• Title/Summary/Keyword: component failure

Search Result 724, Processing Time 0.027 seconds

Nutrition Support in Critically Ill Cancer Patient Receiving Extracorporeal Membrane Oxygenation: A Case Report

  • Ji-Yeon Kim;Gyung-Ah Wie;Kyoung-A Ryu;So-Young Kim
    • Clinical Nutrition Research
    • /
    • v.12 no.2
    • /
    • pp.91-98
    • /
    • 2023
  • Adequate nutritional support is crucial in preventing complications and improving outcomes in critically ill patients. Extracorporeal membrane oxygenation (ECMO) is a mode of supportive care for patients with respiratory and/or cardiac failure. ECMO patients frequently exhibit a hypermetabolic state characterized by protein catabolism and insulin resistance, which can lead to malnutrition. Nutritional therapy is a vital component of intensive care, but its optimal administration for ECMO patients is unknown. This case report aims to provide insights into effective nutritional management for critically ill patients undergoing ECMO therapy. The patient was a 72-year-old male with a history of gastric and lung cancer who underwent a lobectomy complicated by bronchopleural fistula, postoperative bleeding, pneumonia, and acute respiratory distress syndrome (ARDS). The patient's nutritional status was assessed indicating a high risk of malnutrition, using the modified Nutrition Risk in the Critically Ill (mNUTRIC) Score. Nutritional support was administered based on the recommendations of European Society for Clinical Nutrition and Metabolism (ESPEN) and the American Society for Parenteral and Enteral Nutrition (ASPEN), with energy requirements set at 25-30 kcal/kg/d and protein requirements set at 1.2-2.0 g/kg/day. The patient received parenteral nutrition until the enteral nutrition target amount was reached, with zinc supplements for wound healing. The study highlights the need for further research on proactive and effective nutritional support for ECMO patients to improve compliance and prognosis.

Experimental and numerical investigation on the seismic behavior of the sector lead rubber damper

  • Xin Xu;Yun Zhou;Zhang Yan Chen;Song Wang;Ke Jiang
    • Earthquakes and Structures
    • /
    • v.26 no.3
    • /
    • pp.203-218
    • /
    • 2024
  • Beam-column joints in the frame structure are at high risk of brittle shear failure which would lead to significant residual deformation and even the collapse of the structure during an earthquake. In order to improve the damage issue and enhance the recoverability of the beam-column joints, a sector lead rubber damper (SLRD) has been developed. The SLRD can increase the bearing capacity and energy dissipation capacity, and also demonstrating recoverability of seismic performance following cyclic loading. In this paper, the hysteretic behavior of SLRD was experimentally investigated in terms of the regular hysteretic behavior, large deformation behavior and fatigue behavior. Furthermore, a parametric analysis was performed to study the influence of the primary design parameters on the hysteretic behavior of SLRD. The results show that SLRD resist the exerted loading through the shear capacity of both rubber parts coupled with the lead cores in the pre-yielding stage of lead cores. In the post-yielding phase, it is only the rubber parts of the SLRD that provide the shear capacity while the lead cores primarily dissipate the energy through shear deformation. The SLRD possesses a robust capacity for large deformation and can sustain hysteretic behavior when subjected to a loading rotation angle of 1/7 (equivalent to 200% shear strain of the rubber component). Furthermore, it demonstrates excellent fatigue resistance, with a degradation of critical behavior indices by no more than 15% in comparison to initial values even after 30 cycles. As for the designing practice of SLRD, it is recommended to adopt the double lead core scheme, along with a rubber material having the lowest possible shear modulus while meeting the desired bearing capacity and a thickness ratio of 0.4 to 0.5 for the thin steel plate.

