• 대한기계학회논문집A
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• 제20권4호
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• pp.1263-1274
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• 1996

In this paper, as elastic-plastic fracture toughness test under mixed mode loading was proposed using a single edge-cracked specimen subjected to bending moment(M), shearing force(F), and twisting moment(T). The J-integral of a crack in the specimen is expressed in the form J=$J_I$+ $J_II$$J_III$, where $J_I$, $J_II$ and $J_III$ are the components of mode I, mode II and mode III deformation, respectively. $J_I$, $J_II$ and $J_III$ can be estimated from M-$\theta$ ($\theta$;crack opening angle), F-U(U; crack shear displacement) and T-$\alpha$ ($\alpha$;crack twisting angle). In order to obtain the the M<-TEX>$\theta$, F-U and T-$\alpha$ diagram inreal time, a new deformaiton gage for mixed mode loading was proposed using the optical position sensing device(PSD). The elastic-plastic fracture toughness test was carried out with an aluminum alloy. The loading apparatus was designed and manufactured for this experiment. For the loading condition of the crack initatio in the mixed mode, the MMT -3(mode I+ mode II+ mode III) has the lowest values out of the all specimens. This implies that MMT-3 is possible of the crackinitation at lower load, if the specimen acts on together with the torque under the same loading condition. An elastic-plastic fracture toughness test using the PSD brings a successful experimentation in measuring the crack deformation(mode I+ mode II+ mode III).

• Applied Biological Chemistry
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• 제7권
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• pp.85-91
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• 1966

한국(韓國) 재배(栽培) 대두(大豆) 25품종(品種)을 선택하여 각(各) 품종(品種)의 단백질(蛋白質) 패턴을 여지전기영동법(濾紙電氣泳動法)으로 시행하여 품종간(品種間)의 차이(差異)를 비교(比較)해 보았다. 이 방법(方法)으로 5종(種)의 단백질(蛋白質)을 분리(分離)할 수 있었으며 각(各) 품종간(品種間)의 정량적(定量的)인 함율차(含率差)를 찾아 볼 수 있었다. 각(各) 단백질(蛋白質) 성분간(成分間)의 평균(平均) 함량비(含量比)는 다음과 같다. I 14.47% II 7.22% III 4.43% IV 71.70% V 2.18% 상기(上記) 각획분(各劃分)을 동정(同定)하여 본 결과(結果)는 다음과 같다.

• Journal of Ginseng Research
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• 제14권2호
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• pp.217-220
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• 1990

Two lignanes, Comp.-I, mp 108-1$0^{\circ}C$ and Comp.-II 50-52$^{\circ}$were isolated from Korea ginseng extract by repeated column chromatographic purification. Comp.-I was identified as gomisin-N and Comp.-II as gomisin-A by spectrometric analysis, both of which have already been described as the anti-hepatotoxic lignan components of Schizandra chinesis Bail.

• 대한기계학회논문집
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• 제17권2호
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• pp.313-330
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• 1993

The propagating crack problems under dynamic plane mode in orthotropic material is studied in this paper. To analyze the dynamic fracture problems in orthortropic material, it is important to know the dynamic stress components and dynamic displacement components around the crack tip. Therefore the dynamic stress components of dynamic stress field and dynamic displacement components of dynamic displacement field in the crack tip of orthotropic material under the dynamic load and the steady state in crack propagation were derived. When the crack propagation speed approachs to zero, the dynamic stress component and dynamic displacement components derived in this study are identical to the those of static state. In addition, the relationships between dynamic stress intensity factor and dynamic energy release rate are determinded by using the concept of crack closure closure energy with the dynamic stresses and represented according to physical properties of the orthotrophic material and crack speeds. The faster the crack velocity, the greater the stress value of stress components in crack tip. The stress value of the stress component of crack tip is greater when fiber direction coincides with the crack propagation than when fider direction is normal to the crack propagation.

