• 한국건설관리학회:학술대회논문집
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• 한국건설관리학회 2003년도 학술대회지
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• pp.202-213
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• 2003

타워팰리스 III 현장은 현존하는 국내 건축물로는 가장 높은 초고층 주상복합건물이다. 초고층 현장에는 일반현장과는 다른 시공기술 및 엔지니어링 기술의 적용이 요구되는 바, 타워팰리스 III 현장은 지금까지 축적된 기술을 바탕으로 보다 발전된 시공기술과 엔지니어링 기술, 그리고 공정관리기법을 통하여 마감공사 포함 충 당 13.4일이라는 공사 속도를 달성하였다. 이와 같은 공사를 성공적으로 수행하기 위하여 적용된 첨단 시공기술로 1) 골조공사 및 외벽공사의 3-Day Cycle을 달성하기 위한 여러 가지 공법, 2) 초고층 주거건물의 마감공사 공정관리를 위한 Tact 공정관리 시스템, 3) 현장관리 시스템으로 물류관리 및 정보공유 시스템 등이 적용되었다. 또한 엔지니어링 요소기술로 1) 고유동 무다짐 콘크리트와 국내 최초의 압축강도 $800kgf/cm^{2}$의 초고강도 콘크리트 등의 New Material, 2) 냉각수 순환형 파이프쿨링 시스템 등의 New Method, 3) Smart Fan Control 주방환기 시스템을 포함한 Mechanical System 4) False Car System을 포함한 Electrical System 등이 있다.

• 한국지진공학회논문집
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• 제3권1호
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• pp.103-112
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• 1999

본 연구는 두 지점간의 진동수 응답함수를 이용하여 시간 및 진동수 영역에서의 원심펌프(20Hp. 50Hp) 가진력을 추정하기 위한 것이다. 진동수 응답함수는 실수부와 허수부에 대한 신호정보를 가지고 있으며 응답함수 역시 실수부와 허수부에 대한 신호정보를 가지고 있다 따라서 이들 진동수 응답함수 및 응답함숴의 복소수 계산으로부터 가진력을 실험적으로 구하였으며 이론적인 방법에 의하여 구한 가진력과 실험적으로 구한 값을 비교함으로서 펌프에 의한 주진동수 성분의 크기는 펌프 및 모터중량의 10-25% 정도가 됨을 제시하였다. 가진력 산정을 위한 시간영역에서의 불평형질량의 크기는 펌프 및 모터중량의 약 30-60%임을 알수 있었다 한편 펌프회전에 의한 진동은 주진동수 이외에도 주진동수의 2-3배의 크기를 갖는 성분이 있음을 알 수 있었으며 대상 콘크리트 슬래브의 고유진동수와의 가진진도수비를 달리함에 따라 정확한 진동전달률을 조절하는데 활용할 수 있다.

• 한국해양공학회지
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• 제28권2호
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• pp.160-166
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• 2014

Because of industrial development, industrial facilities are becoming more complex and diversified. Plant industries are focused on productivity improvement, cost reduction, and product uniformity by simplifying production processes using automated control. Furthermore, plant industries require higher pressures and temperatures to improve energy efficiency. For this reason, the valves used in plants are operated under harsh conditions. Globe valves and gate valves are mainly used for high pressure these days. However, these valves have various problems, including low maintainability and high cost, due to structural problems. Therefore, butterfly and ball valve applications are increasing in industrial plants. This paper suggests a quadruple-offset butterfly valve that is applicable to bi-direction use, and the principle design parameters are suggested. The selected design parameters are an eccentric flange center line and shaft centerline(Offset 1), an eccentric seat centerline and disc shaft centerline(Offset 2), the angle between the flange centerline and seat wedge angle(Offset 3), the angle between the vertical direction of the disc shaft centerline and seat centerline(Offset 4), and the seat engagement angle. To analyze the interaction effect of the design parameters, ANOM and ANOVA were performed with an orthogonal array. The parameters were found to have effects in the following order: Offset 2, Offset 1, engagement angle, Offset 3, and Offset 4. The interaction between the parameters was insignificant.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1996년도 제4회 추계심포지움
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• pp.65-73
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• 1996