Method for the Assembly of a High-density Multi-channel Deformable Mirror for High Energy Lasers (고에너지 레이저용 고밀집 다채널 실리콘-카바이드 변형거울의 정밀 조립 방법)

  • Hyug-Gyo Rhee;Sunho Cho;Sihyun Kim;Jaehyun Lee;Pilseong Kang
    • Korean Journal of Optics and Photonics
    • /
    • v.35 no.4
    • /
    • pp.170-174
    • /
    • 2024
  • A laser beam propagating in free space can be negatively affected by atmospheric turbulence. To overcome this and correct the wavefront error of the laser beam itself, a deformable mirror (DM), which is a key component of adaptive optics, is widely used. In this paper, a novel precision assembling method is suggested for a multi-channel high-density DM. The material of the mirror sheet of the DM is silicon carbide (SiC), and the actuator is a stacked-type lead-magnesium-niobate (Pb(Mg1/3Nb2/3)O3; PMN). To connect the mirror sheet and each actuator, a flexure is inserted. The flexure can make the DM operate with full strokes without the failure of adhesive. A series of jigs were designed and applied in order to assemble these three parts (the mirror sheet, actuators, and flexures) precisely. After assembly, the performance of the DM was also checked.

Development of dynamics simulation model for 3-point hitch of agricultural tractor during plow tillage

  • Mo A Son;Seung Yun Baek;Seung Min Baek;Hyeon Ho Jeon;Ryu Gap Lim;Yong Joo Kim
    • Korean Journal of Agricultural Science
    • /
    • v.49 no.4
    • /
    • pp.989-1000
    • /
    • 2022
  • Agricultural operations are performed in uneven environments by attaching an implement on the 3-point hitch of a tractor. A high load is thus placed on the 3-point hitch, and fatigue and failure of the hitch may occur during agricultural operations. In this study, a dynamic simulation model was developed to predict the load occurring on the eyebolt of a 3-point hitch, which is the main damaged component. The simulation model was developed and validated using agricultural data as simulation input and validation data. The dynamics model was developed using the specifications of a 78 kW class tractor. A measurement system was constructed to measure the simulation input and validation data. The simulation model was validated using a traction load on an eye bolt, which was measured during plow tillage operation. The measurement results showed that the average traction load on the left and right lower link and the top link were 8,099.97, 4,943.06, and 636.11 N, respectively. The simulation results and the measured traction load on the left eyebolt were respectively 610.30 and 597.15 N. The simulation results and measured traction load on the left eyebolt were respectively 1,179.78, and 1,145.06 N. The error between the simulation and measurement data was roughly 2% on the left eyebolt and 3% on the right eyebolt.

The Liability of Participants in Commercial Space Ventures and Space Insurance (상업우주사업(商業宇宙事業) 참가기업(參加企業)의 책임(責任)과 우주보험(宇宙保險))