• Archives of Pharmacal Research
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• 제11권3호
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• pp.240-243
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• 1988

The hexane extract from Nutmeg, the seed of Myristica fragrans significantly inhibited hepatic drug-metabolizing enzyme activity. Through systematic fractionation by $SiO_2$ column and vacuum liquid chromatography monitoring by bioassay, three components, myristicin, (I), licarin-B (II) and dehydrodiisoeugenol (III) were isolated as active principles. Compounds II and III, with a single treatment (200mg/kg, i.p.) showed not only a significant prolongation of hexobarbital-induced sleeping time but also a significant inhibition of aminopyrine N-demethylase and hexobarbital hydroxylase activities in mice. Compounds I and II provoked a sleep episode at a subhypnotic dose of HB, suggesting that they possess CNS-depressant properties.

• 한국식품저장유통학회지
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• 제19권3호
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• pp.433-437
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• 2012

감자를 이용해서 증류식 소주를 제조하고 전통방식의 소주고리 증류 및 감압증류 조건에 따른 퓨젤유 및 휘발성 성분의 특성에 대해 조사하였다. 감자소주의 퓨젤유 함량은 감자술덧을 감압 증류하였을 때 높았으며, isoamyl alcohol, isobutyl alcohol, n-propanol의 상대비는 전통방식 증류주가 3.1 : 0.8 : 1.0, 감압 증류주가 4.0 : 1.2 : 1.0 이었다. 감자소주의 휘발성 성분 chromatogram은 증류조건에 따라 뚜렷한 차이를 나타내었고, 휘발성 성분으로는 감자소주(I)에서 alcohol류 4종, ester류 6종, aldehyde류 1종, acid류 1종, 감자소주(II)에서 alcohol류 7종, ester류 14종, aldehyde류 2종, acid류 1종 및 기타 성분 3종이 확인되었다. 감자소주(II)는 향에 대한 선호도가 감자소주(I)보다 유의적으로 높았다.

• 한국가정과학회지
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• 제9권1호
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• pp.81-88
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• 2006

IGFs and IGFBPs have an important role in controlling glucose homeostasis. This study was conducted to investigate the changes of insulin-like growth factor(IGF)-I. IGF-II and IGF binding proteins (IGFBPs) on fasting and postprandial state in Korean diabetes, Twenty eight healthy subjects and fifty seven diabetic patients participated in this study. The healthy subjects were not knowingly suffered from any disease and were not receiving any medical treatment, and diabetic subjects were undergo medical treatment, continuously. Weight and height were measured and body mass index (BMI) was calculated as weight (kg) divided by the square of height (m2). Blood pressure was measured. Plasma lipid profiles were analyzed by enzymatic methods, plasma Insulin and glucose levels were measured in fasting and postprandial state, respectively. The levels of serum IGFs and IGFBP-3 were measured by radioimmunoassay (RIA). The levels of glucose and insulin were significantly higher in diabetes than normal subjects on fasting as well as postprandial state (p<0.0l). The levels of IGF-I was significantly lower in diabetes than normal subjects, however in postprandial state, there was no significant difference between diabetes and control subjects, The levels of IGF-II were significantly lower in diabetes than control subjects both fasting and postpradial state, The level of IGFBP-3 were not significantly different between diabetes and normal subjects. Fasting IGF-I, IGF-II and IGFBP-3 levels were positively correlated with those levels on postprandial state, fasting IGe levels of IGF-I levels were positively correlated with fasting insulin levels, and postprandial IGF-I levels were positively correlated with fasting glucose, postprandial insulin and postprandial insulin levels, plasma triglyceride levels were correlated with plasma triglyceride levels. The IGFBP-3 levels were not correlated with IGF components, glucose, insulin and plasma lipids, These results demonstrate that in diabetes, the components IGF-I/IGFBPs system were significantly correlated with plsma glucose and insulin levels both fasting and postprandial state.

