• Maxillofacial Plastic and Reconstructive Surgery
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• v.36 no.4
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• pp.161-167
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• 2014

Purpose: The reconstruction of mandibular defects poses many difficulties due to the unique, complex shape of the mandible and the temporomandibular joints. With development of microvascular anastomosis, free tissue transplantation techniques, such as deep circumflex iliac artery (DCIA) flap and fibular free flap (FFF), were developed. The DCIA offers good quality and quantity of bone tissue for mandibular segmental defect and implant for dental rehabilitation. Virtual surgical planning (VSP) and stereolithography-guided osteotomy are currently successfully applied in three-dimensional mandibular reconstruction, but most use FFF. There are only a few articles on reconstruction with the DCIA that assess the postoperative results. Methods: Three patients admitted during a five month period (April of 2013 to August of 2013) underwent resection of mandible and DCIA musculo-osseous reconstruction using a VSP and stereolithographic modeling and assessment of outcomes included technical accuracy, esthetic contour, and functional outcomes. Results: This technique yielded iliac bone segment with excellent apposition and duplication of the preoperative plan. Flap survival was 100 percent and all patients maintained preoperative occlusion and contour. Conclusion: Based on our experience, we offer considerations and logically consistent protocols by classification of mandibular defects, and demonstrate the benefits in VSP and stereolithographic modeling of mandibular reconstructive surgery with DCIA flap.

• Restorative Dentistry and Endodontics
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• v.45 no.1
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• pp.7.1-7.9
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• 2020

Objectives: This study was performed to assess the anatomy of mandibular first molars. Materials and Methods: In this in vivo study, cone-beam computed tomography (CBCT) volumes of 312 bilateral intact first mandibular molars from 156 patients (79 men and 77 women; average age, 35.6 ± 11.2 years) were investigated in terms of the direction of each canal's curvature in the buccolingual and mesiodistal dimensions (direction of the position of the apex in relation to the longitudinal axis of the root), the presence of an isthmus (a narrow, ribbon-shaped communication between 2 root canals) in 3 segments (0-2, 2-4, and 4-6 mm) from the apex), and the presence and number of accessory canals (smaller canals besides the main root canals, connecting the pulp to the periodontium). Data were analyzed statistically (α = 0.05). Results: Mesiolingual canals were mostly buccally and distally inclined, while mesiobuccal and distolingual canals were mostly distally curved. Isthmuses were more common in younger patients (χ² test, p < 0.05). The average numbers of accessory canals in the apical, middle, and coronal segments were 9.9 ± 4.2, 6.9 ± 2.9, and 9.3 ± 3.0 canals per segment, respectively (analysis of variance, p < 0.001). Age and sex were not associated with the number of accessory canals (p > 0.05). Conclusions: The complex anatomy of these teeth deserves attention during non-surgical or surgical endodontic treatment. Around the apex, isthmuses might be more prevalent in younger and female individuals.

• Speech Sciences
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• v.11 no.2
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• pp.71-87
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• 2004

Korean has a pair of voiceless fricatives, whose laryngeal manifestation comes in parallel to stops and affricates with a three-way lexical contrast. Prior phonetic studies by Kagaya (1974), Iverson (1983), and Kang (1999, 2000) point out /s/ is associated with multiple characteristics of the larynx shared with not only the lax but also the aspirated series, whereas /s' / carries a laryngeal distinction typical of the tense consonants. The complex dual nature of /s/ is again supported by a psycholinguistic study by Kang (2004), as /s/ was found to interact with /$c^h$/ (17% of the time) as well as /c/ (57%) in speech errors. In addition, a recent work by Cho and Lee (2003) notes an interesting chain shift case in the acquisition of the fricatives. Although they observed a significant phonological pattern between child English and Korean, Cho and Lee's description of acquiring fricatives is far from being precise from the perspective of phonetics. From a longitudinal study of recorded tapes by two children at 1;7-3;8 and 1;7-2;1 respectively, I found that /s' / was usually substituted into tense noncontinuants in young children's early production as predicted, whereas /s/ having both lax and aspirated-like glottal properties revealed a complicated pattern of substitutions into lax, tense, and aspirated noncontinuants with a varying degree of preference relative to the subjects. The current acquisition study supports the previous claims concerning fricatives in other languages, showing that their acquisition comes after stops. Besides, it also notes that Korean fricatives are subject to a series of phonological processes called stopping, affricating, tensifying and palatalizing during the transitional period of phonological development by young children. Moreover, between the two voiceless types, /s/ was acquired earlier than /s'/ as the unmarked segment.

