha}$, IL-$1{\beta}$ and IL-6 production compared with media control in RPMCs. However, TNF-${\alpha}$, $IL1{\beta}$ and IL-6 production increased by PMA plus A23187 treatment were significantly inhibited by WSY-1075 (200 ${\mu}g/mL$ and 400 ${\mu}g/mL$). WSY-1075 also inhibited the histamine release from RPMCs stimulated by compound 48/80, which promotes histamine release. Moreover, WSY-1075 administration had an inhibitory effects on the scratching behavior induced by pruritogen (compound 48/80, histamine, serotonin and substence P) in ICR mice. Conclusion : These results suggest that WSY-1075 administration (200 mg/kg or 400 mg/kg) has the anti-inflammatory and anti-pruritic effects on the activated rat peritoneal mast cell and mouse pruritus. WSY-1075 has a potential use as a composition of medicinal plants for treatment against inflammation- and pruritus-related disease.