• KSBB Journal
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• 제17권6호
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• pp.549-554
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• 2002

한지로 된 고서적의 가수분해가 Trichoderma viride로부터 분리한 endoglucanase I, exoglucanase II와 endo-exo혼합효소 (I：I, weight ratio)에 의하여 수행되었다. Endoglucanase I, exoglucanase II와 endo-exo혼합효소에 의한 가수분해 최적pH는 각각 4.5, 5.5, 5.0으로 나타났다. 이들 결과들은 지류문화재의 열화가 산성조건에서 셀룰라아제의 활성을 증가시켜 촉진될 수 있음을 보여준다. 또한 이들 효소들에 의한 분해에 있어서 최적 분해온도는 모두 5$0^{\circ}C$를 보여주었다. 고서적의 재생펄프를 이들 효소로 처리했을 때 수율(yield)과 물리적 강도(physical strength)를 살펴보면, 수율은 이들 효소의 농도 증가와 함께 감소함을 보여 주었다. 특히 endo-exo혼합효소로 처리했을 때 가장 낮은 값을 보여 주었다. 이는 endo성분과 exo성분의 협동작용(synergistic action)에 의한 것으로 생각할 수 있다. 물리적 강도는 exo II로 처리했을 경우 농도 증가에 따라 향상됨을 보여 주었으며, exoglucanase II와 endo-exo혼합효소로 처리했을 경우는 농도에 따라 감소함을 보여 주었다. 이들 결과들은 고서적의 분해(열화)가 endoclucanase에 의한 것임을 보여 준다. 즉 지류문화재의 물리적 강도를 저하시키는 주요 성분 효소는 endoglucanase이며 지류문화재의 효과적인 보존을 위해서는 endoglucanase성분의 활성을 억제시킬 필요가 있다.

• 대한수학회보
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• 제41권1호
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• pp.125-135
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• 2004

One of the intriguing and fundamental algorithmic graph problems is the computation of the strongly connected components of a directed graph G. In this paper we first introduce a simple procedure for determining the location of the nonzero elements occurring in $B^{-1}$ without fully inverting B, where EB\;{\equiv}\;(b_{ij)\;and\;B^T$ are diagonally dominant matrices with $b_{ii}\;>\;0$ for all i and $b_{ij}\;{\leq}\;0$, for $i\;{\neq}\;j$, and then, as an application, show that all of the strongly connected components of a directed graph G can be recognized by the location of the nonzero elements occurring in the matrix $C(G)\;=\;(D\;-\;A(G))^{-1}$. Here A(G) is an adjacency matrix of G and D is an arbitrary scalar matrix such that (D - A(G)) becomes a diagonally dominant matrix.

• 대한소아치과학회지
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• 제33권3호
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• pp.401-410
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• 2006

치아 우식은 구강 내 미생물에 의해 치아 석회 조직의 일부가 용해되고 파괴되는 감염성 질환이다. 치아 우식의 원인균은 Streptococcus mutans와 같은 Mutans streptococci로 알려져 있고, 이 미생물이 치면에 접착하여 군집을 형성하는 능력이 균의 독성에 중요한 역할을 한다. S. mutans가 치면의 타액성 피막에 부착하는 데에는 AgI/II와 같은 세포표면의 섬유성 단백질을 매개로 한다. 그러므로, AgI/II는 S. mutans GS-5에 대한 백신 개발에 적절한 목표가 된다. 본 실험은 S. mutans GS-5로부터 AgI/II 유전자를 복제하고 염기서열분석을 하였다. 복제된 AgI/II와 앞서 보고된 S. mutans GS-5의 해당 부위의 280개의 핵산은 완벽하게 일치하였다. 복제된 유전자를 두 부위로 절단하여 형질전환을 통해 재조합 단백질인 AgI/IImr을 얻었고, 정제된 재조합 단백질을 쥐에게 주입하여 다클론 항체를 얻었다. 추출된 다클론 항체는 AgI/IImr항원단백질에 반응하였고, 대조군으로 쓰인 단백질에는 반응하지 않았다.