• Archives of Plastic Surgery
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• v.44 no.1
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• pp.19-25
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• 2017

Background Numerous condylar repositioning methods have been reported. However, most of them are 2-dimensional or are complex procedures that require a longer operation time and a highly trained surgeon. This study aims to introduce a new technique using a condylar repositioning plate and a centric relation splint to achieve a centric relationship. Methods We evaluated 387 patients who had undergone surgery for skeletal jaw deformities. During the operation, a centric relation splint, intermediate splint, final centric occlusion splint, and condylar repositioning plate along with an L-type mini-plate for LeFort I osteotomy or a bicortical screw for bilateral sagittal split ramus osteotomy were utilized for rigid fixation. The evaluation included: a physical examination to detect preoperative and postoperative temporomandibular joint dysfunction, 3-dimensional computed tomography and oblique transcranial temporomandibular joint radiography to measure 3-dimensional condylar head movement, and posteroanterior and lateral cephalometric radiography to measure the preoperative and postoperative movement of the bony segment and relapse rate. Results A 0.3% relapse rate was observed in the coronal plane, and a 2.8% relapse rate in the sagittal plane, which is indistinguishable from the dental relapse rate in orthodontic treatment. The condylar repositioning plate could not fully prevent movement of the condylar head, but the relapse rate was minimal, implying that the movement of the condylar head was within tolerable limits. Conclusions Our condylar repositioning method using a centric relation splint and miniplate in orthognathic surgery was found to be simple and effective for patients suffering from skeletal jaw deformities.

• The Journal of Engineering Geology
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• v.24 no.4
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• pp.511-523
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• 2014

Limit equilibrium analysis and finite difference analysis were used to evaluate slope stability in the in Gohan, Korea, which is affected by large-scale tensile cracks and uplift. There is a thick colluvial layer in the study area and predicting ground behavior is problematic because the presence of clay makes it difficult to determine the strength parameters of the soil. Consequently, a numerical model able to reflect the collapse properties of the site was required that applied the modified boundary layer model and calculated the strength parameters using back analysis. The numerical simulation results that consider the strength parameter one does with the present situation the establishment of the pile is completed, and the simulation is able to asses ground stability in complex terrain in a reliable manner. Also the somewhat it judges with the fact that it will be able to provide the fundamental data which secures the stability of the segment where it is unstable.

• Earthquakes and Structures
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• v.10 no.6
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• pp.1253-1272
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• 2016

For a nonlinear control system, there are many uncertainties, such as the structural model, controlled parameters and external loads. Although the significant progress has been achieved on the robust control of nonlinear systems through some researches on this issue, there are still some limitations, for instance, the complicated solving process, weak conservatism of system, involuted structures and high order of controllers. In this study, the computational structural mechanics and optimal control theory are adopted to address above problems. The induced norm is the eigenvalue problem in structural mechanics, i.e., the elastic stable Euler critical force or eigenfrequency of structural system. The segment mixed energy is introduced with a precise integration and an extended Wittrick-Williams (W-W) induced norm calculation method. This is then incorporated in the market-based control (MBC) theory and combined with the force analogy method (FAM) to solve the MBC robust strategy (R-MBC) of nonlinear systems. Finally, a single-degree-of-freedom (SDOF) system and a 9-stories steel frame structure are analyzed. The results are compared with those calculated by the $H{\infty}$-robust (R-$H{\infty}$) algorithm, and show the induced norm leads to the infinite control output as soon as it reaches the critical value. The R-MBC strategy has a better control effect than the R-$H{\infty}$ algorithm and has the advantage of strong strain capacity and short online computation time. Thus, it can be applied to large complex structures.