  • Lee, Kang-Bin
    • The Korean Journal of Air & Space Law and Policy
    • /
    • v.5
    • /
    • pp.101-118
    • /
    • 1993
  • Generally there is no law and liability system which applies particulary to commercial space ventures. There are several international treaties and national statutes which deal with space ventures, but their impact on the liability of commercial space ventures has not been significant. Every state law in the United States will impose both tort and contract liability on those responsible for injuries or losses caused by defective products or by services performed negligently. As with the providers of other products and services, those who participate in commercial space ventures have exposure to liability in both tort and contract which is limited to the extent of the resulting damage The manufacturer of a small and cheap component which caused a satellite to fail to reach orbit or to operate nominally has the same exposure to liability as the provider of launch vehicle or the manufacturer of satellite into which the component was incorporaded. Considering the enormity of losses which may result from launch failure or satellite failure, those participated in commercial space ventures will do their best to limit their exposure to liability by contract to the extent permitted by law. In most states of the United States, contracts which limit or disclaim the liability are enforceable with respect to claims for losses or damage to property if they are drafted in compliance with the requirements of the applicable law. In California an attempt to disclaim the liability for one's own negligence will be enforceable only if the contract states explicitly that the parties intend to have the disclaimer apply to negligence claims. Most state laws of the United States will refuse to enforce contracts which attempt to disclaim the liability for gross negligence on public policy grounds. However, the public policy which favoured disclaiming the liability as to gross negligence for providers of launch services was pronounced by the United States Congress in the 1988 Amendments to the 1984 Commercial Space Launch Act. To extend the disclaimer of liability to remote purchasers, the contract of resale should state expressly that the disclaimer applies for the benefit of all contractors and subcontractors who participated in producing the product. This situation may occur when the purchaser of a satellite which has failed to reach orbit has not contracted directly with the provider of launch services. Contracts for launch services usually contain cross-waiver of liability clauses by which each participant in the launch agrees to be responsible for it's own loss and to waive any claims which it may have against other participants. The crosswaiver of liability clause may apply to the participants in the launch who are parties to the launch services agreement, but not apply to their subcontractors. The role of insurance in responding to many risks has been critical in assisting commercial space ventures grow. Today traditional property and liability insurance, such as pre-launch, launch and in-orbit insurance and third party liability insurance, have become mandatory parts of most space projects. The manufacture and pre-launch insurance covers direct physical loss or damage to the satellite, its apogee kick moter and including its related launch equipment from commencement of loading operations at the manufacture's plant until lift off. The launch and early orbit insurance covers the satellite for physical loss or damage from attachment of risk through to commissioning and for some period of initial operation between 180 days and 12 months after launch. The in-orbit insurance covers physical loss of or damage to the satellite occuring during or caused by an event during the policy period. The third party liability insurance covers the satellite owner' s liability exposure at the launch site and liability arising out of the launch and operation in orbit. In conclusion, the liability in commercial space ventures extends to any organization which participates in providing products and services used in the venture. Accordingly, it is essential for any organization participating in commercial space ventures to contractually disclaim its liability to the extent permitted by law. To achieve the effective disclaimers, it is necessary to determine the applicable law and to understand the requirements of the law which will govern the terms of the contract. A great deal of funds have been used in R&D for commercial space ventures to increase reliability, safety and success. However, the historical reliability of launches and success for commercial space ventures have proved to be slightly lower than we would have wished for. Space insurance has played an important role in reducing the high risks present in commercial space ventures.

  • PDF

Restless Legs Syndrome and Quality of Life in Hemodialysis Patients (혈액투석을 받는 만성신부전 환자에서 하지불안증후군과 삶의 질)

  • Choi, Hyun-Seok;Kang, Seung-Gul;Boo, Chang-Su;Lee, Heon-Jeong;Cho, Won-Yong;Kim, Hyoung-Kyu;Kim, Leen
    • Sleep Medicine and Psychophysiology
    • /
    • v.14 no.2
    • /
    • pp.99-106
    • /
    • 2007
  • Objective: Restless legs syndrome (RLS) is known to be associated with chronic renal failure (CRF) patients on hemodialysis, however the prevalence of RLS in CRF patients on hemodialysis is variable due to different diagnostic criteria or dialysis technique. A few reports have indicated the association between RLS symptom and lower life quality in CRF patients on hemodialysis. This study aims to investigate the prevalence of RLS and its association with the quality of life in CRF patients of a single dialysis unit in Korea. Methods: A total of 83 Korean CRF patients on hemodialysis in the Korea University Hospital were examined. International Restless Legs Syndrome Study Group (IRLSSG) criteria and International Restless Legs Scale (IRLS) were used to determine the diagnosis and severity of RLS. Questionnaires including Athens Insomnia Scale (AIS), Epworth sleepiness scale (ESS), and Medical Outcome Study Form-36 (SF-36) were administered to all the patients for the assessment of sleep and quality of life. Hamilton Depression Rating Scale (HDRS) and Clinical Global Impression (CGI) were also measured for depression and status of mental illness by psychiatrist. Results: Of the 83 patients, 31 (37.3%) patients were found to have RLS and 43 (51.8%) patients met at least one of the RLS diagnostic criteria. The AIS (t=2.40, p=0.019), ESS (t=2.41, p=0.018), HDRS (t=3.85, p<0.001) and CGI (t=3.52, p=0.001) were higher in the subjects with RLS compared to other subjects. The SF-36 scores were significantly lower in the patients with RLS except physical functioning and bodily pain. Total (p=0.005), physical component (p=0.019), and mental component scores (p=0.019) of SF-36 were significantly lower in patients with more severe RLS symptoms. Conclusion: There was significant relationship between RLS and poor quality of sleep and life. More severe RLS symptom was proven to be an important factor to make a quality of life worsen.