LPS/LOS, the compound found only in gram-negative bacterial outer membrane, plays important roles in bacterial maintenance as well as its pathogenesis. We isolated and characterized several genes required for NTHi 2019 LOS biosynthesis, which encode enzymes required for sugar substrate synthesis or the transfer of substrates to receptor molecules. The htrB gene, however, appears to have more complex role. It has acryltransferase activity as well as various other activity, which may control regulation of LOS biosynthesis as well as its pathogenicity. Evidences supporting the latter come from the observations that the lipid A of the B29 induced significantly less TNF ${\alpha}$ from macrophages than that of the wild type LOS (unpublished data). H. influenzae A2-htrB mutant strain was also significantly less invasive than the wild type strain. The structural similarities of the enterobacterial LPS and the Haemophilus LOS enabled us to isolate the NTHi 2019 genes involved in LOS biosynthesis genes by using the S. typhimurium LPS deep core mutants. While a similar approach has been used for E. coli, this technique for selection of an LPS phenotype has not been applied to nonenterobacterial species. The difficulties inherent in the molecular manipulation of organism such as Neisseria and Haemophilus species make this approach particularly attractive in the identification and cloning LOS genes. Studies on genetic features of LPS/LOS biosynthesis would be useful for understanding bacterial pathogenesis as well as for developing vaccines for these gram-negative pathogenic bacteria.

• 한국결정성장학회:학술대회논문집
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• 한국결정성장학회 1996년도 제11차 KACG 학술발표회 Crystalline Particle Symposium (CPS)
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• pp.285-309
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• 1996

Non oxide ceramics such as nitrides of transition metals have shown significant potential for future economic impact, in diverse applications in ceramic, aerospace and electronic industries, as refractory products, abrasives and cutting tools, aircraft components, and semi-conductor substrates amid others. Combustion synthesis has become an attractive alternative to the conventional furnace technology to produce these materials cheaply, faster and at a higher level of purity. However he process os highly exothermic and manifests complex dynamics due to its strongly non-linear nature. In order to develop an understanding of this process and to study the effect of operational parameters on the final outcome, numerical modeling is necessary, which would generated essential knowledge to help scale-up the process. the model is based on a system of parabolic-hyperbolic partial differential equations representing the heat, mass and momentum conservation relations. The model also takes into account structural change due to sintering and volumetric expansion, and their effect on the transport properties of the system. The solutions of these equations exhibit steep moving spatial gradients in the form of reaction fronts, propagating in space with variable velocity, which gives rise to varying time scales. To cope with the possibility of extremely abrupt changes in the values of the solution over very short distances, adaptive mesh techniques can be applied to resolve the high activity regions by ordering grid points in appropriate places. To avoid a control volume formulation of the solution of partial differential equations, a simple orthogonal, adaptive-mesh technique is employed. This involves separate adaptation in the x and y directions. Through simple analysis and numerical examples, the adaptive mesh is shown to give significant increase in accuracy in the computations.

• 한국추진공학회지
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• 제21권1호
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• pp.8-16
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• 2017

고체 추진기관이 노즐마개에 의해 외기와의 교환이 완벽히 차단된다면, 구조적 안정성은 제작초기 조건인 내부조성간의 잔류반응(Post Cure, Migration etc.), 그리고 자유공간 내의 산소(또는 산화방지제)와 습기(제습제)와의 반응에 종속된다. 이로부터 발생하는 혼합형 고체추진제의 기계적 특성은 매우 복잡하며, 추진기관은 발사직전까지 일교차/년교차의 끊임없는 열하중을 받게 된다. 본 연구에서는 고체 추진기관의 제조공정인 성형오븐에서 출고 후 저장안정화까지의 거동을 고체추진제의 열유변학적 단순특성을 적용하여 신속하게 산출할 수 있는 방법을 제시하였다. 이를 위해 온도제어 가능한 Endurance Test 장치를 고안 제작하였으며, 추가적으로 점진적 응력과 변형율 증가에 따른 비선형 특성도 검토한다.

• Composites Research
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• 제35권1호
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• pp.23-30
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• 2022

폴리카보실란은 탄화규소 섬유 방사와 세라믹 제조를 위해 필요한 중요한 전구체이며, 이 전구체는 제조방법 및 공정에 따라 고내열성 및 내산화성 및 연속적인 탄화규소 섬유 생산 능력이 달라진다. 탄화규소 섬유는 폴리카보실란의 합성, 정제 및 분자구조제어기술, 그리고 이를 이용한 용융방사 및 안정화, 열처리 공정을 통해 제조된다. 본 논문에서는 폴리카보실란 전구체를 다양한 용매처리를 통하여 전구체 내에 존재하는 미반응물 및 저분자량의 정제효과를 파악하였으며, 또한 다양한 온도에서의 열처리에 따른 폴리카보실란 전구체의 중합 및 네트워크 재배열에 의한 변화에 대해 열적 분석을 실시하였다. 특히, 폴리카보실란 전구체의 유변물성 특성을 통해 용매처리 및 열처리에 따른 복합점도 및 구조적 배열의 변화를 분석하였다.