• BMB Reports
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• v.35 no.2
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• pp.206-212
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• 2002

The NS2B-NS3(pro) polyprotein segment from the dengue virus serotype 2 strain 16681 was purified from overexpressing E. coli by metal chelate affinity chromatography and gel filtration. Enzymatic activity of the refolded NS2B-NS3(pro) protease complex was determined in vitro with dansyl-labeled peptide substrates, based upon native dengue virus type 2 cleavage sites. The 12mer substrate peptides and the cleavage products could be separated by reversed-phase HPLC, and were identified by UV and fluorescence detection. All of the peptide substrates (representing the DEN polyprotein junction sequences at the NS2A/NS2B, NS2B/NS3, NS3/NS4A and NS4B/NS5 sites) were cleaved by the recombinant protease NS2B-NS3(pro). No cleavage was observed with an enzymatically inactive S135A mutant of the NS3 protein, or with a modified substrate peptide of the NS3/NS4A polyprotein site that contained a K2093A substitution. Enzymatic activity was dependent on the salt concentration. A 50% decrease of activity was observed in the presence of 0.1M sodium chloride. Our results show that the NS3 protease activity of the refolded NS2B-NS3(pro) protein can be assayed in vitro with high specificity by using cleavage-junction derived peptide substrates.

• Journal of the Korean Geotechnical Society
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• v.19 no.3
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• pp.93-104
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• 2003

The Disturbed State Concept (DSC) model, with simplified unloading/reloading formulation, is implemented in a nonlinear dynamic finite element program fur porous media named DSC_DYN2D. In this research, the DSC constitutive model is utilized using the HiSS model for relative intact (RI) part and the critical state model for the fully adjusted (FA) part in the material. The general formulation for implementation is developed. The cyclic loading tests from the field load test data on a pile segment were numerically simulated using the finite element program DSC_DYN2D and compared with field measurements and those from the previous analysis with the HiSS model. The DSC predictions show improved agreement with the field behavior of the pile compared to those from the HiSS model. Overall, the computer procedure with the DSC model allows improved and realistic simulation of the complex dynamic soil-structure interaction problems.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.8A
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• pp.805-813
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• 2002

Document image should be classified into detailed regions as text, picture, table and etc through the geometric layout analysis if paper documents can be converted automatically into electronic documents. However, complexity of the document layout and variety of the size and density of a picture are the reason to make it difficult to analyze the geometric layout of the document images. In this paper, we propose the method which have a better performance of the region segmentation and classifications, and the line extraction in the table region than the commercial softwares and previous methods. The proposed method can segment the document into detailed regions by using connected components method even if its layout is complex. This method also classifies texts and pictures by using separable median filter even. Though their size and density are diverse, In addition, this method extracts the lines from the table adapting one dimensional median filter to the each horizontal and vertical direction, even though lines are deformed or texts attached to them.

• Journal of Chest Surgery
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• v.28 no.7
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• pp.658-665
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• 1995

Between March 1989 and December 1994, one-stage repair was performed for correction of the intracardiac malformations associated with aortic coarctation in 34 patients or interrupted aortic arch in 8 patients via median sternotomy. There were 26 male and 16 female patients, and their body weight ranged from 1.8 to 8kg[mean weight, 4.0$\pm$l.4kg . The age at the operation ranged from 7 days to 18 months [mean age, 3.1$\pm$3.8 months . The repair of aortic coarctation or interrupted aortic arch was performed using extended end-to-end anastomosis in most of the patients[86%, 36/42 , and six patients underwent ductal tissue excision and patch aortoplasty. Intracardiac defects were corrected concomitantly through the right atrium unless the anatomy dictated otherwise. Obstructive outlet septurn was resected whenever necessary. There were seven early deaths[16.8% , and three late deaths with a mean follow-up period of 25 months [range from 1 to 65 months . Three patients were reoperated upon residual subaortic stenosis,stenosis at the RPA origin, and subacute bacterial endocarditis respectively. None showed any significant residual or anastomotic stenosis postoperatively. One stage repair of the aortic coarctation and interrupted aortic arch associated with intracardiac defect leaves no native coarctation shelf tissue or residual hypoplasia in the repaired segment, has low incidence of recurrent or residual stenosis, minimizes reoperation and incisions, and manages arch hypoplasia easily.We conclude that surgical results of one-stage repair for the intracardiac malformation associated with aortic coarctation or interrupted aortic arch are resonable.