  • PDF

Computation of Passive Earth Pressure Coefficient considering Logarithmic Spiral Arc (대수나선 파괴면을 고려한 수동토압계수의 계산)

  • Lee, Seung-Hyun
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.20 no.2
    • /
    • pp.425-433
    • /
    • 2019
  • In this study, a simple method of calculating the passive earth pressure coefficient, which is based on the limit equilibrium method, was proposed and the calculated earth pressure coefficients were compared with those of several researchers. The angle of the linear failure surface, which is combined with the logarithmic spiral arc, to the failure surfaces of the passive zone was derived and the whole passive thrust acting on the Rankine passive zone was considered in the proposed method instead of considering the horizontal component of passive thrust. The variations of the passive earth pressure coefficients of the proposed method showed the same tendency as that of the Coulomb's passive earth pressure coefficients with an inclined angle of backfill and internal friction angle. The magnitude of passive earth pressure coefficients of the proposed method were smaller than those of the Coulomb in almost all cases. A comparison of the passive earth pressure coefficients with the wall friction angle revealed the passive earth pressure coefficients of the proposed method to be smaller than those of the Coulomb and the differences between the two values increased with increasing internal friction angle and wall friction angle. A comparison of the passive earth pressure coefficients of the proposed method with those of the existing researchers for the considered internal friction angles of $25^{\circ}$, $30^{\circ}$, $35^{\circ}$, and $40^{\circ}$ and three wall friction angles revealed the maximum percentage differences for the Kerisel and Absi method, Soubra method, Lancellotta method, $Ant\tilde{a}o$ et al. method, Kame method, and Reddy et al. method to be 4.8%, 3.8%, 31.1%, 4.0%, 20.6%, and 12.8% respectively. The passive earth pressure coefficient and existing pressures were similar in all cases.

Electrochemical Characteristics of Cu3Si as Negative Electrode for Lithium Secondary Batteries at Elevated Temperatures (리튬 이차전지 음극용 Cu3Si의 고온에서의 전기화학적 특성)

  • Kwon, Ji-Y.;Ryu, Ji-Heon;Kim, Jun-Ho;Chae, Oh-B.;Oh, Seung-M.
    • Journal of the Korean Electrochemical Society
    • /
    • v.13 no.2
    • /
    • pp.116-122
    • /
    • 2010
  • A $Cu_3Si$ film electrode is obtained by Si deposition on a Cu foil using DC magnetron sputtering, which is followed by annealing at $800^{\circ}C$ for 10 h. The Si component in $Cu_3Si$ is inactive for lithiation at ambient temperature. The linear sweep thermammetry (LSTA) and galvano-static charge/discharge cycling, however, consistently illustrate that $Cu_3Si$ becomes active for the conversion-type lithiation reaction at elevated temperatures (> $85^{\circ}C$). The $Cu_3Si$ electrode that is short-circuited with Li metal for one week is converted to a mixture of $Li_{21}Si_5$ and metallic Cu, implying that the Li-Si alloy phase generated at 0.0 V (vs. Li/$Li^+$) at the quasi-equilibrium condition is the most Li-rich $Li_{21}Si_5$. However, the lithiation is not extended to this phase in the constant-current charging (transient or dynamic condition). Upon de-lithiation, the metallic Cu and Si react to be restored back to $Cu_3Si$. The $Cu_3Si$ electrode shows a better cycle performance than an amorphous Si electrode at $120^{\circ}C$, which can be ascribed to the favorable roles provided by the Cu component in $Cu_3Si$. The inactive element (Cu) plays as a buffer against the volume change of Si component, which can minimize the electrode failure by suppressing the detachment of Si from the Cu substrate.