• 한국염색가공학회지
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• 제34권4호
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• pp.284-301
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• 2022

The limitations of food production caused by global warming, consumption of soil fertility, and land shortage have demanded the development of alternative foods. Their market has been increasing, and in particular, there is an urgent need for an alternative meat. Among them, the non-slaughtered cell-cultured meat that can be manufactured in the laboratory, that is, cultured meat, is in the spotlight, which can solve the problem of meat consumption while including the advantages of meat. It is classified into minced cultured meat and structured one with a structure similar to that of real meat. The latter is currently facing limitations related scaffolds, cells, and the multiplicative problems, and many attempts are being made to solve them. The complex problem is related to secure texture and taste as well as structural similarity to actual meat. To solve the problems, it is necessary to lay emphasis on cells, there are fat cells and vascular cells, and the most fundamental cells, muscle cells. These are the main cells that control the texture and nutrients of meat, and unlike other cells, they grow in the form of fibers. A myofibril (also known as a muscle fibril) is a basic rod-like organelle of a muscle cell, which is a quantitatively major component of meat, and one of the tissues that maintain the appearance of the body and bones. In this review article, we focused on the growth of muscle cells into long, tubular cells known as muscle fibers using the fabricated fibrous scaffold, and reviewed not only research results for muscle tissue engineering but also various results in the related fields for the last five years.

• 한국컴퓨터정보학회논문지
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• 제14권1호
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• pp.73-80
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• 2009

GPCR(Gprotein-coupled receptors) 패밀리(family)는 세포막 단백질로서, 외부 신호를 세포막을 경유하여 세포 내로 전달하는 신호전달 기전에서 중요한 역할을 담당한다. 그러나 GPCR마다 다양하고 복잡한 조절기전을 보이며 매우 특이적인 신호전달 기전을 가지는 것으로 알려져 있다. GPCR의 구조적인 특징과 패밀리 및 서브패밀리 등은 기능별로 잘 알려져 있는데 과거 GPCR을 찾아내는 연구 중에 가장 기본이 되는 일이 주어진 단백질 서열로부터 GPCR을 분류하는 일이다. 이미 발견된 GPCR들을 가지고 수학적인 모델을 이용하여 보다 정확하게 분류하는 연구가 주로 진행되어 왔다. 본 논문에서는 단백질의 기능이 입체적 구조에 의해 결정되는 점에 착안하여 두 GPCR의 아미노산 서열의 유사도가 낮은 경우에 그 2차 구조의 서열을 비교함으로써 기존의 발견된 GPCR의 데이터베이스에서 동일한 기능을 가졌을 것으로 추정되는 미지의 GPCR을 검출하는 방법을 제안한다.

• Journal of Microbiology and Biotechnology
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• 제33권8호
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• pp.1013-1022
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• 2023

Arbuscular mycorrhizal fungi (AMF) are widespread soil endophytic fungi, forming mutualistic relationships with the vast majority of land plants. Biochar (BC) has been reported to improve soil fertility and promote plant growth. However, limited studies are available concerning the combined effects of AMF and BC on soil community structure and plant growth. In this work, a pot experiment was designed to investigate the effects of AMF and BC on the rhizosphere microbial community of Allium fistulosum L. Using Illumina high-throughput sequencing, we showed that inoculation of AMF and BC had a significant impact on soil microbial community composition, diversity, and versatility. Increases were observed in both plant growth (the plant height by 8.6%, shoot fresh weight by 12.1%) and root morphological traits (average diameter by 20.5%). The phylogenetic tree also showed differences in the fungal community composition in A. fistulosum. In addition, Linear discriminant analysis (LDA) effect size (LEfSe) analysis revealed that 16 biomarkers were detected in the control (CK) and AMF treatment, while only 3 were detected in the AMF + BC treatment. Molecular ecological network analysis showed that the AMF + BC treatment group had a more complex network of fungal communities, as evidenced by higher average connectivity. The functional composition spectrum showed significant differences in the functional distribution of soil microbial communities among different fungal genera. The structural equation model (SEM) confirmed that AMF could improve the microbial multifunctionality by regulating the rhizosphere fungal diversity and soil properties. Our findings provide new information on the effects of AMF and biochar on plants and soil microbial communities.