Identification of Bovine Pregnancy-Specific Whey Proteins using Two-Dimensional Gel Electrophoresis

  • Han, Rong-Xun;Choi, Su-Min;Kim, Myung-Youn;Quan, Yan Shi;Kim, Baek-Chul;Diao, Yun Fei;Koqani, Reza;Park, Chang-Sik;Jin, Dong-Il
    • Reproductive and Developmental Biology
    • /
    • v.32 no.4
    • /
    • pp.255-261
    • /
    • 2008
  • The early diagnosis of bovine pregnancy is an essential component of successful reproductive planning on farms, because lack of bovine pregnancy over the long term results in reproductive failure and low milk yield-the latter of which is a special concern on dairy farms. This study was designed to identify early pregnancy-specific whey proteins in bovine, by comparing milk samples collected from cattle during pregnancy (Days 30 and 50) and from non-pregnant cattle. In this study, differentially expressed proteins in five pregnant and five non-pregnant Holstein dairy cattle were investigated and compared, using proteomics analysis. The first dimension was applied to a pH $3.0{\sim}10.0$ strip, by loading a 2-mg milk protein sample. After the second-dimension separation was performed, the gels were stained with colloidal Coomassie brilliant blue. The stained gels were scanned and the images were analyzed, to detect variations in protein spots between non-pregnant and pregnant cattle milk protein spots, using ImageMaster, this was followed by analysis with MALDI TOF-MS. Analysis of the 2-DE gel image resulted in a total of approximately $500{\sim}600$ protein spots, of which 12 spots were differentially expressed, six spots were up-regulated, and four spots were down-regulated; two spots were identified as pregnancy-specific proteins. These proteins were identified as lactoferrin, NA-DH dehydrogenase subunit 2, albumin, serum albumin precursor and transferrin. Our results via 2-D PAGE analysis revealed composite profiles of several milk proteins related to early bovine pregnancy, implying the possible use of these milk proteins in the early detection of bovine pregnancy.

Analysis of the Statistical Methods used in Scientific Research published in The Korean Journal of Culinary Research (한국조리학회지에 게재된 학술적 연구의 통계적 기법 분석)

  • Rha, Young-Ah;Na, Tae-Kyun
    • Culinary science and hospitality research
    • /
    • v.21 no.6
    • /
    • pp.49-62
    • /
    • 2015
  • Give that statistical analysis is an essential component of foodservice-related research, the purpose of this review is to analyse research trends of statistical methods applied to foodservice-related research. To achieve these objective, this study carried out a content analysis on a total of 251 out of 415 research articles published in The Korean Journal of Culinary Research(TKJCR) from January 2010 to December 2013. Of the total 164 research articles focussing on natural science research, qualitative research, articles written in English were excluded from the scope of this study. The results of this study are as follows. First, it turned out that 269 research articles applied quantitative research methods, and only 10 articles applied qualitative research methods among the 279 research articles based on social science research methods. Second, 20 article (8.0%) among the 251 did not specify the statistical methods or computer programs that were used for statistical analysis. Third, it was found that 228 articles (90.8%) used the SPSS program for data analysis. Fourth, in terms of frequency of use, it was revealed frequency analysis was most used, followed in order by reliability analysis, exploratory factor analysis, correlation analysis, regression analysis, structural equation modeling, confirmatory factor analysis, t-test, variance analysis, and cross tabs analysis, However, 3 out of 56 research articles that used a t-test did not suggest a t-value. 10 out of 64 articles that used ANOVA and demonstrated a significant difference in between-group mean did not conducted post-hoc test. Therefore, the researchers with interest in foodservice fields need to keep in mind that choosing and applying the correct statistical technique both determine the value and the success or failure of a study. To enhance the value and success of a study, it is necessary to use the proper statistical technique in an efficient way in order to prevent statistical errors.